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| Sheila WestSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Three-year outcomes of the surgery for trichiasis, antibiotics to prevent recurrence trialFasika Woreta
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, 600 N Wolfe St, Baltimore, MD 21287, USA
Arch Ophthalmol 130:427-31. 2012..To determine whether treatment with oral azithromycin compared with topical tetracycline reduces the recurrence of trichiasis for up to 3 years following surgery for trichiasis...
Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparumPatricia Tabernero Estévez
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Malar J 10:104. 2011..In this study, antibodies to Plasmodium falciparum merozoite antigens were compared between blood and saliva samples from the same individuals in unlinked surveys conducted in Tanzania and The Gambia...- Diagnostic challenges of early Lyme disease: lessons from a community case seriesJohn Aucott
Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
BMC Infect Dis 9:79. 2009..When the characteristic rash, erythema migrans, is not recognized and treated, delayed manifestations of disseminated infection may occur. The accuracy of diagnosis and treatment of early Lyme disease in the community is unknown... - Number of years of annual mass treatment with azithromycin needed to control trachoma in hyper-endemic communities in TanzaniaSheila K West
Department of Opthalmology, Dana Center for Preventive Ophthalmology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
J Infect Dis 204:268-73. 2011..We determined the prevalence of trachoma and infection with Chlamydia trachomatis in communities after 3-7 years of annual mass treatment in Tanzania... 
Model of risk of cortical cataract in the US population with exposure to increased ultraviolet radiation due to stratospheric ozone depletionSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Am J Epidemiol 162:1080-8. 2005..Because of the high prevalence of cataract in older persons, at a 2003 cost of 3,370 dollars per cataract operation, this increase could represent an excess cost of 563 million dollars to 2.8 billion dollars...- Blinding trachoma: prevention with the safe strategySheila K West
Dana Center for Preventive Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Am J Trop Med Hyg 69:18-23. 2003..In the current climate of significant political and social momentum for trachoma control, the SAFE strategy is a safe bet to accomplish the elimination of blinding trachoma... - Trachoma: new assault on an ancient diseaseSheila K West
Dana Center for Preventive Ophthalmology, Johns Hopkins University School of Medicine, Wilmer Room 129, 600 North Wolfe Street, Baltimore, MD 21287, USA
Prog Retin Eye Res 23:381-401. 2004..While ongoing research to support the knowledge base for SAFE must continue to be a priority, the full implementation of SAFE is the best hope for countries to reduce the global burden of blindness from this preventable cause... - Intensive insecticide spraying for fly control after mass antibiotic treatment for trachoma in a hyperendemic setting: a randomised trialSheila K West
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, MD, USA
Lancet 368:596-600. 2006..We sought to determine whether insecticide spray intervention after mass antibiotic treatment could reduce trachoma and ocular infection with Chlamydia trachomatis in hyperendemic neighbourhoods in Tanzania... - Single-dose azithromycin prevents trichiasis recurrence following surgery: randomized trial in EthiopiaSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute and Department of Infectious Diseases, Johns Hopkins University, Baltimore, MD, USA
Arch Ophthalmol 124:309-14. 2006..Trichiasis recurrence following surgery is a serious problem for trachoma programs... - Gender equity and trichiasis surgery in the Vietnam and Tanzania national trachoma control programmesS West
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, MD, USA
Br J Ophthalmol 88:1368-71. 2004..To calculate the gender distribution of trichiasis cases in trachoma communities in Vietnam and Tanzania, and the gender distribution of surgical cases, to determine if women are using surgical services proportional to their needs... - Prevalence of pterygium in Latinos: Proyecto VERS West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA
Br J Ophthalmol 93:1287-90. 2009..Pterygium is a common corneal eye condition that can be disfiguring and may require surgery to avoid loss of vision. There are no population-based data on the prevalence or on risk factors among Latinos... - Do infants increase the risk of re-emergent infection in households after mass drug administration for trachoma?Sheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland 21287 9019, USA
Invest Ophthalmol Vis Sci 52:6040-2. 2011..The authors sought to determine whether infants aged <6 months are a source of re-emergent infection in their families after mass treatment in trachoma-endemic communities... - Epidemiology of cataract: accomplishments over 25 years and future directionsSheila West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Ophthalmic Epidemiol 14:173-8. 2007..From a public health standpoint, research that can identify ways to delay onset or progression, or achieve the holy grail of prevention of cataract, should remain a leading priority... - Compensatory strategy use identifies risk of incident disability for the visually impairedSheila K West
Dana Center for Preventive Ophthalmology and Lions Low Vision Center, Wilmer Eye Institute, The Johns Hopkins University, 600 N Wolfe Street, Rm 129, Baltimore, MD 21287, USA
Arch Ophthalmol 123:1242-7. 2005..Use of compensatory strategies may be a marker for preclinical disability... - How does visual impairment affect performance on tasks of everyday life? The SEE Project. Salisbury Eye EvaluationSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Ophthalmol 120:774-80. 2002..To determine the association between performance on selected tasks of everyday life and impairment in visual acuity and contrast sensitivity... - Change in function and spectacle-use 2 months after providing presbyopic spectacles in rural TanzaniaIlesh Patel
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Baltimore, MD 21287, USA
Br J Ophthalmol 94:685-9. 2010..To examine near vision spectacle retention and use, and changes in self-reported and performance-based near vision, 2 months after the provision of near vision spectacles... - Risk factors for Type II diabetes and diabetic retinopathy in a mexican-american population: Proyecto VERSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Am J Ophthalmol 134:390-8. 2002..Risk factors for type II diabetes and diabetic retinopathy were determined in a population-based study of Mexican-Americans... - Older drivers and failure to stop at red lightsSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, 600 North Wolfe Street, Baltimore, MD 2105, USA
J Gerontol A Biol Sci Med Sci 65:179-83. 2010..We determined the rate of running red traffic lights among older drivers and the relationship of failure to stop to measures of vision and cognition... - Looking forward to 20/20: a focus on the epidemiology of eye diseasesS K West
Dana Center for Preventive Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21287 9019, USA
Epidemiol Rev 22:64-70. 2000..Future epidemiologic research will continue to require a concerted, sustained, and multidisciplinary effort in order to contribute to the vision research agenda in the next century... - Trachoma and antibiotic use: the 'A' in SAFESheila West
Wilmer RM 129, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21205, USA
Expert Rev Anti Infect Ther 10:75-83. 2012..The antibiotics used, the effectiveness of this approach, and the challenges of antibiotic treatment of communities are discussed, concluding with a view towards the elimination of trachoma in the future... - Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal studySheila K West
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, MD, USA
Lancet 366:1296-300. 2005.... - Trachoma and ocular Chlamydia trachomatis were not eliminated three years after two rounds of mass treatment in a trachoma hyperendemic villageSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, JHU Hospital, 600 N Wolfe Street, Baltimore, MD 21205, USA
Invest Ophthalmol Vis Sci 48:1492-7. 2007..The rates of active trachoma and infection with C. trachomatis were determined in a community 3.5 years after two rounds of mass treatment with azithromycin... - Effect of trichiasis surgery on visual acuity outcomes in EthiopiaTinsay A Woreta
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA
Arch Ophthalmol 127:1505-10. 2009..To determine the effect of trichiasis surgery on visual acuity... - Surgery for Trichiasis, Antibiotics to prevent Recurrence (STAR) Clinical Trial methodologyEmily S West
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, MD 21205, USA
Ophthalmic Epidemiol 12:279-86. 2005..The primary outcome is trichiasis recurrence at one-year. Data from this trial will be critical in helping to determine future policy on antibiotic treatment for C. trachomatis following surgery... - Population-based study of presbyopia in rural TanzaniaAndrew G Burke
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, Maryland, USA
Ophthalmology 113:723-7. 2006..In addition, the 3-fold increased odds in town versus village dwellers was unexpected and suggests that research of other factors, including environmental factors, is warranted... - Azithromycin prevents recurrence of severe trichiasis following trichiasis surgery: STAR trialSheila West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Ophthalmic Epidemiol 14:273-7. 2007..This randomized, clinical trial determined if treating trichiasis surgical patients with oral azithromycin compared to usual care (topical tetracycline) resulted in a reduction in severe recurrence of trichiasis to one year... - Mass distribution of azithromycin for trachoma control is associated with short-term reduction in risk of acute lower respiratory infection in young childrenChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Pediatr Infect Dis J 31:341-6. 2012..We evaluated the effect of a single mass distribution of azithromycin for trachoma on the risk of acute lower respiratory infection (ALRI) during a 6-month period among young children living in 8 communities in rural Tanzania... - Urban and rural differences in older drivers' failure to stop at stop signsLisa Keay
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, United States
Accid Anal Prev 41:995-1000. 2009..In this cohort failure to stop at stop signs was not explained by poor vision or cognition. Conversely in urban areas, those who have visual field loss appear to be more cautious at stop signs... - Familial aggregation of hyperopia in an elderly population of siblings in Salisbury, MarylandRobert Wojciechowski
Johns Hopkins University School of Medicine and Public Health, Baltimore, Maryland, USA
Ophthalmology 112:78-83. 2005..Black men were significantly less likely to be hyperopic than white men, white women, or black women. CONCLUSIONS: Hyperopia appears to be under strong genetic control in this older population... - Design and baseline data of a randomized trial to evaluate coverage and frequency of mass treatment with azithromycin: the Partnership for Rapid Elimination of Trachoma (PRET) in Tanzania and The GambiaDianne Stare
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, MD, USA
Ophthalmic Epidemiol 18:20-9. 2011..The studies presented here evaluate the impact of coverage level and frequency of mass treatment with single dose azithromycin on trachoma and ocular C. trachomatis infection... - Impact of presbyopia on quality of life in a rural African settingIlesh Patel
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA
Ophthalmology 113:728-34. 2006..The high prevalence of presbyopia, and increased aging of the population in developing countries, suggests that the World Health Organization's Vision 2020 refraction agenda should place greater emphasis on presbyopia... - Age, sex, and cohort effects in a longitudinal study of trachomatous scarringMeraf A Wolle
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 50:592-6. 2009..To determine the 5-year incidence rate of scarring, and associated factors, in the population of Maindi, Tanzania... - Glaucoma and mobility performance: the Salisbury Eye Evaluation ProjectDavid S Friedman
Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USAaryland
Ophthalmology 114:2232-7. 2007..To determine the impact of glaucoma on mobility in a population-based cohort... - Glaucoma and quality of life: the Salisbury Eye EvaluationEllen E Freeman
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Ophthalmology 115:233-8. 2008..To examine whether glaucoma status or measures of visual function affected by glaucoma are associated with self-reported difficulty with vision-intensive tasks in a population-based study... - Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional dataAimee Teo Broman
Dana Center for Preventive Ophthalmology and the Glaucoma Service, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Invest Ophthalmol Vis Sci 49:66-76. 2008..To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies... - The impact of visual impairment and eye disease on vision-related quality of life in a Mexican-American population: proyecto VERAimee Teo Broman
Dana Center for Preventive Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 43:3393-8. 2002..Further work on the specific measures of vision associated with reported decreases in quality of life, such as visual field or contrast sensitivity, is warranted... - Cognitive and vision loss affects the topography of the attentional visual fieldShirin E Hassan
Lions Vision Center, Wilmer Eye Institute, Johns Hopkins University School ofMedicine, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 49:4672-8. 2008..The purposes of this study were to describe the AVF in a large sample of older drivers and identify demographic, cognitive, and vision factors associated with AVF performance and shape... - Measures of visual function and percentage of preferred walking speed in older adults: the Salisbury Eye Evaluation ProjectIlesh Patel
Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA
Invest Ophthalmol Vis Sci 47:65-71. 2006..Deficits in cognition also play an important role in predicting mobility performance... - Risk factors for postsurgical trichiasis recurrence in a trachoma-endemic areaEmily S West
Dana Center for Preventive Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 46:447-53. 2005..The World Health Organization recommends trichiasis surgery to prevent blindness caused by trachoma; however, recurrence is common. Risk factors for recurrence have not been widely studied, particularly in trachoma hyperendemic areas... - Household willingness to pay for azithromycin treatment for trachoma control in the United Republic of TanzaniaKevin D Frick
Johns Hopkins Bloomberg School of Public Health, Department of Health Policy and Management, 624 N Broadway, Baltimore, MD 21205 1901, USA
Bull World Health Organ 81:101-7. 2003..We tested for relationships between socioeconomic status, risk of trachoma, perceptions of the effects of azithromycin, and the household willingness to pay for future mass treatment with azithromycin... - Incidence and progression of lens opacities: effect of hormone replacement therapy and reproductive factorsEllen E Freeman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Epidemiology 15:451-7. 2004..We explored the associations of HRT and reproductive factors with the incidence and progression of lens opacities over a 2-year period... - The differential effect of ultraviolet light exposure on cataract rate across regions of the lensAlison G Abraham
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Invest Ophthalmol Vis Sci 51:3919-23. 2010..Further, it has been hypothesized that the lower nasal region of the lens is the most susceptible to damage by environmental ultraviolet light exposure... - Measures of visual function and their association with driving modification in older adultsEllen E Freeman
Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 47:514-20. 2006..Furthermore, these modifications to driving differed depending on what type of visual function was affected... - Chlamydial positivity of nasal discharge at baseline is associated with ocular chlamydial positivity 2 months following azithromycin treatmentEmily West Gower
Dana Center for Preventive Ophthalmology, 116 Wilmer Building, Johns Hopkins School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
Invest Ophthalmol Vis Sci 47:4767-71. 2006..Routes of transmission remain unclear. In this study, the relationship between Chlamydia trachomatis Amplicor-positive nasal discharge and Amplicor-positive ocular swabs was investigated (Amplicor; Roche, Indianapolis, IN)... - Cataract and barriers to cataract surgery in a US Hispanic population: Proyecto VERAimee Teo Broman
Dana Center for Preventive Ophthalmology, Johns Hopkins School of Medicine, Johns Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD 21287, USA
Arch Ophthalmol 123:1231-6. 2005..Language and financial barriers in this population impede access to surgery. Further work to remove these barriers and provide sight restoration is warranted among Hispanic individuals of Mexican descent living in the United States... - Racial variations in causes of vision loss in nursing homes: The Salisbury Eye Evaluation in Nursing Home Groups (SEEING) StudyDavid S Friedman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Arch Ophthalmol 122:1019-24. 2004..To determine the prevalence and causes of low vision in a large sample of nursing home residents... - Heritability of refractive error and familial aggregation of myopia in an elderly American populationRobert Wojciechowski
Bloomberg School of Public Health, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Invest Ophthalmol Vis Sci 46:1588-92. 2005..To determine the heritability of refractive error and the familial aggregation of myopia in an older population... - Determinants and heritability of intraocular pressure and cup-to-disc ratio in a defined older populationTa C Chang
Dana Center for Preventive Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ophthalmology 112:1186-91. 2005..004). CONCLUSIONS: In this elderly population, we found CDR to be highly heritable and IOP to be moderately heritable. On average, siblings of glaucoma patients had higher IOPs and larger CDRs than siblings of nonglaucomatous probands... - Measures of visual function and time to driving cessation in older adultsEllen E Freeman
Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Optom Vis Sci 82:765-73. 2005..It is important to identify the types of visual function loss that lead to driving cessation to better understand the relationship between vision and driving... - Mass treatment and the effect on the load of Chlamydia trachomatis infection in a trachoma-hyperendemic communityEmily S West
Dana Center for Preventive Ophthalmology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Invest Ophthalmol Vis Sci 46:83-7. 2005..Trachoma remains a leading cause of blindness. Determining the most effective antibiotic treatment strategy is essential for the success of country-based trachoma control programs... - Assessment of ocular exposure to visible light for population studiesDonald D Duncan
Johns Hopkins University, Applied Physics Laboratory, Laurel, MD, USA
Dev Ophthalmol 35:76-92. 2002..These data provide the basis for characterizing lifetime exposure for the general population and should permit exploration of the relationship between eye disease and cumulative ocular exposure to visible light... - Mass Distribution of Azithromycin for Trachoma Control Is Associated With Increased Risk of Azithromycin-Resistant Streptococcus pneumoniae Carriage in Young Children 6 Months After TreatmentChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland
Clin Infect Dis 56:1519-26. 2013..It is crucial that changes in antibiotic resistance patterns and their clinical significance in the treatment of severe pediatric infections be assessed in future MDA trials... - Association of mass treatment with azithromycin in trachoma-endemic communities with short-term reduced risk of diarrhea in young childrenChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Am J Trop Med Hyg 85:691-6. 2011..By the 3-6-month period, diarrhea incidence was comparable between groups. Thus, MDA was associated with a short-term reduction in diarrheal morbidity in children... - Prevalence of cataract and pseudophakia/aphakia among adults in the United StatesNathan Congdon
Wilmer Eye Institute, Wilmer 120, 600 N Wolfe Street, Baltimore, MD 21287, USA
Arch Ophthalmol 122:487-94. 2004..To determine the prevalence of cataract and pseudophakia/aphakia in the United States and to project the expected change in these prevalence figures by 2020... - Constant ocular infection with Chlamydia trachomatis predicts risk of scarring in children in TanzaniaMeraf A Wolle
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Ophthalmology 116:243-7. 2009..We propose to determine the 5-year incidence of scarring in children with a history of constant severe trachoma, constant infection, or both compared with children who had a history of neither... - Grating visual acuity using the preferential-looking method in elderly nursing home residentsDavid S Friedman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 43:2572-8. 2002..To assess the performance of two approaches to visual acuity testing in a group of nursing home residents with cognitive impairment. The study was a cross-sectional comparison of the effectiveness of two tests of visual acuity... - Driving status and risk of entry into long-term care in older adultsEllen E Freeman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Public Health 96:1254-9. 2006..Innovative strategies to improve transportation options for older adults should be considered... - The association between myopia and various subtypes of lens opacity: SEE (Salisbury Eye Evaluation) projectMargaret A Chang
Wilmer Eye Institute and the Dana Center for Preventive Ophthalmology, Johns Hopkins University Schools of Medicine and Public Health, Baltimore, Maryland 21287, USA
Ophthalmology 112:1395-401. 2005..Measures of association between posterior subcapsular opacity and myopia were stronger in the current study than have previously been found. Longitudinal studies to confirm the association are warranted... - Randomized trial of high dose azithromycin compared to standard dosing for children with severe trachoma in TanzaniaJ Peter Campbell
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, 600 N Wolfe St, Baltimore, MD 21205, USA
Ophthalmic Epidemiol 16:175-80. 2009..We compared the C. trachomatis infection rates at six weeks post-treatment of children randomized to 30 mg/kg single dose of azithromycin versus 20 mg/kg single dose of azithromycin... - Poor uptake of cataract surgery in nursing home residents: the Salisbury Eye Evaluation in Nursing Home Groups studyDavid S Friedman
Dana Center for Preventive Ophthalmology, The Wilmer Eye Institute, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Arch Ophthalmol 123:1581-7. 2005..To compare the uptake of cataract surgery in nursing homes in which assistance was provided in obtaining services with that in control homes... - Issues in defining and measuring facial cleanliness for national trachoma control programsRachel Zack
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Room 129, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA
Trans R Soc Trop Med Hyg 102:426-31. 2008..Additionally, behavior change programs in these districts in Tanzania should especially target families without tin roofs or latrines... - Knowledge of diabetic eye disease and vision care guidelines among Hispanic individuals in Baltimore with and without diabetesBeatriz Munoz
Wilmer Eye Institute, Johns Hopkins University, 600 N Wolfe St, Room 118, Baltimore, MD 21205, USA
Arch Ophthalmol 126:968-74. 2008..To determine gaps in knowledge and barriers to care for diabetic eye disease in Hispanic individuals in Baltimore, Maryland... - Poor sense of direction is associated with constricted driving space in older driversKathleen A Turano
Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Wilmer Room 129, Baltimore, MD 21205, USA
J Gerontol B Psychol Sci Soc Sci 64:348-55. 2009..The SBSOD score also showed a significant association with women's self-reported driving restriction. The findings emphasize the need to explore the role of psychological factors, and include gender, in driving studies and models... - Motion-detection threshold and measures of balance in older adults: the SEE ProjectEllen E Freeman
Department of Ophthalmology, Johns Hopkins University, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 49:5257-63. 2008..The aim of this study was to identify the visual factors associated with various levels of balance ability in a population-based study of older adults... - Visual and cognitive deficits predict stopping or restricting driving: the Salisbury Eye Evaluation Driving Study (SEEDS)Lisa Keay
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 50:107-13. 2009..To determine the visual and other factors that predict stopping or restricting driving in older drivers... - Driving cessation and driving limitation in glaucoma: the Salisbury Eye Evaluation ProjectPradeep Y Ramulu
Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA
Ophthalmology 116:1846-53. 2009..To determine if glaucoma is associated with driving limitation or cessation... - Racial differences in the prevalence of age-related macular degeneration: the Salisbury Eye Evaluation (SEE) ProjectSusan B Bressler
The Wilmer Eye Institute, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287 9228, USA
Arch Ophthalmol 126:241-5. 2008..To determine differences in the prevalence of age-related macular degeneration (AMD) and its fundus manifestations in a population-based sample of older black and white Americans... - Racial differences and other risk factors for incidence and progression of age-related macular degeneration: Salisbury Eye Evaluation (SEE) ProjectMargaret A Chang
Retina Division and Dana Center for Preventative Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 49:2395-402. 2008..To evaluate risk factors for the incidence and progression of age-related macular degeneration (AMD) in a racially heterogeneous, geriatric population... - Cortical, but not posterior subcapsular, cataract shows significant familial aggregation in an older population after adjustment for possible shared environmental factorsNathan Congdon
The Johns Hopkins University Schools of Medicine and Public Health, Baltimore, Maryland, USA
Ophthalmology 112:73-7. 2005..To quantify the risk for age-related cortical cataract and posterior subcapsular cataract (PSC) associated with having an affected sibling after adjusting for known environmental and personal risk factors... - Pattern of recurrence of trachomatous trichiasis after surgery surgical technique as an explanationShannath L Merbs
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Ophthalmology 112:705-9. 2005..To evaluate the pattern of recurrence of trachomatous trichiasis (TT) after bilamellar tarsal rotation surgery for trachoma... - Hormone replacement therapy, reproductive factors, and age-related macular degeneration: the Salisbury Eye Evaluation ProjectEllen E Freeman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Ophthalmic Epidemiol 12:37-45. 2005..To evaluate a potential relationship between hormone replacement therapy (HRT), reproductive factors and age-related macular degeneration (AMD)... - Incidence of cytomegalovirus (CMV) retinitis in second eyes of patients with the acquired immune deficiency syndrome and unilateral CMV retinitisJohn H Kempen
Department of Ophthalmology, The Johns Hopkins University School of Medicine, 550 North Broadway, Suite 700, Baltimore, MD 21205, USA
Am J Ophthalmol 139:1028-34. 2005..To evaluate the risk and risk factors for developing cytomegalovirus (CMV) retinitis in previously uninvolved second eyes among patients with unilateral CMV retinitis... - Visual acuity change and mortality in older adultsEllen E Freeman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Baltimore, MD 21250, USA
Invest Ophthalmol Vis Sci 46:4040-5. 2005..The goals of this study are to determine whether visual acuity loss increases the risk of dying and to examine whether depressive symptoms act as a mediator in this relationship... - Prevalence of age-related macular degeneration in a population-based sample of Hispanic people in Arizona: Proyecto VERBeatriz Munoz
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA
Arch Ophthalmol 123:1575-80. 2005..To report the prevalence of age-related macular degeneration (AMD) in a population-based sample of Hispanic individuals aged 50 years and older... - Mortality risk for patients with cytomegalovirus retinitis and acquired immune deficiency syndromeJohn H Kempen
Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 37:1365-73. 2003.... - A randomized trial of visual impairment interventions for nursing home residents: study design, baseline characteristics and visual lossSheila K West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21205, USA
Ophthalmic Epidemiol 10:193-209. 2003.... - Risk of vision loss in patients with cytomegalovirus retinitis and the acquired immunodeficiency syndromeJohn H Kempen
Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Arch Ophthalmol 121:466-76. 2003..To characterize the effect of cytomegalovirus (CMV) retinitis and its treatment on visual acuity in patients with the acquired immunodeficiency syndrome... - Antibiotic dosage in trachoma control programs: height as a surrogate for weight in childrenBeatriz Munoz
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 44:1464-9. 2003..The purposes of this study were to determine whether an accurate dose could be determined by using height as a surrogate for weight and whether a single model of height-based dosage would be applicable in more than one setting... - Visual field loss increases the risk of falls in older adults: the Salisbury eye evaluationEllen E Freeman
Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 48:4445-50. 2007..Falls are a serious and preventable problem in older adults. Impaired vision has been linked to risk of falls; however, the impact of deficits in specific components of vision on the risk of falls is not well known... - Divided visual attention as a predictor of bumping while walking: the Salisbury Eye EvaluationAimee Teo Broman
Department of Ophthalmology, The Johns Hopkins University, Baltimore, MD, USA
Invest Ophthalmol Vis Sci 45:2955-60. 2004..The purpose of this study was to determine the association between bumping while walking and divided visual attention, as measured by the useful field of view (UFOV)... - The impact of fish and shellfish consumption on age-related macular degenerationBonnielin K Swenor
Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA
Ophthalmology 117:2395-401. 2010..To determine the relationship between fish and shellfish consumption and age-related macular degeneration (AMD) status in the Salisbury Eye Evaluation (SEE) Study participants... - Prevalence and density-related concordance of three diagnostic tests for malaria in a region of Tanzania with hypoendemic malariaStephen E Schachterle
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Clin Microbiol 49:3885-91. 2011..falciparum parasite rate and parasite densities are highest. Real-time PCR is more sensitive and specific than RDT and microscopy in low-prevalence, low-parasite-density settings... - A cross-sectional survey of water and clean faces in trachoma endemic communities in TanzaniaMorgan Rog
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA
BMC Public Health 11:495. 2011..We aimed to assess the household and personal factors that affected water use and face washing practices in Kongwa, Tanzania... - Comparison of the Abbott m2000 RealTime CT Assay and the Cepheid GeneXpert CT/NG Assay to the Roche Amplicor CT Assay for Detection of Chlamydia trachomatis in Ocular Samples from TanzaniaLaura Dize
Johns Hopkins University, Baltimore, Maryland, USA
J Clin Microbiol 51:1611-3. 2013..46% (95% CI, 95.2% to 99.2%); GeneXpert sensitivity was 100% (95% CI, 90% to 100%), and specificity was 100% (95% CI, 98.1% to 100%). The m2000 and GeneXpert assays appear to perform as well as the Amplicor assay... - Computer-aided assessment of diagnostic images for epidemiological researchAlison G Abraham
Epidemiology Department, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
BMC Med Res Methodol 9:74. 2009..However, these systems have not been well utilized in research settings to improve the measurement of clinical endpoints. Reductions in bias through their use could have important implications for etiologic research... - Racial Differences in Lens Opacity Incidence and Progression: The Salisbury Eye Evaluation (SEE) StudyPhilip Storey
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland
Invest Ophthalmol Vis Sci 54:3010-8. 2013..To evaluate racial differences in nuclear and cortical lens opacity incidence and progression over a 2-year period in an older American population... - Blindness, visual impairment and the problem of uncorrected refractive error in a Mexican-American population: Proyecto VERBeatriz Munoz
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
Invest Ophthalmol Vis Sci 43:608-14. 2002..To report the prevalence of blindness and visual impairment and the contribution of uncorrected refractive error to visual loss, in a population-based sample of Mexican Americans aged 40 and older... - Visual and cognitive predictors of performance on brake reaction test: Salisbury eye evaluation driving studyLei Zhang
Ophthalmic Epidemiol 14:216-22. 2007..Only the IRS depends on vision. Persons in good physical condition may perform poorly on brake reaction tests if their vision or cognition is compromised... - Causes of blindness and visual impairment in a population-based sample of U.S. HispanicsJorge Rodriguez
Department of Ophthalmology, University of Arizona, Tucson, AZ, USA
Ophthalmology 109:737-43. 2002..Further work on gender-based obstacles to eye care in the Hispanic community may be warranted... - Relationship between trachoma and chronic and acute malnutrition in children in rural EthiopiaAndrew G Smith
Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, UT, USA
J Trop Pediatr 53:308-12. 2007..12-3.43), even after controlling for age, gender and infection status of other household members. Host factors including malnutrition may play a role in determining disease manifestations... - A prospective, population-based study of the role of visual impairment in motor vehicle crashes among older drivers: the SEE studyGary S Rubin
Institute of Ophthalmology, University College London, 11 43 Bath Street, London, UK
Invest Ophthalmol Vis Sci 48:1483-91. 2007..To determine the role of vision and visual attention factors in automobile crash involvement... - Is there an association between cataract surgery and age-related macular degeneration? Data from three population-based studiesEllen E Freeman
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9019, USA
Am J Ophthalmol 135:849-56. 2003..To determine whether cataract surgery is associated with an increased prevalence of age-related macular degeneration (AMD) in three independent population-based data sets... - The prevalence of open-angle glaucoma among blacks and whites 73 years and older: the Salisbury Eye Evaluation Glaucoma StudyDavid S Friedman
Dana Center for Preventive Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Ophthalmol 124:1625-30. 2006..To determine the prevalence of glaucoma among black and white persons 73 years and older... - Field evaluation of a rapid point-of-care assay for targeting antibiotic treatment for trachoma control: a comparative studyClaude-Edouard C Michel
Diagnostics Development Unit, Department of Haematology, University of Cambridge, Cambridge, UK
Lancet 367:1585-90. 2006..Additional studies should assess the use of the assay in the planning and monitoring of trachoma control activities... - Validity of a personal and family history of cataract and cataract surgery in genetic studiesHeidi Bowie
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Invest Ophthalmol Vis Sci 44:2905-8. 2003..CONCLUSIONS: Whereas accurate self and family histories for cataract surgery may be obtainable, it is difficult to ascertain cataract status accurately from history alone... - Strategies for control of trachoma: observational study with quantitative PCRAnthony W Solomon
London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
Lancet 362:198-204. 2003..Success of antibiotic distribution programmes could depend on these groups receiving effective treatment... - Which members of a community need antibiotics to control trachoma? Conjunctival Chlamydia trachomatis infection load in Gambian villagesMatthew J Burton
London School of Hygiene and Tropical Medicine, London, United Kingdom
Invest Ophthalmol Vis Sci 44:4215-22. 2003.... - Spatial clustering of ocular chlamydial infection over time following treatment, among households in a village in TanzaniaAimee Teo Broman
Department of Ophthalmology, The Johns Hopkins University, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 47:99-104. 2006.... - Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal studyMatthew J Burton
London School of Hygiene and Tropical Medicine, London, UK
Lancet 365:1321-8. 2005..We measured the effect of mass treatment on the conjunctival burden of Chlamydia trachomatis in a Gambian community with low to medium trachoma prevalence and investigated the rate, route, and determinants of re-emergent infection... - Mass treatment with single-dose azithromycin for trachomaAnthony W Solomon
Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
N Engl J Med 351:1962-71. 2004..Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is an important cause of blindness. Current recommended dosing intervals for mass azithromycin treatment for trachoma are based on a mathematical model...
Research Grants
- Cataract: Health Disparity for Older African-AmericansSheila West; Fiscal Year: 2006..These data will advance the goal of reducing health disparity in visual disability from cataract among older African Americans. ..
- Who drives safely? Visual/cognitive predictors in EldersSheila West; Fiscal Year: 2007..This study will provide critical data on the interactive role of vision, visual attention, and cognition in changing older persons driving behaviors, and the resulting effect on driver errors and risk of crashes. ..
- Latino Eye Health: A Communication Strategy for DiabetesSheila West; Fiscal Year: 2007..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. ..
- Yearly Mass Treatment C. Trachomatis: When Can We Stop?Sheila West; Fiscal Year: 2007....
- Yearly Mass Treatment C. Trachomatis: When Can We Stop?Sheila West; Fiscal Year: 2007..abstract_text> ..
- INTERVENTIONS FOR VISUAL LOSS IN NURSING HOME RESIDENTSSheila West; Fiscal Year: 2002..This trial will answer timely questions of the impact on the functional status of the most frail elderly of modest, potentially sustainable inputs into improving the appropriate utilization of eye care services. ..
- AMD AND RISK FACTORS IN A HISPANIC POPULATIONSheila West; Fiscal Year: 2003..Such data will advance our understanding of the magnitude of AMD in this ethnic group, and the way in which risk factors relate to AMD in different populations. ..
- TRIAL OF ANTIBIOTICS TO REDUCE RECURRENT TRICHIASISSheila West; Fiscal Year: 2005..abstract_text> ..