Research Topics
| Laurent RivorySummaryAffiliation: Johnson and Johnson Pharmaceutical Research and Development Country: USA Publications
| Collaborators |
Detail Information
Publications
The DNAzymes Rs6, Dz13, and DzF have potent biologic effects independent of catalytic activityLaurent Rivory
Johnson and Johnson Research Pty, Ltd, Eveleigh, NSW, 1430, Australia
Oligonucleotides 16:297-312. 2006..These data reveal that the biologic activity of several published DNAzymes is not mediated through the catalytic degradation of target mRNA...
Sequence determinants of innate immune activation by short interfering RNAsAmber Goodchild
Johnson and Johnson Research Pty Ltd, Strawberry Hills, NSW, Australia
BMC Immunol 10:40. 2009....
Dz13, a DNAzyme targeting c-jun, induces off-target cytotoxicity in endothelial cells with features of nonapoptotic programmed cell deathMary Margaret Gozar
Johnson and Johnson Research Pty Limited, Eveleigh, New South Wales, 1430, Australia
Oligonucleotides 18:257-68. 2008....
Cytotoxic G-rich oligodeoxynucleotides: putative protein targets and required sequence motifAmber Goodchild
Johnson and Johnson Research Pty Ltd, Eveleigh, NSW, 1430, Australia
Nucleic Acids Res 35:4562-72. 2007....
