Research Topics
| Jonathan M ZenilmanSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Distinguishing importation from diversification of quinolone-resistant Neisseria gonorrhoeae by molecular evolutionary analysisMarcos Pérez-Losada
Department of Integrative Biology, Brigham Young University, Provo, UT, USA
BMC Evol Biol 7:84. 2007..We applied molecular evolutionary analyses to DNA sequences from 9 housekeeping genes and gyrA, parC and porB of 24 quinolone resistant N. gonorrhoeae (QRNG) and 24 quinolone sensitive isolates collected in Israel during 2000-2001...
Behavioral interventions--rationale, measurement, and effectivenessJonathan M Zenilman
Division of Infectious Diseases, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, B 3 North, Baltimore, MD 21224, USA
Infect Dis Clin North Am 19:541-62. 2005..There is a worldwide sexual hangup hampering HIV prevention efforts...
A longitudinal study of vaginal douching and bacterial vaginosis--a marginal structural modeling analysisRebecca M Brotman
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Am J Epidemiol 168:188-96. 2008..In the absence of a large randomized trial, these findings provide the best evidence to date for a risk of bacterial vaginosis associated with douching...
Lumbar puncture in HIV-infected patients with syphilis and no neurologic symptomsKhalil G Ghanem
Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Clin Infect Dis 48:816-21. 2009..The Centers for Disease Control and Prevention recommend certain criteria that warrant lumbar puncture. Here, we assess the performance of these criteria for detecting asymptomatic neurosyphilis (ANS)...
Antiretroviral therapy is associated with reduced serologic failure rates for syphilis among HIV-infected patientsKhalil G Ghanem
Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Clin Infect Dis 47:258-65. 2008..Our goal was to determine whether the degree of HIV-mediated immunosuppression and the use of highly active antiretroviral therapy impact syphilis serologic responses...
Effect of menses on clearance of Y-chromosome in vaginal fluid: implications for a biomarker of recent sexual activityRebecca M Brotman
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
Sex Transm Dis 37:1-4. 2010..In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples...
Plasma antibodies against Chlamydia trachomatis, human papillomavirus, and human herpesvirus type 8 in relation to prostate cancer: a prospective studySiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6132 A, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 16:1573-80. 2007..70; 95% CI, 0.52-0.95). As this study is the first, to our knowledge, to observe such an inverse association, similar additional studies are warranted...
Depression and HIV risk behaviors among patients in a sexually transmitted disease clinicHeidi E Hutton
Department of Psychiatry, Johns Hopkins School of Medicine, 550 N Broadway, Suite 203, Baltimore, MD 21205, USA
Am J Psychiatry 161:912-4. 2004..The authors' goal was to investigate the relationship between depression and HIV risk behaviors or sexually transmitted disease (STD) diagnosis at an urban STD clinic...
Sexually transmitted diseases and risk behaviors among pregnant women attending inner city public sexually transmitted diseases clinics in Baltimore, MD, 1996-2002Hope L Johnson
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room E8537, Baltimore, MD 21205, USA
Sex Transm Dis 34:991-4. 2007..To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics...
Sexually transmitted infections and adverse pregnancy outcomes among women attending inner city public sexually transmitted diseases clinicsHope L Johnson
Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Sex Transm Dis 38:167-71. 2011..We sought to characterize antenatal care patterns and determine whether LGTI are independently associated with preterm birth and/or low-birth weight among a high-risk public sexually transmitted diseases (STD) clinic population...
Rapid fluctuation of the vaginal microbiota measured by Gram stain analysisRebecca M Brotman
Department of Epidemiology and Preventive Medicine, Institute for Genome Sciences, University of Maryland School of Medicine, BioPark Building II, 801 West Baltimore Street, Baltimore, MD 21201, USA
Sex Transm Infect 86:297-302. 2010..The aetiology of bacterial vaginosis (BV) remains unknown...
Prevalence and risk factors for reproductive tract infections among women in rural VietnamVivian F Go
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Southeast Asian J Trop Med Public Health 37:185-9. 2006..Given the low prevalence STD in this area of Vietnam, clinical case management of women presenting with RTI symptoms should focus on treatment of the more common endogenous infections, candida and BV...
The effect of vaginal douching cessation on bacterial vaginosis: a pilot studyRebecca M Brotman
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Am J Obstet Gynecol 198:628.e1-7. 2008..The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial...
Findings associated with recurrence of bacterial vaginosis among adolescents attending sexually transmitted diseases clinicsRebecca M Brotman
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21224, USA
J Pediatr Adolesc Gynecol 20:225-31. 2007..There are limited data on recurrent BV in adolescents. A relationship between the frequency of BV recurrence and specific risk factors might shed light on the pathophysiology of BV and lead to targeted interventions...
Detection and quantification of Y-chromosomal sequences by real-time PCR using the LightCycler systemJohan H Melendez
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Sex Transm Dis 34:617-9. 2007
High HIV sexual risk behaviors and sexually transmitted disease prevalence among injection drug users in Northern Vietnam: implications for a generalized HIV epidemicVivian F Go
Infectious Diseases Program, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Acquir Immune Defic Syndr 42:108-15. 2006..HIV prevalence in Vietnam is currently concentrated among injection drug users (IDUs). The extent to which this core risk group represents a potential for broader HIV transmission to the general population is currently unknown...
Perceptions about sexual concurrency and factors related to inaccurate perceptions among pregnant adolescents and their partnersAndrea Swartzendruber
Department of Population, Family and Reproductive Health, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Sex Transm Dis 39:577-82. 2012....
Treatment of syphilis in HIV-infected subjects: a systematic review of the literatureLeah J Blank
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Sex Transm Infect 87:9-16. 2011..The optimal antimicrobial regimen to treat syphilis in HIV-infected subjects remains controversial...
Foreskin inflammation is associated with HIV and herpes simplex virus type-2 infections in Rakai, UgandaKristine E Johnson
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, USA
AIDS 23:1807-15. 2009..We assessed foreskin inflammation associated with HIV and herpes simplex virus type 2 (HSV-2) in circumcised men...
Plasma antibodies against Trichomonas vaginalis and subsequent risk of prostate cancerSiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6138, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 15:939-45. 2006..As this study is the first, to our knowledge, to investigate associations between T. vaginalis serology and prostate cancer, additional studies are necessary before conclusions can be made...
Fluoroquinolone-resistant Neisseria gonorrhoeae: the inevitable epidemicKhalil G Ghanem
Division of Infectious Diseases, Johns Hopkins University, Bayview Medical Center, 4940 Eastern Avenue, B3 North, Suite 352, Baltimore, MD 21224, USA
Infect Dis Clin North Am 19:351-65. 2005..The loss of fluoroquinolones limits available oral regimens to a single CDC-recommended antibiotic, cefixime. Oral, inexpensive, single-dose alternatives are needed to ensure continued therapeutic success...
Recent herpes simplex virus type 2 infection and the risk of human immunodeficiency virus type 1 acquisition in IndiaSteven J Reynolds
Division of Infectious Diseases, School of Medicine, Baltimore, Maryland 21205, USA
J Infect Dis 187:1513-21. 2003..81 for recent incident HSV-2. Recent incident HSV-2 infection was associated with the highest risk of HIV-1 in this study, which suggests that prevention of HSV-2 infection may reduce the risk of HIV-1 acquisition...
The role of speculum and bimanual examinations when evaluating attendees at a sexually transmitted diseases clinicRameet H Singh
Divisions of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224
Sex Transm Infect 83:206-10. 2007..With the advent of molecular techniques, self-collected specimens without a clinician's examination are often adequate to detect common genital infections...
Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologiesJulie A Giles
Division of Allergies and Infectious Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Infect Dis 189:2085-93. 2004..gonorrhoeae in settings in which nonculture diagnostic methods are used...
The importance of a multifaceted approach to characterizing the microbial flora of chronic woundsAnne Han
Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Wound Repair Regen 19:532-41. 2011..Collectively, these data provide new insights into the identity, organization, and behavior of bacteria in chronic wounds. Such information may provide important clues to effective future strategies in wound healing...
Burden of Clostridium difficile-associated diarrhea in a long-term care facilityAlison M Laffan
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21224, USA
J Am Geriatr Soc 54:1068-73. 2006..To describe the incidence and prevalence of Clostridium difficile-associated diarrhea (CDAD) in a long-term care facility (LTCF)...
Procalcitonin as a marker for the detection of bacteremia and sepsis in the emergency departmentStefan Riedel
Dept of Pathology, The Johns Hopkins University, Baltimore, MD 21224, USA
Am J Clin Pathol 135:182-9. 2011..The positive predictive value was 17% and the negative predictive value 98% compared with blood cultures. Procalcitonin is a useful marker to rule out sepsis and systemic inflammation in the ED...
Generalizability of STD screening in urban emergency departments: comparison of results from inner city and urban sites in Baltimore, MarylandSupriya D Mehta
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Sex Transm Dis 30:143-8. 2003..However, assessing population characteristics is necessary to develop targeted screening methods and clinical algorithms and to improve participation of patients and program sustainability...
Why do women douche? A longitudinal study with two analytic approachesRebecca M Brotman
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21224
Ann Epidemiol 18:65-73. 2008..Although vaginal douching is associated with several adverse outcomes, the reasons why women douche have not been studied prospectively...
Neurosyphilis in a clinical cohort of HIV-1-infected patientsKhalil G Ghanem
Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
AIDS 22:1145-51. 2008..To describe the risk factors, clinical presentation, and long-term follow up of patients enrolled in a clinical cohort of HIV-infected patients who were diagnosed and treated for neurosyphilis...
Reassessing a large-scale syphilis epidemic using an estimated infection dateChristina M Schumacher
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Sex Transm Dis 32:659-64. 2005..CONCLUSIONS: Lag-time bias may be present when using epidemic curves based on report dates. Health departments should consider using an estimated infection date...
Barriers to reproductive tract infection (RTI) care among Vietnamese women: implications for RTI control programsVivian F Go
Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, 615 North Wolfe Street, Room E7133, Baltimore, MD 21205, USA
Sex Transm Dis 29:201-6. 2002..Vietnamese women may be especially vulnerable to reproductive tract infections (RTIs) and their biological and social sequelae. Few data are available on the prevalence of and health-seeking behavior for RTIs among women in Vietnam...
Polymerase chain reaction detection of Y chromosome sequences in vaginal fluid: preliminary studies of a potential biomarker for sexual behaviorJonathan M Zenilman
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Sex Transm Dis 32:90-4. 2005..Self-reported measures of sexual behavior are subject to nontrivial reporting biases...
The estimated magnitude and direct hospital costs of prosthetic joint infections in the United States, 1997 to 2004Matthew Hellmann
Division of Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21224 2780, USA
J Arthroplasty 25:766-71.e1. 2010..The nearly doubled number of prosthetic joint infection-related hospitalizations may have been caused by an increased implant rate, changes in patient population, implant procedures, or causative organisms...
Molecular microbiology: new dimensions for cutaneous biology and wound healingJo M Martin
Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
J Invest Dermatol 130:38-48. 2010....
Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentrationSiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
J Urol 175:1937-42. 2006..Further studies are warranted to replicate study findings and determine host and infection characteristics associated with large PSA increases...
Which patients first? Setting priorities for antiretroviral therapy where resources are limitedLaura J McGough
Department of Infectious Diseases, Johns Hopkins Bayview Medical Center, 4940 Eastern Ave, B 3 North, Baltimore, MD 21224, USA
Am J Public Health 95:1173-80. 2005..We then describe current rationing mechanisms for ARVs...
The prevalence of psychiatric disorders in sexually transmitted disease clinic patients and their association with sexually transmitted disease riskEmily J Erbelding
Baltimore City Health Department, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Sex Transm Dis 31:8-12. 2004..Psychiatric disorders could limit the success of behavioral counseling strategies. We evaluated the prevalence of psychiatric disorders among sexually transmitted disease (STD) clinic patients and their association with STD risk...
Cost-effectiveness of five strategies for gonorrhea and chlamydia control among female and male emergency department patientsSupriya D Mehta
Department of Medicine, Division of Infectious Disease, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Sex Transm Dis 29:83-91. 2002....
NAAT-identified and self-reported gonorrhea and chlamydial infections: different at-risk population subgroups?Susan M Rogers
Program in Health and Behavior Measurement, Research Triangle Institute, Washington, DC 20036, USA
Sex Transm Dis 29:588-96. 2002....
Untreated gonococcal and chlamydial infection in a probability sample of adultsCharles F Turner
Program in Health and Behavior Measurement, Research Triangle Institute, 1615 M St NW, Washington, DC 20036, USA
JAMA 287:726-33. 2002..Development of nucleic acid amplification tests, such as the ligase chain reaction assay, provides new opportunities to estimate the prevalence of untreated infections in the population...
Porin variation among clinical isolates of Neisseria gonorrhoeae over a 10-year period, as determined by Por variable region typingDurrie L McKnew
Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
J Infect Dis 187:1213-22. 2003..The present study provides information about the diversity of Por in strains circulating in a single geographic region over time, illustrates the utility of a novel por typing method, and has implications for vaccine development...
Toward better control of sexually transmitted diseasesEmily J Erbelding
N Engl J Med 352:720-1. 2005
Genetic typing of the porin protein of Neisseria gonorrhoeae from clinical noncultured samples for strain characterization and identification of mixed gonococcal infectionsFreyja Lynn
Division of Bacterial, Allergenic, and Parasitic Products, Center for Biologics Evaluation and Research, Bethesda, Maryland, USA
J Clin Microbiol 43:368-75. 2005..Methods that utilize direct clinical samples and can identify mixed infections may contribute significantly to studies of host immunity, gonococcal epidemiology, and pathogenesis...
Modeling a syphilis outbreak through space and time using the Bayesian maximum entropy approachDionne C Gesink Law
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, USA
Ann Epidemiol 16:797-804. 2006..The BME approach was useful for quantitatively and qualitatively describing the spatial development and spread of syphilis. Our results are specific to Baltimore; however, the BME approach is generalizable to other settings and diseases...
"Getting AIDS: not in my back yard." Results from a national knowledge, attitudes and practices surveyDaniel Chemtob
Department of Tuberculosis and AIDS, Public Health Services, Ministry of Health, Jerusalem, Israel
Isr Med Assoc J 8:610-4. 2006..Therefore, general population-based surveys of sexual behaviors among young adults may be useful for guiding prevention policy. To the best of our knowledge, the present survey is the first one among Israeli adults ever published...
Analysis of vaginal acetic acid in patients undergoing treatment for bacterial vaginosisAmjad N Chaudry
Osmetech plc, Crewe, UK
J Clin Microbiol 42:5170-5. 2004..This provides further evidence that the measurement of vaginal acetic acid by headspace analysis with conducting polymer sensors is a valid alternative to present tests for the diagnosis of BV...
Condom effectiveness for reducing transmission of gonorrhea and chlamydia: the importance of assessing partner infection statusLee Warner
National Center for HIV, STD and TB Prevention, Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Epidemiol 159:242-51. 2004..73). Restricting analyses to participants with known exposure to infected partners provides a feasible and efficient mechanism for reducing confounding from differential exposure to infected partners in condom effectiveness studies...
Chlamydia trachomatis among patients infected with and treated for Neisseria gonorrhoeae in sexually transmitted disease clinics in the United StatesSheryl B Lyss
Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop E-46, Atlanta, Georgia 30333, USA
Ann Intern Med 139:178-85. 2003..CONCLUSION: The frequent presence of chlamydia among patients at STD clinics who received treatment for gonorrhea, including sex partners of gonorrhea-infected patients, supports continuing current recommendations for co-treatment...
Epidemiology of chlamydial infection, gonorrhea, and trichomoniasis in the United States--2005William C Miller
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, CB 7435, 2105F McGavran Greenberg, Chapel Hill, NC 27599 7435, USA
Infect Dis Clin North Am 19:281-96. 2005..Greater effort must be devoted to reducing this disparity and to understanding the underlying mechanisms of disease persistence in the United States...
A community-based study of hepatitis B infection and immunization among young adults in a high-drug-use neighborhood in New York CityBenny J Kottiri
Office of HIV AIDS, US Agency for International Development, 1300 Pennsylvania Avenue, NW, Washington, DC 20523, USA
J Urban Health 82:479-87. 2005..Whereas subsequent younger generations benefited from universal childhood hepatitis B immunization, this particular cohort of young adults who live in communities like Bushwick presents a unique group for prevention intervention...
The state of condom use education in a Texas community: is this the future?Jonathan M Zenilman
Sex Transm Dis 33:5. 2006
Seroprevalence and correlates of herpes simplex virus type 2 infection among young adults in a low-income minority neighborhoodPeter L Flom
J Infect Dis 191:818-20; author reply 820-1. 2005
Congenital syphilis in immigrants--are politics and nativism driving us in reverse?Jonathan M Zenilman
Sex Transm Dis 35:344-5. 2008
