- Bipolar disorder: from genes to behavior pathwaysKeri Martinowich
Johnson and Johnson Pharmaceutical Research and Development, 1125 Trenton Harbourton Road, E32000, Titusville, New Jersey 08560, USA
J Clin Invest 119:726-36. 2009..We conclude with a synthesis of where the field stands and with suggestions and strategies for future areas of study to further increase our conceptual understanding of this complex illness...
- Acetylcholinesterase inhibition ameliorates deficits in motivational driveKeri Martinowich
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3711, USA
Behav Brain Funct 8:15. 2012..This study evaluated a chronic restraint stress (CRS) protocol in modeling apathetic behavior, and determined whether administration of an anticholinesterase had utility in attenuating CRS-induced phenotypes...
- Impaired mitochondrial function in psychiatric disordersHusseini Manji
Janssen Research and Development, LLC, Raritan, New Jersey 08869, USA
Nat Rev Neurosci 13:293-307. 2012..Enhancing mitochondrial function could represent an important avenue for the development of novel therapeutics and also presents an opportunity for a potentially more efficient drug-development process...