J Aerssens

Summary

Affiliation: Johnson and Johnson Pharmaceutical Research and Development
Country: USA

Publications

  1. ncbi request reprint APOE genotype: no influence on galantamine treatment efficacy nor on rate of decline in Alzheimer's disease
    J Aerssens
    Department of Pharmacogenomics, Janssen Research Foundation, Beerse, Belgium
    Dement Geriatr Cogn Disord 12:69-77. 2001
  2. ncbi request reprint Regional assignment of seven loci to 12p13.2-pter by PCR analysis of somatic cell hybrids containing the der(12) or the der(X) chromosome from a mesothelioma showing t(X;12)(q22;p13)
    J Aerssens
    Arthritis and Metabolic Bone Disease Research Unit, Center for Human Genetics K U, Leuven, Belgium
    Genomics 20:119-21. 1994
  3. ncbi request reprint Assignment of the gene for the human proliferating cell nucleolar protein P120 (NOL1) to chromosome 12p13 by fluorescence in situ hybridization and polymerase chain reaction with somatic cell hybrids
    M Baens
    Human Genome Laboratory, University of Leuven, Belgium
    Genomics 21:296-7. 1994
  4. ncbi request reprint Isolation and regional assignment of human chromosome 12p cDNAs
    M Baens
    Human Genome Analysis Laboratory, University of Leuven, Belgium
    Genomics 29:44-52. 1995
  5. ncbi request reprint Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case
    I Wlodarska
    Center for Human Genetics, Flanders Interuniversity Institute for Biotechnology, Leuven, Belgium
    Cancer Res 56:2655-61. 1996
  6. ncbi request reprint Quantitative trait loci for human muscle strength: linkage analysis of myostatin pathway genes
    W Huygens
    Research Center for Exercise and Health, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Belgium
    Physiol Genomics 22:390-7. 2005
  7. ncbi request reprint Validation of 16S rDNA sequencing in microdissected bowel biopsies from Crohn's disease patients to assess bacterial flora diversity
    G De Hertogh
    Department of Morphology and Molecular Pathology, University Hospitals KULeuven, Belgium
    J Pathol 209:532-9. 2006
  8. ncbi request reprint Polymorphisms in the vitamin D receptor gene are associated with muscle strength in men and women
    A Windelinckx
    Research Center for Exercise and Health, Department of Biomedical Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, B 3001, Leuven, Belgium
    Osteoporos Int 18:1235-42. 2007

Collaborators

  • S Lilienfeld
  • G Matthijs
  • P R Rutgeerts
  • Severine Vermeire
  • A Windelinckx
  • M A I Thomis
  • G De Hertogh
  • W Huygens
  • M Baens
  • P Peeters
  • J Lefevre
  • C Delecluse
  • G De Mars
  • G Beunen
  • P Van Eyken
  • N Ectors
  • B Coulie
  • K Geboes
  • P Verhasselt
  • R de Hoogt
  • R Vlietinck
  • M W Peeters
  • P Marynen
  • G P Beunen
  • I Wlodarska
  • H Van den Berghe
  • P Brock
  • C Mecucci
  • K Van Zand
  • M Chaffanet
  • J J Cassiman

Detail Information

Publications8

  1. ncbi request reprint APOE genotype: no influence on galantamine treatment efficacy nor on rate of decline in Alzheimer's disease
    J Aerssens
    Department of Pharmacogenomics, Janssen Research Foundation, Beerse, Belgium
    Dement Geriatr Cogn Disord 12:69-77. 2001
    ....
  2. ncbi request reprint Regional assignment of seven loci to 12p13.2-pter by PCR analysis of somatic cell hybrids containing the der(12) or the der(X) chromosome from a mesothelioma showing t(X;12)(q22;p13)
    J Aerssens
    Arthritis and Metabolic Bone Disease Research Unit, Center for Human Genetics K U, Leuven, Belgium
    Genomics 20:119-21. 1994
    ..PCR analysis based on genomic sequences, with DNA from both somatic cell hybrids, enabled us to map CACNL1A1, FGF6, D12S370, D12S38OE, D12S381E, and D12S382E distally to the 12p13 breakpoint and to VWF...
  3. ncbi request reprint Assignment of the gene for the human proliferating cell nucleolar protein P120 (NOL1) to chromosome 12p13 by fluorescence in situ hybridization and polymerase chain reaction with somatic cell hybrids
    M Baens
    Human Genome Laboratory, University of Leuven, Belgium
    Genomics 21:296-7. 1994
  4. ncbi request reprint Isolation and regional assignment of human chromosome 12p cDNAs
    M Baens
    Human Genome Analysis Laboratory, University of Leuven, Belgium
    Genomics 29:44-52. 1995
    ..Evidence was found for the duplication on 12p of a region containing a polymorphic simple sequence repeat and sequences of two different cDNAs...
  5. ncbi request reprint Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case
    I Wlodarska
    Center for Human Genetics, Flanders Interuniversity Institute for Biotechnology, Leuven, Belgium
    Cancer Res 56:2655-61. 1996
    ..In addition, the putative loss of wild-type function of CDKN1B and ETV6 could indicate a synergistic effect of both genes in the pathogenesis of this leukemia case...
  6. ncbi request reprint Quantitative trait loci for human muscle strength: linkage analysis of myostatin pathway genes
    W Huygens
    Research Center for Exercise and Health, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Belgium
    Physiol Genomics 22:390-7. 2005
    ..An additional set of valuable candidate genes that were not part of the myostatin pathway was found in the chromosome 12 and 13 genomic regions...
  7. ncbi request reprint Validation of 16S rDNA sequencing in microdissected bowel biopsies from Crohn's disease patients to assess bacterial flora diversity
    G De Hertogh
    Department of Morphology and Molecular Pathology, University Hospitals KULeuven, Belgium
    J Pathol 209:532-9. 2006
    ..Further study is needed to confirm these preliminary findings...
  8. ncbi request reprint Polymorphisms in the vitamin D receptor gene are associated with muscle strength in men and women
    A Windelinckx
    Research Center for Exercise and Health, Department of Biomedical Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, B 3001, Leuven, Belgium
    Osteoporos Int 18:1235-42. 2007
    ..Vitamin D receptor (VDR) polymorphisms have been associated with fracture risk and muscle strength, although evidence for the latter is limited and conflicting...