R A Whitmer

Summary

Affiliation: Kaiser Permanente
Country: USA

Publications

  1. doi request reprint Racial/Ethnic differences in dementia risk among older type 2 diabetic patients: the diabetes and aging study
    Elizabeth R Mayeda
    Corresponding author Rachel A Whitmer
    Diabetes Care 37:1009-15. 2014
  2. doi request reprint Central obesity and increased risk of dementia more than three decades later
    R A Whitmer
    Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
    Neurology 71:1057-64. 2008
  3. ncbi request reprint Type 2 diabetes and risk of cognitive impairment and dementia
    Rachel A Whitmer
    Kaiser Permanente Division of Research, Epidemiology Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    Curr Neurol Neurosci Rep 7:373-80. 2007
  4. ncbi request reprint The epidemiology of adiposity and dementia
    Rachel A Whitmer
    Kaiser Permanente Division of Research, Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    Curr Alzheimer Res 4:117-22. 2007
  5. ncbi request reprint Body mass index in midlife and risk of Alzheimer disease and vascular dementia
    Rachel A Whitmer
    Kaiser Permanente Division of Research, Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    Curr Alzheimer Res 4:103-9. 2007
  6. ncbi request reprint Midlife cardiovascular risk factors and risk of dementia in late life
    R A Whitmer
    Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
    Neurology 64:277-81. 2005
  7. pmc Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus
    Rachel A Whitmer
    Kaiser Permanente, Division of Research, Section of Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    JAMA 301:1565-72. 2009
  8. pmc Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study
    Rachel A Whitmer
    Division of Research, Kaiser Permanente, Oakland, CA 94612, USA
    BMJ 330:1360. 2005
  9. doi request reprint Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia
    Minna Rusanen
    Department of Neurology, University of Eastern Finland, Kuopio, Finland
    Arch Intern Med 171:333-9. 2011
  10. pmc Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging
    Mary N Haan
    Epidemiology Program, School of Public Health, University of Michigan, Ann Arbor, MI 48104, USA
    Am J Clin Nutr 85:511-7. 2007

Research Grants

  1. Obesity, Adipocytokines and Cognitive Aging
    RACHEL WHITMER; Fiscal Year: 2007
  2. Epidemiology of Glycemia Inflammation & Cognition
    RACHEL WHITMER; Fiscal Year: 2007

Detail Information

Publications16

  1. doi request reprint Racial/Ethnic differences in dementia risk among older type 2 diabetic patients: the diabetes and aging study
    Elizabeth R Mayeda
    Corresponding author Rachel A Whitmer
    Diabetes Care 37:1009-15. 2014
    ..Adjustment for sociodemographics, diabetes-related complications, and markers of clinical control did not explain observed differences. Future studies should investigate why these differences exist and ways to reduce them. ..
  2. doi request reprint Central obesity and increased risk of dementia more than three decades later
    R A Whitmer
    Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
    Neurology 71:1057-64. 2008
    ..No studies have evaluated whether the same pattern exists with dementia. The objective was to evaluate the association between midlife central obesity and risk of dementia three decades later...
  3. ncbi request reprint Type 2 diabetes and risk of cognitive impairment and dementia
    Rachel A Whitmer
    Kaiser Permanente Division of Research, Epidemiology Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    Curr Neurol Neurosci Rep 7:373-80. 2007
    ..This paper presents a review of the evidence on diabetes and increased risk of dementia and cognitive impairment, a discussion of different possible mechanisms, and remaining gaps in our knowledge...
  4. ncbi request reprint The epidemiology of adiposity and dementia
    Rachel A Whitmer
    Kaiser Permanente Division of Research, Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    Curr Alzheimer Res 4:117-22. 2007
    ..Mechanistic pathways such as adipocyte secreted proteins and hormones, and inflammatory cytokines could explain the association between obesity and increased risk of dementia...
  5. ncbi request reprint Body mass index in midlife and risk of Alzheimer disease and vascular dementia
    Rachel A Whitmer
    Kaiser Permanente Division of Research, Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    Curr Alzheimer Res 4:103-9. 2007
    ..Future studies need to unveil the mechanisms between adiposity and excess risk of AD and VaD...
  6. ncbi request reprint Midlife cardiovascular risk factors and risk of dementia in late life
    R A Whitmer
    Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
    Neurology 64:277-81. 2005
    ..To evaluate if midlife cardiovascular risk factors are associated with risk of late-life dementia in a large, diverse cohort...
  7. pmc Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus
    Rachel A Whitmer
    Kaiser Permanente, Division of Research, Section of Etiology and Prevention, 2000 Broadway, Oakland, CA 94612, USA
    JAMA 301:1565-72. 2009
    ..Although acute hypoglycemia may be associated with cognitive impairment in children with type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a risk factor for dementia in older patients with type 2 diabetes...
  8. pmc Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study
    Rachel A Whitmer
    Division of Research, Kaiser Permanente, Oakland, CA 94612, USA
    BMJ 330:1360. 2005
    ..To evaluate any association between obesity in middle age, measured by body mass index and skinfold thickness, and risk of dementia later in life...
  9. doi request reprint Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia
    Minna Rusanen
    Department of Neurology, University of Eastern Finland, Kuopio, Finland
    Arch Intern Med 171:333-9. 2011
    ..Our objective was to investigate the long-term association of amount of smoking in middle age on the risk of dementia, Alzheimer disease (AD), and vascular dementia (VaD) several decades later in a large, diverse population...
  10. pmc Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging
    Mary N Haan
    Epidemiology Program, School of Public Health, University of Michigan, Ann Arbor, MI 48104, USA
    Am J Clin Nutr 85:511-7. 2007
    ..High concentrations of homocysteine have been linked to a greater risk of Alzheimer disease, dementia, and cognitive decline...
  11. ncbi request reprint Metabolic syndrome and cognitive decline in elderly Latinos: findings from the Sacramento Area Latino Study of Aging study
    Kristine Yaffe
    Department of Psychiatry, University of California at San Francisco, San Francisco VA Medical Center, San Francisco, CA, USA
    J Am Geriatr Soc 55:758-62. 2007
    ..To investigate the effect of metabolic syndrome on cognitive function in an elderly Latino population and to determine whether inflammation modifies this association...
  12. ncbi request reprint Midlife obesity and long-term risk of nursing home admission
    Jacob S Elkins
    Department of Neurology, University of California, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143, USA
    Obesity (Silver Spring) 14:1472-8. 2006
    ..We investigated whether obesity in middle-aged individuals influences the need for future nursing home care and whether the risk of nursing home admission associated with obesity is greater in whites than in blacks...
  13. ncbi request reprint Statin use and risk of prostate cancer in the California Men's Health Study cohort
    E Dawn Flick
    Division of Research, Kaiser Permanente, 2000 Broadway, 5th Floor, Oakland, CA 94612, USA
    Cancer Epidemiol Biomarkers Prev 16:2218-25. 2007
    ..Our findings suggest that long-term statin use might be associated with a reduced risk of prostate cancer but perhaps only among regular nonsteroidal anti-inflammatory drug users...
  14. pmc Do long-term HDL-C declines associated with a first birth vary by apo E phenotype? The Coronary Artery Risk Development in Young Adults (CARDIA) study
    Erica P Gunderson
    Kaiser Permanente Division of Research, Etiology and Prevention, Kaiser Permanente, Oakland, California 94612, USA
    J Womens Health (Larchmt) 14:917-28. 2005
    ..Because endogenous sex hormones markedly increase during pregnancy, we examined whether HDL-C declines after a first birth varied by apo E polymorphisms...
  15. ncbi request reprint Physical activity and dementia: The need for prevention trials
    Deborah E Barnes
    Department of Psychiatry, University of California, San Francisco, CA 94121, USA
    Exerc Sport Sci Rev 35:24-9. 2007
    ..This review summarizes the evidence that physical activity is associated with a reduced risk of dementia in older adults and recommends that prevention trials be performed to determine whether this association is causal...
  16. pmc Childbearing may increase visceral adipose tissue independent of overall increase in body fat
    Erica P Gunderson
    Division of Research, Epidemiology and Prevention Section, Kaiser Permanente, Oakland, California, USA
    Obesity (Silver Spring) 16:1078-84. 2008
    ..To examine whether childbearing is associated with increased visceral adiposity and whether the increase is proportionally larger than other depots...

Research Grants3

  1. Obesity, Adipocytokines and Cognitive Aging
    RACHEL WHITMER; Fiscal Year: 2007
    ..Since Latinos are at a higher risk for diabetes, and are more likely to have visceral adiposity, this is an important group in which to characterize the potential role of adipocytokines on cognition and cognitive decline. ..
  2. Epidemiology of Glycemia Inflammation & Cognition
    RACHEL WHITMER; Fiscal Year: 2007
    ..abstract_text> ..