Research Topics
Genomes and GenesSpecies | Jun WanSummaryAffiliation: Johns Hopkins University School of Medicine Location: Baltimore, USA Summary: Gene regulation Alternative splicing miRNA Gene network High-throughput data analysis Physics of periodic structures Publications
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Detail Information
Publications
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesisYu yi Lin
High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Cell 136:1073-84. 2009..Our findings demonstrate a regulatory function for the NuA4 complex in glucose metabolism and life span by acetylating a critical metabolic enzyme...
Relating periodicity of nucleosome organization and gene regulationJun Wan
Wilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Bioinformatics 25:1782-8. 2009..e. DNA sequence) and extrinsic forces (i.e. chromatin remodeling factors). We found that the extrinsic factors play a critical role in maintaining the periodic nucleosome organization...
Exact dynamic localization in curved AlGaAs optical waveguide arraysRajiv Iyer
Opt Express 15:3212-23. 2007..We also emonstrate the strong wavelength dependence of the beam relocalization for a four period structure...
Quasi-BLOCH oscillations in curved coupled optical waveguidesArash Joushaghani
Department of Electrical and Computer Engineering and Institute for Optical Science, University of Toronto, 10 King s College Road, Toronto, Ontario, M5S 3G4, Canada
Phys Rev Lett 103:143903. 2009..Through comparisons with other structures, we show that this dynamic localization is robust beyond the nearest-neighbor tight-binding approximation and exhibits a wavelength dependence different from conventional dynamic localization...
MicroRNA profile of the developing mouse retinaLaszlo Hackler
Departments of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Invest Ophthalmol Vis Sci 51:1823-31. 2010..Conclusions. Global expression profiling revealed dozens of miRNAs with significant expression changes in the developing retina. Precise patterns of expression of miRNAs suggest their specific roles in development...
Computational analysis of tissue-specific gene networks: application to murine retinal functional studiesJianfei Hu
Wilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Bioinformatics 26:2289-97. 2010....
