Research Topics
| C L WuSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Correlation of postoperative pain to quality of recovery in the immediate postoperative periodChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
Reg Anesth Pain Med 30:516-22. 2005..It is unclear whether the severity of postoperative pain may affect patients' quality of recovery in the immediate postoperative period (within 2 weeks of surgery)...- Systematic review and analysis of postdischarge symptoms after outpatient surgeryChristopher L Wu
Department of Anesthesiology, Johns Hopkins University, Baltimore, MD, USA
Anesthesiology 96:994-1003. 2002 - Effect of postoperative epidural analgesia on morbidity and mortality after lung resection in Medicare patientsChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
J Clin Anesth 18:515-20. 2006..To perform an analysis of the Medicare claims database in patients undergoing lung resection to determine whether there is an association between postoperative epidural analgesia and mortality... - Effect of postoperative epidural analgesia on morbidity and mortality after total hip replacement surgery in medicare patientsChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Carnegie 280, 600 N Wolfe Street, Baltimore, MD 21287, USA
Reg Anesth Pain Med 28:271-8. 2003..systemic analgesia) on patient outcomes is unclear. Available randomized controlled trials (RCTs) have focused on the intraoperative period and not properly examined the effect of postoperative epidural analgesia (EA) on outcomes... - The effect of pain on health-related quality of life in the immediate postoperative periodChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Anesth Analg 97:1078-85, table of contents. 2003..IMPLICATIONS: Severity of postoperative pain may affect quality of life... - Postoperative cognitive function as an outcome of regional anesthesia and analgesiaChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Carnegie 280, 600 North Wolfe Street, Baltimore, MD 21287, USA
Reg Anesth Pain Med 29:257-68. 2004..We systematically reviewed the data from published studies to determine the effect of intraoperative neuraxial anesthesia versus general anesthesia on postoperative cognitive dysfunction and delirium... - Effect of postoperative epidural analgesia on morbidity and mortality following surgery in medicare patientsChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
Reg Anesth Pain Med 29:525-33; discussion 515-9. 2004.... - Gender and post-dural puncture headacheChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, MD 21287, USA
Anesthesiology 105:613-8. 2006..44-0.67). Although the authors found that nonpregnant female subjects seem to have a higher incidence of post-dural puncture headache than males, the etiology behind these findings is not clear from the current meta-analysis... - Efficacy of continuous local anesthetic infusion for postoperative pain after radical retropubic prostatectomyChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
Urology 66:366-70. 2005..To determine whether a subfascial continuous infusion of local anesthetic in patients undergoing radical retropubic prostatectomy would result in a reduction in postoperative opioid requirements and an improvement in pain scores... - Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids: a meta-analysisChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Anesthesiology 103:1079-88; quiz 1109-10. 2005.... - Correlation of postoperative epidural analgesia on morbidity and mortality after colectomy in Medicare patientsChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
J Clin Anesth 18:594-9. 2006..To examine, with a large database, the effect of postoperative epidural analgesia (vs systemic analgesia) on mortality after colectomy is unclear... - Perioperative stroke associated with postoperative epidural analgesiaC L Wu
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, NY, USA
J Clin Anesth 12:61-3. 2000..The patient recovered full neurologic function before discharge. Postoperative hypotension from epidural analgesia may be associated with stroke; however, a cause-and-effect relationship usually cannot be established with certainty... - The role of sympathetic nerve blocks in herpes zoster and postherpetic neuralgiaC L Wu
The Johns Hopkins Hospital, Department of Anesthesiology and Critical Care Medicine, Division of Pain Medicine, 550 N Broadway, Suite 301, Baltimore, MD 21205, USA
Pain 87:121-9. 2000..Current theories of the pathophysiology of PHN, the role of the sympathetic nervous system in herpes zoster and PHN, and published studies investigating use of sympathetic nerve blocks in herpes zoster and PHN are reviewed... - Correlation of postoperative epidural analgesia with morbidity and mortality following total knee replacement in Medicare patientsChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
Am J Orthop (Belle Mead NJ) 37:524-7. 2008..Postoperative epidural analgesia was not associated with lower incidence of mortality or major morbidity in Medicare patients who underwent elective total knee replacement... 
Treatment of acute postoperative painChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University and School of Medicine, Baltimore, MD 21287, USA
Lancet 377:2215-25. 2011..Use of specific analgesic techniques such as regional analgesia could improve patient outcomes. We also examine the development of new analgesic agents and treatment modalities and regimens for acute postoperative pain...- The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic reviewSpencer S Liu
Department of Anesthesiology, The Hospital of Special Surgery, and the Cornell Weill Medical Center, New York, New York, USA
Anesth Analg 105:789-808. 2007..We performed a systematic review to examine the effect of postoperative analgesia on patient-reported outcomes... - Effect of postoperative analgesia on major postoperative complications: a systematic update of the evidenceSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery and the Weill College of Medicine of Cornell University, New York, New York 10021, USA
Anesth Analg 104:689-702. 2007..Few individual clinical trials have had sufficient subject numbers to definitively determine the effects of postoperative analgesia on major outcomes... - Effects of perioperative central neuraxial analgesia on outcome after coronary artery bypass surgery: a meta-analysisSpencer S Liu
Department of Anesthesiology, Virginia Mason Medical Center and the University of Washington, Seattle, Washington 98111, USA
Anesthesiology 101:153-61. 2004..Perioperative central neuraxial analgesia may improve outcome after coronary artery bypass surgery due to attenuation of stress response and superior analgesia... - Comparison of ropivacaine-fentanyl patient-controlled epidural analgesia with morphine intravenous patient-controlled analgesia for perioperative analgesia and recovery after open colon surgeryRobert B Steinberg
Department of Anesthesiology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA 01199, USA
J Clin Anesth 14:571-7. 2002..002), but time until discharge was similar between groups. CONCLUSIONS: Ropivacaine-fentanyl PCEA provides superior analgesia, reduced opioid requirement, and more rapid recovery after colon surgery... - Midazolam premedication increases sedation but does not prolong discharge times after brief outpatient general anesthesia for laparoscopic tubal sterilizationM G Richardson
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Strong Memorial Hospital, New York 14642, USA
Anesth Analg 85:301-5. 1997..There were no differences in PACU time and time to discharge-readiness. In conclusion, midazolam premedication augments postoperative sedation in this population but does not prolong recovery times... - Strategies for postoperative pain managementAmanda K Brown
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Carnegie 280, 600 North Waite Street, Baltimore, MD 21287, USA
Best Pract Res Clin Anaesthesiol 18:703-17. 2004..Ideally, analgesic options should be incorporated into a multimodal approach to facilitate patient recovery after surgery... - Comparison of the postoperative analgesic efficacy of intravenous patient-controlled analgesia with tramadol to intravenous patient-controlled analgesia with opioidsJamie D Murphy
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA
J Opioid Manag 6:141-7. 2010..As such, the authors undertook a systematic review to compare the analgesic efficacy of IVPCA tramadol with that of IVPCA with opioids... - The analgesic effects of perioperative gabapentin on postoperative pain: a meta-analysisRobert W Hurley
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
Reg Anesth Pain Med 31:237-47. 2006..Gabapentin is an anticonvulsant that has been shown to be effective in the treatment of neuropathic and inflammatory pain in animal and human studies. The analgesic effect of its perioperative use has not been fully elucidated... - Pregabalin as a treatment for painful diabetic peripheral neuropathy: a meta-analysisRobert W Hurley
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
Reg Anesth Pain Med 33:389-94. 2008..We examined the effects of pregabalin on pain control, sleep disturbance, and the patient's global impression of change (PGIC) for the treatment of this disorder... - Survey of the utilization of regional and general anesthesia in a tertiary teaching hospitalMarie N Hanna
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University and School of Medicine, Baltimore, MD, USA
Reg Anesth Pain Med 34:224-8. 2009..We undertook a prospective observational study to determine the frequency and reasons for not choosing RA in cases for which it was considered an option... - Bevel direction and postdural puncture headache: a meta-analysisJeffrey M Richman
Department of Anesthesiology, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Neurologist 12:224-8. 2006..We performed a meta-analysis of available trials to determine if bevel direction during lumbar puncture would influence the incidence of PDPH... - Pulsed radiofrequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed radiofrequency of the intercostal nerves in the treatment of chronic postsurgical thoracic painSteven P Cohen
Department of Anesthesiology and Critical Care Medicine, Pain Management Division, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Pain Physician 9:227-35. 2006..To date, there are no studies comparing pulsed RF to more conventional therapeutic modalities for any pain condition... - Unrecognized contralateral intrapleural catheter: bilateral blockade may obscure detection of failed epidural catheterizationMichael A Cordone
Department of Anesthesiology and Critical Care, The Johns Hopkins University, School of Medicine Baltimore, Maryland, USA
Anesth Analg 104:735-7. 2007.... - Does neuraxial anesthesia reduce intraoperative blood loss? A meta-analysisJeffrey M Richman
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
J Clin Anesth 18:427-35. 2006..To perform a meta-analysis of available randomized controlled trials to determine if neuraxial anesthesia would decrease blood loss, compared with general anesthesia... - Does continuous peripheral nerve block provide superior pain control to opioids? A meta-analysisJeffrey M Richman
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
Anesth Analg 102:248-57. 2006..001). CPNB analgesia, regardless of catheter location, provided superior postoperative analgesia and fewer opioid-related side effects when compared with opioid analgesia... - Efficacy of postoperative epidural analgesia: a meta-analysisBrian M Block
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
JAMA 290:2455-63. 2003..CONCLUSION: Epidural analgesia, regardless of analgesic agent, location of catheter placement, and type and time of pain assessment, provided better postoperative analgesia compared with parenteral opioids... - Current treatment options for acute painAllan Gottschalk
Department of Anesthesiology and Critical Care Medicine, Meyer 8 134, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
Expert Opin Pharmacother 3:1599-611. 2002..A growing body of outcome studies demonstrates the long-term efficacy of this approach... - A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trialsSpencer S Liu
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, WA 98111, USA
Anesth Analg 101:1634-42. 2005..Other factors, such as unsuitable discharge criteria and limitations of meta-analysis, may explain this discrepancy... - The effect of intravenous opioid patient-controlled analgesia with and without background infusion on respiratory depression: a meta-analysisJessica A George
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
J Opioid Manag 6:47-54. 2010.... - Postoperative pain management in the elderly undergoing thoracic surgeryMarie N Hanna
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, The Johns Hopkins Hospital, Carnegie 280, 600 North Wolfe Street, Baltimore, MD 21287, USA
Thorac Surg Clin 19:353-61. 2009..Nevertheless, the available data suggest that use of regional analgesic techniques (ie, epidural and paravertebral catheters) is associated with a decrease in perioperative pulmonary complications... - Meta-analysis of the effect of extended-release epidural morphine versus intravenous patient-controlled analgesia on respiratory depressionShawn Sumida
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University and School of Medicine, Baltimore, Maryland, USA
J Opioid Manag 5:301-5. 2009..The authors have undertaken a meta-analysis to examine this issue... - Use of spinal anesthesia does not reduce intraoperative blood lossRobert P Wong
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
Urology 70:523-6. 2007..To determine whether the use of spinal anesthesia (versus general anesthesia) will result in lower intraoperative blood loss for radical retropubic prostatectomy... - The association of intraoperative neuraxial anesthesia on anticipated admission to the intensive care unitSandra C Kaufmann
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Blalock 1410, Baltimore, MD 21287, USA
J Clin Anesth 14:432-6. 2002..A causal relationship cannot be determined with this type of study and further research is needed to better understand this association... - Effect of post-operative analgesia on patient morbidityChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Best Pract Res Clin Anaesthesiol 16:549-63. 2002..A multimodal approach incorporating the use of epidural analgesia to control perioperative pathophysiology will facilitate the patient's recovery... - Effect of local anesthetics on patient recovery after transrectal biopsyC L Wu
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Urology 57:925-9. 2001..CONCLUSIONS: Injection of lidocaine lateral to the seminal vesicles before prostate biopsy did not diminish biopsy-associated pain... - Comparison of postoperative pain in patients receiving interscalene block or general anesthesia for shoulder surgeryChristopher L Wu
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, NY, USA
Orthopedics 25:45-8. 2002..006]). A higher percentage of patients who received regional anesthesia had a lower pain rating at 4 hours. Regional anesthesia for shoulder surgery decreases pain and facilitates recovery in the immediate postoperative period... - Regional techniques and outcome: what is the evidence?Marie N Hanna
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
Curr Opin Anaesthesiol 22:672-7. 2009.... - Analgesic effects of intravenous lidocaine and morphine on postamputation pain: a randomized double-blind, active placebo-controlled, crossover trialChristopher L Wu
Department of Anesthesiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Anesthesiology 96:841-8. 2002..0). CONCLUSIONS: Stump pain was diminished both by morphine and lidocaine, while phantom pain was diminished only by morphine, suggesting that the mechanisms and pharmacological sensitivity of stump and phantom pains are different... - Patient outcomes following ambulatory anesthesiaNina Deutsch
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Carnegie 280, 600 North Wolfe Street, Baltimore, MD 21287, USA
Anesthesiol Clin North America 21:403-15. 2003..As new anesthetic drugs and techniques continue to develop, outcomes research will continue to evolve in new directions, providing further information for improvements in patient care... - Where in the world is ASRA AcutePOP?Spencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, USA
Reg Anesth Pain Med 34:269-74. 2009..Development of a Web site and applications continues, and a demonstration is planned for the ASRA 2009 meeting... 
Risk assessment of obstructive sleep apnea in a population of patients undergoing ambulatory surgeryTracey L Stierer
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD, USA
J Clin Sleep Med 6:467-72. 2010....- Regional anesthesia and anticoagulationC L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
J Clin Anesth 13:49-58. 2001..Studies examining the use of neuraxial techniques in the presence of various anticoagulants are reviewed and evaluated in the context of the American Society of Regional Anesthesia consensus statements... - Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trialChristopher L Wu
Division of Pain Medicine, Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Anesthesiology 109:289-96. 2008..Stump and phantom pains are debilitating sequelae of amputations that are often resistant to treatment. The efficacy of pharmacologic therapies, including opioids and sodium channel blockers, for postamputation pain is uncertain... - Efficacy of periprostatic local anesthetic for prostate biopsy analgesia: a meta-analysisJeffrey M Richman
Department of Anesthesiology, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Urology 67:1224-8. 2006.... - Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized controlled trialsSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery and the Weill College of Medicine of Cornell University, New York, NY 10021, USA
J Am Coll Surg 203:914-32. 2006 - Epidural analgesia for postoperative painJeffrey M Richman
Department of Anesthesiology, The Johns Hopkins Hospital, Carnegie 280, 600 North Wolfe Street, Baltimore, MD 21287, USA
Anesthesiol Clin North America 23:125-40. 2005..In addition, the use of epidural analgesia should be evaluated on an individual basis because there are risks associated with this technique... - Does the routine prophylactic use of antiemetics affect the incidence of postdischarge nausea and vomiting following ambulatory surgery?: A systematic review of randomized controlled trialsAnil Gupta
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Anesthesiology 99:488-95. 2003 - Local administration of norepinephrine in the stump evokes dose-dependent pain in amputeesElaina E Lin
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Clin J Pain 22:482-6. 2006..Sympathectomy and adrenergic blockade should be explored in controlled clinical trials as therapeutic options in patients with postamputation pain... - An update on the treatment of postherpetic neuralgiaChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
J Pain 9:S19-30. 2008..These data may potentially help clinicians who attempt to provide analgesia in patients with PHN... - Difficult removal of a wire-reinforced epidural catheterHarold L Pierre
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
J Clin Anesth 15:140-1. 2003.... - Efficacy of bicarbonate in decreasing pain on intradermal injection of local anesthetics: a meta-analysisMarie N Hanna
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University and School of Medicine, Baltimore, MD 21287, USA
Reg Anesth Pain Med 34:122-5. 2009..We performed a meta-analysis of available trials investigating pain during intradermal injection of buffered local anesthetic preparations... - Optimizing postoperative analgesia: the use of global outcome measuresChristopher L Wu
Anesthesiology 97:533-4. 2002 - Acute post-surgical pain management: a critical appraisal of current practice, December 2-4, 2005James P Rathmell
University of Vermont College of Medicine, Burlington, VT 05403, USA
Reg Anesth Pain Med 31:1-42. 2006..This manuscript details those opinions and presents a critical analysis of the existing evidence supporting new and emerging techniques used to control postsurgical pain... - A lovely idea: forming an ASRA Acute Postoperative Pain (AcutePOP) databaseSpencer S Liu
Reg Anesth Pain Med 31:291-3. 2006 - Strengths and limitations of meta-analysisRobert D Stevens
J Cardiothorac Vasc Anesth 21:1-2. 2007 - The introduction of a regional anesthesia rotation: effect on resident education and operating room efficiencyJeffrey M Richman
J Clin Anesth 18:240-1. 2006 - Anticoagulation and neuraxial regional anesthesia: perspectivesDavid Bergqvist
Reg Anesth Pain Med 28:163-6. 2003