John C Umhau

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Low vitamin D status and suicide: a case-control study of active duty military service members
    John C Umhau
    National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    PLoS ONE 8:e51543. 2013
  2. pmc The physician's unique role in preventing violence: a neglected opportunity?
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, 10 Center Drive, Building 10 CRC Hatfield Center, Room 1 5330, Bethesda, MD 20892 1108, USA
    BMC Med 10:146. 2012
  3. pmc Dietary supplements and their future in health care: commentary on draft guidelines proposed by the Food and Drug Administration
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA
    Antioxid Redox Signal 16:461-2. 2012
  4. pmc Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography
    John C Umhau
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    J Lipid Res 50:1259-68. 2009
  5. pmc Fluoxetine treatment of alcoholic perpetrators of domestic violence: a 12-week, double-blind, randomized, placebo-controlled intervention study
    David T George
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bldg 10, Clinical Research Center, 10 Center Drive, Bethesda, MD 20892 1540, USA
    J Clin Psychiatry 72:60-5. 2011
  6. pmc Brain docosahexaenoic acid [DHA] incorporation and blood flow are increased in chronic alcoholics: a positron emission tomography study corrected for cerebral atrophy
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e75333. 2013
  7. pmc Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892 1108, USA
    Neuropsychopharmacology 36:1178-86. 2011
  8. ncbi request reprint A model linking biology, behavior and psychiatric diagnoses in perpetrators of domestic violence
    David T George
    Laboratory of Clinical and Translational Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive MSC 1540, Bldg 10 Hatfield CRC Room 2 2352, Bethesda, MD 20892 1540, USA
    Med Hypotheses 67:345-53. 2006
  9. pmc Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 1108, USA
    Arch Gen Psychiatry 67:1069-77. 2010
  10. ncbi request reprint Omega-3 status and cerebrospinal fluid corticotrophin releasing hormone in perpetrators of domestic violence
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852, USA
    Biol Psychiatry 56:895-7. 2004

Collaborators

Detail Information

Publications13

  1. pmc Low vitamin D status and suicide: a case-control study of active duty military service members
    John C Umhau
    National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    PLoS ONE 8:e51543. 2013
    ....
  2. pmc The physician's unique role in preventing violence: a neglected opportunity?
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, 10 Center Drive, Building 10 CRC Hatfield Center, Room 1 5330, Bethesda, MD 20892 1108, USA
    BMC Med 10:146. 2012
    ....
  3. pmc Dietary supplements and their future in health care: commentary on draft guidelines proposed by the Food and Drug Administration
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA
    Antioxid Redox Signal 16:461-2. 2012
    ..If inexpensive dietary supplements are found to be safe and effective, such research could yield significant cost savings as well as health benefits...
  4. pmc Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography
    John C Umhau
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    J Lipid Res 50:1259-68. 2009
    ..5 years. Thus, PET with [1-(11)C]DHA can be used to quantify regional and global human brain DHA metabolism in relation to health and disease...
  5. pmc Fluoxetine treatment of alcoholic perpetrators of domestic violence: a 12-week, double-blind, randomized, placebo-controlled intervention study
    David T George
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bldg 10, Clinical Research Center, 10 Center Drive, Bethesda, MD 20892 1540, USA
    J Clin Psychiatry 72:60-5. 2011
    ..This score served as a surrogate marker for the anger and physical aggression that characterize perpetrators of IPV...
  6. pmc Brain docosahexaenoic acid [DHA] incorporation and blood flow are increased in chronic alcoholics: a positron emission tomography study corrected for cerebral atrophy
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e75333. 2013
    ..In animal models, excessive alcohol consumption is reported to reduce brain DHA concentration, suggesting disturbed brain DHA metabolism. We hypothesized that brain DHA metabolism also is abnormal in chronic alcoholics...
  7. pmc Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892 1108, USA
    Neuropsychopharmacology 36:1178-86. 2011
    ..Under the experimental conditions used, alcohol cravings induced by these two stimuli are not sensitive to acamprosate at clinically used doses...
  8. ncbi request reprint A model linking biology, behavior and psychiatric diagnoses in perpetrators of domestic violence
    David T George
    Laboratory of Clinical and Translational Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive MSC 1540, Bldg 10 Hatfield CRC Room 2 2352, Bethesda, MD 20892 1540, USA
    Med Hypotheses 67:345-53. 2006
    ..Linking conditioned fear and fear avoidance to the behaviors and psychiatric diagnoses will serve to change the way the medical community perceives and treats perpetrators of domestic violence...
  9. pmc Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study
    John C Umhau
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 1108, USA
    Arch Gen Psychiatry 67:1069-77. 2010
    ..Human translation of these findings is lacking...
  10. ncbi request reprint Omega-3 status and cerebrospinal fluid corticotrophin releasing hormone in perpetrators of domestic violence
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852, USA
    Biol Psychiatry 56:895-7. 2004
    ..Prostaglandins E2 and F2alpha, which increase corticotrophin-releasing hormone RNA expression in this pathway, are reduced by dietary intakes of omega-3 fats...
  11. ncbi request reprint Cerebrospinal fluid monocyte chemoattractant protein-1 in alcoholics: support for a neuroinflammatory model of chronic alcoholism
    John C Umhau
    National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland
    Alcohol Clin Exp Res 38:1301-6. 2014
    ..Monocyte chemoattractant protein-1/chemokine (C-C motif) ligand 2 (MCP-1/CCL2) elevations have been noted in the alcoholic brain at autopsy and may have a role in this process...
  12. ncbi request reprint A select group of perpetrators of domestic violence: evidence of decreased metabolism in the right hypothalamus and reduced relationships between cortical/subcortical brain structures in position emission tomography
    David T George
    Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, 10 Center Drive, MSC 1610, Building 10, Room 6S 240, Bethesda, MD 20892 1610, USA
    Psychiatry Res 130:11-25. 2004
    ..A possible psychological covariate of these changes in regional activity might be fear-induced aggression, but this hypothesis should be examined in larger study groups that undergo provocation during imaging...
  13. pmc The utility of (11)C-arachidonate PET to study in vivo dopaminergic neurotransmission in humans
    Madhav Thambisetty
    Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Cereb Blood Flow Metab 32:676-84. 2012
    ..1-(11)C]AA PET may be useful for studying disturbances of dopaminergic neurotransmission in conditions such as Parkinson's disease and schizophrenia...