Research Topics
| S L ZegerSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
Research Grants
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Detail Information
Publications
On time series analysis of public health and biomedical dataScott L Zeger
Department of Biostatistics, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Annu Rev Public Health 27:57-79. 2006..S. cities on concentrations of particulate air pollution. Time series methods are necessary to make valid inferences from data by accounting for the correlation among repeated responses over time...
Exposure measurement error in time-series studies of air pollution: concepts and consequencesS L Zeger
Johns Hopkins University, School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 108:419-26. 2000..Finally, we summarize open questions regarding measurement error and suggest the kind of additional data necessary to address them...- Multivariate continuation ratio models: connections and caveatsP J Heagerty
Department of Biostatistics, University of Washington, Seattle 98195, USA
Biometrics 56:719-32. 2000..Finally, we illustrate the proposed methodology by analyzing psychological testing data previously summarized by TenHave and Uttal (1994, Applied Statistics 43, 371-384) and Guo and Lin (1994)... - Trends in air pollution and mortality: an approach to the assessment of unmeasured confoundingHolly Janes
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Epidemiology 18:416-23. 2007..5 and mortality at the local scale. If the association at the national scale is set aside, there is little evidence of an association between 12-month exposure to PM2.5 and mortality... - Are the acute effects of particulate matter on mortality in the National Morbidity, Mortality, and Air Pollution Study the result of inadequate control for weather and season? A sensitivity analysis using flexible distributed lag modelsLeah J Welty
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Am J Epidemiol 162:80-8. 2005.... - Mortality in the Medicare population and chronic exposure to fine particulate air pollution in urban centers (2000-2005)Scott L Zeger
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Environ Health Perspect 116:1614-9. 2008..5 microm in aerodynamic diameter (PM(2.5)) because few studies have been carried out and the cohorts have not been representative... - Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994J M Samet
Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
N Engl J Med 343:1742-9. 2000..Although these findings have helped lead to a tightening of air-quality standards, their validity with respect to public health has been questioned... - Community health survey in an urban African-American neighborhood: distribution and correlates of elevated blood pressureL R Bone
The Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205, USA
Ethn Dis 10:87-95. 2000..These data indicate the need for focused interventions to enhance hypertension maintenance of care and adherence to treatment... - Hierarchical bivariate time series models: a combined analysis of the effects of particulate matter on morbidity and mortalityFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, 615 N Wolfe Street, The Johns Hopkins University, Baltimore, MD 21205 3179, USA
Biostatistics 5:341-60. 2004..We illustrate this prediction using New York as an example... - Treatment effects of maternal micronutrient supplementation vary by percentiles of the birth weight distribution in rural NepalJoanne Katz
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 2103, USA
J Nutr 136:1389-94. 2006..Future analytic approaches to estimating benefits of maternal supplementation on birth weight should examine whether there is a constant or variable treatment effect across the distribution of birth weight... - Seasonal analyses of air pollution and mortality in 100 US citiesRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 6125 North Wolfe Street, Baltimore, MD 21205, USA
Am J Epidemiol 161:585-94. 2005..These results provide useful information for understanding particle toxicity and guiding future analyses of particle constituent data... - Quantitative methods for tracking cognitive change 3 years after coronary artery bypass surgerySarah J E Barry
Department of Biostatistics, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Ann Thorac Surg 79:1104-9. 2005..Software to implement the methods in the R statistical package is available from the authors at http://www.biostat.jhsph.edu/sbarry/software/ATSrcode.pdf... - Smooth quantile ratio estimation with regression: estimating medical expenditures for smoking-attributable diseasesFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, The Johns Hopkins University Baltimore, MD 21205 3179, USA
Biostatistics 6:505-19. 2005..Using a simulation study, we compare frequentist properties of two-part regression SQUARE with maximum likelihood estimators for the log-transformed expenditures... - Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseasesFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
JAMA 295:1127-34. 2006..5 microm in aerodynamic diameter [PM2.5]) is limited. Results from the new national monitoring network for PM2.5 make possible systematic research on health risks at national and regional scales... - Revised analyses of the National Morbidity, Mortality, and Air Pollution Study: mortality among residents of 90 citiesFrancesca Dominici
Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
J Toxicol Environ Health A 68:1071-92. 2005..The findings of the updated analysis with regard to spatial heterogeneity across the 90 cities were unchanged from the original analyses... - On the equivalence of case-crossover and time series methods in environmental epidemiologyYun Lu
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 2179, USA
Biostatistics 8:337-44. 2007..This equivalence also permits model checking for case-crossover data using standard log-linear model diagnostics... - Estimating treatment efficacy over time: a logistic regression model for binary longitudinal outcomesLeena Choi
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Stat Med 24:2789-805. 2005.... - Reproducible epidemiologic researchRoger D Peng
Biostatistics Department, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street E3535, Baltimore, MD 21205, USA
Am J Epidemiol 163:783-9. 2006..They also propose methods for reproducible research and implement them by use of a case study in air pollution and health... - Particulate air pollution and mortality in the United States: did the risks change from 1987 to 2000?Francesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 166:880-8. 2007..The methodology presented can be used to track the health effects of air pollution routinely on regional and national scales... - New problems for an old design: time series analyses of air pollution and healthJonathan M Samet
Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD 21205, USA
Epidemiology 14:11-2. 2003 - Emergency admissions for cardiovascular and respiratory diseases and the chemical composition of fine particle air pollutionRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Environ Health Perspect 117:957-63. 2009..5) (particulate matter <or= 2.5 microm in aerodynamic diameter) as the indicator. Evidence regarding the toxicity of the chemical components of the PM(2.5) mixture is limited... - Phenotype of frailty: characterization in the women's health and aging studiesKaren Bandeen-Roche
Department of Biostatistics, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Gerontol A Biol Sci Med Sci 61:262-6. 2006..This article evaluates the cross-validity, criterion validity, and internal validity in the Women's Health and Aging Studies (WHAS) of a discrete measure of frailty recently validated in the Cardiovascular Health Study (CHS)... - On the use of generalized additive models in time-series studies of air pollution and healthFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 3179, USA
Am J Epidemiol 156:193-203. 2002..The authors found that pooled NMMAPS estimates were very similar under the first and third methods but were biased upward under the second method... - Coarse particulate matter air pollution and hospital admissions for cardiovascular and respiratory diseases among Medicare patientsRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
JAMA 299:2172-9. 2008..5) have been studied extensively over the last decade. Evidence concerning the health risks of the coarse fraction of greater than 2.5 microm and 10 microm or less in aerodynamic diameter (PM10-2.5) is limited... - National maps of the effects of particulate matter on mortality: exploring geographical variationFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21205 3179, USA
Environ Health Perspect 111:39-44. 2003.... - Airborne particulate matter and mortality: timescale effects in four US citiesFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 157:1055-65. 2003..These analyses provide additional evidence that associations between particle indexes and mortality do not imply only an advance in the timing of death by a few days for frail individuals... 
An approach to checking case-crossover analyses based on equivalence with time-series methodsYun Lu
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Epidemiology 19:169-75. 2008..It is therefore important to perform model-checking in time-stratified case-crossover analyses rather than assume the estimator is unbiased...- Does the effect of PM10 on mortality depend on PM nickel and vanadium content? A reanalysis of the NMMAPS dataFrancesca Dominici
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21215, USA
Environ Health Perspect 115:1701-3. 2007..They found that average concentrations of nickel or vanadium in PM2.5 (PM with aerodynamic diameter < 2.5 microm) positively modified the lag-1 day association between PM10 and all-cause mortality... - Latent class model diagnosisE S Garrett
Oncology Center, Division of Biostatistics, Johns Hopkins University School of Medicine, 550 North Broadway, Baltimore, Maryland 21205, USA
Biometrics 56:1055-67. 2000..Simulations and a psychiatric example are presented to demonstrate the effective use of these methods... - Association between executive attention and physical functional performance in community-dwelling older womenM C Carlson
School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Gerontol B Psychol Sci Soc Sci 54:S262-70. 1999..This study examined whether executive attentional abilities were uniquely associated with the performance of complex, instrumental activities of daily living (IADLs) in cognitively intact and physically high-functioning older women... - Modelling disease progression in terms of exposure historyK Bandeen-Roche
Department of Biostatistics, Johns Hopkins University, Baltimore, MD 21205, USA
Stat Med 18:2899-916. 1999..We illustrate our methodology using data from a longitudinal epidemiologic investigation of the effects of amateur boxing on neuropsychologic function... - Cognition 6 years after surgical or medical therapy for coronary artery diseaseOla A Selnes
Department of Neurology, Baltimore, MD 21205 1910, USA
Ann Neurol 63:581-90. 2008..Long-term cognitive decline after CABG has been reported, but without appropriate control subjects, it is not known whether this decline is specific to CABG or related to other factors such as cerebrovascular disease... - Subjective memory symptoms in surgical and nonsurgical coronary artery patients: 6-year follow-upGuy M McKhann
Johns Hopkins University School of Medicine, Baltimore, Maryland 21218, USA
Ann Thorac Surg 87:27-34. 2009.... - Temperature and mortality in 11 cities of the eastern United StatesFrank C Curriero
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 155:80-7. 2002..The model developed in this analysis is potentially useful for projecting the consequences of climate-change scenarios and offering insights into susceptibility to the adverse effects of weather... - The evaluation of multiple surrogate endpointsJ Xu
Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland, USA
Biometrics 57:81-7. 2001..Markov chain Monte Carlo is implemented to estimate model parameters. The methodology is illustrated with an analysis of data from a schizophrenia clinical trial... - Statin use and neurologic morbidity after coronary artery bypass grafting: A cohort studyM A Koenig
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neurology 73:2099-106. 2009..Statin use before surgery has been associated with reduced morbidity and mortality after vascular surgery. The effect of preoperative statin use on stroke and encephalopathy after coronary artery bypass grafting (CABG) is unclear... - Zidovudine use in AIDS-free HIV-1-seropositive homosexual men in the Multicenter AIDS Cohort Study (MACS), 1987-1989N M Graham
Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland
J Acquir Immune Defic Syndr 4:267-76. 1991..No important differences were found in demographic or major clinical variables between clinical trial participants and zidovudine nonusers in this study... - Association between hypotension, low ejection fraction and cognitive performance in cardiac patientsRebecca F Gottesman
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Behav Neurol 22:63-71. 2010..The purpose of this study was to determine if cardiac ejection fraction (EF) is associated with cognitive performance, and whether this is modified by low blood pressure... - Delirium after coronary artery bypass graft surgery and late mortalityRebecca F Gottesman
Department of Neurology, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
Ann Neurol 67:338-44. 2010..The primary goal of this study was to determine whether patients with delirium after coronary artery bypass graft (CABG) surgery have higher long-term out-of-hospital mortality when compared with CABG patients without delirium... - Is there cognitive decline 1 year after CABG? Comparison with surgical and nonsurgical controlsG M McKhann
Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Neurology 65:991-9. 2005..Because most studies have not included comparable control groups, it remains unclear whether postoperative cognitive changes are specific to cardiopulmonary bypass, general aspects of surgery, or vascular pathologies of the aging brain... - The challenge of predicting demand for emergency department servicesMelissa L McCarthy
Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Acad Emerg Med 15:337-46. 2008..The objective was to develop methodology for predicting demand for emergency department (ED) services by characterizing ED arrivals... - The effectiveness of a community/academic health center partnership in decreasing the level of blood pressure in an urban African-American populationDavid M Levine
Sandtown-Winchester High Blood Pressure Control Program, The Johns Hopkins Schools of Medicine, Public Health and Nursing, Baltimore, Maryland 21205, USA
Ethn Dis 13:354-61. 2003..This study supports the use of community-based partnership efforts, and the utilization of indigenous health workers, to enhance the control of high blood pressure in a high-risk, African-American urban population... - Characterizing waiting room time, treatment time, and boarding time in the emergency department using quantile regressionRu Ding
Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Acad Emerg Med 17:813-23. 2010..The objective was to characterize service completion times by patient, clinical, temporal, and crowding factors for different phases of emergency care using quantile regression (QR)... - Do management strategies for coronary artery disease influence 6-year cognitive outcomes?Ola A Selnes
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ann Thorac Surg 88:445-454. 2009..Previous uncontrolled studies have suggested that there is late cognitive decline after coronary artery bypass grafting that may be attributable to use of the cardiopulmonary bypass pump... - Decreased incidence of cervical cancer in medicare-eligible California womenTerri L Cornelison
Kelly Gynecologic Oncology Service, Department of Gynecology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21210, USA
Obstet Gynecol 100:79-86. 2002.... - Ozone and short-term mortality in 95 US urban communities, 1987-2000Michelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, Conn 06511, USA
JAMA 292:2372-8. 2004..Although numerous time-series studies have estimated associations between day-to-day variation in ozone levels and mortality counts, results have been inconclusive... - Re: "On the use of generalized additive models in time-series studies of air pollution and health" and "Temperature and mortality in 11 cities of the eastern United States"Frank C Curriero
Am J Epidemiol 158:93-4. 2003 - Spatial and temporal variation in PM(2.5) chemical composition in the United States for health effects studiesMichelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, Connecticut, USA
Environ Health Perspect 115:989-95. 2007..Although numerous studies have demonstrated links between particulate matter (PM) and adverse health effects, the chemical components of the PM mixture that cause injury are unknown... - For the patient. Community health workers help to reduce high blood pressureDavid M Levine
Ethn Dis 13:403. 2003 - Neurologic intensive care resource use after brain tumor surgery: an analysis of indications and alternative strategiesWendy C Ziai
Johns Hopkins University School of Medicine, Batimore, MD, USA
Crit Care Med 31:2782-7. 2003..A prospective outcome study is required to determine feasibility, cost, and outcome of patients cared for in extended recovery and then transferred to a skilled nursing ward... - Factors associated with medical knowledge acquisition during internal medicine residencyFurman S McDonald
General Internal Medicine Hospital Internal Medicine, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN 55905, USA
J Gen Intern Med 22:962-8. 2007..Knowledge acquisition is a goal of residency and is measurable by in-training exams. Little is known about factors associated with medical knowledge acquisition... - Coronary artery bypass grafting baseline cognitive assessment: essential not optionalOla A Selnes
Ann Thorac Surg 83:374-6. 2007 - Associations of conference attendance with internal medicine in-training examination scoresFurman S McDonald
Division of General Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 83:449-53. 2008..To examine the association of medical knowledge acquisition with attendance at specific conference types during internal medicine residency...
Research Grants
- STATISTICS FOR LONGITUDINAL STUDIES OF MH SERVICESScott Zeger; Fiscal Year: 2001..The new methodologies can contribute to our understanding of mental disorders and patterns of care and ultimately to the improvement of mental health status. ..
- BIOSTATISTICS MENTAL HEALTH/PSYCHIATRY TRAINING PROGRAMScott Zeger; Fiscal Year: 2007..abstract_text> ..