Research Topics
| J P WattSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Detail Information
Publications
Use of serology and urine antigen detection to estimate the proportion of adult community-acquired pneumonia attributable to Streptococcus pneumoniaeJ P Watt
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Epidemiol Infect 138:1796-803. 2010..Based on urine antigen and blood culture results, we estimated that 11% of clinical and 15% of radiographic CAP cases were due to pneumococcus in this population...
Risk factors for invasive pneumococcal disease among Navajo adultsJames P Watt
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Epidemiol 166:1080-7. 2007..The high prevalence of renal failure, alcoholism, and unemployment among Navajo adults compared with the general US population may explain some of their increased risk of IPD...
Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimatesJames P Watt
Hib Initiative, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Lancet 374:903-11. 2009..Hib disease can be almost completely eliminated through routine vaccination. We assessed the global burden of disease to help national policy makers and international donors set priorities...
Invasive pneumococcal disease among Navajo adults, 1989-1998James P Watt
Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 38:496-501. 2004..Navajo adults have rates of IPD that are 3-5-fold higher than those of the general US population. Additional research is needed to understand the reasons for this elevated risk and to develop prevention strategies...
Measuring the incidence of adult community-acquired pneumonia in a Native American communityJ P Watt
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, 621 N Wolfe Street, Baltimore, MD 21205, USA
Epidemiol Infect 138:1146-54. 2010..Both radiographic and clinical CAP were serious illnesses with more than half of patients hospitalized. Our case definitions and methods may be useful for comparing data across studies and conducting vaccine trials...
Nasopharyngeal versus oropharyngeal sampling for detection of pneumococcal carriage in adultsJames P Watt
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, 621 N Washington St, Baltimore, MD 21205, USA
J Clin Microbiol 42:4974-6. 2004..Sampling both sites may give more accurate results than sampling either site alone in studies of pneumococcal carriage in adults...
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimatesKatherine L O'Brien
GAVI s PneumoADIP, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Lancet 374:893-902. 2009..To support local and global policy decisions on pneumococcal disease prevention and treatment, we estimated country-specific incidence of serious cases and deaths in children younger than 5 years...
Global reduction of Hib disease: what are the next steps? Proceedings of the meeting Scottsdale, Arizona, September 22-25, 2002James P Watt
Department of International Health, the Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
J Pediatr 143:S163-87. 2003..In areas where Hib disease burden is not well characterized, additional work will be needed to understand the epidemiology of Hib disease and to communicate the value of Hib conjugate vaccine...
Delivering pneumococcal vaccine to a high risk population: the Navajo experienceAndrea L Benin
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Hum Vaccin 1:66-9. 2005....
Effect of community-wide conjugate pneumococcal vaccine use in infancy on nasopharyngeal carriage through 3 years of age: a cross-sectional study in a high-risk populationEugene V Millar
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Clin Infect Dis 43:8-15. 2006..2% vs. 29.8%; P = .01). CONCLUSION: Community-wide PnCRM7 vaccination in infancy reduces the prevalence of vaccine-type carriage and increases the prevalence of nonvaccine-type carriage through at least 3 years of age...
The prevalence and incidence of end-stage renal disease in Native American adults on the Navajo reservationM E Hochman
Department of International Health, Harvard Medical School, Boston, Massachusetts, USA
Kidney Int 71:931-7. 2007..0001) and among the Native American adults in the US (0.073%, P<0.0009), but lower than among the other Native American adults in the Southwest (0.17%, P<0.0003). The reasons behind these disparities merit further study...
Prevention of Haemophilus influenzae type b disease: past success and future challengesAruna Chandran
John Hopkins Bloomberg School of Public Health, Center for American Indian Health, Department of International Health, 621 N Washington St, Baltimore, MD 21205, USA
Expert Rev Vaccines 4:819-27. 2005..This review outlines the pathogenesis and epidemiology of Hib disease, and the various options for prevention...
Epidemiology of invasive Haemophilus influenzae type A disease among Navajo and White Mountain Apache children, 1988-2003Eugene V Millar
Center for American Indian Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Clin Infect Dis 40:823-30. 2005..As Hib disease rates decrease to very low levels, there are concerns that non-type b strains of H. influenzae may emerge as more prevalent causes of invasive disease in children...
Contributions of Native Americans to the global control of infectious diseasesMathuram Santosham
Center for American Indian Health, Department of International Health, Johns Hopkins University, 621 N Washington Street, Baltimore, MD 21205, USA
Vaccine 25:2366-74. 2007..The lessons learned from these studies and their resultant prevention or treatment interventions have been applied around the world, and have had a major impact in the reduction of global childhood morbidity and mortality...
Effectiveness of the 23-valent polysaccharide vaccine against invasive pneumococcal disease in Navajo adultsAndrea L Benin
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 188:81-9. 2003..PPV23 was not significantly effective among Navajo adults and may be inadequate to prevent serious pneumococcal disease in this population...
Indirect effect of 7-valent pneumococcal conjugate vaccine on pneumococcal colonization among unvaccinated household membersEugene V Millar
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Clin Infect Dis 47:989-96. 2008..Understanding the impact of PCV7 on carriage among vaccinated and unvaccinated community members is critical to interpreting, predicting, and understanding the impact of PCV7 on disease...
Azithromycin prophylaxis during a hospital outbreak of Mycoplasma pneumoniae pneumoniaT B Hyde
Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, and Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 183:907-12. 2001..Use of azithromycin prophylaxis in asymptomatic persons during an MP outbreak in a closed setting may be of value in reducing clinical illness...
Rapid assessment tool for Haemophilus influenzae type b disease in developing countriesDaniel R Feikin
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:1270-6. 2004..Results were affected by the quality of available data. The Hib rapid assessment tool can be useful to countries that desire a timely assessment of Hib disease rates...
Sensitivity of surveillance for Haemophilus influenzae Type b meningitisJennifer C Moïsi
Pediatr Infect Dis J 25:960. 2006
