Gregory Clarke

..The authors describe the protocol they developed...

..Antidepressant (AD) dispensing for depression in youth declined in the years following the 2003-04 Food and Drug Administration actions regarding increased risk of suicidal behavior...

..We created an Internet-based, cognitive therapy, self-help program to be used as a stand-alone intervention for mild-to-moderate depression, or as an adjunct to traditional services for more severe depression...

..Highly disseminable, low-cost, and self-help interventions such as this have the potential to deliver a significant public health benefit...

..We hypothesized that methods to increase participant usage of the intervention, such as postcard or telephone reminders, might result in significant effects on depression...

..To test a collaborative-care, cognitive-behavioral therapy (CBT) program adjunctive to selective serotonin reuptake inhibitor (SSRI) treatment in HMO pediatric primary care...

..To the extent that providers improve efforts to help teens feel normal, autonomous, and connected, the teens report they are more likely to accept treatment for depression and report success in treatment...

..However, given that many other studies have found positive effects of CBT for youth depression, this single study should not be viewed as evidence that CBT is ineffective overall...

..Results suggest that psychopathology plays a more prominent role in maintaining adolescent depression than demographic or psychosocial factors...

..This paper reviews data currently available on the cost of depression in childhood and the cost effectiveness of interventions to treat and prevent depression in this population...

..Findings suggest that reducing negative thinking may be the primary mechanism through which the CWD-A intervention reduces depression...

..To evaluate effectiveness of the Adolescent Coping With Depression (CWD-A) course, a cognitive-behavioral group intervention for depressed adolescents with comorbid conduct disorder...

..Depression is common in adolescent offspring of depressed parents and can be prevented, but adoption of prevention programs is dependent on the balance of their incremental costs and benefits...

..This site is based in Pittsburgh, which also serves as the Data Coordinating Center for the study ..

..This application is based in Nashville (Judy Garber, PI), and interlocks with applications from Boston (William Beardslee, PI), Pittsburgh (David Brent, PI), and Portland (Greg Clarke, PI). ..

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..This study also will identify youth who are most likely to benefit from this program, and will inform us about how to create future prevention programs that help those youth who did not benefit. ..

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..This study also will identify youth who are most likely to benefit from this program, and will inform us about how to create future prevention programs that help those youth who did not benefit. ..

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..This program is low cost and can be delivered to widespread populations much more easily than other approaches. ..

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..We predict that while initial HMO health care utilization and costs will be higher for the CC-CBT intervention will be more cost effective (e.g., units of improvement per unit of cost) compared to usual care. ..

..This is a particularly important question, given the high risk of depression relapse/recurrence in these youth. ..

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