Affiliation: Johns Hopkins University
- Effective detection of rare variants in pooled DNA samples using Cross-pool tailcurve analysisTejasvi S Niranjan
McKusick Nathans Institute of Genetic Medicine and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Genome Biol 12:R93. 2011..Validation by Sanger sequencing revealed an excellent combination of sensitivity and specificity for variant detection in pooled samples of both cohorts as compared to publicly available algorithms...