Teresa A Hillier

..To determine whether adults diagnosed with type 2 diabetes at 18-44 years of age (early type 2 diabetes) have different metabolic profiles at diagnosis than adults diagnosed at > or =45 years of age (usual type 2 diabetes)...

..Whether repeat bone mineral density (BMD) measurement adds benefit beyond the initial BMD measurement in predicting fractures in older women is unknown...

..To determine whether adults diagnosed with type 2 diabetes from age 18 to 44 years more aggressively develop clinical complications after diagnosis than adults diagnosed at >or=45 years of age...

..Fractures have been associated with subsequent increases in mortality, but it is unknown how long that increase persists...

..The study compares the risk of incident diabetes associated with fasting plasma glucose levels in the normal range, controlling for other risk factors...

..To estimate gestational diabetes mellitus (GDM) prevalence and hyperglycemia in a large multi-ethnic population and evaluate the differences in glucose measures by age and ethnicity...

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..The FRAX and simpler models predict 10-year risk of incident hip and major osteoporotic fractures in older US women with normal or low bone mass...

..Height loss >5 cm (2″) in older women was associated with a nearly 50% increased risk of hip fracture, nonspine fracture, and mortality-independent of incident VFx and BMD...

..To estimate how maternal weight gain and maternal glucose relate to fetal macrosomia risk (greater than 4,000 g) among a population universally screened for gestational diabetes mellitus (GDM)...

..25-Hydroxyvitamin D [25(OH)D] levels are lower in obese individuals. Determining whether low vitamin D status can predispose weight gain requires a longitudinal study...

..We sought to estimate the rate of progression from newly acquired (incident) impaired fasting glucose (IFG) to diabetes under the old and new IFG criteria and to identify predictors of progression to diabetes...

..These findings call attention to the many older women who suffer hip fracture but do not have particularly low antecedent BMD measures and help begin to identify risk factors associated with higher bone density levels...

..In conclusion, childbearing reduces hip fracture risk by means that may be independent of hip bone mineral density...

..To determine whether poorer visual acuity and contrast sensitivity are independent risk factors for all-cause and traumatic mortality in older women...

..In 2003, the U.S. Preventive Services Task Force concluded that evidence was insufficient to advise for or against routinely screening all pregnant women for gestational diabetes mellitus...

..The purpose of this study was to determine how the range of measured maternal glycemia in pregnancy relates to risk of obesity in childhood...

..Women with low bone mineral density (BMD) and prevalent vertebral fractures have a greater risk of incident vertebral fractures over the short-term, but their absolute risk of vertebral fracture over the long-term is uncertain...

..We performed a prospective cohort study to examine the relationship among thyroid hormone use, previous hyperthyroidism, abnormal thyroid function, and mortality...

..Risk factors and low BMD should be useful to help focus efforts to prevent these fractures...

..To determine whether older women with diabetes have an increased risk of falls and whether known risk factors for falls account for any increased risk...

..8-2.9). The authors suggest that obesity alone--and particularly when the MS is present--increases CHD risk in patients with T2DM. High levels of high-density lipoprotein may modify this relationship...

..The "accelerator hypothesis" predicts that fatness is associated with an earlier age at onset of type 1 diabetes. We tested the hypothesis using data from the SEARCH for Diabetes in Youth study...

..To devise, validate, and test a software model that improves how clinicians calculate individual risk for osteoporotic fracture and expected treatment benefit...

..This study investigated the association between BMI and mortality after breast cancer diagnosis in a cohort of older Caucasian women enrolled in the Study of Osteoporotic Fractures...

..To test the association between self-reported sleep and nap habits and risk of falls and fractures in a large cohort of older women...

..To test the hypothesis that use of lipid-lowering drugs reduces the risk of breast cancer in older women...

..Variation at the IL-6 locus may contribute to the genetic susceptibility to bone fragility...

..Validation of such an approach would require intervention trials in patients with prior wrist fracture...

..To determine whether changes in hip bone mineral density (BMD) differ in Caucasian and African American women...

..The high frequency of this variant confers a population attributable risk that is similar to several established risk factors for fracture...

..07, 2.45; p trend = 0.014) compared with women with lowest lead level. Blood lead levels are associated with an increased risk of falls and fractures, extending the negative health consequences of lead to include osteoporotic fractures...

..02). The MMP2 rs2287074 A allele may be associated with a lower likelihood of ARM in older Caucasian women, particularly those who have never used hormone therapy. The role of MMP2 rs2287074 in ARM should be further elucidated...

..Frailty, as defined by the index derived from the Cardiovascular Health Study (CHS index), predicts risk of adverse outcomes in older adults. Use of this index, however, is impractical in clinical practice...

..To determine whether bone mineral density (BMD) is associated with age-related maculopathy (ARM) risk in older women...

..It is widely believed that fractures resulting from high trauma are not osteoporotic; however, this assumption has not been studied prospectively...

..13; 95% CI, 1.04-1.22) (p for interaction = 0.032). Pre-existing hypertension in women is associated with a greater impact of stroke on cognitive function, possibly by influencing the ability to tolerate or recover from brain injury...