Eileen P G Vining
Affiliation: Johns Hopkins University
- Long-term health consequences of epilepsy diet treatmentsEileen P G Vining
The John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 7247, USA
Epilepsia 49:27-9. 2008..Major areas of concern are reviewed as well as some emerging evidence of more beneficial long-term health consequences beyond the expected control of seizures...
- Growth of children on the ketogenic dietEileen P G Vining
The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Dev Med Child Neurol 44:796-802. 2002..The ketogenic diet generally provides sufficient nutrition to maintain growth within normal parameters over a defined period. Very young children grow poorly on the diet and should be followed-up carefully over long periods of use...
- The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one yearElisabeth B Marsh
John M Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MS 21287 1000, U S A
Epilepsia 47:425-30. 2006..To determine the long-term outcome of children with difficult-to-control seizures who remained on the ketogenic diet for <1 year...
- A blinded, crossover study of the efficacy of the ketogenic dietJohn M Freeman
Departments of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, Baltimore, Maryland, USA
Epilepsia 50:322-5. 2009..5 seizures per day (p = 0.07). There was no reduction in the number of EEG-identified events, with a median reduction of 7 events per day (p = 0.33). Ketosis was not completely eliminated in the glucose-added arm...
- Kidney stones and the ketogenic diet: risk factors and preventionAmitha Sampath
School of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Child Neurol 22:375-8. 2007..As oral potassium citrate was preventative, prospective studies using this medication empirically are warranted...
- A prospective study of the modified Atkins diet for intractable epilepsy in adultsEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Epilepsia 49:316-9. 2008..The modified Atkins diet has been recently demonstrated to be therapeutic for children without the need for an admission, fasting period, weighing of foods, or fluid, calorie, and protein restriction...
- Can you predict an immediate, complete, and sustained response to the ketogenic diet?Khoi D Than
The Johns Hopkins University School of Medicine, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Epilepsia 46:580-2. 2005..Although the ketogenic diet has been in use for >80 years, little agreement exists as to which patients are most likely to have dramatic, sudden, and complete seizure control...
- Clinical aspects of the ketogenic dietAdam L Hartman
The John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Epilepsia 48:31-42. 2007..Ketogenic diets now are being used for diseases other than epilepsy. This critical analysis of the diet should provide the impetus for further clinical and basic research into the diet's application and mechanisms of action...
- Experience in the use of the ketogenic diet as early therapyJames E Rubenstein
Department of Neurology, Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, MD 21287 1000, USA
J Child Neurol 20:31-4. 2005..6). The ketogenic diet can be a valuable therapy before epilepsy becomes intractable. In the 13 patients reported, efficacy without side effects was achieved similarly to that with patients with intractable epilepsy...
- Children with seizures exhibit preferences for foods compatible with the ketogenic dietAdrianna Amari
Department of Behavioral Psychology, The Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
Epilepsy Behav 11:98-104. 2007..Research into the underlying metabolic basis for this preference and possible related neurophysiological mechanisms in seizure etiology and treatment is warranted...
- Hemispherectomy sustained before adulthood does not cause persistent hemispatial neglectElisabeth B Marsh
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Cortex 45:677-85. 2009....
- High-dose oral prednisolone for infantile spasms: an effective and less expensive alternative to ACTHEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Epilepsy Behav 14:674-6. 2009..16. Oral prednisolone had fewer adverse effects (53% vs 80%, P=0.10) and was less expensive ($200 vs approximately $70,000) than ACTH. We now routinely recommend oral prednisolone to all families of children with infantile spasms...
- A randomized, crossover comparison of daily carbohydrate limits using the modified Atkins dietEric H Kossoff
The Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Epilepsy Behav 10:432-6. 2007..A starting carbohydrate limit of 10 g per day for children starting the modified Atkins diet may be ideal, with a planned increase to a more tolerable 20 g per day after 3 months...
- Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study GroupEric H Kossoff
The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Epilepsia 50:304-17. 2009..This paper highlights recommendations based on best evidence, including areas of agreement and controversy, unanswered questions, and future research...
- Effect of a high-fat ketogenic diet on plasma levels of lipids, lipoproteins, and apolipoproteins in childrenPeter O Kwiterovich
Lipid Research Atherosclerosis Division, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
JAMA 290:912-20. 2003..Little prospective long-term information is available on the effect of a ketogenic diet on plasma lipoproteins in children with difficult-to-control seizures...
- Efficacy of the ketogenic diet for infantile spasmsEric H Kossoff
Department of Neurology, Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Pediatrics 109:780-3. 2002..The objective of this study was to determine whether the ketogenic diet is safe, well-tolerated, and efficacious in the treatment of infantile spasms...
- Neonatal hypocalcemic seizures: case report and literature reviewEric H Kossoff
Pediatric Epilepsy, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Child Neurol 17:236-9. 2002..This case highlights the clinical course of neonatal hypocalcemic seizures, EEG findings in several cases, and possible mechanisms for both hypocalcemic precipitation of seizures and anticonvulsant ineffectiveness...
- The neuropharmacology of the ketogenic dietAdam L Hartman
John M Freeman Pediatric Epilepsy Center, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Pediatr Neurol 36:281-92. 2007....
- Walking flexibility after hemispherectomy: split-belt treadmill adaptation and feedback controlJulia T Choi
The Kennedy Krieger Institute, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Brain 132:722-33. 2009..These results suggest that the cerebrum is involved in adaptation of the timing, but not spatial, elements of limb movements...
- Kidney stones, carbonic anhydrase inhibitors, and the ketogenic dietEric H Kossoff
The Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, and Division of Pediatric Nephrology, Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1000, USA
Epilepsia 43:1168-71. 2002..The objective of this study was to establish the prevalence of nephrolithiasis in children in this combination-therapy population...
- Tonic and atonic seizures: medical therapy and ketogenic dietEileen P G Vining
Johns Hopkins Medical Institutions, Baltimore, Maryland 02118, USA
Epilepsia 50:21-4. 2009..Finally, although outcomes for these children are generally less than ideal, many can be helped with a persistent approach that balances seizure control against the side effects of medication...
- The pathology of Rasmussen syndrome: stages of cortical involvement and neuropathological studies in 45 hemispherectomiesCarlos A Pardo
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Epilepsia 45:516-26. 2004..To characterize the profile of cortical involvement in RS, we studied the pathological changes in the cerebral cortex of 45 hemispherectomies performed at Johns Hopkins Hospital between 1985 and 2002...
- The cognitive outcome of hemispherectomy in 71 childrenMargaret B Pulsifer
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114 2696, USA
Epilepsia 45:243-54. 2004..Seizures were due to cortical dysplasias (n = 27), Rasmussen syndrome (n = 37), or vascular malformations or strokes (n = 7). Both presurgical and follow-up results are available and reported for 53 patients...
- The ketogenic dietEileen P G Vining
Adv Exp Med Biol 497:225-31. 2002..One of the most significant trends in therapy has been the renewed popularity of the ketogenic diet. Dr. Vining discusses the history of the diet, its possible mechanisms of action and its clinical efficacy...