Research Topics
| Lisa CroenSummaryAffiliation: Kaiser Permanente Country: USA Publications
Research Grants
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Detail Information
Publications
Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control studyPaula E Goines
Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 Health Sciences Dr, Suite 6510, Davis, CA 95616, USA
Mol Autism 2:13. 2011..abstract:..
The changing prevalence of autism in CaliforniaLisa A Croen
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland 94606 5226, USA
J Autism Dev Disord 32:207-15. 2002..3 per 10,000. These data suggest that improvements in detection and changes in diagnosis account for the observed increase in autism; whether there has also been a true increase in incidence is not known...
Antidepressant use during pregnancy and childhood autism spectrum disordersLisa A Croen
Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
Arch Gen Psychiatry 68:1104-12. 2011..Use of antidepressant medications during pregnancy also shows a secular increase in recent decades, prompting concerns that prenatal exposure may contribute to increased risk of ASD...- Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) StudyLisa A Croen
Division of Research, Kaiser Permanente Northern California, Oakland, California 94612, USA
Autism Res 1:130-7. 2008.... - Maternal mid-pregnancy autoantibodies to fetal brain protein: the early markers for autism studyLisa A Croen
Division of Research, Kaiser Permanente Northern California, Oakland, California 94612, USA
Biol Psychiatry 64:583-8. 2008..Immune dysfunction has been associated with autism, yet whether maternal immune status during pregnancy plays a causal role remains to be clarified... - Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disordersLisa A Croen
Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
Am J Obstet Gynecol 199:234.e1-6. 2008..The objective of the study was to investigate the association between maternal Rh D status, prenatal exposure to anti-D immune globulin, and the risk of autism in the offspring... - Maternal and paternal age and risk of autism spectrum disordersLisa A Croen
Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA 94612, USA
Arch Pediatr Adolesc Med 161:334-40. 2007..To explore the association between maternal and paternal age and risk of autism spectrum disorders (ASDs) in offspring... - A comparison of health care utilization and costs of children with and without autism spectrum disorders in a large group-model health planLisa A Croen
Division of Research, Kaiser Foundation Research Institute, Kaiser Permanente, 2000 Broadway, Oakland, CA 94612, USA
Pediatrics 118:e1203-11. 2006..Our purpose for this study was to compare health care utilization and costs of children with and without autism spectrum disorders in the same health plan... - Maternal autoimmune diseases, asthma and allergies, and childhood autism spectrum disorders: a case-control studyLisa A Croen
Division of Research, Kaiser Foundation Research Institute, Kaiser Permanente, Oakland, Calif 94612, USA
Arch Pediatr Adolesc Med 159:151-7. 2005..To investigate the association between physician-documented diagnoses of maternal autoimmune diseases, allergies, and asthma around the time of pregnancy and subsequent diagnoses of autism in children... - Prenatal exposure to β2-adrenergic receptor agonists and risk of autism spectrum disordersLisa A Croen
Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA, 94612, USA
J Neurodev Disord 3:307-15. 2011..Should this result be confirmed in larger samples, it would point to late pregnancy as an etiologic window of interest in autism risk factor research... - Descriptive epidemiology of autism in a California population: who is at risk?Lisa A Croen
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland 94606 5226, USA
J Autism Dev Disord 32:217-24. 2002..Environmental factors associated with these demographic characteristics may interact with genetic vulnerability to increase the risk of autism... - Neonatal hyperbilirubinemia and risk of autism spectrum disordersLisa A Croen
Kaiser Permanente, Division of Research, 2000 Broadway, Oakland, CA 94612, USA
Pediatrics 115:e135-8. 2005..To investigate the association between neonatal hyperbilirubinemia and autism spectrum disorders (ASD)... - Mothers of children diagnosed with attention-deficit/hyperactivity disorder: health conditions and medical care utilization in periods before and after birth of the childG Thomas Ray
Division of Research, Kaiser Permanente Medical Care Program, Northern California Region, Oakland, CA 94612, USA
Med Care 47:105-14. 2009..Analyzing health conditions and medical utilization of mothers of children with attention-deficit/hyperactivity disorder (ADHD) can shed light on biologic, environmental, and psychosocial factors relating to ADHD... - Attention-deficit/hyperactivity disorder in children: excess costs before and after initial diagnosis and treatment cost differences by ethnicityG Thomas Ray
Division of Research, Kaiser Permanente Medical Care Program, Northern California Region, Oakland, Calif 94612, USA
Arch Pediatr Adolesc Med 160:1063-9. 2006..To estimate the excess costs for children in the years surrounding initial diagnosis of attention-deficit/hyperactivity disorder (ADHD) and to estimate differences in treatment costs by ethnicity... - Socio-economic status and risk of conotruncal heart defects and orofacial cleftsSuzan L Carmichael
March of Dimes Birth Defects Foundation California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA 94710, USA
Paediatr Perinat Epidemiol 17:264-71. 2003..4 for dTGA, and ORs for all six measures were < 0.7 for TOF. ORs for clefts tended to be closer to 1. This study suggests that SES risks are birth defect specific... - Infection in the first 2 years of life and autism spectrum disordersNila J Rosen
Division of Research, Kaiser Permanente, Oakland, California, USA
Pediatrics 119:e61-9. 2007..The purpose of this work was to investigate the association between infections in the first 2 years and subsequent diagnosis of autism spectrum disorders... - Identifying environmental contributions to autism: provocative clues and false leadsCindy P Lawler
Division of Extramural Research and Training, National Institute of Environmental Health Sciences, PO Box 1123, MD EC 23, Research Triangle Park, NC 27709, USA
Ment Retard Dev Disabil Res Rev 10:292-302. 2004..Anticipated discoveries in genetics, brain pathology, and the molecular/cellular basis of functional impairment in ASD are likely to provide new opportunities to explore environmental aspects of this disorder... - Perinatal stroke in children with motor impairment: a population-based studyYvonne W Wu
Department of Neurology, University of California, San Francisco 94143 0136, USA
Pediatrics 114:612-9. 2004..Most previous studies lack an appropriate control group and include only infants with symptoms in the newborn period. We set out to determine prenatal and perinatal risk factors for PAS... - Rehospitalization in the first year of life among infants with bronchopulmonary dysplasiaVincent C Smith
Department of Neonatalogy, Beth Israel Deaconess Medical Center, and Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Pediatr 144:799-803. 2004..To describe rates and identify risk factors for rehospitalization during the first year of life among infants with bronchopulmonary dysplasia (BPD)... - Maternal and infant characteristics associated with perinatal arterial stroke in the infantJanet Lee
Department of Neurology, University of California, San Francisco, CA 94117, USA
JAMA 293:723-9. 2005..How these complications, along with their potential effects on the placenta and fetus, may play a role in causing perinatal stroke deserves further study... - Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based studyPaula Krakowiak
Division of Epidemiology, Department of Public Health Sciences, School of Medicine, University of California, Davis, CA, USA
J Sleep Res 17:197-206. 2008..Factor scores for children with DD were intermediate between the ASD and TD groups. Cognitive or adaptive development did not predict severity of sleep problems in the ASD group... - Cerebral palsy in a term population: risk factors and neuroimaging findingsYvonne W Wu
Department of Neurology, University of California, 350 Parnassus Ave, Suite 609, San Francisco, California 94143 0137, USA
Pediatrics 118:690-7. 2006..The purpose of this work was to study risk factors and neuroimaging characteristics of cerebral palsy in term and near-term infants... - Congenital anomalies associated with autism spectrum disordersMegan L Wier
California Department of Health Services, Genetic Disease Branch, Sequoia Foundation, Richmond, USA
Dev Med Child Neurol 48:500-7. 2006..1-2.4). Almost all organ-system anomaly categories were more prevalent in children with ASD, however only gastrointestinal anomalies were significantly associated with ASD in adjusted analyses (1.9 vs 0.4%, ORa 5.1, 95% CI 1.8-14.1)... - Trends in severe bronchopulmonary dysplasia rates between 1994 and 2002Vincent C Smith
Department of Neonatology, Rose 318, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
J Pediatr 146:469-73. 2005..To examine temporal trends in the rates of severe bronchopulmonary dysplasia (BPD) between 1994 and 2002... - Predictors of outcome in perinatal arterial stroke: a population-based studyJanet Lee
Department of Neurology, University of California, San Francisco, USA
Ann Neurol 58:303-8. 2005..4), Wernicke's area (RR, 2.0; 95% CI, 1.1-3.8), or basal ganglia (RR, 1.9; 95% CI, 1.1-3.3). Among infants with PAS, specific radiological findings and a lack of symptoms in the newborn period are associated with increased risk for CP... - Chorioamnionitis and cerebral palsy in term and near-term infantsYvonne W Wu
Department of Neurology, University of California, San Francisco 94143, USA
JAMA 290:2677-84. 2003..Half of all cases of cerebral palsy (CP) occur in term infants, for whom risk factors have not been clearly defined. Recent studies suggest a possible role of chorioamnionitis... 
The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autismIrva Hertz-Picciotto
Division of Epidemiology, Department of Public Health Sciences, School of Medicine, and Medical Investigations of Neurodevelopmental Disorders MIND Institute, University of California Davis, Davis, California, USA
Environ Health Perspect 114:1119-25. 2006....- Potential association between infertility and spinal neural tube defects in offspringYvonne W Wu
Department of Neurology, University of California, San Francisco, California 94143 0137, USA
Birth Defects Res A Clin Mol Teratol 76:718-22. 2006..We examined the possible association between infertility and spinal neural tube defects (NTDs)... - Neuroimaging abnormalities in infants with congenital hemiparesisYvonne W Wu
Department of Neurology, University of California, San Francisco, California 94143 0137, USA
Pediatr Neurol 35:191-6. 2006..001). Neuroimaging studies provide useful diagnostic and prognostic information in infants with congenital hemiparesis... - Regression in autism: prevalence and associated factors in the CHARGE StudyRobin L Hansen
Medical Investigation of Neurodevelopmental Disorders Institute, University of California, Davis, Sacramento 95817, USA
Ambul Pediatr 8:25-31. 2008..The aim of this study was to examine the prevalence of regressive autism and associated demographic, medical, and developmental factors by using 2 different definitions of regression based on the Autism Diagnostic Interview, Revised... - Autism: maternally derived antibodies specific for fetal brain proteinsDaniel Braunschweig
Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, CA, USA
Neurotoxicology 29:226-31. 2008.... - Gene expression changes in children with autismJeffrey P Gregg
Department of Pathology, University of California at Davis Medical Center, Sacramento, CA 95817, USA University of California at Davis, Davis, CA 95616, USA
Genomics 91:22-9. 2008..05). We conclude that the gene expression data support emerging evidence for abnormalities in peripheral blood leukocytes in autism that could represent a genetic and/or environmental predisposition to the disorder... - Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay areaGayle C Windham
Division of Environmental and Occupational Disease Control, California Department of Health Services, Richmond, California, USA
Environ Health Perspect 114:1438-44. 2006..S. Environmental Protection Agency... - The epidemiology of autism spectrum disordersCraig J Newschaffer
Department of Epidemiology and Biostatistics, Drexel University School of Public Health, Philadelphia, PA 19102, USA
Annu Rev Public Health 28:235-58. 2007....
Research Grants
- Prenatal and Neonatal Biologic Markers for AutismLisa Croen; Fiscal Year: 2006..abstract_text> ..
- Prenatal and Neonatal Biologic Markers for AutismLisa A Croen; Fiscal Year: 2010..We anticipate that the results of this study will contribute to identifying factors that increase the risk for autism and may lead to eventual prevention of autism and related disorders. ..
- Prenatal Exposure to Polyfluoroalkyl Compounds in the EMA StudyLisa A Croen; Fiscal Year: 2010..In the long-term, a better understanding of the underlying biology may suggest appropriate strategies for early intervention and contribute to the eventual prevention of this often devastating and usually life-long disability. ..