Alan S Go

Summary

Affiliation: Kaiser Permanente
Country: USA

Publications

  1. pmc Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
  2. pmc Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD
    Joshua W Knowles
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Building, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    BMC Med Genet 9:23. 2008
  3. pmc Accounting for the mortality benefit of drug-eluting stents in percutaneous coronary intervention: a comparison of methods in a retrospective cohort study
    Robert W Yeh
    Cardiology Division, GRB800, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    BMC Med 9:78. 2011
  4. pmc Racial variation in lipoprotein-associated phospholipase A₂ in older adults
    Keane K Lee
    Department of Health Research and Policy, Stanford University School of Medicine, HRP Redwood Building, Stanford, CA 94305 5405, USA
    BMC Cardiovasc Disord 11:38. 2011
  5. doi Stroke prevention in atrial fibrillation: another step sideways
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612, USA
    Lancet 371:278-80. 2008
  6. ncbi The epidemiology of atrial fibrillation in elderly persons: the tip of the iceberg
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway Street, 3rd Floor, Oakland, CA 94612, USA
    Am J Geriatr Cardiol 14:56-61. 2005
  7. pmc The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
  8. doi The Cardiovascular Research Network: a new paradigm for cardiovascular quality and outcomes research
    Alan S Go
    Kaiser Permanente Northern California, University of California, San Francisco, Calif, USA
    Circ Cardiovasc Qual Outcomes 1:138-47. 2008
  9. ncbi Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, California 94612 2304, USA
    Circulation 113:2713-23. 2006
  10. ncbi Epidemiology of non-dialysis-requiring chronic kidney disease and cardiovascular disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    Curr Opin Nephrol Hypertens 15:296-302. 2006

Collaborators

Detail Information

Publications108 found, 100 shown here

  1. pmc Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
    ..To focus on African ancestry, we reduced the data to include only those genotypes in each African American determined statistically to be African in origin...
  2. pmc Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD
    Joshua W Knowles
    Division of Cardiovascular Medicine, Falk Cardiovascular Research Building, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    BMC Med Genet 9:23. 2008
    ..We tested whether single nucleotide polymorphisms (SNPs) in OLR1 are associated with clinically significant CAD in the Atherosclerotic Disease, VAscular FuNction, & Geneti C Epidemiology (ADVANCE) study...
  3. pmc Accounting for the mortality benefit of drug-eluting stents in percutaneous coronary intervention: a comparison of methods in a retrospective cohort study
    Robert W Yeh
    Cardiology Division, GRB800, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    BMC Med 9:78. 2011
    ..In order to explore reasons for this discrepancy, we compared outcomes after percutaneous coronary intervention (PCI) with DES or BMS by multiple statistical methods...
  4. pmc Racial variation in lipoprotein-associated phospholipase A₂ in older adults
    Keane K Lee
    Department of Health Research and Policy, Stanford University School of Medicine, HRP Redwood Building, Stanford, CA 94305 5405, USA
    BMC Cardiovasc Disord 11:38. 2011
    ..Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a predictor of cardiovascular events that has been shown to vary with race. The objective of this study was to examine factors associated with this racial variation...
  5. doi Stroke prevention in atrial fibrillation: another step sideways
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612, USA
    Lancet 371:278-80. 2008
  6. ncbi The epidemiology of atrial fibrillation in elderly persons: the tip of the iceberg
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway Street, 3rd Floor, Oakland, CA 94612, USA
    Am J Geriatr Cardiol 14:56-61. 2005
    ....
  7. pmc The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods
    Alan S Go
    Kaiser Permanente Northern California, Oakland, CA, USA
    BMC Nephrol 11:22. 2010
    ..Previous studies on hospital-acquired AKI have important methodological limitations, especially their retrospective study designs and limited ability to control for potential confounding factors...
  8. doi The Cardiovascular Research Network: a new paradigm for cardiovascular quality and outcomes research
    Alan S Go
    Kaiser Permanente Northern California, University of California, San Francisco, Calif, USA
    Circ Cardiovasc Qual Outcomes 1:138-47. 2008
    ..More robust data are also needed on how well clinical trials are translated into contemporary community practice and the associated resource use, costs, and outcomes...
  9. ncbi Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, California 94612 2304, USA
    Circulation 113:2713-23. 2006
    ..It is unclear, however, whether this relation is explained by underlying kidney disease, treatment differences, or associated comorbidity...
  10. ncbi Epidemiology of non-dialysis-requiring chronic kidney disease and cardiovascular disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    Curr Opin Nephrol Hypertens 15:296-302. 2006
    ..To review recent literature about the relationship between non-dialysis-requiring chronic kidney disease and cardiovascular disease as well as possible explanatory factors...
  11. ncbi Antithrombotic therapy for stroke prevention in atrial fibrillation
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, CA 94612 2304, USA
    Prog Cardiovasc Dis 48:108-24. 2005
    ....
  12. ncbi Anticoagulants for stroke prevention in atrial fibrillation: what is the right rate and where do we go from here?
    Alan S Go
    Kaiser Permanente of Northern California, Oakland, CA, USA
    Nat Clin Pract Cardiovasc Med 2:226-7. 2005
  13. pmc Chronic kidney disease and risk for presenting with acute myocardial infarction versus stable exertional angina in adults with coronary heart disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway Street, Oakland, CA 94612 2304, USA
    J Am Coll Cardiol 58:1600-7. 2011
    ..The aim of this study was to examine whether kidney dysfunction is associated with the type of clinical presentation of coronary heart disease (CHD)...
  14. ncbi Statin therapy and risks for death and hospitalization in chronic heart failure
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland 94612, USA
    JAMA 296:2105-11. 2006
    ..Whether statin therapy has beneficial effects on clinical outcomes in patients with heart failure is unclear...
  15. ncbi Factor V Leiden and risk of ischemic stroke in nonvalvular atrial fibrillation: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA, USA
    J Thromb Thrombolysis 15:41-6. 2003
    ..Since atrial and venous pressures are similar, genetic variants that promote venous thromboembolism may increase the risk of atrial thrombi and subsequent stroke in atrial fibrillation...
  16. ncbi Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trials translate into clinical practice?
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612, USA
    JAMA 290:2685-92. 2003
    ..Warfarin has been shown to be highly efficacious for preventing thromboembolism in atrial fibrillation in randomized trials, but its effectiveness and safety in clinical practice is less clear...
  17. ncbi Comparative effectiveness of beta-adrenergic antagonists (atenolol, metoprolol tartrate, carvedilol) on the risk of rehospitalization in adults with heart failure
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, California, USA
    Am J Cardiol 100:690-6. 2007
    ....
  18. pmc Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, CA 94612, USA
    Circulation 119:1363-9. 2009
    ..Existing risk stratification schemes have limited predictive ability. Chronic kidney disease is a major cardiovascular risk factor, but whether it independently increases the risk for ischemic stroke in persons with AF is unknown...
  19. ncbi Statin and beta-blocker therapy and the initial presentation of coronary heart disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, California 94612 2304, USA
    Ann Intern Med 144:229-38. 2006
    ..Patients who present with unstable coronary disease, such as acute myocardial infarction, may systematically differ from patients who present with relatively stable coronary disease, such as exertional angina...
  20. doi Comparative effectiveness of different beta-adrenergic antagonists on mortality among adults with heart failure in clinical practice
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    Arch Intern Med 168:2415-21. 2008
    ..Randomized trials have demonstrated the efficacy of selected beta-blockers in systolic heart failure, but the comparative effectiveness of different beta-blockers in practice is poorly understood...
  21. ncbi Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    N Engl J Med 351:1296-305. 2004
    ..End-stage renal disease substantially increases the risks of death, cardiovascular disease, and use of specialized health care, but the effects of less severe kidney dysfunction on these outcomes are less well defined...
  22. doi Insulin resistance independently predicts the progression of coronary artery calcification
    Keane K Lee
    Stanford University School of Medicine, Stanford, CA, USA
    Am Heart J 157:939-45. 2009
    ..Change in coronary artery calcification is a surrogate marker of subclinical coronary artery disease (CAD). In the only large prospective study, CAD risk factors predicted progression of coronary artery calcium (CAC)...
  23. pmc Ethnic differences in anemia among patients with diabetes mellitus: the Diabetes Study of Northern California (DISTANCE)
    Ameena T Ahmed
    Division of Research, Kaiser Permanente, 2000 Broadway, Oakland, CA 94612, USA
    Am J Hematol 85:57-61. 2010
    ..Blacks with diabetes are at increased risk of anemia relative to whites. These differences may account for some of the observed ethnic disparities in diabetes complications...
  24. pmc Risk factors for end-stage renal disease: 25-year follow-up
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0532, USA
    Arch Intern Med 169:342-50. 2009
    ..Few cohort studies have focused on risk factors for end-stage renal disease (ESRD). This investigation evaluated the prognostic value of several potential novel risk factors for ESRD after considering established risk factors...
  25. pmc Death and disability from warfarin-associated intracranial and extracranial hemorrhages
    Margaret C Fang
    The Department of Medicine, Hospitalist Group, University of California, San Francisco, Calif 94143, USA
    Am J Med 120:700-5. 2007
    ..We examined the rates of death and disability resulting from warfarin-associated intracranial and extracranial hemorrhages in a large cohort of patients with atrial fibrillation...
  26. pmc Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
    Lowell J Lo
    Department of Medicine, University of California, San Francisco, 94143 0532, USA
    Kidney Int 76:893-9. 2009
    ....
  27. ncbi Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation
    Margaret C Fang
    Division of General Internal Medicine, Hospitalist Group, University of California, San Francisco, San Francisco 94143, USA
    Ann Intern Med 141:745-52. 2004
    ..However, higher intensities increase hemorrhage risk. Optimal use of warfarin for atrial fibrillation requires precise information on the risk for intracranial hemorrhage as a function of patient age and anticoagulation intensity...
  28. pmc Gender differences in the risk of ischemic stroke and peripheral embolism in atrial fibrillation: the AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA) study
    Margaret C Fang
    University of California, San Francisco, CA 94143, USA
    Circulation 112:1687-91. 2005
    ..We examined data from a large contemporary cohort of AF patients to address this question...
  29. pmc Incident atrial fibrillation and risk of end-stage renal disease in adults with chronic kidney disease
    Nisha Bansal
    Division of Nephrology, Department of Medicine, University of California, San Francisco, 521 Parnassus Ave, Box 0532, San Francisco, CA 94143, USA
    Circulation 127:569-74. 2013
    ..In this study, we determined the association between incident AF and risk of end-stage renal disease (ESRD) among adults with CKD...
  30. pmc Thirty-day mortality after ischemic stroke and intracranial hemorrhage in patients with atrial fibrillation on and off anticoagulants
    Margaret C Fang
    Department of Medicine, University of California, San Francisco, 505 Parnassus Avenue, Box 0131, San Francisco, CA 94143, USA
    Stroke 43:1795-9. 2012
    ..We assessed the impact of anticoagulation on 30-day mortality from ischemic stroke versus ICH in a large community-based cohort of patients with atrial fibrillation...
  31. pmc Nonrecovery of kidney function and death after acute on chronic renal failure
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 4:891-8. 2009
    ..Relatively little is known about clinical outcomes, especially long-term outcomes, among patients who have chronic kidney disease (CKD) and experience superimposed acute renal failure (ARF; acute on chronic renal failure)...
  32. ncbi Plasma leptin levels and coronary artery calcification in older adults
    Carlos Iribarren
    Kaiser Permanente, Division of Research, 2000 Broadway, Oakland, California 94612, USA
    J Clin Endocrinol Metab 92:729-32. 2007
    ..Leptin is associated with adiposity and insulin resistance and may play a direct role in vascular calcification. It is unclear, however, whether leptin is an independent predictor of atherosclerotic burden...
  33. pmc Warfarin discontinuation after starting warfarin for atrial fibrillation
    Margaret C Fang
    Department of Medicine, University of California, San Francisco, 94143, USA
    Circ Cardiovasc Qual Outcomes 3:624-31. 2010
    ..The objective of this study was to describe factors associated with warfarin discontinuation in patients newly starting warfarin for atrial fibrillation...
  34. pmc A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study
    Margaret C Fang
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    J Am Coll Cardiol 58:395-401. 2011
    ..The purpose of this study was to develop a risk stratification score to predict warfarin-associated hemorrhage...
  35. doi Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC)
    Ruth F Dubin
    San Francisco VA Medical Center, University of California San Francisco, 4150 Clement Street, Box 111A1, San Francisco, CA 94121, USA
    BMC Nephrol 14:229. 2013
    ..We sought to determine the distribution and predictors of hs-TnT in CKD patients without overt cardiovascular disease (CVD)...
  36. pmc A longitudinal study of left ventricular function and structure from CKD to ESRD: the CRIC study
    Nisha Bansal
    Division of Nephrology, University of California, San Francisco, 521 Parnassus Avenue, Box 0532, San Francisco, CA 94143, USA
    Clin J Am Soc Nephrol 8:355-62. 2013
    ..A better understanding of changes in left ventricular mass and ejection fraction during the transition from CKD to ESRD may provide important insights to opportunities to improve cardiac outcomes...
  37. pmc Association of cardiac troponin T with left ventricular structure and function in CKD
    Rakesh K Mishra
    University of California, San Francisco, CA, USA
    Am J Kidney Dis 61:701-9. 2013
    ..We evaluated associations of cTnT levels with cardiac structural and functional abnormalities in a cohort of patients with chronic kidney disease (CKD) without heart failure...
  38. doi Incidental findings on cardiac multidetector row computed tomography among healthy older adults: prevalence and clinical correlates
    Jeremy R Burt
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Arch Intern Med 168:756-61. 2008
    ..Our objectives were to evaluate the prevalence of incidental findings discovered during cardiac MDCT scanning and to identify clinical variables associated with incidental findings...
  39. ncbi Ethnic differences in coronary artery calcium in a healthy cohort aged 60 to 69 years
    Joan M Fair
    Stanford Prevention Research Center, Stanford University, Department of Radiology, Stanford, California, USA
    Am J Cardiol 100:981-5. 2007
    ..In conclusion, our data indicate that the presence of CAC varied significantly across selected race/ethnic groups independent of traditional cardiovascular risk factors...
  40. ncbi Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Arch Intern Med 165:923-8. 2005
    ..Previous cohort studies of the relationship between blood pressure and ESRD did not uniformly screen out baseline kidney disease...
  41. doi Incidental pulmonary nodules on cardiac computed tomography: prognosis and use
    Carlos Iribarren
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612, USA
    Am J Med 121:989-96. 2008
    ..Small asymptomatic lung nodules are found frequently in the course of cardiac computed tomography (CT) scanning. However, the utility of assessing and reporting incidental findings in healthy, asymptomatic subjects is unknown...
  42. ncbi Breast vascular calcification and risk of coronary heart disease, stroke, and heart failure
    Carlos Iribarren
    Kaiser Permanente of Northern California Division of Research, Oakland, California 94612, USA
    J Womens Health (Larchmt) 13:381-9; discussion 390-2. 2004
    ..Vascular calcification holds promise as a useful cardiovascular risk maker. Our objective was to examine the association between breast vascular calcification and risk of cardiovascular disease (CVD) outcomes...
  43. ncbi Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome
    Joan C Lo
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway Street, 2nd Floor, Oakland, CA 94612 2304, USA
    J Clin Endocrinol Metab 91:1357-63. 2006
    ..Polycystic ovary syndrome (PCOS) is associated with menstrual and reproductive abnormalities, insulin resistance, and obesity...
  44. pmc Right coronary wall CMR in the older asymptomatic advance cohort: positive remodeling and associations with type 2 diabetes and coronary calcium
    Masahiro Terashima
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA
    J Cardiovasc Magn Reson 12:75. 2010
    ..The purpose of the study was to evaluate coronary wall CMR in an asymptomatic older cohort...
  45. pmc Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Am J Kidney Dis 58:519-26. 2011
    ..Although individuals with chronic kidney disease (CKD) are at markedly increased mortality risk, the incidence, prevalence, and prognosis of CAC in CKD are not well understood...
  46. ncbi Exploring secular trends in the likelihood of receiving treatment for end-stage renal disease
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 2:81-8. 2007
    ..This trend was not accounted for by increasing prevalence of baseline CKD or risk factors for renal failure. These findings should spur further research into other forces that drive the rise in treated ESRD...
  47. pmc Ethnic differences in the development of albuminuria: the DISTANCE study
    Andy I Choi
    Kaiser Permanente, Division of Research, Oakland, CA 94612, USA
    Am J Manag Care 17:737-45. 2011
    ..To determine whether ethnic differences in the incidence of albuminuria are present in patients with diabetes, and to identify social, behavioral, and provider factors that explain ethnic differences...
  48. ncbi Value of the sagittal abdominal diameter in coronary heart disease risk assessment: cohort study in a large, multiethnic population
    Carlos Iribarren
    Division of Research, Kaiser Permanente of Northern California, Oakland 94612, and Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco General Hospital, CA, USA
    Am J Epidemiol 164:1150-9. 2006
    ..In conclusion, standing sagittal abdominal diameter was a strong predictor of CHD independently of BMI and added incremental CHD risk prediction at each level of BMI...
  49. ncbi Gender and risk of adverse outcomes in heart failure
    Wendy Y Lee
    Division of Research, Kaiser Permanente of Northern California, Oakland, California 94612 2304, USA
    Am J Cardiol 94:1147-52. 2004
    ..71 to 1.11). Among a contemporary, diverse population of patients who had CHF, rates of readmission overall and for CHF remained high, but gender was not independently associated with a differential risk of readmission...
  50. doi Detection of atrial fibrillation after stroke and the risk of recurrent stroke
    Hooman Kamel
    Department of Neurology, University of California San Francisco, San Francisco, California, USA
    J Stroke Cerebrovasc Dis 21:726-31. 2012
    ..These findings identify a subset of patients at high risk for recurrent stroke and highlight the importance of timely detection of AF in patients with stroke...
  51. doi Association of N-terminal pro-B-type natriuretic peptide with left ventricular structure and function in chronic kidney disease (from the Chronic Renal Insufficiency Cohort [CRIC])
    Rakesh K Mishra
    University of California, San Francisco, USA
    Am J Cardiol 111:432-8. 2013
    ..10, 95% CI 0.10 to 0.11; p = 0.07). In conclusion, in this large chronic kidney disease cohort without heart failure, NT-proBNP had strong associations with prevalent LVH and LV systolic dysfunction...
  52. pmc Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: a cohort study
    Nisha Bansal
    Department of Medicine, University of California San Francisco, CA, USA
    BMC Nephrol 12:44. 2011
    ..It is unclear whether differential cardiovascular drug use explains, in part, the excess risk of cardiovascular events and death in patients with CKD and coronary heart disease (CHD)...
  53. doi Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation
    James V Freeman
    Stanford University School of Medicine, California, USA
    Ann Intern Med 154:1-11. 2011
    ..Dabigatran is a fixed-dose, oral direct thrombin inhibitor with similar or reduced rates of ischemic stroke and intracranial hemorrhage in patients with AF compared with those of warfarin...
  54. pmc Comparison of risk stratification schemes to predict thromboembolism in people with nonvalvular atrial fibrillation
    Margaret C Fang
    Department of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Coll Cardiol 51:810-5. 2008
    ..We assessed 5 risk stratification schemes for their ability to predict atrial fibrillation (AF)-related thromboembolism in a large community-based cohort...
  55. ncbi Health-related quality of life and estimates of utility in chronic kidney disease
    Irina Gorodetskaya
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA 94118 1211, USA
    Kidney Int 68:2801-8. 2005
    ..Health-related quality of life and estimates of utility have been carefully evaluated in persons with end-stage renal disease. Fewer studies have examined these parameters in persons with chronic kidney disease (CKD)...
  56. ncbi Risks for end-stage renal disease, cardiovascular events, and death in Hispanic versus non-Hispanic white adults with chronic kidney disease
    Carmen A Peralta
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway Street, 3rd Floor, Oakland, CA 94612 2304, USA
    J Am Soc Nephrol 17:2892-9. 2006
    ..The higher prevalence of diabetes among Hispanic patients only partially explained the increased risk for ESRD. Further studies are required to elucidate the cause(s) of ethnic disparities in CKD-associated outcomes...
  57. ncbi Patient sex and quality of ED care for patients with myocardial infarction
    David R Vinson
    Permanente Medical Group, Sacramento, CA, USA
    Am J Emerg Med 25:996-1003. 2007
    ..The aim of the study was to assess the quality of care between male and female emergency department (ED) patients with acute myocardial infarction (AMI)...
  58. ncbi GFR, body mass index, and low high-density lipoprotein concentration in adults with and without CKD
    Joan C Lo
    Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
    Am J Kidney Dis 50:552-8. 2007
    ..Low high-density lipoprotein (HDL) cholesterol level is common in patients with chronic kidney disease, but associations between severity of chronic kidney disease, obesity, and HDL level have not been well defined...
  59. doi A protocol for active surveillance of acute myocardial infarction in association with the use of a new antidiabetic pharmaceutical agent
    Bruce Fireman
    Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
    Pharmacoepidemiol Drug Saf 21:282-90. 2012
    ..To describe a protocol for active surveillance of acute myocardial infarction (AMI) in users of a recently approved oral antidiabetic medication, saxagliptin, and to provide the rationale for decisions made in drafting the protocol...
  60. ncbi Differential mortality and transplantation rates among Asians and Pacific Islanders with ESRD
    Yoshio N Hall
    Departments of Medicine, University of California San Francisco, San Francisco, CA 94118 1211, USA
    J Am Soc Nephrol 16:3711-20. 2005
    ..Strategies that are aimed at improving access to transplantation in Asian and Pacific Islander communities may further enhance survival among Asians and Pacific Islanders with ESRD...
  61. ncbi Body mass index and risk for end-stage renal disease
    Chi yuan Hsu
    Division of Nephrology, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Ann Intern Med 144:21-8. 2006
    ..Although interest in the relationship between obesity and kidney disease is increasing, few epidemiologic studies have examined whether excess weight is an independent risk factor for end-stage renal disease (ESRD)...
  62. ncbi Racial variation in the prevalence of atrial fibrillation among patients with heart failure: the Epidemiology, Practice, Outcomes, and Costs of Heart Failure (EPOCH) study
    Bernice Ruo
    General Internal Medicine Section, San Francisco Veterans Administration Medical Center, San Francisco, California, USA
    J Am Coll Cardiol 43:429-35. 2004
    ..This study was designed to determine the association between race and atrial fibrillation (AF) among patients with heart failure (HF)...
  63. ncbi Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?
    Carlos Iribarren
    Kaiser Permanente Division of Research, Oakland, California 94612, USA
    J Am Coll Cardiol 48:1800-7. 2006
    ....
  64. doi Oral health considerations in older women receiving oral bisphosphonate therapy
    Joan C Lo
    Division of Research, Kaiser Permanente Northern California, Oakland, California, USA
    J Am Geriatr Soc 59:916-22. 2011
    ..These data support efforts to optimize oral health and to identify risk factors for BRONJ in older individuals receiving bisphosphonate drugs...
  65. doi Long-term survival after ischemic stroke in patients with atrial fibrillation
    Margaret C Fang
    From the Departments of Medicine M C F, A S G and Epidemiology and Biostatistics A S G, University of California, San Francisco Division of Research A S G, N K P, N U, Kaiser Permanente of Northern California, Oakland and Clinical Epidemiology Unit Y C, L H B, D E S, General Medicine Division, Massachusetts General Hospital, Boston
    Neurology 82:1033-7. 2014
    ..While the short-term impact of atrial fibrillation-related stroke has been well studied, surprisingly little is known about its long-term effect on survival...
  66. doi Effectiveness and safety of spironolactone for systolic heart failure
    Keane K Lee
    Division of Research, Kaiser Permanente Northern California, Oakland, California Department of Cardiology, Kaiser Permanente Santa Clara Medical Center, Santa Clara, California Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California Electronic address
    Am J Cardiol 112:1427-32. 2013
    ..Our findings suggest that the benefits of spironolactone in clinical practice may be reduced compared with other guideline-recommended medications...
  67. ncbi Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease
    Joan C Lo
    Divisions of Endocrinology and Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Kidney Int 67:1047-52. 2005
    ..Previous studies have suggested a higher prevalence of thyroid abnormalities in persons with end-stage renal disease. However, little is known regarding the epidemiology of thyroid disorders in persons with less severe kidney dysfunction...
  68. pmc Chronic conditions and mortality among the oldest old
    Sei J Lee
    San Francisco Veterans Affairs Medical Center, Health Services Research and Development Research Enhancement Award Program, San Francisco, CA 94121, USA
    Am J Public Health 98:1209-14. 2008
    ..We sought to determine whether chronic conditions and functional limitations are equally predictive of mortality among older adults...
  69. ncbi Traditional and novel risk factors for clinically diagnosed abdominal aortic aneurysm: the Kaiser multiphasic health checkup cohort study
    Carlos Iribarren
    Kaiser Permanente of Northern California Division of Research, Oakland, CA 94612, USA
    Ann Epidemiol 17:669-78. 2007
    ....
  70. doi Cost-effectiveness of using high-sensitivity C-reactive protein to identify intermediate- and low-cardiovascular-risk individuals for statin therapy
    Keane K Lee
    Stanford University Schools of Medicine, CA, USA
    Circulation 122:1478-87. 2010
    ..High sensitivity C-reactive protein (hs-CRP) testing has been advocated to identify low- and intermediate-risk individuals who may benefit from statin therapy...
  71. doi Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification
    Masahiro Terashima
    Stanford University School of Medicine, California, USA
    JACC Cardiovasc Imaging 1:167-73. 2008
    ..This study evaluated the hypothesis that impaired nitroglycerin (NTG)-induced coronary vasodilation is associated with advanced coronary atherosclerosis in asymptomatic older patients...
  72. pmc Associations between kidney function and subclinical cardiac abnormalities in CKD
    Meyeon Park
    Division of Nephrology, University of California, 521 Parnassus Avenue, San Francisco, CA 94143, USA
    J Am Soc Nephrol 23:1725-34. 2012
    ..We did not detect significant associations between kidney function and systolic or diastolic function after adjusting for potential confounding variables...
  73. doi Procedural complications, rehospitalizations, and repeat procedures after catheter ablation for atrial fibrillation
    Rashmee U Shah
    Stanford University School of Medicine, California, USA
    J Am Coll Cardiol 59:143-9. 2012
    ..The purpose of this study was to estimate rates and identify predictors of inpatient complications and 30-day readmissions, as well as repeat hospitalization rates for arrhythmia recurrence following atrial fibrillation (AF) ablation...
  74. ncbi Efficacy of anticoagulation for stroke prevention and risk stratification in atrial fibrillation: translating trials into clinical practice
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, USA
    Am J Manag Care 10:S58-65. 2004
    ..Such strategies would enhance the net benefit of oral anticoagulation. Concluding points provide information on improving risk stratification for stroke in patients with AF...
  75. doi Prevalence of osteonecrosis of the jaw in patients with oral bisphosphonate exposure
    Joan C Lo
    Research Scientist, Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA
    J Oral Maxillofac Surg 68:243-53. 2010
    ..The present study examined the prevalence of ONJ in patients receiving chronic oral bisphosphonate therapy...
  76. pmc Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study
    Kristine Yaffe
    Department of Psychiatry, School of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 58:338-45. 2010
    ....
  77. ncbi The importance of anticoagulation management services
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, Calif, USA
    Manag Care 13:20-5. 2004
  78. pmc ADHD medications and risk of serious cardiovascular events in young and middle-aged adults
    Laurel A Habel
    Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Fifth Floor, Oakland, CA 94612, USA
    JAMA 306:2673-83. 2011
    ..These agents can increase heart rate and blood pressure, raising concerns about their cardiovascular safety...
  79. pmc Cardiology clinical trial participation in community-based healthcare systems: obstacles and opportunities
    Carol P Somkin
    Division of Research, Kaiser Permanente Northern California, Oakland, California, USA
    Contemp Clin Trials 29:646-53. 2008
    ..Community-based health systems could be an important source of participants and investigators, but little is known about community cardiologists' experiences with trials...
  80. doi Epidemiology of peripartum cardiomyopathy: incidence, predictors, and outcomes
    Erica P Gunderson
    Division of Research, Kaiser Permanente of Northern California, Oakland, California 94612 2304, USA
    Obstet Gynecol 118:583-91. 2011
    ....
  81. ncbi Older emergency department patients with acute myocardial infarction receive lower quality of care than younger patients
    David J Magid
    Kaiser Permanente Clinical Research Unit, Denver, CO 90237 8066, USA
    Ann Emerg Med 46:14-21. 2005
    ..We assessed the independent relationship between age and the quality of medical care provided to patients presenting to the emergency department (ED) with acute myocardial infarction...
  82. ncbi Effect of race/ethnicity on the efficacy of warfarin: potential implications for prevention of stroke in patients with atrial fibrillation
    Albert Yuh Jer Shen
    Department of Cardiology, Kaiser Permanente Medical Center, Los Angeles, California 90027, USA
    CNS Drugs 22:815-25. 2008
    ..Whether the same net clinical benefit extends to persons of colour is unproven. Given the rapidly changing demographic nationally and internationally, additional research is needed to resolve this important question...
  83. pmc Statin use and risk of basal cell carcinoma
    Maryam M Asgari
    Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612, USA
    J Am Acad Dermatol 61:66-72. 2009
    ..We examined the association between statin use and basal cell carcinoma (BCC) risk...
  84. pmc Glycemic response to newly initiated diabetes therapies
    Andrew J Karter
    Division of Research, Kaiser Permanente, 2000 Broadway, Oakland, CA 94612, USA
    Am J Manag Care 13:598-606. 2007
    ..The glycemic response to antihyperglycemic therapies for type 2 diabetes has been thoroughly evaluated in randomized controlled trials, but inadequately studied in real-world settings...
  85. ncbi Response to newly prescribed lipid-lowering therapy in patients with and without HIV infection
    Michael J Silverberg
    Kaiser Permanente Northern California, Oakland, California, USA
    Ann Intern Med 150:301-13. 2009
    ..Antiretroviral agents, particularly protease inhibitors (PIs), may adversely affect lipid levels in patients with HIV infection. However, it is not known whether HIV-associated dyslipidemia is more difficult to treat...
  86. ncbi Electrocardiographic findings predict short-term cardiac morbidity after transient ischemic attack
    Jacob S Elkins
    Department of Neurology, UCSF Box 0114, University of California, San Francisco, 505 Parnassus Ave, Room M 798, San Francisco, CA 94143 0114, USA
    Arch Neurol 59:1437-41. 2002
    ..Current guidelines recommend the use of electrocardiography (ECG) in the evaluation of transient ischemic attack (TIA), but the data supporting its value in acute management are sparse...
  87. ncbi The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods
    Harold I Feldman
    Center for Clinical Epidemiology, Philadelphia, 19104, USA
    J Am Soc Nephrol 14:S148-53. 2003
    ..Insights from CRIC should lead to the formulation of hypotheses regarding therapy that will serve as the basis for targeted interventional trials focused on reducing the burden of CRI and CVD...
  88. ncbi Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation
    Elaine M Hylek
    General Medicine Division, Clinical Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    N Engl J Med 349:1019-26. 2003
    ..0 or greater. The effect of the intensity of oral anticoagulation on the severity of atrial fibrillation-related stroke is not known but is central to the choice of the target INR...
  89. ncbi ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Com
    Robert L McNamara
    Circulation 109:3223-43. 2004
  90. ncbi ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with atrial fibrillation: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Com
    Robert L McNamara
    J Am Coll Cardiol 44:475-95. 2004
  91. ncbi Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Daniel E Singer
    Clinical Epidemiology Unit, S50 9, Massachusetts General Hospital, Boston, MA 02114, USA
    Chest 126:429S-456S. 2004
    ..However, in patients without contraindications to anticoagulation, we suggest beginning IV heparin or low molecular weight heparin at presentation (Grade 2C)...
  92. ncbi Effects of erythropoietin on left ventricular hypertrophy in adults with severe chronic renal failure and hemoglobin <10 g/dL
    Juan Carlos Ayus
    The University of Texas Health Science Center at San Antonio, San Antonio, Texas 782293, USA
    Kidney Int 68:788-95. 2005
    ..Left ventricular hypertrophy (LVH) frequently complicates chronic renal insufficiency. Anemia is also common in these patients and may contribute to LVH...
  93. ncbi Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction
    Joshua W Knowles
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1052-8. 2007
    ..Genetic polymorphisms may affect the balance between coagulation and fibrinolysis and thereby affect individual vulnerability to acute myocardial infarction (MI) among patients with underlying coronary atherosclerosis...
  94. ncbi Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease
    Mark A Hlatky
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1043-51. 2007
    ..The aim of this study was to assess systematic differences between patients with acute myocardial infarction (MI) and patients with stable angina in matrix metalloproteinase (MMP) circulating levels and genetic polymorphisms...
  95. ncbi Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
    Mark A Hlatky
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1035-42. 2007
    ..The goal of this study was to assess whether polymorphisms in genes encoding elements of pathways mediating the response to ischemia affect vulnerability to MI among patients with underlying CAD...
  96. pmc Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study
    Themistocles L Assimes
    Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 5406, USA
    Hum Mol Genet 17:2320-8. 2008
    ..Further investigations in other populations are needed to confirm or refute our findings...
  97. doi Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    Daniel E Singer
    Clinical Epidemiology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Chest 133:546S-592S. 2008
    ..However, in patients without contraindications to anticoagulation, we suggest beginning IV heparin or LMWH at presentation (Grade 2C)...
  98. doi Epidemiology of acute infections among patients with chronic kidney disease
    Lorien S Dalrymple
    Department of Internal Medicine, Division of Nephrology, University of California at Davis, Sacramento, CA 95817, USA
    Clin J Am Soc Nephrol 3:1487-93. 2008
    ..Future research is needed to delineate accurately the epidemiology of infections in these populations and to develop effective preventive strategies across the spectrum of CKD severity...
  99. ncbi Do plasma biomarkers of coagulation and fibrinolysis differ between patients who have experienced an acute myocardial infarction versus stable exertional angina?
    Haruka Itakura
    Stanford University School of Medicine, Stanford, CA 94305 5405, USA
    Am Heart J 154:1059-64. 2007
    ..Circulating concentrations of proteins associated with coagulation and fibrinolysis may differ between individuals with coronary artery disease (CAD) who develop an acute myocardial infarction (AMI) rather than stable exertional angina...
  100. ncbi Chronic kidney disease, anemia, and epoetin
    Alan S Go
    N Engl J Med 356:957; author reply 958-9. 2007

Research Grants7

  1. Study of the Care and Outcomes of Renal Insufficiency
    Alan Go; Fiscal Year: 2007
    ..abstract_text> ..
  2. HMO Research Network Cardiovascular Research Network
    Alan Go; Fiscal Year: 2007
    ..Section A: Overall Program Review ..
  3. Study of the Care and Outcomes of Renal Insufficiency
    Alan Go; Fiscal Year: 2007
    ..area compared to serum creatinine, estimated or measured creatinine clearance, estimated glomerular filtration rate and measured absolute glomerular filtration rate across different demographic and disease subgroups ..