Eric C Vonderheid

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint On the diagnosis of erythrodermic cutaneous T-cell lymphoma
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD 21205, USA
    J Cutan Pathol 33:27-42. 2006
  2. ncbi request reprint Secondary syphilis presenting as pseudolymphoma of the skin
    Mary E McComb
    Department of Dermatology, Lehigh Valley Hospital, 7925 Ridge Avenue, Allentown, PA 19128, USA
    J Am Acad Dermatol 49:S174-6. 2003
  3. pmc Predictors of response to extracorporeal photopheresis in advanced mycosis fungoides and Sézary syndrome
    Laura Y McGirt
    Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    Photodermatol Photoimmunol Photomed 26:182-91. 2010
  4. doi request reprint Lymphomatoid papulosis followed by pityriasis lichenoides: a common pathogenesis?
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    Am J Dermatopathol 33:835-40. 2011
  5. ncbi request reprint The Sézary syndrome: hematologic criteria
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutions, 550 North Broadway, Suite 1002, Baltimore, MD 21205, USA
    Hematol Oncol Clin North Am 17:1367-89, viii. 2003
  6. ncbi request reprint Sézary cell counts in erythrodermic cutaneous T-cell lymphoma: implications for prognosis and staging
    Eric C Vonderheid
    Department of Dermatology and Oncology, Johns Hopkins Medical Institutes, 550 N Broadway, Baltimore, MD 21205, USA
    Leuk Lymphoma 47:1841-56. 2006
  7. ncbi request reprint Evidence for restricted Vbeta usage in the leukemic phase of cutaneous T cell lymphoma
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, Maryland 21205, USA
    J Invest Dermatol 124:651-61. 2005
  8. ncbi request reprint Treatment planning in cutaneous T-cell lymphoma
    Eric C Vonderheid
    Johns Hopkins Medical Institutes, Baltimore, Maryland 21205, USA
    Dermatol Ther 16:276-82. 2003
  9. doi request reprint Prognostic factors and risk stratification in early mycosis fungoides
    Eric C Vonderheid
    Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    Leuk Lymphoma 55:44-50. 2014
  10. doi request reprint Low FAS/CD95 expression by CTCL correlates with reduced sensitivity to apoptosis that can be restored by FAS upregulation
    Jianqiang Wu
    Department of Dermatology, University of Wisconsin and VAMC, Madison, Wisconsin 53715, USA
    J Invest Dermatol 129:1165-73. 2009

Collaborators

Detail Information

Publications33

  1. ncbi request reprint On the diagnosis of erythrodermic cutaneous T-cell lymphoma
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD 21205, USA
    J Cutan Pathol 33:27-42. 2006
    ....
  2. ncbi request reprint Secondary syphilis presenting as pseudolymphoma of the skin
    Mary E McComb
    Department of Dermatology, Lehigh Valley Hospital, 7925 Ridge Avenue, Allentown, PA 19128, USA
    J Am Acad Dermatol 49:S174-6. 2003
    ..The papulonodular variant has only been described 11 times in the literature. We describe a case of papulonodular secondary syphilis presenting as an atypical lymphoid hyperplasia suggestive of cutaneous lymphoma...
  3. pmc Predictors of response to extracorporeal photopheresis in advanced mycosis fungoides and Sézary syndrome
    Laura Y McGirt
    Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    Photodermatol Photoimmunol Photomed 26:182-91. 2010
    ....
  4. doi request reprint Lymphomatoid papulosis followed by pityriasis lichenoides: a common pathogenesis?
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    Am J Dermatopathol 33:835-40. 2011
    ..We report a patient who was diagnosed with LyP type B in 1985 followed by PL after 11 years. We hypothesize that LyP followed by PL in the same patient reflects differences in the host immune response to a common antigenic stimulus...
  5. ncbi request reprint The Sézary syndrome: hematologic criteria
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutions, 550 North Broadway, Suite 1002, Baltimore, MD 21205, USA
    Hematol Oncol Clin North Am 17:1367-89, viii. 2003
    ..Based on the experience at two institutions, revisions to the definition for Sézary syndrome are proposed...
  6. ncbi request reprint Sézary cell counts in erythrodermic cutaneous T-cell lymphoma: implications for prognosis and staging
    Eric C Vonderheid
    Department of Dermatology and Oncology, Johns Hopkins Medical Institutes, 550 N Broadway, Baltimore, MD 21205, USA
    Leuk Lymphoma 47:1841-56. 2006
    ..The clinical importance of these variables vis-à-vis the modified TNBM staging system will need to be clarified in future studies...
  7. ncbi request reprint Evidence for restricted Vbeta usage in the leukemic phase of cutaneous T cell lymphoma
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, Maryland 21205, USA
    J Invest Dermatol 124:651-61. 2005
    ..1 usage in CTCL may be the result of depletion of Vbeta2 and other Vbeta-bearing T cells by staphylococcal superantigens prior to neoplastic transformation, resulting in a relative increase in the frequency of Vbeta5.1 usage in CTCL...
  8. ncbi request reprint Treatment planning in cutaneous T-cell lymphoma
    Eric C Vonderheid
    Johns Hopkins Medical Institutes, Baltimore, Maryland 21205, USA
    Dermatol Ther 16:276-82. 2003
    ..The author's approach is provided as a guide for dermatologists in private practice...
  9. doi request reprint Prognostic factors and risk stratification in early mycosis fungoides
    Eric C Vonderheid
    Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    Leuk Lymphoma 55:44-50. 2014
    ..Combination of these factors was used to construct prognostic groupings which, if validated, might be useful to identify patients with clinically early MF at highest risk for disease progression and poor outcome. ..
  10. doi request reprint Low FAS/CD95 expression by CTCL correlates with reduced sensitivity to apoptosis that can be restored by FAS upregulation
    Jianqiang Wu
    Department of Dermatology, University of Wisconsin and VAMC, Madison, Wisconsin 53715, USA
    J Invest Dermatol 129:1165-73. 2009
    ....
  11. pmc High soluble CD30, CD25, and IL-6 may identify patients with worse survival in CD30+ cutaneous lymphomas and early mycosis fungoides
    Marshall E Kadin
    Department of Dermatology, Boston University, Roger Williams Medical Center, Providence, Rhode Island 02908, USA
    J Invest Dermatol 132:703-10. 2012
    ..We conclude that (1) neoplastic cells of some CD30CLPD patients do not resemble Th2 cells, and that (2) high serum sCD30, sCD25, IL-6, and perhaps IL-8 levels may provide prognostic information useful for patient management...
  12. doi request reprint Simplified flow cytometric assessment in mycosis fungoides and Sézary syndrome
    Alexandra C Hristov
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Clin Pathol 136:944-53. 2011
    ..Increasing numbers of abnormal T cells were associated with worsening disease. Flow cytometry provides valuable information for diagnosis, prognosis, and therapeutic efficacy in MF/SS...
  13. ncbi request reprint Chemokine receptor expression by leukemic T cells of cutaneous T-cell lymphoma: clinical and histopathological correlations
    Elisabetta Capriotti
    The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutes, Baltimore, Maryland, USA
    J Invest Dermatol 127:2882-92. 2007
    ..The chemokine receptor profile supports the concept that neoplastic T cells are central memory T cells, and that CCR10 and CD62L play a fundamental role respectively in epidermotropism and lymphadenopathy that is observed in SS...
  14. ncbi request reprint Multicolor fluorescence in situ hybridization (SKY) in mycosis fungoides and Sézary syndrome: search for recurrent chromosome abnormalities
    Denise A S Batista
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Genes Chromosomes Cancer 45:383-91. 2006
    ..2;p11.2). Two patients with SS reported in the literature seem to have a similar translocation. If confirmed, a psu dic(17;8) could be the first recurring translocation detected in at least three patients with MF/SS...
  15. ncbi request reprint Erythrodermic cutaneous T cell lymphoma with hypereosinophilic syndrome: Treatment with interferon alfa and extracorporeal photopheresis
    Catherine H Lee
    Department of Dermatology, Johns Hopkins University, Baltimore, MD 21205, USA
    Int J Dermatol 46:1198-204. 2007
    ..Eosinophilia is also recognized as a poor prognostic factor in cutaneous T-cell lymphoma (CTCL) in which neoplastic T cells may produce eosinophilopoietic cytokines...
  16. doi request reprint Cutaneous and systemic plasmacytosis vs. cutaneous plasmacytic castleman disease: review and speculations about pathogenesis
    Maryam Haque
    Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA 19107, USA
    Clin Lymphoma Myeloma Leuk 11:453-61. 2011
    ....
  17. doi request reprint Evaluation of the long-term tolerability and clinical benefit of vorinostat in patients with advanced cutaneous T-cell lymphoma
    Madeleine Duvic
    Department of Dermatology, The University of Texas M D Anderson Cancer Center, Box 1492, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Clin Lymphoma Myeloma 9:412-6. 2009
    ....
  18. ncbi request reprint Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris
    Simon S Yoo
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, Maryland 21287, USA
    J Dermatol 30:405-10. 2003
    ..This case provides an opportunity to discuss the difficulty of managing two potentially mortal conditions in which the treatment of pemphigus vulgaris may exacerbate the disseminated cryptococcal infection...
  19. ncbi request reprint Photopheresis: current and future perspectives
    Eric C Vonderheid
    Department of Dermatology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    J Cutan Med Surg 7:1-2. 2003
  20. ncbi request reprint CD158k/KIR3DL2 is a useful marker for identifying neoplastic T-cells in Sézary syndrome by flow cytometry
    David W Bahler
    Department of Pathology, University of Utah, Salt Lake City, Utah 84132, USA
    Cytometry B Clin Cytom 74:156-62. 2008
    ..Moreover, our observation that CD4 positive, CD7 negative T-cells are mostly CD158k negative further suggests that CD158k may be able to help identify and enumerate neoplastic T-cells in SS even when present at low levels...
  21. ncbi request reprint Papular mycosis fungoides: a variant of mycosis fungoides or lymphomatoid papulosis?
    Eric C Vonderheid
    J Am Acad Dermatol 55:177-80. 2006
  22. ncbi request reprint Infrequent Fas mutations but no Bax or p53 mutations in early mycosis fungoides: a possible mechanism for the accumulation of malignant T lymphocytes in the skin
    Olivier Dereure
    Department of Pathology, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, Massachusetts 02215, USA
    J Invest Dermatol 118:949-56. 2002
    ..These results support the hypothesis that Fas defects may play a role in the pathogenesis of MF...
  23. ncbi request reprint Heterogeneous abnormalities of CCND1 and RB1 in primary cutaneous T-Cell lymphomas suggesting impaired cell cycle control in disease pathogenesis
    Xin Mao
    Skin Tumour Unit, St John s Institute of Dermatology, St Thomas Hospital, King s College, London, UK
    J Invest Dermatol 126:1388-95. 2006
    ..These findings suggest heterogeneous abnormalities of CCND and RB in CTCL, in which dysregulated CCND and RB1 may lead to impaired cell cycle control...
  24. pmc Quantitative PCR on 5 genes reliably identifies CTCL patients with 5% to 99% circulating tumor cells with 90% accuracy
    Michael Nebozhyn
    The Wistar Institute, 3601 Spruce St, Philadelphia, PA 19104, USA
    Blood 107:3189-96. 2006
    ..These results are the first to demonstrate that gene expression profiling by quantitative PCR on a selected number of critical genes can be employed to molecularly diagnosis SS...
  25. ncbi request reprint Improved sensitivity of T-cell clonality detection in mycosis fungoides by hand microdissection and heteroduplex analysis
    Olivier Dereure
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Arch Dermatol 139:1571-5. 2003
    ..Procedures based on polymerase chain reaction (PCR) are the most sensitive to detect clonality, but heteroduplex analysis is less sensitive than other methods such as denaturing gradient gel electrophoresis...
  26. ncbi request reprint Treatment of cutaneous T cell lymphoma: 2001
    Eric C Vonderheid
    MCP Hahnemann University, Philadelphia, PA 19102, USA
    Recent Results Cancer Res 160:309-20. 2002
    ..Overall the future of therapy for CTCL seems quite optimistic...
  27. ncbi request reprint Diminished expression of the type II receptor for TGFbeta (TGFbetaRII) in T lymphocytes from patients with Sezary syndrome is not due to mutations in the receptor's poly-A tract: limitations of the standard RT-PCR in cDNA sequence analysis of homopolymeri
    Qian Zhang
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Arch Immunol Ther Exp (Warsz) 50:421-9. 2002
    ....
  28. pmc Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma
    Laszlo Kari
    Molecular Oncology Program, The Wistar Institute, 3601 Spruce St, Philadelphia, PA 19104, USA
    J Exp Med 197:1477-88. 2003
    ..Finally, we show that using 10 genes, we can identify a class of patients who will succumb within six months of sampling regardless of their tumor burden...
  29. ncbi request reprint Do neoplastic stem cells underlie the pathogenesis of cutaneous lymphomas?
    Eric C Vonderheid
    Arch Dermatol 141:641-2; author reply 642-3. 2005
  30. doi request reprint Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma
    Elisabetta Capriotti
    Department of Dermatology, University of Rome, Tor Vergata, Italy
    Leuk Lymphoma 49:1190-201. 2008
    ..Although the underlying mechanisms accounting for this correlation remain unclear, the expression of the Foxp3 and CTLA-4 regulatory elements indicates that a subset of leukemic cases displays a regulatory T-cell phenotype...
  31. doi request reprint Durable complete remission of mycosis fungoides following erythroderma induced by denileukin diftitox
    Rebecca Kazin
    J Am Acad Dermatol 58:S31-2. 2008
  32. ncbi request reprint Sézary syndrome coexisting with B-cell chronic lymphocytic leukemia: case report and review of the literature
    Syrus Karsai
    Laserklinik Karlsruhe, Karlsruhe, Germany
    Dermatology 216:68-75. 2008
    ..The simultaneous presentation of chronic B-cell lymphocytic leukemia (B-CLL) and cutaneous T-cell lymphoma (CTCL) is extremely rare...
  33. ncbi request reprint Update on erythrodermic cutaneous T-cell lymphoma: report of the International Society for Cutaneous Lymphomas
    Eric C Vonderheid
    MCP Hahnemann University, Philadelphia, Pennsylvannia 19102, USA
    J Am Acad Dermatol 46:95-106. 2002
    ..For staging purposes, it is proposed that these criteria define the B2 blood rating and that the B2 rating be considered equivalent to nodal involvement...