Affiliation: Johnson and Johnson Pharmaceutical Research and Development
- The DNAzymes Rs6, Dz13, and DzF have potent biologic effects independent of catalytic activityLaurent Rivory
Johnson and Johnson Research Pty, Ltd, Eveleigh, NSW, 1430, Australia
Oligonucleotides 16:297-312. 2006..These data reveal that the biologic activity of several published DNAzymes is not mediated through the catalytic degradation of target mRNA...
- Sequence determinants of innate immune activation by short interfering RNAsAmber Goodchild
Johnson and Johnson Research Pty Ltd, Strawberry Hills, NSW, Australia
BMC Immunol 10:40. 2009....
- Dz13, a DNAzyme targeting c-jun, induces off-target cytotoxicity in endothelial cells with features of nonapoptotic programmed cell deathMary Margaret Gozar
Johnson and Johnson Research Pty Limited, Eveleigh, New South Wales, 1430, Australia
Oligonucleotides 18:257-68. 2008....
- Cytotoxic G-rich oligodeoxynucleotides: putative protein targets and required sequence motifAmber Goodchild
Johnson and Johnson Research Pty Ltd, Eveleigh, NSW, 1430, Australia
Nucleic Acids Res 35:4562-72. 2007....