Affiliation: Johnson and Johnson Pharmaceutical Research and Development
- Determining the cutoff based on a continuous variable to define two populations with application to vaccinesShu Li
Clinical Biostatistics, Johnson and Johnson Pharmaceutical Research and Development, Wayne, PA, USA
J Biopharm Stat 23:662-80. 2013..g., normal, log-normal and exponential distribution) of the continuous variable. Finally, we applied the proposed methods to a varicella vaccine example...
- Use of statistical models for evaluating antibody response as a correlate of protection against varicellaIvan S F Chan
Clinical Biostatistics, Merck Research Laboratories, Merck and Co, West Point, PA 19486, USA
Stat Med 21:3411-30. 2002..In addition, we explore the potential use of these models to predict long-term disease breakthrough rates and to estimate the predicted vaccine efficacy of a similar varicella vaccine made with a modified manufacturing process...