Genomes and Genes


Bette J Caan


Affiliation: Kaiser Permanente
Country: USA


  1. Cespedes Feliciano E, Kroenke C, Caan B. The Plausibility of the Obesity Paradox in Cancer-Response-Reply to Point. Cancer Res. 2018;78:1904-1905 pubmed publisher
  2. Caan B, Cespedes Feliciano E, Kroenke C. The Importance of Body Composition in Explaining the Overweight Paradox in Cancer-Counterpoint. Cancer Res. 2018;78:1906-1912 pubmed publisher
    ..More research utilizing body composition is needed to clarify the effects of adiposity on cancer mortality. Cancer Res; 78(8); 1906-12. ©2018 AACR. ..
  3. Kwan M, Kroenke C, Sweeney C, Bernard P, Weltzien E, Castillo A, et al. Association of high obesity with PAM50 breast cancer intrinsic subtypes and gene expression. BMC Cancer. 2015;15:278 pubmed publisher
    ..ER expression may not increase correspondingly with increasing degree of obesity. Highly obese patients are more likely to have tumor subtypes associated with high proliferation and poorer prognosis. ..
  4. Caan B, Meyerhardt J, Kroenke C, Alexeeff S, Xiao J, Weltzien E, et al. Explaining the Obesity Paradox: The Association between Body Composition and Colorectal Cancer Survival (C-SCANS Study). Cancer Epidemiol Biomarkers Prev. 2017;26:1008-1015 pubmed publisher
    ..i>Cancer Epidemiol Biomarkers Prev; 26(7); 1008-15. ©2017 AACR. ..
  5. Sharafeldin N, Slattery M, Liu Q, Franco Villalobos C, Caan B, Potter J, et al. Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..GEIs between angiogenesis genes and smoking, alcohol, and animal protein impact rectal cancer risk. Our results support the importance of considering the biologic hypothesis to characterize GEIs associated with cancer outcomes. ..