Research Topics
Species | Robert A WoodSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
The natural history of milk allergy in an observational cohortRobert A Wood
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Allergy Clin Immunol 131:805-12. 2013..There are few studies on the natural history of milk allergy. Most are single-site and not longitudinal, and these have not identified a means for early prediction of outcomes...
The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study populationJames E Gern
University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
BMC Pulm Med 9:17. 2009..This paper describes the study design, methods, and population of the Urban Environment and Childhood Asthma (URECA) study, which was established to investigate the immunologic causes of asthma among inner-city children...- An algorithm for treatment of patients with hypersensitivity reactions after vaccinesRobert A Wood
Johns Hopkins Hospital, CMSC 1102, 600 N Wolfe St, Baltimore, MD 21287, USA
Pediatrics 122:e771-7. 2008..We then include 3 cases of suspected allergic reactions to vaccines that have been referred to the Clinical Immunization Safety Assessment network to demonstrate the practical application of the algorithm... 
Accuracy of IgE antibody laboratory resultsRobert A Wood
Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Ann Allergy Asthma Immunol 99:34-41. 2007..However, it is not clear that quantitative sIgE results provided by different laboratories using different technologies are comparable...- The likelihood of remission of food allergy in children: when is the optimal time for challenge?Robert A Wood
Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Curr Allergy Asthma Rep 12:42-7. 2012..In this review, we focus on the optimal timing of oral food challenges, especially for patients with a known food allergy, to determine if the food allergy may have been outgrown... - Relationships among environmental exposures, cord blood cytokine responses, allergy, and wheeze at 1 year of age in an inner-city birth cohort (Urban Environment and Childhood Asthma study)Robert A Wood
Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 127:913-9.e1-6. 2011..The Urban Environment and Childhood Asthma study was established to investigate the immunologic and environmental causes of asthma in inner-city children... - Pediatric asthmaRobert A Wood
Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
JAMA 288:745-7. 2002 - Air filtration devices in the control of indoor allergensRobert A Wood
Johns Hopkins Hospital, 600 North Wolfe Street, CMSC 1102, Baltimore, MD 20287, USA
Curr Allergy Asthma Rep 2:397-400. 2002..The use of air cleaners for the management of allergic disease is reviewed in this article, and specific recommendations for their use are provided... - The clinical significance of low-level cat allergen exposureRobert A Wood
Johns Hopkins Hospital, 600 North Wolfe Street, CMSC 1102, Baltimore, MD 20287, USA
Curr Allergy Asthma Rep 2:395-6. 2002 - House dust mite and cockroach exposure: risk factors for asthmaRobert A Wood
Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Aerosol Med 17:165-8. 2004 - Room-specific characteristics of suburban homes as predictors of indoor allergen concentrationsTamara T Perry
Department of Pediatrics, Division of Allergy and Immunology, University of Arkansas for Medical Sciences College of Medicine, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
Ann Allergy Asthma Immunol 97:628-35. 2006..Room characteristics predicting indoor allergen exposure in suburban homes have not been clearly identified... - Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergyScott H Sicherer
Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Allergy Clin Immunol 125:1077-1083.e8. 2010..Immune features of infants with food allergy have not been delineated... - Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trialDavid M Fleischer
Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA
J Allergy Clin Immunol 131:119-27.e1-7. 2013..There are presently no available therapeutic options for patients with peanut allergy... - Oral immunotherapy for treatment of egg allergy in childrenA Wesley Burks
Department of Pediatrics, Duke University Medical Center, Durham, NC 27599 7220, USA
N Engl J Med 367:233-43. 2012..For egg allergy, dietary avoidance is the only currently approved treatment. We evaluated oral immunotherapy using egg-white powder for the treatment of children with egg allergy... - Mouse allergen exposure and mouse skin test sensitivity in suburban, middle-class children with asthmaElizabeth C Matsui
Department of Pediatrics, Johns Hopkins University, Johns Hopkins Hospital, CMSC 1102, 600 N Wolfe Street, Baltimore, MD 21287, USA
J Allergy Clin Immunol 113:910-5. 2004..Exposure to mouse allergen is prevalent in inner-city homes and is associated with an increased risk of mouse skin test sensitivity in inner-city children with asthma... - Protective effect of montelukast on lower and upper respiratory tract responses to short-term cat allergen exposureTamara T Perry
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Ann Allergy Asthma Immunol 93:431-8. 2004..02), with an odds ratio of 2.24 (95% CI, 1.16-4.32) in favor of montelukast. CONCLUSIONS: Montelukast has a protective effect against both lower and upper airway responses during exposure to high levels of cat allergen... - The natural history of persistent peanut allergyDara L Neuman-Sunshine
Department of Medicine, Division of Allergy and Clinical Immunology, The Johns Hopkins University School of Medicine, 600 North Wolfe St, Baltimore, MD 21287, USA
Ann Allergy Asthma Immunol 108:326-331.e3. 2012..Peanut allergy affects 1% of children, and for those with persistent disease, few data have been published on trends in peanut-specific immunoglobulin E (P-IgE) levels or the value of P-IgE in predicting reaction severity... - The safety and efficacy of sublingual and oral immunotherapy for milk allergyCorinne A Keet
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Allergy Clin Immunol 129:448-55, 455.e1-5. 2012..Oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) are potential therapies for food allergy, but the optimal method of administration, mechanism of action, and duration of response remain unknown... - A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergyJustin M Skripak
Department of Pediatrics, Division of Allergy and Immunology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 122:1154-60. 2008..Orally administered, food-specific immunotherapy appears effective in desensitizing and potentially permanently tolerizing allergic individuals... - Long-term immunologic effects of broad-spectrum aeroallergen immunotherapySusan L Limb
Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Md. 21224, USA
Int Arch Allergy Immunol 140:245-51. 2006..Broad-spectrum immunotherapy does not appear to affect the acquisition of new inhalant sensitivities... - Peanut allergy: recurrence and its managementDavid M Fleischer
Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA
J Allergy Clin Immunol 114:1195-201. 2004..On the basis of these findings, we now recommend that patients eat peanut frequently and carry epinephrine indefinitely until they have demonstrated ongoing peanut tolerance... - Adult asthma severity in individuals with a history of childhood asthmaSusan L Limb
Division of Allergy and Clinical Immunology, Bloomberg School of Public Health, Johns Hopkinds University, Baltimore, MD, USA
J Allergy Clin Immunol 115:61-6. 2005..Childhood asthma can have a range of outcomes in adulthood... - Peanut and tree nut allergy in childhoodJustin M Skripak
Division of Allergy and Immunology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Pediatr Allergy Immunol 19:368-73. 2008..This is of particular concern in adolescents and young adults, among whom life-threatening and fatal food allergy-related reactions are most common... - The relationship of allergen-specific IgE levels and oral food challenge outcomeTamara T Perry
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 114:144-9. 2004.... - Effect of environmental intervention on mouse allergen levels in homes of inner-city Boston children with asthmaWanda Phipatanakul
Department of Pediatrics, Division of Allergy and Immunology, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Ann Allergy Asthma Immunol 92:420-5. 2004..Recent studies have suggested that mouse allergen exposure and sensitization are common in urban children with asthma. The effectiveness of environmental intervention in reducing mouse allergen exposure has not been established... - Irreversible lung function deficits in young adults with a history of childhood asthmaSusan L Limb
Division of Allergy and Clinical Immunology, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA
J Allergy Clin Immunol 116:1213-9. 2005..Childhood spirometry, duration of asthma, methacholine sensitivity, and birth prematurity might identify such individuals at a young age... - Food protein-induced enterocolitis syndrome caused by solid food proteinsAnna Nowak-Wegrzyn
Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
Pediatrics 111:829-35. 2003..Infantile food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated gastrointestinal food hypersensitivity typically provoked by cow's milk or soy. Solid foods are rarely considered a cause... - Kinetics of mast cell, basophil, and oral food challenge responses in omalizumab-treated adults with peanut allergyJessica H Savage
Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD, USA
J Allergy Clin Immunol 130:1123-1129.e2. 2012.... - Urinary levels of triclosan and parabens are associated with aeroallergen and food sensitizationJessica H Savage
Johns Hopkins Division of Allergy and Clinical Immunology, Baltimore, MD 21224, USA
J Allergy Clin Immunol 130:453-60.e7. 2012..Endocrine-disrupting compounds (EDCs) have immune-modulating effects. We were interested in determining their association with allergic sensitization... - NIAID-sponsored 2010 guidelines for managing food allergy: applications in the pediatric populationA Wesley Burks
Division of Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
Pediatrics 128:955-65. 2011..To focus on those concerns, we describe here the guidelines most pertinent to the pediatric population... - Extension of food allergen specific IgE ranges from the ImmunoCAP to the IMMULITE systemsRobert G Hamilton
Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Ann Allergy Asthma Immunol 107:139-44. 2011..Quantitative measures of food specific IgE antibody using the Phadia ImmunoCAP method have documented value in the diagnosis of food allergy... - The natural history of tree nut allergyDavid M Fleischer
Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 116:1087-93. 2005..Although ideal cutoffs for challenge cannot be firmly recommended on the basis of these data, patients aged 4 years or older with all TN-IgE levels of 5 kU(A)/L or less should be considered for challenge... - Cockroach allergen exposure and sensitization in suburban middle-class children with asthmaElizabeth C Matsui
Department of Pediatrics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA
J Allergy Clin Immunol 112:87-92. 2003..Moreover, the data suggest that low-level cockroach exposure is a risk factor for cockroach sensitization... - A comparison of skin prick tests, intradermal skin tests, and specific IgE in the diagnosis of mouse allergyHemant P Sharma
Department of Pediatrics, Division of Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 121:933-9. 2008..However, it is unknown whether a positive skin test response or m-IgE result accurately identifies those with clinically relevant mouse sensitization... - The natural history of wheat allergyCorinne A Keet
Affiliations Department of Pediatrics, Division of Pediatric Allergy and Immunology, Johns Hopkins School of Medicine, Baltimore, Maryland 21227, USA
Ann Allergy Asthma Immunol 102:410-5. 2009..Wheat allergy is 1 of the most common food allergies in children, yet few data are available regarding its natural history... - Distribution of peanut allergen in the environmentTamara T Perry
Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 113:973-6. 2004..We were not able to detect airborne allergen in many simulated environments... - Suppression of the basophil response to allergen during treatment with omalizumab is dependent on 2 competing factorsDonald W Macglashan
Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
J Allergy Clin Immunol 130:1130-1135.e5. 2012..However, there were differences that provided additional insight into the nature of the cellular responses in allergic subjects... - The natural history of egg allergyJessica H Savage
Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Allergy Clin Immunol 120:1413-7. 2007..Egg allergy is very common, affecting 1% to 2% of children. It is generally thought that the majority of children with egg allergy develop tolerance in early childhood; however, this has not been examined in a large cohort with egg allergy... - The natural history of soy allergyJessica H Savage
Department of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Allergy Clin Immunol 125:683-6. 2010..4% of children. It is generally thought that the majority of children with soy allergy develop tolerance in early childhood; however, this has not been examined in a large cohort with soy allergy... - The natural progression of peanut allergy: Resolution and the possibility of recurrenceDavid M Fleischer
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Allergy Clin Immunol 112:183-9. 2003..CONCLUSIONS: Patients with a history of peanut allergy and peanut-IgE levels of 5 or less have at least a 50% chance of outgrowing their allergy. Recurrence of peanut allergy may occur but appears to be uncommon... - Comparison of the etiology of viral respiratory illnesses in inner-city and suburban infantsJames E Gern
Department of Pediatrics, University of Wisconsin, Madison, WI, USA
J Infect Dis 206:1342-9. 2012..Since inner-city infants have unique environmental exposures, we hypothesized that patterns of respiratory viral infections would also be distinct... - Personal and parental nativity as risk factors for food sensitizationCorinne A Keet
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21202, USA
J Allergy Clin Immunol 129:169-75.e1-5. 2012..Immigrants to developed countries have low rates of aeroallergen sensitization and asthma, but less is known about both food allergy and the role of parental immigration status... - The natural history of IgE-mediated cow's milk allergyJustin M Skripak
Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Allergy Clin Immunol 120:1172-7. 2007..Most studies have shown the prognosis of developing tolerance to cow's milk to be good, with most outgrowing their allergy by age 3 years... - Knowledge and practice of dust mite control by specialty careKaren A Callahan
Johns Hopkins University, School of Medicine, Baltimore, Maryland 21287, USA
Ann Allergy Asthma Immunol 90:302-7. 2003..Dust mites are the primary indoor allergen risk for increasing asthma attacks and morbidity. Adherence to allergen avoidance recommendations decreases bronchial reactivity and asthma morbidity... - Risk of oral food challengesTamara T Perry
Department of Pediatrics, Division of Allergy and Immunology, School of Medicine, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA
J Allergy Clin Immunol 114:1164-8. 2004..Given the benefits that result from a negative challenge, these risks are reasonable when challenges are performed under the guidance of an experienced practitioner in a properly equipped setting... - Managing food allergies in schools and campsKim Mudd
Johns Hopkins Division of Pediatric Allergy and Immunology, Johns Hopkins Hospital, 600 North Wolfe Street, CMSC 1105, Baltimore, MD 21287, USA
Pediatr Clin North Am 58:471-80, xi. 2011..The result is a dynamic strategy that meets the needs of a food-allergic child and promotes the development of a food-allergic adolescent... - Food allergy and anaphylaxisCorinne A Keet
Department of Pediatrics, Johns Hopkins School of Medicine, CMSC 1102, 600 North Wolfe Street, Baltimore, MD 21287, USA
Immunol Allergy Clin North Am 27:193-212, vi. 2007..Although several experimental medications promise to dramatically change the field of food allergy, none of these treatments are currently available outside of research settings... - Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributesWilliam J Savage
Department of Pathology, Division of Transfusion Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Transfusion 51:1716-22. 2011..Mechanisms of allergic transfusion reactions (ATRs) are not well understood. The aim of this study was to distinguish recipient-, donor-, and product-specific factors associated with ATRs... - A systematic review of the role of hydrolyzed infant formulas in allergy preventionTiffani Hays
Division of Pediatric Gastroenterology and Nutrition, Children s Nutrition Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21161, USA
Arch Pediatr Adolesc Med 159:810-6. 2005..To critically examine the published literature to determine whether feeding hydrolyzed infant formulas from birth has a role in allergy prevention... - Interferons modulate Fc epsilon RI-dependent production of autoregulatory IL-10 by circulating human monocytoid dendritic cellsTrong Le
Department of Pediatrics, Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
J Allergy Clin Immunol 123:217-23. 2009..Immature human blood monocytoid dendritic cells (mDCs) express high-affinity receptors for IgE (Fc epsilon RI), yet their exact function and regulation remain poorly understood... - The natural history of food allergyRobert A Wood
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Pediatrics 111:1631-7. 2003..This review provides an overview of the natural history of food allergy and provides specific information on the natural course of the most common childhood food allergies... - The efficacy of montelukast in the treatment of cat allergen-induced asthma in childrenWanda Phipatanakul
Department of Pediatrics, Division of Allergy and Immunology, Children's Hospital, Harvard Medical School, Boston, Mass 02115, USA
J Allergy Clin Immunol 109:794-9. 2002.... - Measurement of peptide-specific IgE as an additional tool in identifying patients with clinical reactivity to peanutsKirsten Beyer
Division of Pediatric Allergy and Immunology and Jaffe Institute for Food Allergy, The Mount Sinai School of Medicine, New York, NY 10029-6574, USA
J Allergy Clin Immunol 112:202-7. 2003..CONCLUSIONS: Determination of epitope recognition provides an additional tool to diagnose symptomatic peanut allergy, especially in children with peanut-specific IgE below diagnostic decision levels... - The diagnosis of allergy: why is it so difficult?Robert A Wood
Ann Allergy Asthma Immunol 91:1-2. 2003 - A jump start on allergen avoidance for expectant parentsTamara T Perry
Ann Allergy Asthma Immunol 91:507-9. 2003 - Skin testing: making the most of every prickRobert A Wood
Ann Allergy Asthma Immunol 88:347-9. 2002 - The medical effects of mold exposureRobert K Bush
University of Wisconsin-Madison, USA
J Allergy Clin Immunol 117:326-33. 2006..In addition, other purported mold-related illnesses and the data that currently exist to support them are carefully reviewed, as are the currently available approaches for the evaluation of both patients and the environment... - Food-specific immunotherapy: past, present, and futureRobert A Wood
J Allergy Clin Immunol 121:336-7. 2008 - Caution: the Phadia hazelnut ImmunoCAP (f17) has been supplemented with recombinant Cor a 1 and now detects Bet v 1-specific IgE, which leads to elevated values for persons with birch pollen allergyScott H Sicherer
J Allergy Clin Immunol 122:413-4, 414.e2. 2008 - Prospects for the prevention of allergy: a losing battle or a battle still worth fighting?Robert A Wood
Arch Pediatr Adolesc Med 160:552-4. 2006 - Irritant skin test reactions to common vaccinesRobert A Wood
J Allergy Clin Immunol 120:478-81. 2007 - The natural history of peanut allergy: Extending our knowledge beyond childhoodJessica H Savage
J Allergy Clin Immunol 120:717-9. 2007 - Peanut allergyElizabeth C Matsui
N Engl J Med 349:301-3; author reply 301-3. 2003 - Food manufacturing and the allergic consumer: accidents waiting to happenRobert A Wood
J Allergy Clin Immunol 109:920-2. 2002 - Author's response to accuracy of IgE antibody laboratory resultsRobert A Wood
Ann Allergy Asthma Immunol 100:288-9. 2008
Research Grants
- RESEARCH TRAINING IN PEDIATRIC ALLERGY AND IMMUNOLOGYRobert Wood; Fiscal Year: 2007..Clinical training focuses on Allergy and Immunology but also includes limited experience in Rheumatology, Pulmonology, and ENT, and is in accord with that specified by the Board of Allergy and Clinical Immunology. ..