Affiliation: Kaiser Permanente
- Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonistParadi Mirmirani
Departments of Dermatology, The Permanente Medical Group, Vallejo, California, USA
Arch Dermatol 145:1363-6. 2009..Treatment typically includes use of antiinflammatory medications; although symptoms may improve,hair loss is often progressive...
- A practical, algorithmic approach to diagnosing hair shaft disordersParadi Mirmirani
Department of Dermatology, Kaiser Permanente Vallejo Medical Center, Vallejo, CA 94589, USA
Int J Dermatol 50:1-12. 2011..We have also included a summary of the molecular defects where known, which can be helpful in providing a correlation with clinical findings, in counseling patients, and potentially offering treatment options...
- The "Fringe Sign" - A useful clinical finding in traction alopecia of the marginal hair lineAman Samrao
Department of Dermatology, University of California, San Francisco, California, USA
Dermatol Online J 17:1. 2011....
- Hormonal changes in menopause: do they contribute to a 'midlife hair crisis' in women?P Mirmirani
Department of Dermatology, The Permanente Medical Group, Vallejo, CA 94589, USA
Br J Dermatol 165:7-11. 2011..Analyses of hair amount using a model of hair density and hair diameters suggest that the impact of changing hair parameters is most notable in the mid-forties for women...
- Epidemiologic trends in pediatric tinea capitis: a population-based study from Kaiser Permanente Northern CaliforniaParadi Mirmirani
Permanente Medical Group, Vallejo, California Case Western Reserve University, Cleveland, Ohio University of California, San Francisco, California Electronic address
J Am Acad Dermatol 69:916-21. 2013..Epidemic levels of tinea capitis (TC) have previously been reported in children...
- Managing hair loss in midlife womenParadi Mirmirani
Department of Dermatology, The Permanente Medical Group, Vallejo, CA 94589, United States
Maturitas 74:119-22. 2013..In this review, management of hair loss in midlife women is discussed with a focus on three most commonly encountered clinical conditions: female pattern hair loss, hair shaft alterations due to hair care, and telogen effluvium...
- Abnormal inner root sheath of the hair follicle in the loose anagen hair syndrome: an ultrastructural studyParadi Mirmirani
Department of Dermatology, The Permanente Medical Group, Vallejo, California, USA
J Am Acad Dermatol 64:129-34. 2011..It first manifests in early childhood when the main concern of parents is that the sparse hair does not grow. The hair density and length improve with age, but the looseness persists into adulthood...
- Pili torti: clinical findings, associated disorders, and new insights into mechanisms of hair twistingParadi Mirmirani
The Permanente Medical Group, Kaiser Permanente Vallejo Medical Center, California 94589, USA
Cutis 84:143-7. 2009..More recent research suggests that these alterations may occur in the face of mitochondrial dysfunction and may be influenced by the presence of reactive oxygen species...
- Tinea capitis mimicking cicatricial alopecia: what host and dermatophyte factors lead to this unusual clinical presentation?Paradi Mirmirani
The Permanente Medical Group, Vallejo, California 94589, USA
J Am Acad Dermatol 60:490-5. 2009..An understanding of the clinical morphology of tinea capitis in the context of both host and fungal factors may improve treatment strategies and direct future paradigms of therapy...
- Hair follicle stem cell-specific PPARgamma deletion causes scarring alopeciaPratima Karnik
Department of Dermatology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
J Invest Dermatol 129:1243-57. 2009..We propose that PPARgamma-targeted therapy may represent a new strategy in the treatment of these disorders...
- Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopeciaSreejith P Panicker
Department of Dermatology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, United States of America
PLoS ONE 7:e38449. 2012....
- Does D matter? The role of vitamin D in hair disorders and hair follicle cyclingKarrie T Amor
Department of Dermatology, University of Texas and MD Anderson Cancer Center, Houston, Texas, USA
Dermatol Online J 16:3. 2010..The role of vitamin D in the proliferation and differentiation of keratinocytes is well known within the field of dermatology...
- Primary cicatricial alopecia: histopathologic findings do not distinguish clinical variantsParadi Mirmirani
University of California, San Francisco, San Francisco, California, USA
J Am Acad Dermatol 52:637-43. 2005..The varied clinical features and differences in terminology have led to difficulties in defining consistent clinicopathologic correlation...
- Elastin staining patterns in primary cicatricial alopeciaMaxwell A Fung
Department of Dermatology, University of California, Davis, Sacramento, California Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, California Electronic address
J Am Acad Dermatol 69:776-82. 2013..Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled...
- Bandlike frontal hair loss in a 62-year-old womanParadi Mirmirani
University of California, San Francisco, USA
Arch Dermatol 139:1363-8. 2003
- Central centrifugal cicatricial alopecia: Superimposed tinea capitis as the etiology of chronic scalp pruritusCharles Chiang
Department of Dermatology, University of California San Francisco, San Francisco, CA, USA
Dermatol Online J 14:3. 2008..The rarity of severe pruritus in CCCA should prompt a search for a fungal infection in these patients...
- Clinical approach to the patient with alopeciaAmy Han
Case Western School of Medicine, Department of Dermatology, Cleveland, OH, USA
Semin Cutan Med Surg 25:11-23. 2006..This review will present a clinical approach to the patient with alopecia by describing the history, clinical findings, and diagnosis of various hair loss disorders...
- Hair depigmentation during chemotherapy with a class III/V receptor tyrosine kinase inhibitorShannon Routhouska
Department of Dermatology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA
Arch Dermatol 142:1477-9. 2006..An interruption of SCF/c-kit signal transduction results in hair depigmentation...
- Short course of oral cyclosporine in lichen planopilarisParadi Mirmirani
Department of Dermatology, University of California San Francisco, CA 94117, USA
J Am Acad Dermatol 49:667-71. 2003..In all 3 patients alleviation of symptoms, resolution of clinical activity, and halting progression of hair loss was achieved in 3 to 5 months with sustained effect at 12 months after a short course of cyclosporine therapy...
- Hair loss remedies--separating fact from fictionIlian Bandaranayake
Department of Dermatology, University Hospitals of Cleveland, Case Western Reserve University, Ohio, USA
Cutis 73:107-14. 2004..We intend for this information to serve as a "consumer report" for healthcare providers and patients and to help separate some of the valid claims for hair regrowth from those that are purely fiction...
- How to approach hair loss in womenParadi Mirmirani
Department of Dermatology, Kaiser Permanente Medical Center, Vallejo, CA, USA
Dermatol Nurs 19:531-5. 2007..Lastly, recommendations for effectively counseling women with hair loss are provided...