Affiliation: Johns Hopkins University
Niu H, Cui P, Yee R, Shi W, Zhang S, Feng J, et al
. A Clinical Drug Library Screen Identifies Tosufloxacin as Being Highly Active against Staphylococcus aureus Persisters. Antibiotics (Basel). 2015;4:329-36 pubmed publisher
..Further studies are needed to evaluate tosufloxacin in animal models and to explain its unique activity against bacterial persisters. Our findings may have implications for improved treatment of persistent bacterial infections. ..
Yee R, Cui P, Shi W, Feng J, Zhang Y. Genetic Screen Reveals the Role of Purine Metabolism in Staphylococcus aureus Persistence to Rifampicin. Antibiotics (Basel). 2015;4:627-42 pubmed publisher
..These findings provide new insights into the mechanisms of persistence in S. aureus and provide novel therapeutic targets for developing more effective treatment for persistent infections due to S. aureus. ..
Niu H, Yee R, Cui P, Tian L, Zhang S, Shi W, et al
. Identification of Agents Active against Methicillin-Resistant Staphylococcus aureus USA300 from a Clinical Compound Library. Pathogens. 2017;6: pubmed publisher
..We ranked these new drug candidates according to their MICs against the MRSA strain USA300. Our findings may have implications for more effective treatment of MRSA infections. ..