Research Topics
| Christopher L WolfgangSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Role of fourth-generation troponin in predicting mortality in noncardiac surgeryChristopher L Wolfgang
Department of Surgery, Johns Hopkins University, Baltimore, Maryland, USA
JAMA Surg 148:12-3. 2013..Of the 200 million adults worldwide who undergo noncardiac surgery each year, more than 1 million will die within 30 days...
Evaluation of adjuvant chemoradiation therapy for ampullary adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative studyAmol K Narang
Department of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Radiat Oncol 6:126. 2011..We combined the experience of two institutions to better delineate which patients may benefit from adjuvant chemoradiation...- Predicting the risk of perioperative mortality in patients undergoing pancreaticoduodenectomy: a novel scoring systemRaghunandan Venkat
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Arch Surg 146:1277-84. 2011..To develop and validate a risk score to predict the 30- and 90-day mortality after a pancreaticoduodenectomy or total pancreatectomy on the basis of preoperative risk factors in a high-volume program... - Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreasMichael J Swartz
Department of Radiation Oncology and Molecular Radiation Sciences, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Hospital, Baltimore, MD 21231 2410, USA
Int J Radiat Oncol Biol Phys 76:839-44. 2010..Intraductal papillary mucinous neoplasms are mucin-producing cystic neoplasms of the pancreas. One-third are associated with invasive carcinoma. We examined the benefit of adjuvant chemoradiotherapy (CRT) for this cohort... - Adjuvant chemoradiation for pancreatic adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative studyCharles C Hsu
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Hospital, Baltimore, MD, USA
Ann Surg Oncol 17:981-90. 2010..Our goal was to examine efficacy of adjuvant CRT in resected pancreatic adenocarcinoma compared with surgery alone... - Liver-directed therapy for hepatic metastases in patients undergoing pancreaticoduodenectomy: a dual-center analysisMechteld C de Jong
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ann Surg 252:142-8. 2010..To analyze the perioperative and long-term outcomes of patients undergoing liver-directed therapy after pancreaticoduodenectomy in a large dual-center cohort of patients... - Re-evaluating the impact of tumor size on survival following pancreaticoduodenectomy for pancreatic adenocarcinomaMechteld C de Jong
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Surg Oncol 103:656-62. 2011..We sought to examine the association of size with outcomes following resection of pancreatic adenocarcinoma... - Peri-operative mortality and long-term survival after total pancreatectomy for pancreatic adenocarcinoma: a population-based perspectiveHari Nathan
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Surg Oncol 99:87-92. 2009..We sought to analyze peri-operative mortality and long-term survival following TP versus PP for pancreatic adenocarcinoma... - Total pancreatectomy for pancreatic adenocarcinoma: evaluation of morbidity and long-term survivalSushanth Reddy
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 22187, USA
Ann Surg 250:282-7. 2009..To analyze relative perioperative and long-term outcomes of patients undergoing total pancreatectomy versus pancreaticoduodenectomy... - Surgical management of solid-pseudopapillary neoplasms of the pancreas (Franz or Hamoudi tumors): a large single-institutional seriesSushanth Reddy
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Am Coll Surg 208:950-7; discussion 957-9. 2009..Solid-pseudopapillary neoplasms (SPNs) are rare pancreatic tumors with malignant potential. Clinicopathologic characteristics and outcomes of patients with SPN were reviewed... - Determining pattern of recurrence following pancreaticoduodenectomy and adjuvant 5-flurouracil-based chemoradiation therapy: effect of number of metastatic lymph nodes and lymph node ratioBolanle Asiyanbola
Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, Baltimore, MD 22187 6681, USA
J Gastrointest Surg 13:752-9. 2009..There are limited data on patterns of recurrence and factors associated with local recurrence following pancreaticoduodenectomy for pancreatic adenocarcinoma and adjuvant 5-flurouracil-based chemoradiation therapy... - Refining the definition of perioperative mortality following hepatectomy using death within 90 days as the standard criterionSkye C Mayo
Department of Surgery, School of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
HPB (Oxford) 13:473-82. 2011..To better define perioperative mortality, trends in the risk for death during the first 90 days after hepatectomy were assessed... - Impact of obesity on perioperative outcomes and survival following pancreaticoduodenectomy for pancreatic cancer: a large single-institution studySusan Tsai
Department of Surgery, Johns Hopkins Medical Institutions, 600N Wolfe Street, Baltimore, MD 21287, USA
J Gastrointest Surg 14:1143-50. 2010..To examine the effect of body mass index (BMI) on clinicopathologic factors and long-term survival in patients undergoing pancreaticoduodenectomy for pancreatic adenocarcinoma... - Resected pancreatic adenosquamous carcinoma: clinicopathologic review and evaluation of adjuvant chemotherapy and radiation in 38 patientsK Ranh Voong
Department of Radiation Oncology and Molecular Radiation Sciences, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Hospital, Baltimore, MD 21231 6681, USA
Hum Pathol 41:113-22. 2010..Treatment with adjuvant chemoradiation therapy is associated with improved survival. The proportion of squamous differentiation in resected pancreatic adenosquamous carcinoma specimens does not appear to impact overall survival... - The role of liver-directed surgery in patients with hepatic metastasis from a gynecologic primary carcinomaSarah I Kamel
Department of Surgery, Johns Hopkins University School of Medicine, Harvey 611, 600 N Wolfe Street, Baltimore, MD 21287, USA
World J Surg 35:1345-54. 2011..We sought to determine the safety and efficacy of liver-directed surgery for hepatic metastasis from gynecologic primaries... - Incidence and management of chyle leaks following pancreatic resection: a high volume single-center institutional experienceLia Assumpcao
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Gastrointest Surg 12:1915-23. 2008..We sought to identify possible risk factors associated with chyle leaks following pancreatic resection, as well as determine the natural history of this rare complication... - Management of patients with pancreatic adenocarcinoma: national trends in patient selection, operative management, and use of adjuvant therapySkye C Mayo
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Am Coll Surg 214:33-45. 2012..Advances in surgical technique and perioperative care have reduced perioperative mortality; however, temporal trends in perioperative morbidity and the use of adjuvant therapy on a population basis remain ill-defined... - Safety and efficacy of curative intent surgery for peri-ampullary liver metastasisMechteld C de Jong
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Surg Oncol 102:256-63. 2010..The management of patients with peri-ampullary liver metastasis remains controversial. We sought to assess the safety and efficacy of curative intent surgery for peri-ampullary liver metastasis... - Pancreatic resection of isolated metastases from nonpancreatic primary cancersSushanth Reddy
Department of Surgery, The Johns Hopkins University, 600 North Wolfe Street, Carnegie 681, Baltimore, Maryland 21287, USA
Ann Surg Oncol 15:3199-206. 2008..The goal of this study is to report the safety and efficacy of pancreatic resection for isolated metastatic cancers from nonpancreatic primary disease... - Hilar cholangiocarcinoma: tumor depth as a predictor of outcomeMechteld C de Jong
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Surg 146:697-703. 2011..The American Joint Committee on Cancer staging system for hilar cholangiocarcinoma may be inaccurate because the bile duct lacks discrete tissue boundaries... - Histopathologic basis for the favorable survival after resection of intraductal papillary mucinous neoplasm-associated invasive adenocarcinoma of the pancreasGeorge A Poultsides
Department of Surgery, Sidney Kimmel Cancer Center, Johns Hopkins Hospital, Baltimore, MD, USA
Ann Surg 251:470-6. 2010.... - Clinicopathologic analysis of ampullary neoplasms in 450 patients: implications for surgical strategy and long-term prognosisJordan M Winter
Department of Surgery, Johns Hopkins Medical Institutions, Halsted 610, 600 N Wolfe Street, Baltimore, MD 21287, USA
J Gastrointest Surg 14:379-87. 2010..We sought to examine the outcome of patients undergoing pancreaticoduodenectomy versus ampullectomy, as well as to identify factors predictive of lymph node metastasis in patients with ampullary neoplasms... - Risk factors for pancreatic leak after distal pancreatectomyHari Nathan
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Ann Surg 250:277-81. 2009..We sought to evaluate the incidence of and identify risk factors for the development of PL in patients undergoing distal pancreatectomy (DP) at a single high-volume institution... - Understanding surgical decision making in early hepatocellular carcinomaHari Nathan
The Johns Hopkins Hospital, 600 N Wolfe St, Harvey 611, Baltimore, MD 21287, USA
J Clin Oncol 29:619-25. 2011..We sought to quantify the impact of both clinical factors and surgeon specialty on surgical decision making in early HCC by using conjoint analysis... - National trends in the management and survival of surgically managed gallbladder adenocarcinoma over 15 years: a population-based analysisSkye C Mayo
Department of Surgery, The Johns Hopkins University School of Medicine, Harvey 611, 600 N Wolfe Street, Baltimore, MD 21287, USA
J Gastrointest Surg 14:1578-91. 2010..We sought to evaluate compliance with these recommendations and to assess trends in the management and survival of patients with GBA... 
Acinar cell carcinoma of the pancreas: an institutional series of resected patients and review of the current literatureAkhil K Seth
Department of Surgery, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Carnegie 683, Baltimore, MD 21287, USA
J Gastrointest Surg 12:1061-7. 2008..Acinar cell carcinoma (ACC) is a rare, malignant neoplasm with a generally poor prognosis. We report our institutional series of 14 patients with ACC to determine current guidelines for their evaluation and treatment...- Pancreatic surgery for the radiologist, 2011: an illustrated review of classic and newer surgical techniques for pancreatic tumor resectionChristopher L Wolfgang
Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA
AJR Am J Roentgenol 197:1343-50. 2011..CONCLUSION: CT interpretation should incorporate an understanding of current surgical techniques to provide surgeons with the information necessary for patient selection and preoperative planning... - Evaluating the impact of a single-day multidisciplinary clinic on the management of pancreatic cancerTimothy M Pawlik
Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD, USA
Ann Surg Oncol 15:2081-8. 2008..To evaluate the impact of a multidisciplinary clinic on the clinical care recommendations of patients with pancreatic cancer compared with the recommendations the patients received prior to review by the multidisciplinary tumor board... - Variations in referral patterns to high-volume centers for pancreatic cancerDavid C Chang
Department of Surgery, Johns Hopkins School of Medicine, 600 North Wolfe St, Baltimore, MD 21287, USA
J Am Coll Surg 209:720-6. 2009..This study noted trends in access to high-volume centers for pancreatic resection and identified gaps in improving access... - Choledochal cyst disease in children and adults: a 30-year single-institution experienceBarish H Edil
Department of Surgery, Johns Hopkins University, Baltimore, MD 21231, USA
J Am Coll Surg 206:1000-5; discussion 1005-8. 2008..Recognition and surgical treatment are important because of the significant longterm risks of developing cholangiocarcinoma. We report here the largest single-institution western experience with CC disease... - Palliative surgical management of patients with unresectable pancreatic adenocarcinoma: trends and lessons learned from a large, single institution experiencePeter J Kneuertz
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Gastrointest Surg 15:1917-27. 2011..We examined trends in the relative use of palliative bypass over time with an emphasis on identifying changes in surgical indications, type of bypass performed, as well as perioperative outcomes associated with surgical palliation... - Is resection of periampullary or pancreatic adenocarcinoma with synchronous hepatic metastasis justified?Ana Luiza Gleisner
Department of Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 22187 6681, USA
Cancer 110:2484-92. 2007..Specifically, the role of hepatic resection for metastatic periampullary or pancreatic adenocarcinoma remains controversial... - Is there a difference in survival between right- versus left-sided colon cancers?Robert A Meguid
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Ann Surg Oncol 15:2388-94. 2008..It is unclear whether patient prognosis varies by tumor location. In this study, we have compared the survival of right-and left-sided colon cancers in a longitudinal population-based database... - Solid-pseudopapillary neoplasm of the pancreas: spectrum of findings on multidetector CTSatomi Kawamoto
The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institutions, 601 North Caroline Street, Baltimore, MD 21287, USA
Clin Imaging 35:21-8. 2011..In this article we discuss and illustrate the spectrum of the appearances of this distinctive neoplasm on multidetector CT... - Analysis of fluorouracil-based adjuvant chemotherapy and radiation after pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas: results of a large, prospectively collected database at the Johns Hopkins HospitalJoseph M Herman
Department of Radiation Oncology and Molecular Radiation Sciences, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Hospital, Baltimore, MD, USA
J Clin Oncol 26:3503-10. 2008..To examine the efficacy of adjuvant chemoradiotherapy after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PC) in patients undergoing resection at Johns Hopkins Hospital (JHH; Baltimore, MD)... - Solid pseudopapillary neoplasms of the pancreasSushanth Reddy
John L Cameron Division of Surgical Oncology, The Sol Goldman Pancreatic Cancer Research Center, Department of Surgery, Johns Hopkins Medical Institutions, 606 Blalock Building, 600 North Wolfe Street, Baltimore, MD 21287, USA
Adv Surg 43:269-82. 2009..No consensus exists on an effective systemic therapy. There are no reliable predictors for disease-specific mortality or recurrence in the minority of patients who develop aggressive disease... - Trends in survival after surgery for cholangiocarcinoma: a 30-year population-based SEER database analysisHari Nathan
Department of Surgery, The Johns Hopkins University School of Medicine, Room 442, Cancer Research Building, 1650 Orleans Street, Baltimore, MD 21231 1000, USA
J Gastrointest Surg 11:1488-96; discussion 1496-7. 2007..We suggest that these trends are largely caused by developments in imaging technology, improvements in patient selection, and advances in surgical techniques... - Surgical management of giant Brunner's gland hamartoma: case report and literature reviewZoe A Stewart
Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Hospital, Baltimore, Maryland, USA
World J Surg Oncol 7:68. 2009..We report here an unusual case of a giant BGH that was not amenable to endoscopic or surgical local resection thus requiring a pancreaticoduodenectomy for extirpation. The relevant literature is discussed... - Does pancreatic duct stenting decrease the rate of pancreatic fistula following pancreaticoduodenectomy? Results of a prospective randomized trialJordan M Winter
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Gastrointest Surg 10:1280-90; discussion 1290. 2006..3). Internal pancreatic duct stenting does not decrease the frequency or the severity of postoperative pancreatic fistulas...