Research Topics
| R A WhitmerSummaryAffiliation: Kaiser Permanente Country: USA Publications
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Detail Information
Publications
Hormone replacement therapy and cognitive performance: the role of homocysteineRachel A Whitmer
School of Public Health, University of California at Berkeley, Kaiser Permanente Medical Care Program, Oakland, USA
J Gerontol A Biol Sci Med Sci 58:324-30. 2003..The aim of this study was to examine whether the association between homocysteine and cognitive functioning varies by use of hormone replacement therapy (HRT) in postmenopausal women...
Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitusRachel A Whitmer
Kaiser Permanente, Division of Research, Section of Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
JAMA 301:1565-72. 2009..Although acute hypoglycemia may be associated with cognitive impairment in children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a risk factor for dementia in older patients with type 2 diabetes...
Timing of hormone therapy and dementia: the critical window theory revisitedRachel A Whitmer
Division of Research, Kaiser Permanente of Northern California, Oakland, CA, USA
Ann Neurol 69:163-9. 2011..Our objective was to compare HT use in midlife with that in late life on risk of dementia among 5,504 postmenopausal female members of an integrated healthcare delivery system...
Midlife cardiovascular risk factors and risk of dementia in late lifeR A Whitmer
Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
Neurology 64:277-81. 2005..To evaluate if midlife cardiovascular risk factors are associated with risk of late-life dementia in a large, diverse cohort...
Obesity in middle age and future risk of dementia: a 27 year longitudinal population based studyRachel A Whitmer
Division of Research, Kaiser Permanente, Oakland, CA 94612, USA
BMJ 330:1360. 2005..To evaluate any association between obesity in middle age, measured by body mass index and skinfold thickness, and risk of dementia later in life...
Central obesity and increased risk of dementia more than three decades laterR A Whitmer
Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
Neurology 71:1057-64. 2008..No studies have evaluated whether the same pattern exists with dementia. The objective was to evaluate the association between midlife central obesity and risk of dementia three decades later...
Do long-term HDL-C declines associated with a first birth vary by apo E phenotype? The Coronary Artery Risk Development in Young Adults (CARDIA) studyErica P Gunderson
Kaiser Permanente Division of Research, Etiology and Prevention, Kaiser Permanente, Oakland, California 94612, USA
J Womens Health (Larchmt) 14:917-28. 2005..Because endogenous sex hormones markedly increase during pregnancy, we examined whether HDL-C declines after a first birth varied by apo E polymorphisms...
Lactation and changes in maternal metabolic risk factorsErica P Gunderson
Division of Research, Epidemiology and Prevention Section, Kaiser Permanente, Oakland, California 94612, USA
Obstet Gynecol 109:729-38. 2007..To examine the relationship between duration of lactation and changes in maternal metabolic risk factors...
Childbearing may increase visceral adipose tissue independent of overall increase in body fatErica P Gunderson
Division of Research, Epidemiology and Prevention Section, Kaiser Permanente, Oakland, California, USA
Obesity (Silver Spring) 16:1078-84. 2008..To examine whether childbearing is associated with increased visceral adiposity and whether the increase is proportionally larger than other depots...
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on AgingMary N Haan
Epidemiology Program, School of Public Health, University of Michigan, Ann Arbor, MI 48104, USA
Am J Clin Nutr 85:511-7. 2007..High concentrations of homocysteine have been linked to a greater risk of Alzheimer disease, dementia, and cognitive decline...
Type 2 diabetes and risk of cognitive impairment and dementiaRachel A Whitmer
Kaiser Permanente Division of Research, Epidemiology Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
Curr Neurol Neurosci Rep 7:373-80. 2007..This paper presents a review of the evidence on diabetes and increased risk of dementia and cognitive impairment, a discussion of different possible mechanisms, and remaining gaps in our knowledge...
Metabolic syndrome and cognitive decline in elderly Latinos: findings from the Sacramento Area Latino Study of Aging studyKristine Yaffe
Department of Psychiatry, University of California at San Francisco, San Francisco VA Medical Center, San Francisco, CA, USA
J Am Geriatr Soc 55:758-62. 2007..To investigate the effect of metabolic syndrome on cognitive function in an elderly Latino population and to determine whether inflammation modifies this association...
The epidemiology of adiposity and dementiaRachel A Whitmer
Kaiser Permanente Division of Research, Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
Curr Alzheimer Res 4:117-22. 2007..Mechanistic pathways such as adipocyte secreted proteins and hormones, and inflammatory cytokines could explain the association between obesity and increased risk of dementia...
Body mass index in midlife and risk of Alzheimer disease and vascular dementiaRachel A Whitmer
Kaiser Permanente Division of Research, Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
Curr Alzheimer Res 4:103-9. 2007..Future studies need to unveil the mechanisms between adiposity and excess risk of AD and VaD...
Statin use and risk of prostate cancer in the California Men's Health Study cohortE Dawn Flick
Division of Research, Kaiser Permanente, 2000 Broadway, 5th Floor, Oakland, CA 94612, USA
Cancer Epidemiol Biomarkers Prev 16:2218-25. 2007..Our findings suggest that long-term statin use might be associated with a reduced risk of prostate cancer but perhaps only among regular nonsteroidal anti-inflammatory drug users...
Midlife obesity and long-term risk of nursing home admissionJacob S Elkins
Department of Neurology, University of California, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143, USA
Obesity (Silver Spring) 14:1472-8. 2006..We investigated whether obesity in middle-aged individuals influences the need for future nursing home care and whether the risk of nursing home admission associated with obesity is greater in whites than in blacks...
Physical activity and dementia: The need for prevention trialsDeborah E Barnes
Department of Psychiatry, University of California, San Francisco, CA 94121, USA
Exerc Sport Sci Rev 35:24-9. 2007..This review summarizes the evidence that physical activity is associated with a reduced risk of dementia in older adults and recommends that prevention trials be performed to determine whether this association is causal...
