Research Topics
Species | K VisvanathanSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Publications
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breastBrian S Cornblatt
Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Carcinogenesis 28:1485-90. 2007..These findings provide a strong rationale for evaluating the protective effects of a broccoli sprout preparation in clinical trials of women at risk for breast cancer...
Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility studyKala Visvanathan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Surg Pathol 35:1766-75. 2011..The algorithm we propose is expected to help standardize the classification of STIC for future studies...
Bilateral oophorectomy, body mass index, and mortality in U.S. women aged 40 years and olderAnne Marie McCarthy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Cancer Prev Res (Phila) 5:847-54. 2012..Our results suggest that minimizing weight gain after oophorectomy and addressing cardiovascular risk factors could beneficially impact mortality...
Association among an ornithine decarboxylase polymorphism, androgen receptor gene (CAG) repeat length and prostate cancer riskKala Visvanathan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
J Urol 171:652-5. 2004..A nested case-control study was done to examine the association between this ODC genotype and prostate cancer risk, and whether it varies by AR gene CAG repeat length and smoking...
The reliability of nipple aspirate and ductal lavage in women at increased risk for breast cancer--a potential tool for breast cancer risk assessment and biomarker evaluationK Visvanathan
Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 16:950-5. 2007..However, little is known about the reliability of the procedure...
Alcohol dehydrogenase genetic polymorphisms, low-to-moderate alcohol consumption, and risk of breast cancerKala Visvanathan
Department of Epidemiology, The Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Alcohol Clin Exp Res 31:467-76. 2007..Because alcohol is a known risk factor for breast cancer, we evaluated the joint association of genetic variants in ADH and alcohol consumption in relation to breast cancer...
The importance of cytologic intrarater and interrater reproducibility: the case of ductal lavageKala Visvanathan
Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 15:2553-6. 2006..27 +/- 0.09. Fair to moderate intrarater and interrater agreement of DL cytology was observed. Low intrarater and interrater cytologic consistency may compromise the interpretation of clinical studies of DL...
Statin drugs and risk of advanced prostate cancerElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Rm E6138, 615 N Wolfe St, Baltimore, MD 21205, USA
J Natl Cancer Inst 98:1819-25. 2006..We investigated the association of statin use with total and advanced prostate cancer, the latter being the most important endpoint to prevent...
Estimated risk of radiation-induced breast cancer from mammographic screening for young BRCA mutation carriersAmy Berrington de Gonzalez
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
J Natl Cancer Inst 101:205-9. 2009..These results depend on a number of assumptions due to the absence of empiric data. The impact of varying these assumptions was therefore examined...
No association between pre-diagnostic plasma C-reactive protein concentration and subsequent prostate cancerElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Prostate 59:393-400. 2004..We evaluated the association of pre-diagnostic plasma concentration of C-reactive protein, a sensitive, but non-specific indicator of inflammation, with subsequent risk of prostate cancer...
Racial/ethnic and socioeconomic disparities in mortality among women diagnosed with cervical cancer in New York City, 1995-2006Anne Marie McCarthy
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cancer Causes Control 21:1645-55. 2010..This study assesses the relative impact of race/ethnicity and neighborhood poverty on cervical cancer incidence and mortality in New York City (NYC)...
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancerKonstantinos K Tsilidis
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
Cancer Causes Control 20:1739-51. 2009..Odds ratios (OR) and 95% confidence intervals (95% CI) were estimated using conditional logistic regression...
Cytochrome gene polymorphisms, serum estrogens, and hot flushes in midlife womenKala Visvanathan
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21201, USA
Obstet Gynecol 106:1372-81. 2005..The purpose of this study was to evaluate whether genetic polymorphisms in selected cytochrome P450 enzymes (CYPc17alpha, CYP1A1, and CYP1B1), estradiol (E2) levels, and estrone levels were associated with hot flushes...
Cigarette smoking, estrogen levels, and hot flashes in midlife womenLisa Gallicchio
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Maturitas 53:133-43. 2006..CONCLUSIONS: These findings indicate that smoking is associated with the occurrence of any and more severe hot flashes, independent of estrogen levels...
Body mass, estrogen levels, and hot flashes in midlife womenLisa Gallicchio
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Am J Obstet Gynecol 193:1353-60. 2005..Estrogen levels may partly explain this relationship; however, other mechanisms appear to be involved as well...
Ductal carcinoma in situ in African American versus Caucasian American women: analysis of clinicopathologic features and outcomeHind Nassar
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Cancer 115:3181-8. 2009..The characteristics of ductal carcinoma in situ (DCIS) in the AA population have not been extensively studied...
Elevated cancer mortality in the relatives of patients with pancreatic cancerLi Wang
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21231, USA
Cancer Epidemiol Biomarkers Prev 18:2829-34. 2009..Our results show that relatives of pancreatic cancer patients are at higher risk of developing cancers at other sites and highlight the importance of complete family history in clinical risk assessment...
Early detection and treatment of ovarian cancer: shifting from early stage to minimal volume of disease based on a new model of carcinogenesisRobert J Kurman
Department of Pathology, Bloomberg School of Public Health, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Am J Obstet Gynecol 198:351-6. 2008..A more rational approach to early detection of ovarian cancer should focus on low volume rather than low stage of disease...
Nonsteroidal anti-inflammatory drugs and the risk of developing breast cancer in a population-based prospective cohort study in Washington County, MDLisa Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, MD 21202, USA
Int J Cancer 121:211-15. 2007..Overall, findings from this study indicate that NSAID use is associated with a decrease in breast cancer risk and that the reduction in risk is similar for ER-positive and ER-negative tumors...
A phase I vaccine safety and chemotherapy dose-finding trial of an allogeneic GM-CSF-secreting breast cancer vaccine given in a specifically timed sequence with immunomodulatory doses of cyclophosphamide and doxorubicinLeisha A Emens
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21231-2410, USA
Hum Gene Ther 15:313-37. 2004
New findings about endocrine therapy for breast cancerNancy E Davidson
Johns Hopkins University, Schools of Medicine and Public Health, Baltimore, MD, USA
Breast 12:368-72. 2003..Ongoing research is focused on choice of endocrine approach, duration and sequencing of endocrine treatment, identification of better predictive markers for hormone response, and assessment of long-term risks and benefits...
Aromatase inhibitors as adjuvant therapy in breast cancerKala Visvanathan
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Oncology (Williston Park) 17:335-42, 347; discussion 347-50, 354. 2003..Ongoing trials are assessing the potential role of aromatase inhibitors in the adjuvant, neoadjuvant, and preventive settings...
Tumor COX-2 expression and prognosis of patients with resectable pancreatic cancerHiroyuki Matsubayashi
Department of Pathology, The Sol Goldman Pancreatic Research Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Cancer Biol Ther 6:1569-75. 2007..We evaluated the prognostic significance of COX-2 expression in pancreatic adenocarcinomas...
Epigenetic biomarkers and breast cancer: cause for optimismKala Visvanathan
Clin Cancer Res 12:6591-3. 2006
Research Grants
- K07 Preventive Oncology Academic AwardKala Visvanathan; Fiscal Year: 2007..abstract_text> ..
