Research Topics

Xiaobin Wang


Affiliation: Johns Hopkins University
Country: USA


  1. Huang X, Qin X, Yang W, Liu L, Jiang C, Zhang X, et al. MTHFR Gene and Serum Folate Interaction on Serum Homocysteine Lowering: Prospect for Precision Folic Acid Treatment. Arterioscler Thromb Vasc Biol. 2018;38:679-685 pubmed publisher
    ..Our data raised the prospect to tailor folic acid therapy according to individual MTHFR C677T genotype and folate status. URL: Unique identifier: NCT00794885. ..
  2. Wang G, Radovick S, Xu X, Xing H, Tang G, Bartell T, et al. Strategy for early identification of prediabetes in lean populations: New insight from a prospective Chinese twin cohort of children and young adults. Diabetes Res Clin Pract. 2018;146:101-110 pubmed publisher
    ..Our findings revealed that an upper end of normal fasting glucose was a simple and robust predictor of future higher risk of prediabetes/diabetes in this young and lean population. ..
  3. Raghavan R, Fallin M, Hong X, Wang G, Ji Y, Stuart E, et al. Cord and Early Childhood Plasma Adiponectin Levels and Autism Risk: A Prospective Birth Cohort Study. J Autism Dev Disord. 2018;: pubmed publisher
    ..Further research is warranted to confirm our findings and elucidate biological mechanisms. ..
  4. Wang H, Mueller N, Wang G, Hong X, Chen T, Ji Y, et al. The Joint Association of Small for Gestational Age and Nighttime Sleep with Blood Pressure in Childhood. Sci Rep. 2018;8:9632 pubmed publisher
    ..0056). In conclusion, in this prospective birth cohort, longer sleep duration in early childhood may mitigate the blood pressure-raising effect of being born small. ..
  5. Ji Y, Kong X, Wang G, Hong X, Xu X, Chen Z, et al. Distribution and determinants of plasma homocysteine levels in rural Chinese twins across the lifespan. Nutrients. 2014;6:5900-14 pubmed publisher
    ..The early identification of elevated Hcy will offer a window of opportunity for the primary prevention of CVD and metabolic syndrome. ..
  6. Ji Y, Hong X, Wang G, Chatterjee N, Riley A, Lee L, et al. A Prospective Birth Cohort Study on Early Childhood Lead Levels and Attention Deficit Hyperactivity Disorder: New Insight on Sex Differences. J Pediatr. 2018;199:124-131.e8 pubmed publisher
    ..These findings shed new light on the sex difference in ADHD and point to opportunities for early risk assessment and primary prevention of ADHD. ..
  7. Ji Y, Riley A, Lee L, Hong X, Wang G, Tsai H, et al. Maternal Biomarkers of Acetaminophen Use and Offspring Attention Deficit Hyperactivity Disorder. Brain Sci. 2018;8: pubmed publisher
    ..Maternal acetaminophen biomarkers were specifically associated with increased risk of ADHD diagnosis in offspring. Additional clinical and mechanistic investigations are warranted. ..
  8. Li M, Fallin M, Riley A, Landa R, Walker S, Silverstein M, et al. The Association of Maternal Obesity and Diabetes With Autism and Other Developmental Disabilities. Pediatrics. 2016;137:e20152206 pubmed publisher
    ..Maternal prepregnancy obesity and maternal diabetes in combination were associated with increased risk for ASD and ID. ASD with ID may be etiologically distinct from ASD without ID. ..
  9. Bustamante Helfrich B, Chilukuri N, He H, Cerda S, Hong X, Wang G, et al. Maternal vascular malperfusion of the placental bed associated with hypertensive disorders in the Boston Birth Cohort. Placenta. 2017;52:106-113 pubmed publisher
    ..Additional studies are needed to confirm and validate our findings, and evaluate the role of maternal vascular lesions of the placental bed in relation to postnatal growth and development of the offspring and effect modifiers. ..

More Information


  1. Ji Y, Riley A, Lee L, Volk H, Hong X, Wang G, et al. A Prospective Birth Cohort Study on Maternal Cholesterol Levels and Offspring Attention Deficit Hyperactivity Disorder: New Insight on Sex Differences. Brain Sci. 2017;8: pubmed publisher
    ..The findings based on this predominantly urban low-income minority birth cohort raise a new mechanistic perspective for understanding the origins of ADHD and the gender differences and future targets in the prevention of ADHD. ..