Maria J Wawer

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. pmc Risk factors for intimate partner violence in women in the Rakai Community Cohort Study, Uganda, from 2000 to 2009
    Fiona G Kouyoumdjian
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario Canada
    BMC Public Health 13:566. 2013
  2. ncbi request reprint Challenges in assessing associations between hormonal contraceptive use and the risks of HIV-1 acquisition and transmission
    Maria J Wawer
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Future Microbiol 7:315-8. 2012
  3. pmc Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial
    Maria J Wawer
    Department of Population, Family and Reproductive Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 374:229-37. 2009
  4. ncbi request reprint Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda
    Maria J Wawer
    Heilbrun Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    J Infect Dis 191:1403-9. 2005
  5. pmc High-risk human papillomavirus viral load and persistence among heterosexual HIV-negative and HIV-positive men
    Mary K Grabowski
    Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
    Sex Transm Infect 90:337-43. 2014
  6. pmc Human papillomavirus incidence and clearance among HIV-positive and HIV-negative men in sub-Saharan Africa
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287, USA
    AIDS 26:1555-65. 2012
  7. pmc Male circumcision for the prevention of HSV-2 and HPV infections and syphilis
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    N Engl J Med 360:1298-309. 2009
  8. pmc Determinants of incidence and clearance of high-risk human papillomavirus infections in rural Rakai, Uganda
    Mahboobeh Safaeian
    Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Cancer Epidemiol Biomarkers Prev 17:1300-7. 2008
  9. pmc Male circumcision decreases acquisition and increases clearance of high-risk human papillomavirus in HIV-negative men: a randomized trial in Rakai, Uganda
    Ronald H Gray
    Department of Population, Family, and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Infect Dis 201:1455-62. 2010
  10. ncbi request reprint Clinical illness as a marker for initiation of HIV antiretroviral therapy in a rural setting, Rakai, Uganda
    Lisa A Spacek
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Int J STD AIDS 17:116-20. 2006

Detail Information

Publications85

  1. pmc Risk factors for intimate partner violence in women in the Rakai Community Cohort Study, Uganda, from 2000 to 2009
    Fiona G Kouyoumdjian
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario Canada
    BMC Public Health 13:566. 2013
    ..There is a lack of data on IPV risk factors from longitudinal studies and from low and middle income countries. Identifying risk factors is needed to inform the design of appropriate IPV interventions...
  2. ncbi request reprint Challenges in assessing associations between hormonal contraceptive use and the risks of HIV-1 acquisition and transmission
    Maria J Wawer
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Future Microbiol 7:315-8. 2012
    ..Clinicians and clients need to balance potential HC risks with the known risks of unwanted pregnancies. Condom use remains essential for HIV prevention regardless of other contraceptive usage...
  3. pmc Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial
    Maria J Wawer
    Department of Population, Family and Reproductive Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 374:229-37. 2009
    ..We assessed whether circumcision in HIV-infected men would reduce transmission of the virus to female sexual partners...
  4. ncbi request reprint Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda
    Maria J Wawer
    Heilbrun Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    J Infect Dis 191:1403-9. 2005
    ..We estimated rates of human immunodeficiency virus (HIV)-1 transmission per coital act in HIV-discordant couples by stage of infection in the index partner...
  5. pmc High-risk human papillomavirus viral load and persistence among heterosexual HIV-negative and HIV-positive men
    Mary K Grabowski
    Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
    Sex Transm Infect 90:337-43. 2014
    ..High-risk human papillomavirus (HR-HPV) viral load is associated with HR-HPV transmission and HR-HPV persistence in women. It is unknown whether HR-HPV viral load is associated with persistence in HIV-negative or HIV-positive men...
  6. pmc Human papillomavirus incidence and clearance among HIV-positive and HIV-negative men in sub-Saharan Africa
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287, USA
    AIDS 26:1555-65. 2012
    ..Penile and cervical cancer rates are highest in sub-Saharan Africa. However, little is known about the impact of HIV infection on HR-HPV acquisition and clearance among heterosexual men...
  7. pmc Male circumcision for the prevention of HSV-2 and HPV infections and syphilis
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    N Engl J Med 360:1298-309. 2009
    ..We assessed the efficacy of male circumcision for the prevention of herpes simplex virus type 2 (HSV-2) and human papillomavirus (HPV) infections and syphilis in HIV-negative adolescent boys and men...
  8. pmc Determinants of incidence and clearance of high-risk human papillomavirus infections in rural Rakai, Uganda
    Mahboobeh Safaeian
    Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Cancer Epidemiol Biomarkers Prev 17:1300-7. 2008
    ..We used self-administered vaginal swabs to assess the incidence and clearance of carcinogenic human papillomavirus (HPV) infections in rural Rakai, Uganda...
  9. pmc Male circumcision decreases acquisition and increases clearance of high-risk human papillomavirus in HIV-negative men: a randomized trial in Rakai, Uganda
    Ronald H Gray
    Department of Population, Family, and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Infect Dis 201:1455-62. 2010
    ..HR-HPV clearance was determined in men with prior genotype-specific HR-HPV infections. Rate ratios (RRs) and 95% confidence intervals (CIs) of HR-HPV acquisition were estimated by Poisson multiple regression...
  10. ncbi request reprint Clinical illness as a marker for initiation of HIV antiretroviral therapy in a rural setting, Rakai, Uganda
    Lisa A Spacek
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Int J STD AIDS 17:116-20. 2006
    ..6%; P = 0.001).HIV-related illness and WHO stage predicted disease progression. The specificity of clinical illness to predict viral load >55,000 copies/mL was high and could be used to rule in HIV disease requiring ART...
  11. pmc Effects of genital ulcer disease and herpes simplex virus type 2 on the efficacy of male circumcision for HIV prevention: Analyses from the Rakai trials
    Ronald H Gray
    Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS Med 6:e1000187. 2009
    ..We assessed the role of GUD and HSV-2 in the protection against HIV afforded by MC...
  12. pmc High-risk human papillomavirus prevalence is associated with HIV infection among heterosexual men in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Sex Transm Infect 89:122-7. 2013
    ..Knowledge of HR-HPV prevalence, risk factors and genotype distribution among heterosexual men is important to establish risk-reduction prevention strategies...
  13. ncbi request reprint Increased risk of incident HIV during pregnancy in Rakai, Uganda: a prospective study
    Ronald H Gray
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, USA
    Lancet 366:1182-8. 2005
    ..HIV acquisition is significantly higher during pregnancy than in the postpartum period. We did a prospective study to estimate HIV incidence rates during pregnancy and lactation...
  14. pmc Circumcision of HIV-infected men and transmission of human papillomavirus to female partners: analyses of data from a randomised trial in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Lancet Infect Dis 11:604-12. 2011
    ..We assessed whether circumcision of HIV-infected men would reduce the transmission of high-risk HPV to their female partners...
  15. ncbi request reprint Determinants of HIV-1 load in subjects with early and later HIV infections, in a general-population cohort of Rakai, Uganda
    Ronald H Gray
    Department of Population and Family Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    J Infect Dis 189:1209-15. 2004
    ..GUD was consistently associated with higher HIV loads in subjects with incident and those with prevalent HIV infection, suggesting that treatment of GUD might reduce HIV viremia...
  16. pmc Effect of circumcision of HIV-negative men on transmission of human papillomavirus to HIV-negative women: a randomised trial in Rakai, Uganda
    Maria J Wawer
    Department of Population, Family, and Reproductive Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287, USA
    Lancet 377:209-18. 2011
    ..We assessed the efficacy of male circumcision to reduce prevalence and incidence of high-risk HPV in female partners of circumcised men...
  17. pmc Marriage and the risk of incident HIV infection in Rakai, Uganda
    Fred Nalugoda
    Rakai Health Sciences Program, Entebbe, Uganda Makerere University School of Public Health, Kampala, Uganda Uganda Virus Research Institute, Entebbe, Uganda Makerere University College of Health Sciences, Kampala, Uganda and Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    J Acquir Immune Defic Syndr 65:91-8. 2014
    ..Studies suggest that the prevalence of HIV is higher among long-term marital/consensual relationships than in the unmarried. We assessed the risk of incident HIV infection by marital status in rural Rakai, Uganda...
  18. pmc Male circumcision and Mycoplasma genitalium infection in female partners: a randomised trial in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Sex Transm Infect 90:150-4. 2014
    ..Previous randomised trial data have demonstrated that male circumcision reduces Mycoplasma genitalium prevalence in men. We assessed whether male circumcision also reduces M genitalium infection in female partners of circumcised men...
  19. pmc Human papillomavirus clearance among males is associated with HIV acquisition and increased dendritic cell density in the foreskin
    Aaron A R Tobian
    Department of Pathology, Johns Hopkins University, Carnegie 437, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Infect Dis 207:1713-22. 2013
    ..The association between human papillomavirus (HPV) infection and the risk of human immunodeficiency virus (HIV) seroconversion is unclear, and the genital cellular immunology has not been evaluated...
  20. pmc Effect of hormonal contraceptive use on HIV progression in female HIV seroconverters in Rakai, Uganda
    Chelsea B Polis
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    AIDS 24:1937-44. 2010
    ..To assess the association between hormonal contraceptive use and HIV progression...
  21. pmc Male circumcision and anatomic sites of penile high-risk human papillomavirus in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    Int J Cancer 129:2970-5. 2011
    ..3% vs. 23.8%, respectively, p = 0.02) and circumcised men (21.5% vs. 15.5%, respectively, p = 0.24). MC reduced HR-HPV prevalence on both the coronal sulcus and shaft...
  22. pmc Geographic HIV type 1 subtype distribution in Rakai district, Uganda
    Aleisha N Collinson-Streng
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 25:1045-8. 2009
    ..001) and more subtype D in southern clusters compared with northern clusters (78% vs. 65%, p < 0.008). These data illustrate the geographic complexity of subtype variation, which has important implications for HIV-1 vaccine design...
  23. ncbi request reprint Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial
    Ronald H Gray
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21215, USA
    Lancet 369:657-66. 2007
    ..Ecological and observational studies suggest that male circumcision reduces the risk of HIV acquisition in men. Our aim was to investigate the effect of male circumcision on HIV incidence in men...
  24. pmc Reactivation of herpes simplex virus type 2 after initiation of antiretroviral therapy
    Aaron A R Tobian
    Department of Pathology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21287, USA
    J Infect Dis 208:839-46. 2013
    ..The association between initiation of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection and possible herpes simplex virus type 2 (HSV-2) shedding and genital ulcer disease (GUD) has not been evaluated...
  25. pmc Male circumcision and herpes simplex virus type 2 infection in female partners: a randomized trial in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    J Infect Dis 205:486-90. 2012
    ..17 cases per 100 person-years in the control arm (IRR, 0.85 [95% CI, .44-1.67]; P = .62). Contrary to findings in males, male circumcision did not affect HSV-2 acquisition among female partners...
  26. ncbi request reprint Stochastic simulation of the impact of antiretroviral therapy and HIV vaccines on HIV transmission; Rakai, Uganda
    Ronald H Gray
    Department of Population and Family Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
    AIDS 17:1941-51. 2003
    ..To model the effects of antiretroviral therapy (ART) and HIV vaccines on HIV transmission using empirical data from studies in Rakai, Uganda...
  27. pmc The effects of male circumcision on female partners' genital tract symptoms and vaginal infections in a randomized trial in Rakai, Uganda
    Ronald H Gray
    Department of Population, Family, and Reproductive Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Obstet Gynecol 200:42.e1-7. 2009
    ..The objective of the study was to assess effects of male circumcision on female genital symptoms and vaginal infections...
  28. pmc Effect of hormonal contraceptive use before HIV seroconversion on viral load setpoint among women in Rakai, Uganda
    Chelsea B Polis
    Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21202, USA
    J Acquir Immune Defic Syndr 56:125-30. 2011
    ..High viral load (VL) setpoint is a marker for rapid HIV progression. Few studies have examined whether use of hormonal contraception (HC) prior to HIV seroconversion affects VL setpoint...
  29. doi request reprint Behavioral, biological, and demographic risk and protective factors for new HIV infections among youth in Rakai, Uganda
    John S Santelli
    Heilbrunn Department of Population and Family Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 63:393-400. 2013
    ..We examined incidence of HIV infection and risk and protective factors among youth in rural Uganda, including the role of gender and social transitions...
  30. pmc Male circumcision reduces penile high-risk human papillomavirus viral load in a randomised clinical trial in Rakai, Uganda
    Lauren E Wilson
    Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA
    Sex Transm Infect 89:262-6. 2013
    ..The goal of this study was to examine the effect of circumcision on HPV viral load among HPV-infected men in a randomised trial of male circumcision...
  31. doi request reprint The effectiveness of male circumcision for HIV prevention and effects on risk behaviors in a posttrial follow-up study
    Ron Gray
    John Hopkins University, Baltimore, Maryland, USA
    AIDS 26:609-15. 2012
    ..The efficacy of male circumcision for HIV prevention over 2 years has been demonstrated in three randomized trials, but the longer-term effectiveness of male circumcision is unknown...
  32. pmc Foreskin inflammation is associated with HIV and herpes simplex virus type-2 infections in Rakai, Uganda
    Kristine E Johnson
    Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, USA
    AIDS 23:1807-15. 2009
    ..We assessed foreskin inflammation associated with HIV and herpes simplex virus type 2 (HSV-2) in circumcised men...
  33. pmc Incident HIV and herpes simplex virus type 2 infection among men in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    AIDS 23:1589-94. 2009
    ..Herpes simplex virus type 2 (HSV-2) infection is associated with an increased risk for acquiring HIV, but little is known about the temporal sequence of these infections...
  34. pmc Changes in the distribution of HIV type 1 subtypes D and A in Rakai District, Uganda between 1994 and 2002
    Samantha A Conroy
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, Maryland, USA
    AIDS Res Hum Retroviruses 26:1087-91. 2010
    ..Over this 8-year period, the overall viral population in this region evolved toward the less virulent HIV-1A strain, most likely as a consequence of the faster disease progression and lower transmissibility of HIV-1D...
  35. doi request reprint Trends and correlates of hormonal contraceptive use among HIV-infected women in Rakai, Uganda, 1994-2006
    Chelsea B Polis
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Contraception 83:549-55. 2011
    ..Little is known about what factors correlate with hormonal contraceptive (HC) use in HIV-infected women in sub-Saharan Africa...
  36. pmc Limitations of rapid HIV-1 tests during screening for trials in Uganda: diagnostic test accuracy study
    Ronald H Gray
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BMJ 335:188. 2007
    ..To evaluate the limitations of rapid tests for HIV-1...
  37. pmc The rates of HIV superinfection and primary HIV incidence in a general population in Rakai, Uganda
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD 21205, USA
    J Infect Dis 206:267-74. 2012
    ..Human immunodeficiency virus (HIV) superinfection has been documented in high-risk individuals; however, the rate of superinfection among HIV-infected individuals within a general population remains unknown...
  38. pmc Decreased kidney function in a community-based cohort of HIV-Infected and HIV-negative individuals in Rakai, Uganda
    Gregory M Lucas
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 55:491-4. 2010
    ..However little is known about natural history HIV-related kidney disease or about background rates of reduced GFR in HIV-negative individuals in this region...
  39. ncbi request reprint The contribution of HIV-discordant relationships to new HIV infections in Rakai, Uganda
    Ron Gray
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
    AIDS 25:863-5. 2011
    ..3% and 17.6% in married persons with unknown partner status, and 29.3% and 42.7% in the unmarried. Voluntary counseling and testing targeting discordant couples is unlikely to have a substantial impact in this setting...
  40. doi request reprint Sexual coercion among adolescent women in Rakai, Uganda: does family structure matter?
    Nanlesta A Pilgrim
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Interpers Violence 28:1289-313. 2013
    ..Understanding the family dynamics underlying the risk and protective effects of a given household structure might highlight new ways in which to prevent sexual coercion...
  41. pmc Male circumcision decreases high-risk human papillomavirus viral load in female partners: a randomized trial in Rakai, Uganda
    Mitzie Ann Davis
    Department of Gynecology Oncology, Moores Cancer Center, UCSD, La Jolla, CA, USA
    Int J Cancer 133:1247-52. 2013
    ..83-1.24). Genotypes with high HR-HPV band intensity were more likely to persist (adjHR = 1.27 95% CI 1.07-1.50), irrespective of male partner circumcision status. MC reduces HR-HPV DNA load in newly infected female partners...
  42. pmc Effect of injectable contraceptive use on response to antiretroviral therapy among women in Rakai, Uganda
    Chelsea B Polis
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Contraception 86:725-30. 2012
    ..There is limited evidence on the effect of injectable contraception on response to antiretroviral therapy (ART)...
  43. ncbi request reprint The effects of placental malaria on mother-to-child HIV transmission in Rakai, Uganda
    Heena Brahmbhatt
    Department of Population and Family Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
    AIDS 17:2539-41. 2003
    ..After multivariate adjustment for HIV viral load, the risk of MTCT associated with placental malaria was 2.89 and with HIV viral load the risk was 2.85. Interventions to prevent malaria during pregnancy could potentially reduce MTCT...
  44. pmc Effects of HIV-1 and herpes simplex virus type 2 infection on lymphocyte and dendritic cell density in adult foreskins from Rakai, Uganda
    Kristine E Johnson
    Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Infect Dis 203:602-9. 2011
    ..To assess the cellular basis for these associations, we estimated immunologic cellular densities in foreskin tissue...
  45. pmc Identification of HIV superinfection in seroconcordant couples in Rakai, Uganda, by use of next-generation deep sequencing
    Andrew D Redd
    Johns Hopkins University School of Medicine, Rangos Building, Room 530, 855 N Wolfe St, Baltimore, MD 21205, USA
    J Clin Microbiol 49:2859-67. 2011
    ..Our results indicate that NGS can be used for detection of HIV superinfection within large cohorts, which could assist in determining the incidence and the epidemiologic, virologic, and immunological correlates of this phenomenon...
  46. pmc Combination implementation for HIV prevention: moving from clinical trial evidence to population-level effects
    Larry W Chang
    Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Lancet Infect Dis 13:65-76. 2013
    ..Only through careful consideration of how to implement and operationalise HIV prevention interventions will the HIV community be able to move from clinical trial evidence to population-level effects...
  47. pmc The natural history of bacterial vaginosis diagnosed by gram stain among women in Rakai, Uganda
    Marie E Thoma
    Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Sex Transm Dis 38:1040-5. 2011
    ..We report 2-year weekly vaginal flora changes based on Gram stain using lasagna plots...
  48. pmc Utility of a point-of-care malaria rapid diagnostic test for excluding malaria as the cause of fever among HIV-positive adults in rural Rakai, Uganda
    Lisa A Mills
    Johns Hopkins School of Medicine, Division of Infectious Diseases, Baltimore, Maryland, USA
    Am J Trop Med Hyg 82:145-7. 2010
    ..0-89.7) and 99.1% (95% CI: 96.8-99.9), respectively. The rapid diagnostic test accurately ruled malaria "in or out" at the point-of-care, facilitating appropriate clinical management and averting unnecessary anti-malarial therapy...
  49. doi request reprint Experiences of sexual coercion among adolescent women: qualitative findings from Rakai district, Uganda
    Jennifer Wagman
    Johns Hopkins University, USA
    J Interpers Violence 24:2073-95. 2009
    ..This information may help violence prevention programs develop a range of strategies for addressing sexual coercion among adolescents...
  50. pmc Longitudinal study of correlates of modern contraceptive use and impact of HIV care programmes among HIV concordant and serodiscordant couples in Rakai, Uganda
    Heena Brahmbhatt
    Assistant Professor, Department of Population, Reproductive and Family Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Fam Plann Reprod Health Care 40:208-16. 2014
    ..To assess trends and determinants of family planning use and impact of HIV serostatus among couples...
  51. doi request reprint A public health approach to intimate partner violence prevention in Uganda: the SHARE Project
    Jennifer A Wagman
    Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Violence Against Women 18:1390-412. 2012
    ..This article describes the design and implementation of SHARE, provides details on strategies and activities used, discusses challenges and lessons learned, and provides recommendations for other violence prevention programmers...
  52. ncbi request reprint Disclosure of HIV status on informed consent forms presents an ethical dilemma for protection of human subjects
    Ronald H Gray
    Department of Population and Family Health Sciences, The Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 41:246-8. 2006
    ....
  53. pmc Comparison of a high-resolution melting assay to next-generation sequencing for analysis of HIV diversity
    Matthew M Cousins
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Microbiol 50:3054-9. 2012
    ..The HRM diversity assay is faster and less expensive than NGS, facilitating rapid analysis of large studies of HIV diversity and evolution...
  54. ncbi request reprint HIV status and union dissolution in sub-Saharan Africa: the case of Rakai, Uganda
    Laura Porter
    Department of Population and Family Health Sciences, Johns Hopkins University, USA
    Demography 41:465-82. 2004
    ..These results highlight women's vulnerability to the social impact of HIV infection and the importance of dyadic studies of the disruption of unions...
  55. ncbi request reprint Comparability of self-collected vaginal swabs and physician-collected cervical swabs for detection of human papillomavirus infections in Rakai, Uganda
    Mahboobeh Safaeian
    Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 20852, USA
    Sex Transm Dis 34:429-36. 2007
    ..The objective of this study was to compare human papillomavirus (HPV) DNA testing between self-administered vaginal swabs and physician-administered cervical swabs in women from rural Rakai District, Uganda...
  56. ncbi request reprint Age differences in sexual partners and risk of HIV-1 infection in rural Uganda
    Robert J Kelly
    Department of Population and Family Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Acquir Immune Defic Syndr 32:446-51. 2003
    ..To assess whether differences in age between sexual partners affect the risk of HIV infection in female adolescents and young adults...
  57. doi request reprint Reassessing the hypothesis on STI control for HIV prevention
    Ronald H Gray
    Johns Hopkins University, Baltimore, MD 21205, USA
    Lancet 371:2064-5. 2008
  58. pmc The role of viral introductions in sustaining community-based HIV epidemics in rural Uganda: evidence from spatial clustering, phylogenetics, and egocentric transmission models
    Mary K Grabowski
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS Med 11:e1001610. 2014
    ....
  59. pmc Effect of daily aciclovir on HIV disease progression in individuals in Rakai, Uganda, co-infected with HIV-1 and herpes simplex virus type 2: a randomised, double-blind placebo-controlled trial
    Steven J Reynolds
    Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet Infect Dis 12:441-8. 2012
    ..We investigated the effect of daily suppressive aciclovir on HIV-1 disease progression in Rakai, Uganda...
  60. doi request reprint Programme science research on medical male circumcision scale-up in sub-Saharan Africa
    Ronald H Gray
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Sex Transm Infect 89:345-9. 2013
    ..Here, we describe challenges to implementation and discuss the ongoing and future role of implementation and programme science in addressing such challenges. ..
  61. ncbi request reprint Randomised trials of HIV prevention
    Ronald H Gray
    Department of Population and Family Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Lancet 370:200-1. 2007
  62. ncbi request reprint The effect of male circumcision on sexual satisfaction and function, results from a randomized trial of male circumcision for human immunodeficiency virus prevention, Rakai, Uganda
    Godfrey Kigozi
    Rakai Health Sciences Program, Entebbe, Uganda
    BJU Int 101:65-70. 2008
    ..To investigate the relationship between adult male circumcision and sexual satisfaction and function in men, as observational studies on the effect of adult male circumcision on sexual satisfaction show conflicting results...
  63. ncbi request reprint Maternal self-medication and provision of nevirapine to newborns by women in Rakai, Uganda
    Joseph Kagaayi
    Rakai Health Sciences Program, Uganda Virus Research Institute, Entebbe, Uganda
    J Acquir Immune Defic Syndr 39:121-4. 2005
    ..5%, 95% confidence interval [CI]: 0.3%-16.6%). Mothers can administer nevirapine to themselves and their newborns and can achieve low rates of perinatal HIV infection...
  64. ncbi request reprint The incidence of HIV-1 associated with injections and transfusions in a prospective cohort, Rakai, Uganda
    Noah Kiwanuka
    The Rakai Project, Uganda Virus Research Institute, Entebbe
    AIDS 18:342-4. 2004
    ..92 (CI 1.22-12.58) associated with transfusions. Sexual behaviours were significantly associated with HIV risk. Medical injections did not increase HIV acquisition in this rural Ugandan population...
  65. pmc The safety of adult male circumcision in HIV-infected and uninfected men in Rakai, Uganda
    Godfrey Kigozi
    Rakai Health Sciences Program, Entebbe, Uganda
    PLoS Med 5:e116. 2008
    ....
  66. ncbi request reprint Higher risk behaviour and rates of sexually transmitted diseases in Mwanza compared to Uganda may help explain HIV prevention trial outcomes
    Kate K Orroth
    London School of Hygiene and Tropical Medicine, London, UK
    AIDS 17:2653-60. 2003
    ....
  67. ncbi request reprint Human immunodeficiency virus acquisition associated with genital ulcer disease and herpes simplex virus type 2 infection: a nested case-control study in Rakai, Uganda
    David Serwadda
    Institute of Public Health, Makerere University, Kampala, Uganda
    J Infect Dis 188:1492-7. 2003
    ..HIV load is increased in HSV-2-positive subjects who seroconverted, suggesting a role for treatment of HSV-2 infection in HSV-2-seropositive, dually infected individuals...
  68. ncbi request reprint Hormonal contraceptive use and HIV-1 infection in a population-based cohort in Rakai, Uganda
    Mohammed Kiddugavu
    Rakai Project, Uganda Virus Research Institute, Entebbe, Uganda
    AIDS 17:233-40. 2003
    ..Hormonal contraceptives have been associated with increased risk of HIV acquisition...
  69. ncbi request reprint HIV dynamics and behaviour change as determinants of the impact of sexually transmitted disease treatment on HIV transmission in the context of the Rakai trial
    Eline L Korenromp
    Erasmus University Rotterdam, Department of Public Health, The Netherlands
    AIDS 16:2209-18. 2002
    ..To assess how the impact of sexually transmitted disease (STD) treatment on HIV incidence varies between stages of the HIV epidemic...
  70. pmc Performance of a commercial, type-specific enzyme-linked immunosorbent assay for detection of herpes simplex virus type 2-specific antibodies in Ugandans
    Oliver Laeyendecker
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Clin Microbiol 42:1794-6. 2004
    ..A higher index cutoff value was required for optimal sensitivity and specificity, and overall performance of the assay was not affected by HIV status...
  71. ncbi request reprint Voluntary HIV counseling and testing acceptance, sexual risk behavior and HIV incidence in Rakai, Uganda
    Joseph K B Matovu
    Rakai Health Sciences Program, Uganda Virus Research Institute, Entebbe, Uganda
    AIDS 19:503-11. 2005
    ..To assess the acceptance of voluntary HIV counseling and testing (VCT) and the effects of VCT on sexual risk behavior and HIV acquisition in Rakai, Uganda...
  72. ncbi request reprint Empirical observations underestimate the proportion of HIV infections attributable to sexually transmitted diseases in Mwanza and Rakai STD treatment trials: simulation results
    Ronald H Gray
    Sex Transm Dis 34:61; author reply 62. 2007
  73. ncbi request reprint The incidence and prevalence of orphanhood associated with parental HIV infection: a population-based study in Rakai, Uganda
    Fredrick E Makumbi
    Rakai Health Sciences Program, Uganda Virus Research Institute, Entebbe, Uganda
    AIDS 19:1669-76. 2005
    ..There are limited empirical data on the prevalence and incidence of orphanhood due to parental HIV infection...
  74. ncbi request reprint Personal and community benefits and harms of research: views from Rakai, Uganda
    Carrie Thiessen
    Department of Clinical Bioethics, National Institutes of Health, Bethesda, Maryland, USA
    AIDS 21:2493-501. 2007
    ..To assess what individuals in low-income countries perceive as benefits and harms of population-based HIV/STD research...
  75. ncbi request reprint Sexually transmitted infection management, safer sex promotion and voluntary HIV counselling and testing in the male circumcision trial, Rakai, Uganda
    Joseph Kb Matovu
    Rakai Health Sciences Programme, Uganda Virus Research Institute, Rakai, Uganda
    Reprod Health Matters 15:68-74. 2007
  76. ncbi request reprint Higher HIV-1 incidence and genetic complexity along main roads in Rakai District, Uganda
    Miguel A Arroyo
    US Military HIV Research Program USMHRP, Division of Retrovirology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    J Acquir Immune Defic Syndr 43:440-5. 2006
    ..To determine the association between the incidence of HIV-1 infection and the genetic complexity of HIV-1 strains in 2 geographic strata within Rakai District, Uganda...
  77. ncbi request reprint Repeat voluntary HIV counseling and testing (VCT), sexual risk behavior and HIV incidence in Rakai, Uganda
    Joseph K B Matovu
    Rakai Health Sciences Program Uganda Virus Research Institute, Entebbe, Uganda
    AIDS Behav 11:71-8. 2007
    ..6/100 py in first time acceptors and 1.6/100 py in non-acceptors. These data suggest a need for intensive risk-reduction counseling interventions targeting HIV-negative repeat VCT acceptors as a special risk group...
  78. ncbi request reprint Reduced fertility among HIV-infected women associated with viral load in Rakai district, Uganda
    Ruby H N Nguyen
    Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, NC 27709, USA
    Int J STD AIDS 17:842-6. 2006
    ..OR of live birth which was 12% of the previous viral load category. Our data suggest that there may be considerable differences in the ability to produce a live birth among HIV-positive women with high viral loads...
  79. ncbi request reprint WHO HIV clinical staging or CD4 cell counts for antiretroviral therapy eligibility assessment? An evaluation in rural Rakai district, Uganda
    Joseph Kagaayi
    Rakai Health Sciences Programme, Rakai, Uganda
    AIDS 21:1208-10. 2007
    ..Clinical criteria missed half the patients with CD4 cell counts of 200 cells/microl or less, highlighting the importance of CD4 cell measurements for the scale-up of ART provision in resource-limited settings...
  80. ncbi request reprint Treatment of Trichomonas in pregnancy and adverse outcomes of pregnancy: a subanalysis of a randomized trial in Rakai, Uganda
    Godfrey G Kigozi
    Rakai Project, Uganda Virus Research Institute, Entebbe and Kampala, Uganda
    Am J Obstet Gynecol 189:1398-400. 2003
    ..The purpose of this study was to assess the association of presumptive Trichomonas vaginalis treatment during pregnancy and birth outcomes...
  81. ncbi request reprint Research benefits for hypothetical HIV vaccine trials: The views of Ugandans in the Rakai District
    Christine Grady
    Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    IRB 30:1-7. 2008
  82. ncbi request reprint Knowledge about vaccines and willingness to participate in preventive HIV vaccine trials: a population-based study, Rakai, Uganda
    Noah Kiwanuka
    Rakai Project, Uganda Virus Research Institute, Entebbe
    J Acquir Immune Defic Syndr 36:721-5. 2004
    ..However, there still is need for education on the potential role of preventive HIV vaccines in the control of the epidemic and the importance of vaccination for men, especially in the context of an HIV vaccine...
  83. ncbi request reprint What proportion of episodes of gonorrhoea and chlamydia becomes symptomatic?
    Eline L Korenromp
    Department of Public Health, Erasmus University Rotterdam, The Netherlands
    Int J STD AIDS 13:91-101. 2002
    ..In populations with low treatment rates like Uganda, these probabilities can be very low. Here, health education should have priority in STD management programmes...
  84. ncbi request reprint Might male circumcision be more protective against HIV in the highly exposed? An immunological hypothesis
    Maria J Wawer
    AIDS 19:2181-2. 2005
  85. ncbi request reprint Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda
    Mohammed G Kiddugavu
    Rakai Health Science Program, Uganda Virus Research Institute, Entebbe, Uganda
    Sex Transm Dis 32:1-6. 2005
    ..The goal of this study was to assess azithromycin and/or benzathine penicillin for treatment of syphilis...