Dina N Greene

Summary

Affiliation: Kaiser Permanente
Country: USA

Publications

  1. doi request reprint Performance characteristics of the Beckman Coulter total βhCG (5th IS) assay
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States Electronic address
    Clin Chim Acta 439:61-7. 2015
  2. doi request reprint Advances in detection of hemoglobinopathies
    Dina N Greene
    TPMG, Northern California Kaiser Permanente Regional Laboratories, Berkeley, CA, United States Electronic address
    Clin Chim Acta 439:50-7. 2015
  3. doi request reprint Neonatal total bilirubin measurements: Still room for harmonization
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, USA Electronic address
    Clin Biochem 47:1112-5. 2014
  4. doi request reprint Facilitating the laboratory diagnosis of α1-antitrypsin deficiency
    Dina N Greene
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Am J Clin Pathol 139:184-91. 2013
  5. doi request reprint Limitations in qualitative point of care hCG tests for detecting early pregnancy
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States
    Clin Chim Acta 415:317-21. 2013
  6. doi request reprint Comparison of Sebia Capillarys Flex capillary electrophoresis with the BioRad Variant II high pressure liquid chromatography in the evaluation of hemoglobinopathies
    Dina N Greene
    The Permanente Medical Group Regional Laboratories, Kaiser Permanente Northern California, Berkeley, CA, United States
    Clin Chim Acta 413:1232-8. 2012
  7. doi request reprint Human chorionic gonadotropin discriminatory zone in ectopic pregnancy: does assay harmonization matter?
    Diana Desai
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah
    Fertil Steril 101:1671-4. 2014
  8. doi request reprint Identification of one or two α-globin gene deletions by isoelectric focusing electrophoresis
    Archana M Agarwal
    Department of Pathology, University of Utah Health Sciences, Salt Lake City, UT, USA
    Am J Clin Pathol 140:301-5. 2013
  9. doi request reprint α1-Antitrypsin phenotypes and associated serum protein concentrations in a large clinical population
    Joshua A Bornhorst
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Chest 143:1000-8. 2013
  10. doi request reprint α1-antitrypsin deficiency in fraternal twins born with familial spontaneous pneumothorax
    Dina N Greene
    Department of Pathology, University of Utah School of Medicine, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Chest 141:239-41. 2012

Collaborators

Detail Information

Publications20

  1. doi request reprint Performance characteristics of the Beckman Coulter total βhCG (5th IS) assay
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States Electronic address
    Clin Chim Acta 439:61-7. 2015
    ..Beckman Coulter recently released the first commercially available hCG reagent calibrated against the 5th International Standard (IS) for hCG (total βhCG (5th IS)). We performed a comprehensive analytical validation of this reagent...
  2. doi request reprint Advances in detection of hemoglobinopathies
    Dina N Greene
    TPMG, Northern California Kaiser Permanente Regional Laboratories, Berkeley, CA, United States Electronic address
    Clin Chim Acta 439:50-7. 2015
    ..This review provides an overview of the current hemoglobin analysis techniques, and also discusses technologies that have potential to translate into widespread clinical settings. ..
  3. doi request reprint Neonatal total bilirubin measurements: Still room for harmonization
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, USA Electronic address
    Clin Biochem 47:1112-5. 2014
    ..A recent recalibration of the only commercially available "dry" chemistry assay was issued to reduce these differences. This study evaluated the post-recalibration bias between the two assay types...
  4. doi request reprint Facilitating the laboratory diagnosis of α1-antitrypsin deficiency
    Dina N Greene
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Am J Clin Pathol 139:184-91. 2013
    ..In conclusion, a reference compendium of known AAT phenotypes was established that can serve as a resource for interpreting AAT phenotypes...
  5. doi request reprint Limitations in qualitative point of care hCG tests for detecting early pregnancy
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States
    Clin Chim Acta 415:317-21. 2013
    ..Qualitative point-of-care (POC) human chorionic gonadotropin (hCG) testing is often used. There is a gap in the literature for evaluating patient samples with low (<300 IU/l) hCG concentration using POC devices...
  6. doi request reprint Comparison of Sebia Capillarys Flex capillary electrophoresis with the BioRad Variant II high pressure liquid chromatography in the evaluation of hemoglobinopathies
    Dina N Greene
    The Permanente Medical Group Regional Laboratories, Kaiser Permanente Northern California, Berkeley, CA, United States
    Clin Chim Acta 413:1232-8. 2012
    ..Here we compare a new instrument, the Sebia Capillarys Flex (capillary zone electrophoresis (CE)), with the BioRad Variant II (high pressure liquid chromatography (HPLC) in the evaluation of hemoglobinopathies...
  7. doi request reprint Human chorionic gonadotropin discriminatory zone in ectopic pregnancy: does assay harmonization matter?
    Diana Desai
    Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah
    Fertil Steril 101:1671-4. 2014
    ..To determine the effect that lack of hCG assay harmonization has on the interpretation of a serum hCG concentration with regards to the hCG discriminatory zone...
  8. doi request reprint Identification of one or two α-globin gene deletions by isoelectric focusing electrophoresis
    Archana M Agarwal
    Department of Pathology, University of Utah Health Sciences, Salt Lake City, UT, USA
    Am J Clin Pathol 140:301-5. 2013
    ..To investigate the utility of isoelectric focusing electrophoresis (IEF) for identifying patients with α-thalassemia, which results from the deletion of 1 or more of the α-globin genes...
  9. doi request reprint α1-Antitrypsin phenotypes and associated serum protein concentrations in a large clinical population
    Joshua A Bornhorst
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Chest 143:1000-8. 2013
    ..Relative frequencies of rare AAT variant phenotypes (non-M, Z, and S) and associated serum concentrations in the clinical population have not been thoroughly described...
  10. doi request reprint α1-antitrypsin deficiency in fraternal twins born with familial spontaneous pneumothorax
    Dina N Greene
    Department of Pathology, University of Utah School of Medicine, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    Chest 141:239-41. 2012
    ..These findings suggest a role for AAT deficiency in spontaneous pneumothorax of the newborn. To our knowledge, these are the first genetic data to support etiology of neonatal spontaneous familial pneumothorax...
  11. doi request reprint Challenges in harmonizing integrated healthcare network laboratories: Multi-center evaluation of the AccuTnI+3 troponin assay
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, USA Electronic address
    Clin Biochem 48:268-74. 2015
    ..Clinical laboratories are required to validate method performance before testing and reporting patient results...
  12. doi request reprint Development of an equation to correct for hemolysis in direct bilirubin measurements
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States
    Clin Chim Acta 429:194-7. 2014
    ..Package inserts suggest that hemolysis decreases direct bilirubin measurements, but no published studies have adequately described the extent of interference...
  13. doi request reprint A mathematical procedure to estimate the impact of a change in method on discordance or misclassification at a decision limit in laboratory method comparison studies
    Robert L Schmidt
    Department of Pathology and ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, UT, United States Electronic address
    Clin Chim Acta 440:23-30. 2015
    ..Laboratories often adopt new methods. It would be useful to have a statistical procedure to estimate the incremental impact of a change in assay...
  14. doi request reprint Falsely decreased human chorionic gonadotropin (hCG) results due to increased concentrations of the free beta subunit and the beta core fragment in quantitative hCG assays
    David G Grenache
    University of Utah Health Sciences Center, Department of Pathology, Salt Lake City, UT, USA
    Clin Chem 56:1839-44. 2010
    ..The objective of this study was to determine if increased concentrations of hCGβ and hCGβ core fragment (hCGβcf) cause falsely decreased results on 9 commercially available quantitative hCG assays...
  15. doi request reprint Analytical sensitivity of four commonly used hCG point of care devices
    Sandy M Kamer
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, USA
    Clin Biochem 48:448-52. 2015
    ..There are very few studies in the literature that seek to verify the claimed analytical sensitivity of hCG POC devices...
  16. doi request reprint Age, sex, and racial influences on the Beckman Coulter AccuTnI+3 99th percentile
    Dina N Greene
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States Electronic address
    Clin Chim Acta 444:149-53. 2015
    ..We validated the stated 99th percentile (20ng/l) using a large population of healthy adults representative of the Northern California population...
  17. doi request reprint Performance specifications of common chemistry analytes on the AU series of chemistry analyzers for miscellaneous body fluids
    Maun Jan Lin
    Kaiser Permanente, TPMG Northern California Regional Laboratory, Berkeley, CA, United States Electronic address
    Clin Chim Acta 426:121-6. 2013
    ..Standard chemistry analyzers are generally not FDA approved for body fluid analysis and regulatory authorities require individual laboratories to validate their performance characteristics...
  18. doi request reprint Misclassification of an apparent alpha 1-antitrypsin "Z" deficiency variant by melting analysis
    Dina N Greene
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Clin Chim Acta 412:1454-6. 2011
    ..AAT deficiency is diagnosed using a combination of genetic and biochemical tests. Here we demonstrate how polymorphisms in the AAT gene can lead to genotype/phenotype discrepancies in common AAT assays...
  19. doi request reprint Cerebrospinal fluid myelin basic protein is frequently ordered but has little value: a test utilization study
    Dina N Greene
    The Permanente Medical Group Regional Laboratories, Berkeley, CA, USA
    Am J Clin Pathol 138:262-72. 2012
    ..Importantly, MBP does not add a statistically significant increase in diagnostic sensitivity or specificity when used in combination with OCB and/or IgG index. The data indicate that MBP is an unnecessary and overused test...
  20. ncbi request reprint Evaluation of the integrated E-Z split key(®) cup II for rapid detection of twelve drug classes in urine
    Dina N Greene
    University of Utah Health Sciences Center, Department of Pathology, Salt Lake City, UT 84108, USA
    J Anal Toxicol 35:46-53. 2011
    ..One false-negative result for barbiturates was observed, but was resolved. Overall, the cups demonstrated excellent sensitivity, specificity, and diagnostic efficiency for all drugs represented...