G A Nichols

Summary

Affiliation: Kaiser Permanente
Country: USA

Publications

  1. doi request reprint Glycemic control and risk of cardiovascular disease hospitalization and all-cause mortality
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    J Am Coll Cardiol 62:121-7. 2013
  2. pmc Independent contribution of A1C, systolic blood pressure, and LDL cholesterol control to risk of cardiovascular disease hospitalizations in type 2 diabetes: an observational cohort study
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR, USA
    J Gen Intern Med 28:691-7. 2013
  3. doi request reprint Hospital use and medical care costs up to 5 years after triglyceride lowering among patients with severe hypertriglyceridemia
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    J Clin Lipidol 6:443-9. 2012
  4. pmc Construction of a multisite DataLink using electronic health records for the identification, surveillance, prevention, and management of diabetes mellitus: the SUPREME-DM project
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227, USA
    Prev Chronic Dis 9:E110. 2012
  5. pmc Glycemic response and attainment of A1C goals following newly initiated insulin therapy for type 2 diabetes
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Diabetes Care 35:495-7. 2012
  6. doi request reprint Comparison of evidence-based versus non-evidence-based pharmacotherapy on the risk of cardiovascular hospitalization and all-cause mortality among patients with established cardiovascular disease
    Gregory A Nichols
    Kaiser Permanente, Center for Health Research, Portland, Oregon, USA
    Am J Cardiol 105:786-91. 2010
  7. ncbi request reprint The association between fibrate use, change in high-density lipoprotein cholesterol, and the risk of cardiovascular disease: a retrospective chart review involving up to 8 years of follow-up
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Clin Ther 28:243-50. 2006
  8. pmc Progression from newly acquired impaired fasting glusose to type 2 diabetes
    Gregory A Nichols
    Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    Diabetes Care 30:228-33. 2007
  9. ncbi request reprint Treatment escalation and rise in HbA1c following successful initial metformin therapy
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    Diabetes Care 29:504-9. 2006
  10. doi request reprint Diabetes incidence for all possible combinations of metabolic syndrome components
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1098, USA
    Diabetes Res Clin Pract 90:115-21. 2010

Research Grants

Detail Information

Publications63

  1. doi request reprint Glycemic control and risk of cardiovascular disease hospitalization and all-cause mortality
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    J Am Coll Cardiol 62:121-7. 2013
    ..This study sought to evaluate the relationship between glycemic control and cardiovascular disease (CVD) hospitalizations and all-cause mortality among patients with type 2 diabetes in a real-world setting...
  2. pmc Independent contribution of A1C, systolic blood pressure, and LDL cholesterol control to risk of cardiovascular disease hospitalizations in type 2 diabetes: an observational cohort study
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR, USA
    J Gen Intern Med 28:691-7. 2013
    ..Cardiovascular disease (CVD) prevention in diabetes requires broad-based treatment of dyslipidemia, hypertension, and hyperglycemia. The independent contribution of all combinations of risk factor control to CVD risk has not been evaluated...
  3. doi request reprint Hospital use and medical care costs up to 5 years after triglyceride lowering among patients with severe hypertriglyceridemia
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    J Clin Lipidol 6:443-9. 2012
    ..Severe hypertriglyceridemia is associated with resource-intensive conditions such as cardiovascular disease, diabetes, and pancreatitis. Whether triglyceride (TG) reduction reduces annual medical costs has not been studied...
  4. pmc Construction of a multisite DataLink using electronic health records for the identification, surveillance, prevention, and management of diabetes mellitus: the SUPREME-DM project
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227, USA
    Prev Chronic Dis 9:E110. 2012
    ....
  5. pmc Glycemic response and attainment of A1C goals following newly initiated insulin therapy for type 2 diabetes
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Diabetes Care 35:495-7. 2012
    ..To identify the characteristics associated with glycemic response to newly initiated insulin therapy...
  6. doi request reprint Comparison of evidence-based versus non-evidence-based pharmacotherapy on the risk of cardiovascular hospitalization and all-cause mortality among patients with established cardiovascular disease
    Gregory A Nichols
    Kaiser Permanente, Center for Health Research, Portland, Oregon, USA
    Am J Cardiol 105:786-91. 2010
    ..92, 95% CI 0.83 to 1.01, p = 0.067). In conclusion, treatment according to current guidelines was significantly associated with reduced mortality but not the risk of secondary hospitalizations...
  7. ncbi request reprint The association between fibrate use, change in high-density lipoprotein cholesterol, and the risk of cardiovascular disease: a retrospective chart review involving up to 8 years of follow-up
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Clin Ther 28:243-50. 2006
    ..However, whether fibrates provide a CVD risk reduction independent of changes in the traditional lipoprotein fractions and other known CVD risk factors is not clear...
  8. pmc Progression from newly acquired impaired fasting glusose to type 2 diabetes
    Gregory A Nichols
    Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    Diabetes Care 30:228-33. 2007
    ..We sought to estimate the rate of progression from newly acquired (incident) impaired fasting glucose (IFG) to diabetes under the old and new IFG criteria and to identify predictors of progression to diabetes...
  9. ncbi request reprint Treatment escalation and rise in HbA1c following successful initial metformin therapy
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    Diabetes Care 29:504-9. 2006
    ..To describe secondary failure of initial metformin therapy in patients who achieved initial HbA(1c) (A1C) <8% and to identify predictors of failure...
  10. doi request reprint Diabetes incidence for all possible combinations of metabolic syndrome components
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1098, USA
    Diabetes Res Clin Pract 90:115-21. 2010
    ..Because metabolic syndrome (MetS) is defined as any three of five criteria, not all persons with MetS have the same risk factors. Whether the combinations of criteria confer equal diabetes risk is unknown...
  11. pmc Delay of insulin addition to oral combination therapy despite inadequate glycemic control: delay of insulin therapy
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1098, USA
    J Gen Intern Med 22:453-8. 2007
    ..Patients and providers may be reluctant to escalate to insulin therapy despite inadequate glycemic control...
  12. ncbi request reprint Weight changes following the initiation of new anti-hyperglycaemic therapies
    G A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR, USA
    Diabetes Obes Metab 9:96-102. 2007
    ....
  13. ncbi request reprint Validating the Framingham Offspring Study equations for predicting incident diabetes mellitus
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227 1098, USA
    Am J Manag Care 14:574-80. 2008
    ..Investigators from the Framingham Offspring Study (FOS) recently proposed a new simple point score for estimating 8-year diabetes mellitus (DM) risk...
  14. ncbi request reprint Complications of dysglycemia and medical costs associated with nondiabetic hyperglycemia
    Gregory A Nichols
    Center for Health Research, Kaiser Permanente, Portland, OR 97227 1098, USA
    Am J Manag Care 14:791-8. 2008
    ..To estimate the prevalence of complications associated with diabetes in patients with hyperglycemia below the threshold for diabetes, and to evaluate the associated medical costs...
  15. pmc Independent contribution of diabetes to increased prevalence and incidence of atrial fibrillation
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Diabetes Care 32:1851-6. 2009
    ..We sought to compare the prevalence and incidence of atrial fibrillation in age- and sex-matched patients with and without type 2 diabetes...
  16. doi request reprint Normal fasting plasma glucose and risk of type 2 diabetes diagnosis
    Gregory A Nichols
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227 1098, USA
    Am J Med 121:519-24. 2008
    ..The study compares the risk of incident diabetes associated with fasting plasma glucose levels in the normal range, controlling for other risk factors...
  17. doi request reprint The incidence of heart failure among nondiabetic patients with and without impaired fasting glucose
    Gregory A Nichols
    Kaiser Permanente, Center for Health Research, Portland, OR 97227 1098, USA
    J Diabetes Complications 23:224-8. 2009
    ..The purpose of this study was to elucidate the relationship between fasting plasma glucose (FPG), development of diabetes, and incident heart failure (HF) in a large, community sample of nondiabetic subjects...
  18. ncbi request reprint Does statin therapy initiation increase the risk for myopathy? An observational study of 32,225 diabetic and nondiabetic patients
    Gregory A Nichols
    Kaiser Permanente, Center for Health Research, Portland, Oregon 97227 1098, USA
    Clin Ther 29:1761-70. 2007
    ..Estimates of myopathy rates in the literature are based on adverse events reported in clinical trials, which may not be representative of the clinical practice setting...
  19. ncbi request reprint Intensity of lipid-lowering therapy and low-density lipoprotein cholesterol goal attainment among the elderly before and after the 2004 National Cholesterol Education Program Adult Treatment Panel III update
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1098, USA
    Am Heart J 154:554-60. 2007
    ..Our objectives were to compare the proportion of elderly patients receiving intensive or minimal-guideline lipid-lowering therapy and the proportions meeting low-density lipoprotein cholesterol (LDL-C) goals before and after the update...
  20. doi request reprint Successes and challenges of insulin therapy for type 2 diabetes in a managed-care setting
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1098, USA
    Curr Med Res Opin 26:9-15. 2010
    ....
  21. doi request reprint Frequency of obtaining national cholesterol education program adult treatment panel III goals for all major serum lipoproteins after initiation of lipid altering therapy
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Am J Cardiol 104:1689-94. 2009
    ..About half the patients starting statins could be candidates for additional therapy targeting non-LDL cholesterol lipid fractions...
  22. pmc Higher medical care costs accompany impaired fasting glucose
    Gregory A Nichols
    Kaiser PermanenteCenter for Health Research, 3800 N Interstate Ave, Portland, Oregon 97227 1098, USA
    Diabetes Care 28:2223-9. 2005
    ....
  23. ncbi request reprint The incidence of congestive heart failure associated with antidiabetic therapies
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1098, USA
    Diabetes Metab Res Rev 21:51-7. 2005
    ..Our objectives were to estimate the CHF risk associated with specific therapies for diabetes and to determine the differences in incidence rates of CHF associated with adding various antidiabetic agents...
  24. ncbi request reprint Medical care costs among patients with established cardiovascular disease
    Gregory A Nichols
    Center for Health Research, Kaiser Permanente, Portland, OR 97227 1098, USA
    Am J Manag Care 16:e86-e93. 2010
    ..To estimate direct medical costs among patients with established cardiovascular disease (CVD)...
  25. doi request reprint Medical care costs one year after identification of hyperglycemia below the threshold for diabetes
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Med Care 46:287-92. 2008
    ..To estimate the resource utilization and medical costs of patients with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or both, in a real-world clinical setting...
  26. doi request reprint Patient characteristics and medical care costs associated with hypertriglyceridemia
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Am J Cardiol 107:225-9. 2011
    ..In conclusion, severe hypertriglyceridemia was associated with 33% to 38% greater medical costs per annum, independent of resource-intensive conditions such as cardiovascular disease, heart failure, hypertension, and diabetes...
  27. ncbi request reprint The impact of cardiovascular disease on medical care costs in subjects with and without type 2 diabetes
    Gregory A Nichols
    Center for Health Research, Portland, Oregon 97227 1110, USA
    Diabetes Care 25:482-6. 2002
    ..We examined whether cardiovascular disease (CVD) affects medical care costs differently in subjects with and without diabetes and explored the impact of CVD on costs across the dimensions of age and diabetes duration...
  28. ncbi request reprint Unadjusted and adjusted prevalence of diagnosed depression in type 2 diabetes
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Diabetes Care 26:744-9. 2003
    ..To estimate the prevalence of diagnosed depression in a large population of individuals with type 2 diabetes, compared to a matched control group, and to estimate the extent of depression that is independently associated with diabetes...
  29. pmc Medical care costs associated with progression of diabetic nephropathy
    Gregory A Nichols
    Kaiser Permanente Center forHealth Research, Portland, Oregon, USA
    Diabetes Care 34:2374-8. 2011
    ..To estimate the direct medical costs of hypertensive patients with type 2 diabetes by the level of proteinuria and to evaluate the differences between patients whose nephropathy did and did not progress...
  30. doi request reprint Change in high-density lipoprotein cholesterol and risk of subsequent hospitalization for coronary artery disease or stroke among patients with type 2 diabetes mellitus
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Am J Cardiol 108:1124-8. 2011
    ..In conclusion, our results add to the growing body of evidence that increasing the HDL cholesterol levels might be an important strategy for CVD risk reduction. The prevention of HDL cholesterol decreases could be equally important...
  31. pmc Metabolic syndrome components are associated with future medical costs independent of cardiovascular hospitalization and incident diabetes
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Metab Syndr Relat Disord 9:127-33. 2011
    ..Furthermore, the independent cost contribution of each component alone and in combination with other components is unknown...
  32. ncbi request reprint Functional status before and after diagnosis of Type 2 diabetes
    G A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR 97227 1110, USA
    Diabet Med 21:793-7. 2004
    ..We examined functional health status prior to the diagnosis of Type 2 diabetes, and measured the effect on functional health status of receiving the diagnosis...
  33. doi request reprint Initial nonadherence, primary failure and therapeutic success of metformin monotherapy in clinical practice
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Curr Med Res Opin 26:2127-35. 2010
    ..To document the extent to which drug naïve patients with diabetes continued newly initiated metformin monotherapy, and who subsequently experienced primary failure or therapeutic success...
  34. pmc Cardiovascular disease, heart failure, chronic kidney disease and depression independently increase the risk of incident diabetes
    G A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Avenue, Portland, OR, USA
    Diabetologia 54:523-6. 2011
    ..However, these conditions are often present prior to diabetes diagnosis. We sought to determine whether they increase the risk of developing diabetes independent of other risk factors...
  35. ncbi request reprint The incidence of congestive heart failure in type 2 diabetes: an update
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Diabetes Care 27:1879-84. 2004
    ....
  36. ncbi request reprint Type 2 diabetes: incremental medical care costs during the first 8 years after diagnosis
    J B Brown
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Diabetes Care 22:1116-24. 1999
    ..To describe and analyze the time course of medical care costs caused by type 2 diabetes, from the time of diagnosis through the first 8 postdiagnostic years...
  37. ncbi request reprint Type 2 diabetes: incremental medical care costs during the 8 years preceding diagnosis
    G A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Diabetes Care 23:1654-9. 2000
    ..To describe and analyze medical care costs for the 8 years preceding a diagnosis of type 2 diabetes...
  38. ncbi request reprint Predictors of glycemic control in insulin-using adults with type 2 diabetes
    G A Nichols
    Center for Health Research, Kaiser Permanente Northwest Division, Portland, Oregon 97227 1098, USA
    Diabetes Care 23:273-7. 2000
    ..To determine the characteristics that influence glycemic control among insulin-using adults with type 2 diabetes...
  39. ncbi request reprint Congestive heart failure in type 2 diabetes: prevalence, incidence, and risk factors
    G A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227 1098, USA
    Diabetes Care 24:1614-9. 2001
    ..To estimate the prevalence and incidence of congestive heart failure (CHF) in populations with and without type 2 diabetes and to identify risk factors for diabetes-associated CHF...
  40. pmc Achieving further glycemic control in type 2 diabetes mellitus
    G A Nichols
    Kaiser Permanente Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227, USA
    West J Med 173:175-9. 2000
    ..To identify patients with type 2 diabetes mellitus who were in poor glycemic control and therapeutic adjustments that might improve control...
  41. pmc Case-control study of 10 years of comprehensive diabetes care
    J B Brown
    Center for Health Research, Portland, OR 97227, USA
    West J Med 172:85-90. 2000
    ..To describe the long-term clinical impact of a comprehensive management program instituted throughout a health system for members with diabetes mellitus...
  42. ncbi request reprint Health care costs associated with escalation of drug treatment in type 2 diabetes mellitus
    J B Brown
    Kaiser Permanente Northwest Center for Health Research KPCHR, Portland, OR, USA
    Am J Health Syst Pharm 58:151-7. 2001
    ..The total cost of treating patients with type 2 diabetes mellitus at an HMO increased as antidiabetic therapies escalated...
  43. ncbi request reprint Impact of comorbidities on mortality in managed care patients with CKD
    Christina M Gullion
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1110, USA
    Am J Kidney Dis 48:212-20. 2006
    ..This study examines the impact of comorbidities on mortality risk in a cohort with CKD at 3 levels of progression and a sex- and age-matched comparison group...
  44. ncbi request reprint Contemporary analysis of secondary failure of successful sulfonylurea therapy
    Gregory A Nichols
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1098, USA
    Endocr Pract 13:37-44. 2007
    ..To revise older estimates of secondary failure that may no longer describe the contemporary pattern of sulfonylurea (SU) monotherapy and to identify predictors of such failure...
  45. ncbi request reprint Effects of weight gain on medical care costs
    P J Elmer
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227 1110, USA
    Int J Obes Relat Metab Disord 28:1365-73. 2004
    ..To examine in middle-aged adults the effect of medical care costs of large, rapid weight gain compared to weight maintenance...
  46. pmc Secondary failure of metformin monotherapy in clinical practice
    Jonathan B Brown
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Diabetes Care 33:501-6. 2010
    ..Our findings support the current treatment algorithm for hyperglycemia management that recommends metformin initiation when diabetes is first diagnosed...
  47. ncbi request reprint Controlled trials of CQI and academic detailing to implement a clinical practice guideline for depression
    J B Brown
    Kaiser Permanente Center for Health Research, Portland, Oregon, USA
    Jt Comm J Qual Improv 26:39-54. 2000
    ....
  48. ncbi request reprint Treated prevalence, incidence, and pharmacotherapy of child and adolescent mood disorders in an HMO
    L L DeBar
    Kaiser Permanente Center for Health Research, Portland, Oregon 97227 1110, USA
    Ment Health Serv Res 3:73-89. 2001
    ..S. Department of Health and Human Services, 1993]), that is, primarily with SSRI medications...
  49. ncbi request reprint Older women with fractures: patients falling through the cracks of guideline-recommended osteoporosis screening and treatment
    Adrianne C Feldstein
    Kaiser Permanente Center for Health Research, 3800 North Interstate Avenue, Portland, OR 97227 1110, USA
    J Bone Joint Surg Am 85:2294-302. 2003
    ..Our purpose was to aid in the design of more effective future interventions...
  50. ncbi request reprint Slow response to loss of glycemic control in type 2 diabetes mellitus
    Jonathan B Brown
    Kaiser Permanente Center for Health Research, Portland, Ore 97227 1110, USA
    Am J Manag Care 9:213-7. 2003
    ..To achieve glycemic control in type 2 diabetes mellitus, the American Diabetes Association (ADA) recommends intensification of glucose-lowering therapy when the glycosylated hemoglobin (HbA1c) level exceeds 8.0%...
  51. pmc Weight change and glycemic control after diagnosis of type 2 diabetes
    Adrianne C Feldstein
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227, USA
    J Gen Intern Med 23:1339-45. 2008
    ..Limited community-based data describe weight change after diabetes diagnosis...
  52. ncbi request reprint Use of oral antithrombotic agents among health maintenance organization members with atherosclerotic cardiovascular disease
    Jonathan B Brown
    Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227 1110, USA
    Arch Intern Med 162:193-9. 2002
    ..Although antithrombotic agents are often prescribed at hospital discharge after CVD-related events, much less is known about the ongoing use of such agents...
  53. ncbi request reprint The burden of treatment failure in type 2 diabetes
    Jonathan B Brown
    Kaiser Permanente Center for Health Research, Portland, OR, USA
    Diabetes Care 27:1535-40. 2004
    ..In type 2 diabetes, therapies to maintain blood glucose control usually fail after several years. We estimated the glycemic burden that accumulates from treatment failure and describe the time course and predictors of failure...
  54. ncbi request reprint Effect of a patient panel-support tool on care delivery
    Adrianne C Feldstein
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227, USA
    Am J Manag Care 16:e256-66. 2010
    ..To evaluate the effect of a patient panel-support tool (PST) on care delivery for diabetes mellitus (DM) and cardiovascular disease (CVD)...
  55. doi request reprint Lower visual acuity predicts worse utility values among patients with type 2 diabetes
    David H Smith
    Center for Health Research, Kaiser Permanente Northwest, 3800 N Interstate Ave, Portland, OR 97227, USA
    Qual Life Res 17:1277-84. 2008
    ..We estimated the quality of life impact of vision loss in a community-based population with diabetes...
  56. pmc Weight change in diabetes and glycemic and blood pressure control
    Adrianne C Feldstein
    1Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA
    Diabetes Care 31:1960-5. 2008
    ..Weight loss in type 2 diabetes is undisputedly important, and data from community settings are limited. We evaluated weight change and resulting glycemic and blood pressure control in type 2 diabetic patients at an HMO...
  57. doi request reprint Effectiveness of bisphosphonate therapy in a community setting
    Adrianne C Feldstein
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227, USA
    Bone 44:153-9. 2009
    ..Clinical trials have shown the effectiveness of bisphosphonates, the most commonly prescribed treatments, in reducing fracture risk. The population-based effectiveness of bisphosphonates in clinical practice is uncertain...
  58. ncbi request reprint Practice patterns in patients at risk for glucocorticoid-induced osteoporosis
    Adrianne C Feldstein
    Center for Health Research, Kaiser Permanente Northwest, 3800 N Interstate Avenue, Portland, OR 97227 1110, USA
    Osteoporos Int 16:2168-74. 2005
    ..Future research should focus on understanding barriers to GIOP identification and facilitating osteoporosis management...
  59. ncbi request reprint Following depression in primary care: do family practice physicians ask about depression at different rates than internal medicine physicians?
    G A Nichols
    Kaiser Permanente Center for Health Research, Portland, Ore 97227 1098, USA
    Arch Fam Med 9:478-82. 2000
    ..To determine whether the chronically or recurrently depressed patients of family practice and internal medicine physicians differed in the proportion reporting that their primary care physician asked them about depression symptoms...
  60. ncbi request reprint Understanding changes in primary care clinicians' satisfaction from depression care activities during adoption of selective serotonin reuptake inhibitors
    Diana Shye
    Kaiser Permanente, Center for Health Research, Portland, OR, USA
    Am J Manag Care 8:963-74. 2002
    ..To describe how primary care clinicians' perceptions about depression care as a clinical activity changed during the adoption of selective serotonin reuptake inhibitors (SSRIs) in their health maintenance organization (HMO)...
  61. ncbi request reprint Response to Olivarius and Siersma: weight change or change in weight trend. Differences in analytical approaches (and differences in study samples)
    Gregory A Nichols
    Diabetes Obes Metab 10:183-4. 2008
  62. ncbi request reprint Risk-factor clustering and cardiovascular disease risk in hypertensive patients
    Derek Weycker
    Policy Analysis, Inc, Brookline, Massachusetts 02445, USA
    Am J Hypertens 20:599-607. 2007
    ..Patients with hypertension often have other major risk factors for cardiovascular disease (CVD). Little is known, however, about the extent of risk-factor clustering in these patients and its importance in CVD risk and medical-care costs...
  63. ncbi request reprint Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization
    Douglas S Keith
    Division of Nephrology and Hypertension, Oregon Health and Science University, USA
    Arch Intern Med 164:659-63. 2004
    ..The purpose of this study was to understand the natural history of chronic kidney disease with regard to progression to renal replacement therapy (transplant or dialysis) and death in a representative patient population...

Research Grants1

  1. Characteristics and Costs of Impaired Fasting Glucose
    Gregory Nichols; Fiscal Year: 2005
    ..Finally, we will calculate and compare the costs of medical care for patients in each FPG stage, and estimate multivariate models to identify factors that contribute to medical costs in each stage. ..