Chiming Wei

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint DNA damage and repair system in spinal cord ischemia
    Ruxian Lin
    Cardiothoracic Renal Research Program, Department of Surgery, University of Maryland School of Medicine, Baltimore, USA
    J Vasc Surg 37:847-58. 2003
  2. ncbi request reprint Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways
    Hong Liang Li
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, People s Republic of China
    Free Radic Biol Med 40:1756-75. 2006
  3. ncbi request reprint Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity
    Lili A Barouch
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Res 98:119-24. 2006
  4. ncbi request reprint New technology and clinical applications of nanomedicine: highlights of the second annual meeting of the American Academy of Nanomedicine (Part I)
    Chiming Wei
    Johns Hopkins University, Baltimore, Maryland 21205, USA
    Nanomedicine 2:253-63. 2006
  5. ncbi request reprint Nanomedicine and drug delivery
    Chiming Wei
    Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
    Med Clin North Am 91:863-70. 2007
  6. ncbi request reprint Highlights of the first annual meeting of the American Academy of Nanomedicine
    Chiming Wei
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nanomedicine 1:351-7. 2005
  7. ncbi request reprint From bench to bedside: successful translational nanomedicine: highlights of the Third Annual Meeting of the American Academy of Nanomedicine
    Chiming Wei
    Molecular Nanomedicine Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nanomedicine 3:322-31. 2007
  8. ncbi request reprint Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease
    Daqing Gao
    Department of Surgery, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    Am J Physiol Gastrointest Liver Physiol 287:G1070-7. 2004
  9. ncbi request reprint Increased mitochondrial reactive oxygen species production in newborn brain during hypoglycemia
    Jane E McGowan
    Department of Pediatrics, School of Medicine, The Johns Hopkins University, USA
    Neurosci Lett 399:111-4. 2006
  10. pmc The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cord
    Glen Roseborough
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Pathol 168:1443-51. 2006

Research Grants

Collaborators

Detail Information

Publications24

  1. ncbi request reprint DNA damage and repair system in spinal cord ischemia
    Ruxian Lin
    Cardiothoracic Renal Research Program, Department of Surgery, University of Maryland School of Medicine, Baltimore, USA
    J Vasc Surg 37:847-58. 2003
    ..We hypothesized that ischemia-reperfusion injury in spinal cord causes DNA damage manifested by 8-oxoG production and activates the DNA repair system involving hMYH, hOGG1, and hMSH2...
  2. ncbi request reprint Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways
    Hong Liang Li
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, People s Republic of China
    Free Radic Biol Med 40:1756-75. 2006
    ..These findings indicated that EGCG prevents the development of cardiac hypertrophy through ROS-dependent and -independent mechanisms involving inhibition of different intracellular signaling transductional pathways...
  3. ncbi request reprint Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity
    Lili A Barouch
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Res 98:119-24. 2006
    ..These data offer novel insights into potential mechanisms of myocardial dysfunction and early mortality in obesity...
  4. ncbi request reprint New technology and clinical applications of nanomedicine: highlights of the second annual meeting of the American Academy of Nanomedicine (Part I)
    Chiming Wei
    Johns Hopkins University, Baltimore, Maryland 21205, USA
    Nanomedicine 2:253-63. 2006
    ..We believe that nanomedicine research will develop rapidly in the future. The AANM invites basic and clinical researchers from the world to join this exciting research...
  5. ncbi request reprint Nanomedicine and drug delivery
    Chiming Wei
    Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
    Med Clin North Am 91:863-70. 2007
    ..The impedance biosensor is expected to find applications in monitoring cytokines in cancer, bone turnover markers in osteoporosis, and understanding neural-degenerative diseases...
  6. ncbi request reprint Highlights of the first annual meeting of the American Academy of Nanomedicine
    Chiming Wei
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nanomedicine 1:351-7. 2005
  7. ncbi request reprint From bench to bedside: successful translational nanomedicine: highlights of the Third Annual Meeting of the American Academy of Nanomedicine
    Chiming Wei
    Molecular Nanomedicine Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nanomedicine 3:322-31. 2007
    ..The meeting provided exciting information for nanomedicine clinical-related researches and strategy for further development of nanomedicine research which will be benefits to clinical practice...
  8. ncbi request reprint Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease
    Daqing Gao
    Department of Surgery, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    Am J Physiol Gastrointest Liver Physiol 287:G1070-7. 2004
    ..These findings raise the intriguing possibility that inherited or acquired differences in DNA repair enzyme activity may underlie some of the interindividual differences in fatty liver disease outcomes...
  9. ncbi request reprint Increased mitochondrial reactive oxygen species production in newborn brain during hypoglycemia
    Jane E McGowan
    Department of Pediatrics, School of Medicine, The Johns Hopkins University, USA
    Neurosci Lett 399:111-4. 2006
    ..Increased mitochondrial ROS production could result in alterations in brain structure and function due to oxidant injury to mitochondrial proteins and DNA or changes in oxidant-sensitive signal transduction pathways in brain...
  10. pmc The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cord
    Glen Roseborough
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Pathol 168:1443-51. 2006
    ....
  11. ncbi request reprint New advances in nanomedicine: diagnosis and preventive medicine
    Chiming Wei
    Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
    Med Clin North Am 91:871-9. 2007
    ....
  12. ncbi request reprint Genetic nanomedicine and tissue engineering
    Chiming Wei
    Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
    Med Clin North Am 91:889-98. 2007
    ....
  13. ncbi request reprint Selective decrease in the DNA base excision repair pathway in squamous cell cancer of the esophagus
    Pramod Bonde
    Cardiothoracic Renal Research Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Thorac Cardiovasc Surg 133:74-81. 2007
    ....
  14. ncbi request reprint Duodenal reflux leads to down regulation of DNA mismatch repair pathway in an animal model of esophageal cancer
    Pramod Bonde
    Cardiothoracic Renal Molecular Research Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Ann Thorac Surg 83:433-40; discussion 440. 2007
    ..We tested the effect of reflux, either alone or in combination with the human dietary mutagen methyl-n-amyl nitrosamine (MNAN), on DNA damage in adenocarcinoma and squamous cell cancer of the esophagus in a rat model...
  15. ncbi request reprint Impact of 24 h continuous hypothermic perfusion on heart preservation by assessment of oxidative stress
    Torin P Fitton
    The Johns Hopkins Medical Institution, Baltimore, MD, USA
    Clin Transplant 18:22-7. 2004
    ..We investigated continuous hypothermic perfusion (CHP), a new form of HP, and the mechanism of injury associated with hypothermic storage, by assessing functional outcome and OS after allotransplantation of canine hearts...
  16. ncbi request reprint Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha
    Zheqing Cai
    Vascular Program, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Cardiovasc Res 77:463-70. 2008
    ..We investigated whether hypoxia-inducible factor 1 alpha (HIF-1 alpha) plays a role in the acute phase of ischaemic preconditioning (IPC)...
  17. ncbi request reprint Attenuation of DNA damage in canine hearts preserved by continuous hypothermic perfusion
    Torin P Fitton
    Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ann Thorac Surg 80:1812-20. 2005
    ..We hypothesized that continuous hypothermic perfusion would allow for maintenance of cardiac function while attenuating myocardial DNA damage with respect to the current clinical practice of static preservation at 4 degrees C...
  18. ncbi request reprint Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways
    Hong Liang Li
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Beijing 100005, Peoples Republic of China
    Free Radic Biol Med 38:243-57. 2005
    ..These findings suggest that ISO prevents the development of cardiac hypertrophy through an antioxidant mechanism involving inhibition of different intracellular signaling transduction pathways...
  19. ncbi request reprint New technology and clinical applications of nanomedicine
    Lian Zuo
    Department of Cardiology, Emory University School of Medicine, 101 Woodruff Circle, WMB319, Atlanta, GA 30322, USA
    Med Clin North Am 91:845-62. 2007
    ..Toxicologic considerations also are discussed...
  20. ncbi request reprint Recent advances in basic and clinical nanomedicine
    K John Morrow
    Newport Biotechnology Consultants, 625 Washington Avenue, Newport, KY 41071, USA
    Med Clin North Am 91:805-43. 2007
    ..Site-specific targeted drug delivery and personalized medicine are just a few concepts that are on the horizon...
  21. ncbi request reprint beta(2)-Adrenergic stimulation attenuates left ventricular remodeling, decreases apoptosis, and improves calcium homeostasis in a rodent model of ischemic cardiomyopathy
    Steve Xydas
    Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Pharmacol Exp Ther 317:553-61. 2006
    ..We conclude that clenbuterol ameliorates EDPVR, apoptosis, and calcium homeostasis but does not have synergy with metoprolol in our model of ischemic HF...
  22. ncbi request reprint Nanomedicine in cancer treatment
    Tachung C Yih
    Department of Medical Engineering and Biomechanics, University of Texas at San Antonio, San Antonio, Texas, USA
    Nanomedicine 1:191-2. 2005
  23. ncbi request reprint Modeling and characterization of a nanoliter drug-delivery MEMS micropump with circular bossed membrane
    Tachung C Yih
    Department of Mechanical Engineering and Biomechanics, University of Texas at San Antonio, San Antonio, Texas 78249, USA
    Nanomedicine 1:164-75. 2005
    ..Integration of the function over 1 driving cycle and multiplication by the driving frequency provides the drug-delivery rate of the micropump...
  24. ncbi request reprint Quantum dots for robust and simple assays using single particles in nanodevices
    Peixuan Guo
    Purdue University, West hafayette, Indiada John Hopkins University, USA
    Nanomedicine 1:122-4. 2005

Research Grants5

  1. GROWTH AND DEATH OF VASCULAR SMOOTH MUSCLE CELLS
    Chiming Wei; Fiscal Year: 2002
    ..Aim 4. To determine the relationship of the p53 gene with p21-WAF gene and bcl-2 gene expression during NPS-induced apoptosis in VSMC isolated from IMA and SV. ..
  2. GROWTH AND DEATH OF VASCULAR SMOOTH MUSCLE CELLS
    Chiming Wei; Fiscal Year: 1999
    ..Aim 4. To determine the relationship of the p53 gene with p21-WAF gene and bcl-2 gene expression during NPS-induced apoptosis in VSMC isolated from IMA and SV. ..
  3. GROWTH AND DEATH OF VASCULAR SMOOTH MUSCLE CELLS
    Chiming Wei; Fiscal Year: 2000
    ..Aim 4. To determine the relationship of the p53 gene with p21-WAF gene and bcl-2 gene expression during NPS-induced apoptosis in VSMC isolated from IMA and SV. ..
  4. GROWTH AND DEATH OF VASCULAR SMOOTH MUSCLE CELLS
    Chiming Wei; Fiscal Year: 2001
    ..Aim 4. To determine the relationship of the p53 gene with p21-WAF gene and bcl-2 gene expression during NPS-induced apoptosis in VSMC isolated from IMA and SV. ..
  5. GROWTH AND DEATH OF VASCULAR SMOOTH MUSCLE CELLS
    Chiming Wei; Fiscal Year: 2002
    ..Aim 4. To determine the relationship of the p53 gene with p21-WAF gene and bcl-2 gene expression during NPS-induced apoptosis in VSMC isolated from IMA and SV. ..