Research Topics
| Rossella MedoriSummaryAffiliation: Johnson and Johnson Pharmaceutical Research and Development Country: USA Publications
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Detail Information
Publications
A randomized, placebo-controlled trial of three fixed dosages of prolonged-release OROS methylphenidate in adults with attention-deficit/hyperactivity disorderRossella Medori
Janssen Cilag EMEA, Neuss, Germany
Biol Psychiatry 63:981-9. 2008..There is increasing recognition of attention-deficit/hyperactivity disorder (ADHD) in adults and the need to evaluate efficacy and safety of methylphenidate treatment in these patients...
Plasma antipsychotic concentration and receptor occupancy, with special focus on risperidone long-acting injectableRossella Medori
Janssen Cilag, Medical Affairs EMEA, Beerse, Belgium
Eur Neuropsychopharmacol 16:233-40. 2006..m. every 2 weeks. The constant and slow release of the long-acting formulation leads to less fluctuation in plasma levels and to a D(2)-like receptor occupancy which is below the threshold for EPS...
Long-acting injectable risperidone in the treatment of subjects with recent-onset psychosis: a preliminary studyRobin Emsley
University of Stellenbosch, Tygerberg, Cape Town, South Africa
J Clin Psychopharmacol 28:210-3. 2008..5 mg for 30%, and 50 mg for 16%. This preliminary study suggests that RLAI was overall well tolerated and appears to be effective in recent-onset psychosis. Further investigation is warranted...
Concordance of patient and clinical ratings of symptom severity and change of psychotic illnessJonathan Rabinowitz
Schizophr Res 100:359-60. 2008
Long-term safety and efficacy of long-acting risperidone in elderly psychotic patientsWerner Kissling
Klinikum rechts der Isar, Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Munchen, Germany
Hum Psychopharmacol 22:505-13. 2007..This post-hoc analysis supports that RLAI is well tolerated and safe in elderly patients with psychotic illnesses switched from stable antipsychotic regimens, and suggests possible efficacy, although inferences are limited...
Efficacy and safety of risperidone long-acting injectable in stable psychotic patients previously treated with oral risperidoneMax Schmauss
Department of Psychiatry, Bezirkskrankenhaus Augsburg, Augsburg, Germany
Int Clin Psychopharmacol 22:85-92. 2007..001). These results indicate that further improvement in symptom control can be seen after a change to risperidone long-acting injectable in clinically stable patients previously treated with oral risperidone...
Remission in early psychosis: Rates, predictors, and clinical and functional outcome correlatesRobin Emsley
University of Stellenbosch, Tygerberg, Cape Town, South Africa
Schizophr Res 89:129-39. 2007..Recently, the "Remission in Schizophrenia Working Group" proposed remission criteria consisting of a reduction to mild levels on key symptoms for at least 6 months...
[Switching from a short-acting to a long-acting methylphenidate preparation: a multicentre, open study in children with ADHD]Steffen Heger
,
Z Kinder Jugendpsychiatr Psychother 34:257-65. 2006..In a school setting, the efficacy of OROS-MPH was comparable to that of IR-MPH...
Time course for antipsychotic treatment response in first-episode schizophreniaRobin Emsley
Department of Social Work, Bar Ilan University, Ramat Gan, Israel
Am J Psychiatry 163:743-5. 2006..0%, 44.8%, and 27.5% of patients. CONCLUSIONS: Time to antipsychotic response varied widely, suggesting that, in first-episode schizophrenia, longer treatment trials may be necessary...
Efficacy and safety of direct transition to risperidone long-acting injectable in patients treated with various antipsychotic therapiesHans Jurgen Moller
Department of Psychiatry, University of Munich, Germany
Int Clin Psychopharmacol 20:121-30. 2005..Direct initiation of RLAI was effective and well tolerated. RLAI provides an advancement in the treatment options available for a wide range of patients requiring long-term antipsychotic therapy...
Oral risperidone plus oral lorazepam versus standard care with intramuscular conventional neuroleptics in the initial phase of treating individuals with acute psychosisJoseph Lejeune
CHR Citadelle, , Belgium
Int Clin Psychopharmacol 19:259-69. 2004..m. conventional neuroleptic treatment with or without lorazepam. Oral risperidone plus lorazepam rapidly reduces symptoms, including aggression, and causes fewer EPS...
Orally versus intramuscularly administered antipsychotic drugs in psychiatric emergenciesGlenn W Currier
University of Rochester Medical Center, Rochester, New York, 14642, USA
J Psychiatr Pract 12:30-40. 2006..A synthesis of data from individual clinical trials, meta-analyses, review articles, and expert consensus recommendations is used to develop a working clinical algorithm for the acute management of aggression and agitation...
[Tardive dyskinesia: pergolid, a possible therapeutic option]Alexander Diehl
Zentralinstitut fur Seelische Gesundheit, Mannheim, Germany
Psychiatr Prax 30:333-7. 2003..Low-dose pergolide should activate presynaptic auto receptors, decrease dopamintransmission and reduce tardive dyskinesia...
