Russell Vang

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint p16 expression in primary ovarian mucinous and endometrioid tumors and metastatic adenocarcinomas in the ovary: utility for identification of metastatic HPV-related endocervical adenocarcinomas
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 31:653-63. 2007
  2. doi request reprint Fallopian tube precursors of ovarian low- and high-grade serous neoplasms
    Russell Vang
    Department of Pathology Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Histopathology 62:44-58. 2013
  3. pmc Validation of an algorithm for the diagnosis of serous tubal intraepithelial carcinoma
    Russell Vang
    Departments of Pathology, Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Int J Gynecol Pathol 31:243-53. 2012
  4. ncbi request reprint Immunohistochemistry for estrogen and progesterone receptors in the distinction of primary and metastatic mucinous tumors in the ovary: an analysis of 124 cases
    Russell Vang
    Department of Pathology, Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 19:97-105. 2006
  5. ncbi request reprint Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 19:1421-8. 2006
  6. ncbi request reprint Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 30:1130-9. 2006
  7. pmc Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems
    Russell Vang
    Department of Pathology Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Adv Anat Pathol 16:267-82. 2009
  8. ncbi request reprint Ovarian mucinous tumors associated with mature cystic teratomas: morphologic and immunohistochemical analysis identifies a subset of potential teratomatous origin that shares features of lower gastrointestinal tract mucinous tumors more commonly encounter
    Russell Vang
    Department of Pathology and Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 31:854-69. 2007
  9. doi request reprint Subdividing ovarian and peritoneal serous carcinoma into moderately differentiated and poorly differentiated does not have biologic validity based on molecular genetic and in vitro drug resistance data
    Russell Vang
    Department of Pathology, Division of Gynecologic Pathology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1667-74. 2008
  10. ncbi request reprint Pseudoinfiltrative tubal metaplasia of the endocervix: a potential form of in utero diethylstilbestrol exposure-related adenosis simulating minimal deviation adenocarcinoma
    Russell Vang
    Division of Gynecologic Pathology, Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland 21231, USA
    Int J Gynecol Pathol 24:391-8. 2005

Detail Information

Publications68

  1. ncbi request reprint p16 expression in primary ovarian mucinous and endometrioid tumors and metastatic adenocarcinomas in the ovary: utility for identification of metastatic HPV-related endocervical adenocarcinomas
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 31:653-63. 2007
    ....
  2. doi request reprint Fallopian tube precursors of ovarian low- and high-grade serous neoplasms
    Russell Vang
    Department of Pathology Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Histopathology 62:44-58. 2013
    ..This review paper provides an overview of the fallopian tube's potential role in the pathogenesis of both types of serous neoplasms of the ovary...
  3. pmc Validation of an algorithm for the diagnosis of serous tubal intraepithelial carcinoma
    Russell Vang
    Departments of Pathology, Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Int J Gynecol Pathol 31:243-53. 2012
    ..Accordingly, we recommend its use in research studies. Before applying it to routine clinical practice, the algorithm should be evaluated by general surgical pathologists in a community setting...
  4. ncbi request reprint Immunohistochemistry for estrogen and progesterone receptors in the distinction of primary and metastatic mucinous tumors in the ovary: an analysis of 124 cases
    Russell Vang
    Department of Pathology, Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 19:97-105. 2006
    ....
  5. ncbi request reprint Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 19:1421-8. 2006
    ..Cytokeratin 7 provides the predominant discriminatory value among these markers yet is limited to distinction of primary ovarian tumors from metastases of lower gastrointestinal tract origin...
  6. ncbi request reprint Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 30:1130-9. 2006
    ....
  7. pmc Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems
    Russell Vang
    Department of Pathology Division of Gynecologic Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Adv Anat Pathol 16:267-82. 2009
    ..This review provides an update on the pathogenesis and clinicopathologic features of these 2 types of serous carcinomas and addresses some of the diagnostic problems that are encountered in routine practice...
  8. ncbi request reprint Ovarian mucinous tumors associated with mature cystic teratomas: morphologic and immunohistochemical analysis identifies a subset of potential teratomatous origin that shares features of lower gastrointestinal tract mucinous tumors more commonly encounter
    Russell Vang
    Department of Pathology and Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 31:854-69. 2007
    ..Those tumors having CK7 expression with or without CK20 expression may be derived from upper gastrointestinal tract-type or sinonasal-type teratomatous elements but could be independent tumors of surface epithelial-stromal origin...
  9. doi request reprint Subdividing ovarian and peritoneal serous carcinoma into moderately differentiated and poorly differentiated does not have biologic validity based on molecular genetic and in vitro drug resistance data
    Russell Vang
    Department of Pathology, Division of Gynecologic Pathology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1667-74. 2008
    ..Accordingly, they can be simply classified as high-grade serous carcinoma...
  10. ncbi request reprint Pseudoinfiltrative tubal metaplasia of the endocervix: a potential form of in utero diethylstilbestrol exposure-related adenosis simulating minimal deviation adenocarcinoma
    Russell Vang
    Division of Gynecologic Pathology, Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland 21231, USA
    Int J Gynecol Pathol 24:391-8. 2005
    ..The clinicopathologic findings suggest the lesions are benign, and the association with in utero DES exposure raises the possibility that these could be a form of DES-related adenosis...
  11. doi request reprint Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis for both recently trained and experienced gynecologic pathologists
    Mamta Gupta
    Departments of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 36:1747-60. 2012
    ..93 to 0.96) but had no impact on distinction of PHMs and NMs. Genotyping provides a definitive diagnosis for the ∼25% to 50% of cases that are misclassified by morphology, especially those that are also unresolved by p57 immunostaining...
  12. doi request reprint TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma--evidence supporting the clonal relationship of the two lesions
    Elisabetta Kuhn
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Pathol 226:421-6. 2012
    ..Specifically, strong diffuse staining correlates with a missense mutation, whereas complete absence of staining correlates with null mutations...
  13. doi request reprint Endocervical adenocarcinomas with prominent endometrial or endomyometrial involvement simulating primary endometrial carcinomas: utility of HPV DNA detection and immunohistochemical expression of p16 and hormone receptors to confirm the cervical origin of
    Anna Yemelyanova
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:914-24. 2009
    ..A subset of misclassified endocervical adenocarcinomas may account for some HPV-positive uterine carcinomas reported as primary endometrial carcinomas...
  14. doi request reprint Endocervical adenocarcinomas with ovarian metastases: analysis of 29 cases with emphasis on minimally invasive cervical tumors and the ability of the metastases to simulate primary ovarian neoplasms
    Brigitte M Ronnett
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:1835-53. 2008
    ....
  15. doi request reprint Women with undiagnosed colorectal adenocarcinomas presenting with ovarian metastases: clinicopathologic features and comparison with women having known colorectal adenocarcinomas and ovarian involvement
    Kara Judson
    Department of Pathology, School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
    Int J Gynecol Pathol 27:182-90. 2008
    ....
  16. doi request reprint Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis
    Russell Vang
    Departments of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 36:443-53. 2012
    ..96 (almost perfect). Even with morphologic assessment by gynecologic pathologists and p57 immunohistochemistry, 20% to 30% of cases will be misclassified, and, in particular, distinction of PHMs and NMs will remain problematic...
  17. doi request reprint SF-1 is a diagnostically useful immunohistochemical marker and comparable to other sex cord-stromal tumor markers for the differential diagnosis of ovarian sertoli cell tumor
    Chengquan Zhao
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Int J Gynecol Pathol 27:507-14. 2008
    ....
  18. pmc Defining the cut point between low-grade and high-grade ovarian serous carcinomas: a clinicopathologic and molecular genetic analysis
    Ayse Ayhan
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:1220-4. 2009
    ....
  19. doi request reprint A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA Electronic address
    Hum Pathol 44:2494-500. 2013
    ..These and other mechanisms may contribute to the increased proliferation in malignant phyllodes relative to other fibroepithelial neoplasms. ..
  20. ncbi request reprint Expression of Rsf-1, a chromatin-remodeling gene, in ovarian and breast carcinoma
    Tsui Lien Mao
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Hum Pathol 37:1169-75. 2006
    ..Because Rsf-1 overexpression occurs in only a small number of breast carcinomas, it is unlikely that Rsf-1 is a critical gene in the development of breast carcinoma...
  21. doi request reprint The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression
    Andrea Proctor Subhawong
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA
    Mod Pathol 22:1423-31. 2009
    ..As cancers using the ALT pathway are predicted to be resistant to therapies based on telomerase inhibition, these results may have therapeutic consequences...
  22. doi request reprint GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 44:1341-9. 2013
    ..Finally, GATA3 labeling may help distinguish metaplastic carcinoma from malignant phyllodes tumors...
  23. doi request reprint Heterogeneity of Bcl-2 expression in metastatic breast carcinoma
    Andrea Proctor Subhawong
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Mod Pathol 23:1089-96. 2010
    ..Instead, downregulation of bcl-2 expression may occur in the setting of hormone therapy resistance. Our findings call into question the potential utility of anti-bcl-2 therapy in metastatic breast cancer...
  24. doi request reprint Are all pelvic (nonuterine) serous carcinomas of tubal origin?
    Christopher G Przybycin
    Departments of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Am J Surg Pathol 34:1407-16. 2010
    ....
  25. doi request reprint Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study
    Kala Visvanathan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Surg Pathol 35:1766-75. 2011
    ..The algorithm we propose is expected to help standardize the classification of STIC for future studies...
  26. ncbi request reprint Ovarian atypical proliferative (borderline) mucinous tumors: gastrointestinal and seromucinous (endocervical-like) types are immunophenotypically distinctive
    Russell Vang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Int J Gynecol Pathol 25:83-9. 2006
    ..quot;..
  27. pmc Endocervical-type mucinous borderline tumors are related to endometrioid tumors based on mutation and loss of expression of ARID1A
    Chen Hsuan Wu
    Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Int J Gynecol Pathol 31:297-303. 2012
    ..Accordingly, we suggest designating these tumors "atypical proliferative (borderline) papillary müllerian tumors" as this designation more accurately reflects their clinicopathologic, immunohistochemical, and molecular genetic features...
  28. ncbi request reprint Estrogen receptor alpha and progesterone receptor expression in ovarian adult granulosa cell tumors and Sertoli-Leydig cell tumors
    Maryam A Farinola
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Int J Gynecol Pathol 26:375-82. 2007
    ..These patterns of expression of ERalpha and PR may aid our understanding of the biologic differences between granulosa and Sertoli cell tumors...
  29. ncbi request reprint Ovarian metastases of appendiceal tumors with goblet cell carcinoidlike and signet ring cell patterns: a report of 30 cases
    Alexandra C Hristov
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, 401 N Broadway, Baltimore, MD 21231, USA
    Am J Surg Pathol 31:1502-11. 2007
    ..In cases in which the primary tumor is not already evident, their "goblet cell carcinoidlike" patterns should direct attention to the appendix as a possible source...
  30. ncbi request reprint Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification
    Anna V Yemelyanova
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 32:128-38. 2008
    ..Use of the algorithm is intended as an adjunct to the complete clinicopathologic evaluation that ideally should occur when problematic mucinous tumors in the ovary are encountered...
  31. pmc Papillary tubal hyperplasia: the putative precursor of ovarian atypical proliferative (borderline) serous tumors, noninvasive implants, and endosalpingiosis
    Robert J Kurman
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA
    Am J Surg Pathol 35:1605-14. 2011
    ..If this hypothesis is confirmed, it can be concluded that low-grade and high-grade ovarian tumors develop from tubal epithelium and involve the ovary secondarily...
  32. doi request reprint Uterine artery embolization with trisacryl gelatin microspheres in women treated for leiomyomas: a clinicopathologic analysis of alterations in gynecologic surgical specimens
    Zahra Maleki
    Department of Pathology, The Johns Hopkins Bayview Medical Center Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Int J Gynecol Pathol 29:260-8. 2010
    ..Finally, trisacryl gelatin microspheres can be distinguished from PVA particles and PVA microspheres based on a combination of morphologic features and histochemical stains...
  33. doi request reprint Relationship between molecular subtype of invasive breast carcinoma and expression of gross cystic disease fluid protein 15 and mammaglobin
    Gloria H Lewis
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Clin Pathol 135:587-91. 2011
    ..Correlation with clinical findings may be needed to exclude the possibility of a metastasis to the breast when BLCs or UTNCs are encountered in a limited sample such as a core biopsy sample...
  34. ncbi request reprint Nuclear size distinguishes low- from high-grade ovarian serous carcinoma and predicts outcome
    Chih Yi Hsu
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Hum Pathol 36:1049-54. 2005
    ..In addition, MNA is an independent prognostic factor for high-grade serous carcinoma...
  35. doi request reprint Characterization of androgenetic/biparental mosaic/chimeric conceptions, including those with a molar component: morphology, p57 immnohistochemistry, molecular genotyping, and risk of persistent gestational trophoblastic disease
    Gloria H Lewis
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Int J Gynecol Pathol 32:199-214. 2013
    ..The presence of androgenetic cell lines, particularly in those with a purely androgenetic CHM component, warrants follow-up because of some risk of persistent gestational trophoblastic disease...
  36. pmc Coexisting high-grade vulvar intraepithelial neoplasia (VIN) and condyloma acuminatum: independent lesions due to different HPV types occurring in immunocompromised patients
    Kruti P Maniar
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Am J Surg Pathol 37:53-60. 2013
    ..The presence of only HRHPV in those VIN lesions with high-grade cytologic features but prominent condylomatous architecture supports their classification as forms of pure high-grade VIN and distinguishes them from condyloma acuminatum...
  37. ncbi request reprint Diagnostic utility of WT1 immunostaining in ovarian sertoli cell tumor
    Chengquan Zhao
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 31:1378-86. 2007
    ..This marker is useful for the distinction of Sertoli cell tumor from endometrioid tumors and carcinoid. The diagnostic utility of WT1 in Sertoli cell tumor is similar to inhibin but better than that of calretinin...
  38. ncbi request reprint Utero-ovarian anastomosis: histopathologic correlation after uterine artery embolization with or without ovarian artery embolization
    Hyun S Kim
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Vasc Interv Radiol 18:31-9. 2007
    ..To study utero-ovarian anastomosis at angiography and its histologic effect on patients who were treated with uterine artery embolization (UAE) with or without ovarian artery embolization (OAE) for symptomatic uterine leiomyomata...
  39. doi request reprint Mutational analysis of BRAF and KRAS in ovarian serous borderline (atypical proliferative) tumours and associated peritoneal implants
    Laura Ardighieri
    Departments of Pathology and Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Pathol 232:16-22. 2014
    ....
  40. pmc MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumors
    Aatur D Singhi
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 25:378-87. 2012
    ..These observations underscore the importance of MYC in breast cancer progression/metastasis, as well as its relevance as a potential therapeutic target in otherwise incurable metastatic disease...
  41. doi request reprint Ovarian metastases of pancreaticobiliary tract adenocarcinomas: analysis of 35 cases, with emphasis on the ability of metastases to simulate primary ovarian mucinous tumors
    Zina Meriden
    Departments of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 35:276-88. 2011
    ..Loss of Dpc4 expression provides the most useful immunohistochemical evidence for establishing the pancreaticobiliary tract as the most likely source of these metastatic mucinous carcinomas in the ovary...
  42. pmc Molecular genotyping of hydatidiform moles: analytic validation of a multiplex short tandem repeat assay
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins Medical Institutions, Park Bldg Room SB202, 600 North Wolfe St, Baltimore, MD 21287, USA
    J Mol Diagn 11:598-605. 2009
    ..To avoid these pitfalls, we have developed an algorithm with quantitative guidelines for the interpretation of short tandem repeat genotyping data...
  43. ncbi request reprint The role of cytoreductive surgery for colon cancer metastatic to the ovary
    Colleen C McCormick
    Department of Gynecology and Obstetrics, Kelly Gynecologic Oncology Service, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Gynecol Oncol 105:791-5. 2007
    ..We sought to further elucidate the survival impact of cytoreductive surgery among patients with colon cancer metastatic to the ovary...
  44. doi request reprint Diagnosis and subclassification of hydatidiform moles using p57 immunohistochemistry and molecular genotyping: validation and prospective analysis in routine and consultation practice settings with development of an algorithmic approach
    Thomas G McConnell
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:805-17. 2009
    ....
  45. doi request reprint Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors
    Chengquan Zhao
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 33:354-66. 2009
    ....
  46. doi request reprint Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: an immunohistochemical and nucleotide sequencing analysis
    Anna Yemelyanova
    Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD 21231, USA
    Mod Pathol 24:1248-53. 2011
    ..Accordingly, this latter pattern, unlike low-level expression (10-50% cells), should not be construed as indicative of wild-type TP53...
  47. doi request reprint Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping
    Natalie Banet
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 27:238-54. 2014
    ..Cases with aberrant and discordant p57 expression can be correctly classified by genotyping. ..
  48. doi request reprint Clinically occult tubal and ovarian high-grade serous carcinomas presenting in uterine samples: diagnostic pitfalls and clues to improve recognition of tumor origin
    Christina Bagby
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Int J Gynecol Pathol 32:433-43. 2013
    ....
  49. doi request reprint Borderline atypical ductal hyperplasia/low-grade ductal carcinoma in situ on breast needle core biopsy should be managed conservatively
    Christopher J Vandenbussche
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 37:913-23. 2013
    ..In conclusion, our study provides preliminary data that justify a conservative approach to borderline ADH/DCIS lesions on CNB: that is, diagnose as MADH and treat by conservative excision...
  50. pmc Most basal-like breast carcinomas demonstrate the same Rb-/p16+ immunophenotype as the HPV-related poorly differentiated squamous cell carcinomas which they resemble morphologically
    Andrea Proctor Subhawong
    Department of Pathology, The Johns Hopkins Medical Institutions, MD 21231 2410, USA
    Am J Surg Pathol 33:163-75. 2009
    ..This subset may represent a more homogenous group than BLC as defined currently...
  51. pmc Precursor lesions of high-grade serous ovarian carcinoma: morphological and molecular characteristics
    Amy L Gross
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Oncol 2010:126295. 2010
    ....
  52. pmc Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma
    Ie Ming Shih
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Proc Natl Acad Sci U S A 102:14004-9. 2005
    ..Furthermore, Rsf-1 gene knockdown inhibited cell growth in OVCAR3 cells, which harbor Rsf-1 amplification. Taken together, these findings indicate an important role of Rsf-1 amplification in ovarian cancer...
  53. doi request reprint The diagnosis of endometrial carcinomas with clear cells by gynecologic pathologists: an assessment of interobserver variability and associated morphologic features
    Oluwole Fadare
    Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Surg Pathol 36:1107-18. 2012
    ..Cases that display broad and significant qualitative deviations from the aforementioned profile should prompt the consideration of a diagnosis other than CCC...
  54. ncbi request reprint Borderline ovarian tumors: diverse contemporary viewpoints on terminology and diagnostic criteria with illustrative images
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington DC 20010, USA
    Hum Pathol 35:918-33. 2004
    ..For those issues where there is disagreement, the terminology and diagnostic approaches reflecting the differing views are presented...
  55. ncbi request reprint Perivascular epithelioid cell tumor ('PEComa') of the uterus: a subset of HMB-45-positive epithelioid mesenchymal neoplasms with an uncertain relationship to pure smooth muscle tumors
    Russell Vang
    Department of Pathology, Laboratory of Surgical Pathology, Stanford University Medical Center, Stanford, California 94305, USA
    Am J Surg Pathol 26:1-13. 2002
    ....
  56. ncbi request reprint Effects of utero-ovarian anastomoses on basal follicle-stimulating hormone level change after uterine artery embolization with tris-acryl gelatin microspheres
    Hyun S Kim
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Blalock 545, Baltimore, Maryland 21205 4010, USA
    J Vasc Interv Radiol 17:965-71. 2006
    ..To assess the prevalence of anastomoses between uterine and ovarian arteries on angiography and their impact on changes in basal follicle-stimulating hormone (FSH) level after uterine artery embolization (UAE)...
  57. ncbi request reprint Elevated expression of p21 (WAF1/Cip1) in hormonally active pituitary adenomas
    Antonio G Neto
    Department of Pathology, Yale University, New Haven, CT, USA
    Ann Diagn Pathol 9:6-10. 2005
    ..Hormone-producing pituitary adenomas express much more p21 than do immunonegative adenomas. These high levels of p21 expression represent the most widespread molecular genetic alteration demonstrated to date in pituitary adenomas...
  58. ncbi request reprint Signet-ring stromal tumor of the ovary: clinicopathologic analysis and comparison with Krukenberg tumor
    Russell Vang
    Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Int J Gynecol Pathol 23:45-51. 2004
    ..Although the combination of operative and histopathologic findings allow their distinction, histochemical and immunohistochemical stains may also be useful...
  59. ncbi request reprint Immunohistochemical staining for Ki-67 and p53 helps distinguish endometrial Arias-Stella reaction from high-grade carcinoma, including clear cell carcinoma
    Russell Vang
    Armed Forces Institute of Pathology, Department of Gynecologic and Breast Pathology, Washington, DC, USA
    Int J Gynecol Pathol 23:223-33. 2004
    ....
  60. ncbi request reprint Comparative analysis of alternative and traditional immunohistochemical markers for the distinction of ovarian sertoli cell tumor from endometrioid tumors and carcinoid tumor: A study of 160 cases
    Chengquan Zhao
    Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology, Washington, DC, USA
    Am J Surg Pathol 31:255-66. 2007
    ..Chromogranin and synaptophysin are excellent discriminatory markers for carcinoid tumor, and CD56 is neither sufficiently sensitive nor specific enough for this differential diagnosis to warrant its use in routine practice...
  61. ncbi request reprint Comparative immunohistochemical analysis of granulosa and sertoli components in ovarian sex cord-stromal tumors with mixed differentiation: potential implications for derivation of sertoli differentiation in ovarian tumors
    Russell Vang
    Armed Forces Institute of Pathology, Department of Gynecologic and Breast Pathology, Washington DC, USA
    Int J Gynecol Pathol 23:151-61. 2004
    ..CD10 and low molecular weight cytokeratin are more often associated with Sertoli cell differentiation, whereas AR and vimentin expression seem to reflect granulosa differentiation...
  62. ncbi request reprint Immunohistochemical analysis of sox9 in ovarian Sertoli cell tumors and other tumors in the differential diagnosis
    Chengquan Zhao
    Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology, Washington, DC, USA
    Int J Gynecol Pathol 26:1-9. 2007
    ..Understanding the role of Sox9 in the pathogenesis of ovarian Sertoli cell tumor requires further study...
  63. ncbi request reprint Solitary fibrous tumor of the tongue: report of a case with immunohistochemical and ultrastructural studies
    Sang Ling Wu
    Department of Pathology and Laboratory Medicine, University of Texas Houston Medical School, Houston, TX 77030, USA
    Ann Diagn Pathol 6:168-71. 2002
    ..Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed...
  64. pmc A subset of morphologically distinct mammary myoepithelial cells lacks corresponding immunophenotypic markers
    Roy R Zhang
    Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology, Washington, DC, USA
    Breast Cancer Res 5:R151-6. 2003
    ..However, some morphologically distinct ME cells fail to stain for SMA. This study intended to assess whether these SMA-negative cells also lack the expression of other ME cell markers...
  65. pmc Cell clusters overlying focally disrupted mammary myoepithelial cell layers and adjacent cells within the same duct display different immunohistochemical and genetic features: implications for tumor progression and invasion
    Yan Gao Man
    Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology and American Registry of Pathology, Washington, DC, USA
    Breast Cancer Res 5:R231-41. 2003
    ..This is in contrast to the adjacent cells within the same duct, which were strongly immunoreactive for the ER. The current study attempts to confirm and expand previous observations on a larger scale...
  66. ncbi request reprint Current problems with staging lymphomas involving the ovary
    Russell Vang
    Am J Surg Pathol 30:1202-3. 2006
  67. ncbi request reprint Proliferative mucinous lesions of the endometrium: analysis of existing criteria for diagnosing carcinoma in biopsies and curettings
    Russell Vang
    Armed Forces Institute of Pathology Department of Gynecologic and Breast Pathology, Washington DC 20306 6000, USA
    Int J Surg Pathol 11:261-70. 2003
    ..However, the criteria of Nucci et al. do have utility. Application of the criteria available for endometrioid proliferations in biopsies/curettings that show mucinous lesions may be misleading...
  68. ncbi request reprint IHC comparison of antibodies 1D5 and 6F11 for estrogen receptor
    Russell Vang
    Appl Immunohistochem Mol Morphol 13:295. 2005