Research Topics
Species | Chiming WeiSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
DNA damage and repair system in spinal cord ischemiaRuxian Lin
Cardiothoracic-Renal Research Program, Department of Surgery, University of Maryland School of Medicine, Baltimore, USA
J Vasc Surg 37:847-58. 2003..CONCLUSION: This study has shown, for the first time, the rapid expression of DNA damage-repair processes associated with spinal cord ischemia and subsequent reperfusion...- Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathwaysHong-Liang Li
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing, People's Republic of China
Free Radic Biol Med 40:1756-75. 2006..These findings indicated that EGCG prevents the development of cardiac hypertrophy through ROS-dependent and -independent mechanisms involving inhibition of different intracellular signaling transductional pathways... - Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesityLili A Barouch
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Circ Res 98:119-24. 2006..These data offer novel insights into potential mechanisms of myocardial dysfunction and early mortality in obesity... - New technology and clinical applications of nanomedicine: highlights of the second annual meeting of the American Academy of Nanomedicine (Part I)Chiming Wei
Johns Hopkins University, Baltimore, Maryland 21205, USA
Nanomedicine 2:253-63. 2006..We believe that nanomedicine research will develop rapidly in the future. The AANM invites basic and clinical researchers from the world to join this exciting research... - Nanomedicine and drug deliveryChiming Wei
Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
Med Clin North Am 91:863-70. 2007..The impedance biosensor is expected to find applications in monitoring cytokines in cancer, bone turnover markers in osteoporosis, and understanding neural-degenerative diseases... - Highlights of the first annual meeting of the American Academy of NanomedicineChiming Wei
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Nanomedicine 1:351-7. 2005 - Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver diseaseDaqing Gao
Department of Surgery, The Johns Hopkins University, Baltimore, Maryland 21205, USA
Am J Physiol Gastrointest Liver Physiol 287:G1070-7. 2004..These findings raise the intriguing possibility that inherited or acquired differences in DNA repair enzyme activity may underlie some of the interindividual differences in fatty liver disease outcomes... - From bench to bedside: successful translational nanomedicine: highlights of the Third Annual Meeting of the American Academy of NanomedicineChiming Wei
Molecular Nanomedicine Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Nanomedicine 3:322-31. 2007..The meeting provided exciting information for nanomedicine clinical-related researches and strategy for further development of nanomedicine research which will be benefits to clinical practice... - Increased mitochondrial reactive oxygen species production in newborn brain during hypoglycemiaJane E McGowan
Department of Pediatrics, School of Medicine, The Johns Hopkins University, USA
Neurosci Lett 399:111-4. 2006..Increased mitochondrial ROS production could result in alterations in brain structure and function due to oxidant injury to mitochondrial proteins and DNA or changes in oxidant-sensitive signal transduction pathways in brain... 
The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cordGlen Roseborough
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Pathol 168:1443-51. 2006....- New advances in nanomedicine: diagnosis and preventive medicineChiming Wei
Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
Med Clin North Am 91:871-9. 2007.... - Genetic nanomedicine and tissue engineeringChiming Wei
Department of Surgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street Harvey 606, Baltimore, MD 21205, USA
Med Clin North Am 91:889-98. 2007.... - Selective decrease in the DNA base excision repair pathway in squamous cell cancer of the esophagusPramod Bonde
Cardiothoracic Renal Research Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
J Thorac Cardiovasc Surg 133:74-81. 2007.... - Duodenal reflux leads to down regulation of DNA mismatch repair pathway in an animal model of esophageal cancerPramod Bonde
Cardiothoracic Renal Molecular Research Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Ann Thorac Surg 83:433-40; discussion 440. 2007..We tested the effect of reflux, either alone or in combination with the human dietary mutagen methyl-n-amyl nitrosamine (MNAN), on DNA damage in adenocarcinoma and squamous cell cancer of the esophagus in a rat model... - Impact of 24 h continuous hypothermic perfusion on heart preservation by assessment of oxidative stressTorin P Fitton
The Johns Hopkins Medical Institution, Baltimore, MD, USA
Clin Transplant 18:22-7. 2004..CHP offers several potential advantages: (1) resuscitation of non-beating heart donor organs, (2) time for HLA tissue typing, (3) facilitate interventions improving graft function, and (4) increased organ sharing... - Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alphaZheqing Cai
Vascular Program, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Cardiovasc Res 77:463-70. 2008..We investigated whether hypoxia-inducible factor 1 alpha (HIF-1 alpha) plays a role in the acute phase of ischaemic preconditioning (IPC)... - Attenuation of DNA damage in canine hearts preserved by continuous hypothermic perfusionTorin P Fitton
Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Ann Thorac Surg 80:1812-20. 2005..Continuous hypothermic perfusion reduces oxidative damage and extends preservation without compromising function... - Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathwaysHong Liang Li
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Beijing 100005, Peoples Republic of China
Free Radic Biol Med 38:243-57. 2005..These findings suggest that ISO prevents the development of cardiac hypertrophy through an antioxidant mechanism involving inhibition of different intracellular signaling transduction pathways... - New technology and clinical applications of nanomedicineLian Zuo
Department of Cardiology, Emory University School of Medicine, 101 Woodruff Circle, WMB319, Atlanta, GA 30322, USA
Med Clin North Am 91:845-62. 2007..Toxicologic considerations also are discussed... - Recent advances in basic and clinical nanomedicineK John Morrow
Newport Biotechnology Consultants, 625 Washington Avenue, Newport, KY 41071, USA
Med Clin North Am 91:805-43. 2007..Site-specific targeted drug delivery and personalized medicine are just a few concepts that are on the horizon... - beta(2)-Adrenergic stimulation attenuates left ventricular remodeling, decreases apoptosis, and improves calcium homeostasis in a rodent model of ischemic cardiomyopathySteve Xydas
Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
J Pharmacol Exp Ther 317:553-61. 2006..We conclude that clenbuterol ameliorates EDPVR, apoptosis, and calcium homeostasis but does not have synergy with metoprolol in our model of ischemic HF... - Nanomedicine in cancer treatmentTachung C Yih
Department of Medical Engineering and Biomechanics, University of Texas at San Antonio, San Antonio, Texas, USA
Nanomedicine 1:191-2. 2005 - Modeling and characterization of a nanoliter drug-delivery MEMS micropump with circular bossed membraneTachung C Yih
Department of Mechanical Engineering and Biomechanics, University of Texas at San Antonio, San Antonio, Texas 78249, USA
Nanomedicine 1:164-75. 2005..Integration of the function over 1 driving cycle and multiplication by the driving frequency provides the drug-delivery rate of the micropump... - Quantum dots for robust and simple assays using single particles in nanodevicesPeixuan Guo
Purdue University, West hafayette, Indiada John Hopkins University, USA
Nanomedicine 1:122-4. 2005
Research Grants
- GROWTH AND DEATH OF VASCULAR SMOOTH MUSCLE CELLSChiming Wei; Fiscal Year: 2002..Aim 4. To determine the relationship of the p53 gene with p21-WAF gene and bcl-2 gene expression during NPS-induced apoptosis in VSMC isolated from IMA and SV. ..