Jianchun Xiao

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway
    J Xiao
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA Electronic address
    Neuroscience 268:128-38. 2014
  2. pmc The Toxoplasma MAG1 peptides induce sex-based humoral immune response in mice and distinguish active from chronic human infection
    Jianchun Xiao
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Microbes Infect 15:74-83. 2013
  3. pmc Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains
    Jianchun Xiao
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA
    J Neural Transm (Vienna) 120:1631-9. 2013
  4. pmc Anti-gluten immune response following Toxoplasma gondii infection in mice
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 7:e50991. 2012
  5. pmc Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells
    Jianchun Xiao
    Stanley Division of Developmental Neurovirology, Johns Hopkins School of Medicine, 600 N Wolfe Street, 1105 Blalock, Baltimore, MD 21287 4933, USA
    Infect Immun 79:1363-73. 2011
  6. doi Serological pattern consistent with infection with type I Toxoplasma gondii in mothers and risk of psychosis among adult offspring
    Jianchun Xiao
    The Stanley Division of Developmental Neurovirology, Johns Hopkins School of Medicine, 600 N Wolfe Street, 1105 Blalock, Baltimore, MD 21287 4933, USA
    Microbes Infect 11:1011-8. 2009
  7. doi Subunit and whole molecule specificity of the anti-bovine casein immune response in recent onset psychosis and schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, United States
    Schizophr Res 118:240-7. 2010
  8. pmc Chronic infection of Toxoplasma gondii downregulates miR-132 expression in multiple brain regions in a sex-dependent manner
    Y E Li
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Parasitology 142:623-32. 2015

Collaborators

Detail Information

Publications8

  1. pmc MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway
    J Xiao
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA Electronic address
    Neuroscience 268:128-38. 2014
    ..Our findings provide a possible mechanism for how the parasite contributes to the neuropathology of infection. ..
  2. pmc The Toxoplasma MAG1 peptides induce sex-based humoral immune response in mice and distinguish active from chronic human infection
    Jianchun Xiao
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Microbes Infect 15:74-83. 2013
    ..The results indicate that both MAG1 peptides may be used as a tool to differentiate active from inactive infection. It also may be considered in the design of potential vaccines in humans...
  3. pmc Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains
    Jianchun Xiao
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA
    J Neural Transm (Vienna) 120:1631-9. 2013
    ..No significant effects of type II infection were found in the NNS. These data may have implications for understanding the pathogenesis and heterogeneity of neurologic disturbances in toxoplasmosis. ..
  4. pmc Anti-gluten immune response following Toxoplasma gondii infection in mice
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 7:e50991. 2012
    ..gondii infection and sensitivity to dietary gluten, might be connected to produce the immune activation that is becoming an increasingly recognized pathology of psychiatric disorders...
  5. pmc Differential effects of three canonical Toxoplasma strains on gene expression in human neuroepithelial cells
    Jianchun Xiao
    Stanley Division of Developmental Neurovirology, Johns Hopkins School of Medicine, 600 N Wolfe Street, 1105 Blalock, Baltimore, MD 21287 4933, USA
    Infect Immun 79:1363-73. 2011
    ..These observed differences may explain some of the variation in the neurobiological effects of different strains of Toxoplasma on infected individuals...
  6. doi Serological pattern consistent with infection with type I Toxoplasma gondii in mothers and risk of psychosis among adult offspring
    Jianchun Xiao
    The Stanley Division of Developmental Neurovirology, Johns Hopkins School of Medicine, 600 N Wolfe Street, 1105 Blalock, Baltimore, MD 21287 4933, USA
    Microbes Infect 11:1011-8. 2009
    ..These findings suggest an influence of the parasite genotype on increased risk of psychosis and provide further support for a substantive role of Toxoplasma in the etiology of psychosis...
  7. doi Subunit and whole molecule specificity of the anti-bovine casein immune response in recent onset psychosis and schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, United States
    Schizophr Res 118:240-7. 2010
    ..The elevated IgG and unique patterns of antibody specificity to bovine casein among diagnostic groups provide a rationale for clinical trials to evaluate efficacies of dietary modifications in individuals with neuropsychiatric diseases...
  8. pmc Chronic infection of Toxoplasma gondii downregulates miR-132 expression in multiple brain regions in a sex-dependent manner
    Y E Li
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Parasitology 142:623-32. 2015
    ..However, the expressions of miR-132 or BDNF were poorly reflected by the density of T. gondii in brain areas. Our findings highlight the importance of investigating the miR-132-mediated neuronal function in mice infected with T. gondii. ..