Sean X Zhang

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Enhancing molecular approaches for diagnosis of fungal infections
    Sean X Zhang
    Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 Wolfe Street, Meyer B1 193, Baltimore 21287, MD, USA
    Future Microbiol 8:1599-611. 2013
  2. pmc Actinomucor elegans as an emerging cause of Mucormycosis
    Aneela Mahmud
    Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School ofMedicine, Baltimore, Maryland, USA
    J Clin Microbiol 50:1092-5. 2012
  3. pmc Evaluation of CLSI agar dilution method and Trek Sensititre broth microdilution panel for determining antimicrobial susceptibility of Streptococcus pneumoniae
    Sean X Zhang
    Public Health Laboratories, Ontario Agency for Health Protection and Promotion, Toronto, Ontario, Canada
    J Clin Microbiol 49:704-6. 2011
  4. pmc Rapid identification of Cryptococcus neoformans var. grubii, C. neoformans var. neoformans, and C. gattii by use of rapid biochemical tests, differential media, and DNA sequencing
    Lisa McTaggart
    Medical Mycology, Ontario Public Health Laboratories, Ontario Agency for Health Protection and Promotion, Department ofLaboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
    J Clin Microbiol 49:2522-7. 2011
  5. pmc Cerebrospinal fluid (1,3)-β-D-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis
    Jennifer L Lyons
    Departments of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Microbiol 51:1285-7. 2013
  6. ncbi request reprint Epidemiology of Candida kefyr in patients with hematologic malignancies
    Simon F Dufresne
    Division of Infectious Disease, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Department of Microbiology and Immunology, Universite de Montreal, Montreal, Quebec, Canada
    J Clin Microbiol 52:1830-7. 2014
  7. doi request reprint Cunninghamella echinulata causing fatally invasive fungal sinusitis
    Robert E LeBlanc
    Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Diagn Microbiol Infect Dis 76:506-9. 2013
  8. pmc Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. nov. within the human pathogenic fungus Blastomyces dermatitidis
    Elizabeth M Brown
    Public Health Laboratories Toronto, Public Health Ontario, Toronto, Ontario, Canada
    PLoS ONE 8:e59237. 2013
  9. doi request reprint Iatrogenic Exserohilum infection of the central nervous system: mycological identification and histopathological findings
    W Robert Bell
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 7093, USA
    Mod Pathol 26:166-70. 2013
  10. doi request reprint Ochroconis gallopava infection in a patient with chronic granulomatous disease: case report and review of the literature
    Zina Meriden
    Department of Pathology, Division of Infectious Disease, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Med Mycol 50:883-9. 2012

Collaborators

  • Karen C Carroll
  • Stefan Riedel
  • Judith E Karp
  • Robert D Stevens
  • David A Stevens
  • Deanna A Sutton
  • Robert E LeBlanc
  • Kieren A Marr
  • Lisa R McTaggart
  • Jennifer L Lyons
  • Simon F Dufresne
  • Julie B Trivedi
  • W Robert Bell
  • Elizabeth M Brown
  • Daniel M Harrison
  • Richard Lee
  • Zina Meriden
  • Aneela Mahmud
  • Susan E Richardson
  • Thomas A Warren
  • Trish M Perl
  • Dionysios Neofytos
  • Janet F Staab
  • Kit Lu
  • Christian Lavallée
  • Emily Sydnor
  • Deanna Cettomai
  • Elakkat D Gireesh
  • Tiffany Chang
  • David T Pearce
  • Lyle W Ostrow
  • Kiran T Thakur
  • Justin B Dalton
  • Henry Neumann
  • Chad M McCall
  • Li Chen
  • Sarah Karram
  • Dorlan J Kimbrough
  • John N Ratchford
  • Bryan R Smith
  • Donald E Low
  • Laura Tochen
  • Warda Memon
  • Lisa Steiner
  • Karen L Roos
  • Kathryn Villa
  • Nicole Kwiatkowski
  • Aruna Subramanian
  • Dennis Neofytos
  • Peter B Illei
  • Delicia Munfus-McCray
  • Howard M Lederman

Detail Information

Publications12

  1. ncbi request reprint Enhancing molecular approaches for diagnosis of fungal infections
    Sean X Zhang
    Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 Wolfe Street, Meyer B1 193, Baltimore 21287, MD, USA
    Future Microbiol 8:1599-611. 2013
    ..Advances of developing quantitative assays and RNA detection platforms may provide another avenue to further improve fungal diagnostics. ..
  2. pmc Actinomucor elegans as an emerging cause of Mucormycosis
    Aneela Mahmud
    Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School ofMedicine, Baltimore, Maryland, USA
    J Clin Microbiol 50:1092-5. 2012
    ..This report, along with the three previously reported cases, is convincing evidence that A. elegans is an emerging fungal pathogen capable of causing invasive mucormycosis in humans...
  3. pmc Evaluation of CLSI agar dilution method and Trek Sensititre broth microdilution panel for determining antimicrobial susceptibility of Streptococcus pneumoniae
    Sean X Zhang
    Public Health Laboratories, Ontario Agency for Health Protection and Promotion, Toronto, Ontario, Canada
    J Clin Microbiol 49:704-6. 2011
    ..While agar dilution was not an optimal method, the commercial panel appeared to be an acceptable method, with minor errors encountered for ceftriaxone, penicillin, and meropenem...
  4. pmc Rapid identification of Cryptococcus neoformans var. grubii, C. neoformans var. neoformans, and C. gattii by use of rapid biochemical tests, differential media, and DNA sequencing
    Lisa McTaggart
    Medical Mycology, Ontario Public Health Laboratories, Ontario Agency for Health Protection and Promotion, Department ofLaboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
    J Clin Microbiol 49:2522-7. 2011
    ..neoformans var. grubii, C. neoformans var. neoformans, and C. gattii. Based on these results, we describe a rapid identification algorithm for use in a microbiology laboratory to distinguish clinically relevant Cryptococcus spp...
  5. pmc Cerebrospinal fluid (1,3)-β-D-glucan detection as an aid for diagnosis of iatrogenic fungal meningitis
    Jennifer L Lyons
    Departments of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Microbiol 51:1285-7. 2013
    ..S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis and management of exposed patients...
  6. ncbi request reprint Epidemiology of Candida kefyr in patients with hematologic malignancies
    Simon F Dufresne
    Division of Infectious Disease, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Department of Microbiology and Immunology, Universite de Montreal, Montreal, Quebec, Canada
    J Clin Microbiol 52:1830-7. 2014
    ..C. kefyr appears to be increasing in HM patients, with prominent summer seasonality. These findings raise questions about the effect of antifungal agents and health care exposures (e.g., yogurt) on the epidemiology of this yeast. ..
  7. doi request reprint Cunninghamella echinulata causing fatally invasive fungal sinusitis
    Robert E LeBlanc
    Division of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Diagn Microbiol Infect Dis 76:506-9. 2013
    ..Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential. ..
  8. pmc Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. nov. within the human pathogenic fungus Blastomyces dermatitidis
    Elizabeth M Brown
    Public Health Laboratories Toronto, Public Health Ontario, Toronto, Ontario, Canada
    PLoS ONE 8:e59237. 2013
    ..Here, we examined the population genetic structure and geographic differentiation of the sexual, dimorphic fungus Blastomyces dermatitidis, the causative agent of blastomycosis...
  9. doi request reprint Iatrogenic Exserohilum infection of the central nervous system: mycological identification and histopathological findings
    W Robert Bell
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 7093, USA
    Mod Pathol 26:166-70. 2013
    ..This report describes the microbiological procedures and histopathological features for the identification of E. rostratum (a pigmented vascularly invasive fungi), the cause of a current nationwide outbreak of fatal fungal meningitis...
  10. doi request reprint Ochroconis gallopava infection in a patient with chronic granulomatous disease: case report and review of the literature
    Zina Meriden
    Department of Pathology, Division of Infectious Disease, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Med Mycol 50:883-9. 2012
    ..We also review the literature of human infections with Ochroconis to date, and discuss its microbiology to apprise both clinicians and laboratory personnel of this infrequently encountered but potentially aggressive pathogen...
  11. pmc Candida bracarensis bloodstream infection in an immunocompromised patient
    Thomas A Warren
    Department of Laboratory Medicine and Pathobiology, University of Toronto, and Division of Microbiology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Microbiol 48:4677-9. 2010
    ..The organism can be distinguished from C. glabrata by its white color on CHROMagar and by DNA sequence analysis using D1/D2 and internal transcribed spacer (ITS) primers...
  12. pmc Phylogeny and identification of Nocardia species on the basis of multilocus sequence analysis
    L R McTaggart
    Medical Mycology, Public Health Laboratories, Ontario Agency for Health Protection and Promotion, Toronto, Ontario, Canada
    J Clin Microbiol 48:4525-33. 2010
    ..5% and 99.5% of isolates, respectively, and would be more feasible for routine use in a clinical reference microbiology laboratory...