Research Topics
| Nicola P KleinSummaryAffiliation: Kaiser Permanente Country: USA Publications
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Detail Information
Publications
Rates of autoimmune diseases in Kaiser Permanente for use in vaccine adverse event safety studiesNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
Vaccine 28:1062-8. 2010..These background incidence rates should prove useful for future observational vaccine safety studies and will help guide evaluation of potential vaccine AID events following introduction of new vaccines...
Safety of quadrivalent human papillomavirus vaccine administered routinely to femalesNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
Arch Pediatr Adolesc Med 166:1140-8. 2012..To assess the safety of the quadrivalent human papillomavirus vaccine (HPV4) in females following routine administration...
Waning protection after fifth dose of acellular pertussis vaccine in childrenNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
N Engl J Med 367:1012-9. 2012..In the United States, children receive five doses of diphtheria, tetanus, and acellular pertussis (DTaP) vaccine before 7 years of age. The duration of protection after five doses of DTaP is unknown...
Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine administered concomitantly with measles, mumps, rubella, varicella vaccine in healthy toddlersNicola P Klein
Kaiser Permanente Vaccine Center, Oakland, CA 94612, USA
Vaccine 30:3929-36. 2012....
Measles-containing vaccines and febrile seizures in children age 4 to 6 yearsNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
Pediatrics 129:809-14. 2012..Among 1- to 2-year-olds, the risk of febrile seizures 7 to 10 days after MMRV is double that after separate MMR + V. Whether MMRV or MMR + V affects risk for febrile seizure risk among 4- to 6-year-olds has not been reported...
Safety and immunogenicity of a novel quadrivalent meningococcal CRM-conjugate vaccine given concomitantly with routine vaccinations in infantsNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
Pediatr Infect Dis J 31:64-71. 2012..In phase II studies, MenACWY-CRM elicited robust immunologic responses in young infants. We now present results from our pivotal phase III infant immunogenicity/safety study...
An open-label, randomized, multi-center study of the immunogenicity and safety of DTaP-IPV (Kinrix™) co-administered with MMR vaccine with or without varicella vaccine in healthy pre-school age childrenNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA, USA
Vaccine 30:668-74. 2012..This study was undertaken to evaluate the immunogenicity and reactogenicity of Kinrix™ when co-administered with MMR (M-M-RII(®), Merck & Co.) and Varivax™ (Merck & Co.) in 4-6 year old children...
Evaluation of immunization rates and safety among children with inborn errors of metabolismNicola P Klein
Kaiser Permanente Vaccine Study Center, 1 Kaiser Plaza, 16th Floor, Oakland, CA 94612, USA
Pediatrics 127:e1139-46. 2011..Children with inherited metabolic disorders are a potential high-risk group for vaccine-preventable diseases, yet information regarding immunization rates and vaccine safety within this population is limited...
Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizuresNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, USA
Pediatrics 126:e1-8. 2010..Now with data on twice as many vaccine recipients, our goal was to reexamine seizure risk after MMRV vaccine...
Post-marketing safety evaluation of a tetanus toxoid, reduced diphtheria toxoid and 3-component acellular pertussis vaccine administered to a cohort of adolescents in a United States health maintenance organizationNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA, USA
Pediatr Infect Dis J 29:613-7. 2010....
Preterm infants' T cell responses to inactivated poliovirus vaccineNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, California 94612, USA
J Infect Dis 201:214-22. 2010..The aim of the present study was to compare the T cell responses of preterm infants after inactivated poliovirus vaccination with those of term infants...
Differential maternal responses to a newly developed vaccine information pamphletNicola P Klein
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, United States
Vaccine 28:323-8. 2009..These data suggest that early provision of tailored immunization material along with the VIS to new mothers may enhance their overall confidence in vaccines and that additional strategies targeted toward certain mothers may be needed...
Risk factors for developing apnea after immunization in the neonatal intensive care unitNicola P Klein
Kaiser Permanente Vaccine Studies Center, 1 Kaiser Plaza, 16th Floor, Oakland, CA 94612, USA
Pediatrics 121:463-9. 2008..Among hospitalized NICU infants, preimmunization apnea is a well-recognized predictor of postimmunization apnea. However, predictors for postimmunization apnea among NICU infants without preimmunization apnea have not been investigated...
A role for genetics in the immune response to the varicella vaccineNicola P Klein
Kaiser Permanente Vaccine Study Center and Division of Research, Oakland, CA 94612, USA
Pediatr Infect Dis J 26:300-5. 2007..A wide range in antibody titers has been found after immunization with the varicella vaccine, although the basis for these differences has not been described...
Epidemiologic and clinical features of Bell's palsy among children in Northern CaliforniaAli Rowhani-Rahbar
Kaiser Permanente Vaccine Study Center, Oakland, Calif 94612, USA
Neuroepidemiology 38:252-8. 2012..Large population-based studies of BP among children are lacking. We determined epidemiologic and clinical features of BP among children enrolled in a large integrated health care delivery system...
Immunization and Bell's palsy in children: a case-centered analysisAli Rowhani-Rahbar
Kaiser Permanente Vaccine Study Center, Oakland, California, USA
Am J Epidemiol 175:878-85. 2012..Similarly, no association was found between vaccines and BP during the periods 1-14 and 29-56 days following immunization. Results of this study suggest that there is no association between immunization and BP in children...
Risk of rheumatoid arthritis following vaccination with tetanus, influenza and hepatitis B vaccines among persons 15-59 years of agePaula Ray
Kaiser Permanente Vaccine Study Center, Oakland, CA, USA
Vaccine 29:6592-7. 2011..Associations between vaccinations, particularly hepatitis B, and onset of rheumatoid arthritis (RA) have been reported, but examined in few large-scale studies...
Surveillance for invasive pneumococcal disease during 2000-2005 in a population of children who received 7-valent pneumococcal conjugate vaccineSteven Black
Division of Pediatric Infectious Diseases, Stanford University School of Medicine, Stanford, CA, USA
Pediatr Infect Dis J 26:771-7. 2007....
Biologically plausible and evidence-based risk intervals in immunization safety researchAli Rowhani-Rahbar
Kaiser Permanente Vaccine Study Center, Oakland, CA 94612, United States
Vaccine 31:271-7. 2012..In addition, we review methodologic issues related to the determination of risk intervals for consideration in future studies of immunization safety...
Diphtheria-tetanus-acellular pertussis and inactivated poliovirus vaccines given separately or combined for booster dosing at 4-6 years of ageSteven Black
Stanford University, Palo Alto, CA, USA
Pediatr Infect Dis J 27:341-6. 2008..A combined DTaP-IPV vaccine is being developed, which would reduce by one the number of injections in this age group...
Recurrent Guillain-Barre syndrome following vaccinationRoger Baxter
Kaiser Permanente Vaccine Study Center, Oakland, California 94612, USA
Clin Infect Dis 54:800-4. 2012....
Assessing the safety of influenza vaccination in specific populations: children and the elderlyAli Rowhani-Rahbar
Kaiser Permanente Vaccine Study Center, One Kaiser Plaza, Floor 16, Oakland, CA 94612, USA
Expert Rev Vaccines 11:973-84. 2012..The authors discuss the current status of the field, particularly the use of new technologies for influenza vaccines and their potential safety profile...
Safety of trivalent inactivated influenza vaccine in children aged 24 to 59 months in the vaccine safety datalinkJason M Glanz
Institute for Health Research, Kaiser Permanente Colorado, Denver, CO 80237 8066, USA
Arch Pediatr Adolesc Med 165:749-55. 2011....
Clinical assessment of serious adverse events in children receiving 2009 H1N1 vaccinationBarbara A Pahud
Division of Pediatric Infectious Diseases, Stanford University Medical Center, Stanford, CA, USA
Pediatr Infect Dis J 32:163-8. 2013..Monovalent 2009 H1N1 influenza vaccines were licensed and administered in the United States during the H1N1 influenza pandemic between 2009 and 2013...
Variability and gender differences in memory T cell immunity to varicella-zoster virus in healthy adultsNicola P Klein
Division of Pediatric Infectious Diseases, Stanford University School of Medicine, Stanford, CA 94305 520, USA
Vaccine 24:5913-8. 2006..Taken together, results suggest that further studies regarding immunization of younger adults and females with the modified, high-potency live attenuated VZV vaccine may be warranted...
