Research Topics
Species | Bruce J TrockSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Detection of life-threatening prostate cancer with prostate-specific antigen velocity during a window of curabilityH Ballentine Carter
Department of Urology, Marburg 403, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
J Natl Cancer Inst 98:1521-7. 2006..The rate at which serum PSA levels change (PSA velocity) may be an important indicator of the presence of life-threatening disease...- Evaluation of GSTP1 and APC methylation as indicators for repeat biopsy in a high-risk cohort of men with negative initial prostate biopsiesBruce J Trock
Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
BJU Int 110:56-62. 2012..When measured in histologically benign prostate biopsy tissue, APC gene hypermethylation was found to have high negative predictive value and high sensitivity. GSTP1 hypermethylation was found to have lower performance than APC... - Cancer/Testis Antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomyTakumi Shiraishi
James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Transl Med 9:153. 2011..The aim of this study was to identify promising CTAs that are associated with prostate cancer (PCa) recurrence following radical prostatectomy (RP)... 
Meta-analysis of soy intake and breast cancer riskBruce J Trock
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
J Natl Cancer Inst 98:459-71. 2006..Thus, rigorous evaluation of available epidemiologic data is necessary before appropriate recommendations can be made, especially for women at high risk of breast cancer or those who have survived the disease...- Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomyBruce J Trock
Brady Urological Institute, Johns Hopkins School of Medicine, 600 N Wolfe St, 546 Phipps Bldg, Baltimore, MD 21287, USA
JAMA 299:2760-9. 2008.... - Importance of tumor location in patients with high preoperative prostate specific antigen levels (greater than 20 ng/ml) treated with radical prostatectomyAhmed Magheli
Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Urol 178:1311-5. 2007.... - Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005Danil V Makarov
Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
Urology 69:1095-101. 2007..To update the 2001 "Partin tables" with a contemporary patient cohort and revised variable categorization, correcting for the effects of stage migration... 
An updated prostate cancer staging nomogram (Partin tables) based on cases from 2006 to 2011John B Eifler
James Buchanan Brady Urological Institute and the Department of Urology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
BJU Int 111:22-9. 2013..To update the 2007 Partin tables in a contemporary patient population...- Effect of treatment with 5-α reductase inhibitors on progression in monitored men with favourable-risk prostate cancerAshley E Ross
James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins Medicinal Institutions, Baltimore, MD, USA
BJU Int 110:651-7. 2012.... - Natural history of pathologically organ-confined (pT2), Gleason score 6 or less, prostate cancer after radical prostatectomyDavid J Hernandez
Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Urology 72:172-6. 2008..We determined the incidence of biochemical recurrence (BR), local recurrence (LR), distant metastasis (DM), and prostate cancer-specific mortality (PCSM) among this low-risk cohort... - Impact of patient age on biochemical recurrence rates following radical prostatectomyAhmed Magheli
Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Urol 178:1933-7; discussion 1937-8. 2007..Stage migration, prostate specific antigen and prostate biopsy pathology are variables that may confound the interpretation of age as an independent prognosticator of outcomes following radical prostatectomy... - Is pelvic osteotomy associated with lower risk of pelvic organ prolapse in postpubertal females with classic bladder exstrophy?Ifeanyi Anusionwu
James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 188:2343-6. 2012..We investigated whether osteotomy is associated with a decreased risk of pelvic organ prolapse in females with classic bladder exstrophy... - The natural history of metastatic progression in men with prostate-specific antigen recurrence after radical prostatectomy: long-term follow-upEmmanuel S Antonarakis
Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center, Brady Urological Institute, Johns Hopkins University, Baltimore, MD 21231, USA
BJU Int 109:32-9. 2012..To describe metastasis-free survival (MFS) in men with prostate-specific antigen (PSA) recurrence following radical prostatectomy, and to define clinical prognostic factors modifying metastatic risk... - Impact of body mass index on biochemical recurrence rates after radical prostatectomy: an analysis utilizing propensity score matchingAhmed Magheli
Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Urology 72:1246-51. 2008..To investigate the significance of body mass index (BMI) as an independent predictor of biochemical recurrence in men treated with surgery for clinically localized adenocarcinoma of the prostate... - The natural history of men treated with deferred androgen deprivation therapy in whom metastatic prostate cancer developed following radical prostatectomyDanil V Makarov
James Buchanan Brady Urological Institute and the Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Urol 179:156-61; discussion 161-2. 2008.... - Medical comorbidities associated with pediatric kidney stone diseaseAnthony J Schaeffer
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Urology 77:195-9. 2011..In adults, kidney stone disease has been associated with medical comorbidities such as HTN, DM, and obesity. Similar analyses have never been performed for the pediatric population... - Prostate specific antigen versus prostate specific antigen density as a prognosticator of pathological characteristics and biochemical recurrence following radical prostatectomyAhmed Magheli
Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 179:1780-4; discussion 1784. 2008..We investigated whether prostate specific antigen density yielded an advantage over total prostate specific antigen for predicting adverse pathological characteristics and disease recurrence following radical prostatectomy... - Relationship between primary Gleason pattern on needle biopsy and clinicopathologic outcomes among men with Gleason score 7 adenocarcinoma of the prostateMark L Gonzalgo
Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Urology 67:115-9. 2006..To examine the relationship among needle biopsy primary grade, prostatectomy grade, and postprostatectomy biochemical recurrence among men with Gleason score 7 disease... - 3-year actuarial biochemical recurrence-free survival following laparoscopic radical prostatectomy: experience from a tertiary referral center in the United StatesChristian P Pavlovich
The Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21224, USA
J Urol 179:917-21; discussion 921-2. 2008..We performed a prospective analysis of pathological and oncological outcomes following laparoscopic radical prostatectomy at a medical center in the United States... - Prostate specific antigen testing among the elderly--when to stop?Edward M Schaeffer
Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, Maryland, USA
J Urol 181:1606-14; discussion 1613-4. 2009..We evaluated the relationship between prostate specific antigen and the risk of aggressive prostate cancer developing in men of various ages... - Treatment decision-making for localized prostate cancer: what younger men choose and whyAbhinav Sidana
Department of Urology, The Johns Hopkins Hospital, Baltimore, Maryland 21231, USA
Prostate 72:58-64. 2012..This study provides insight into information sources consulted and factors dictating treatment decision-making in young prostate cancer patients... - Active surveillance program for prostate cancer: an update of the Johns Hopkins experienceJeffrey J Tosoian
The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, and Johns Hopkins Hospital, Baltimore, MD 21287 2101, USA
J Clin Oncol 29:2185-90. 2011..We assessed outcomes of men with prostate cancer enrolled in active surveillance... - Prostate specific antigen progression in men with lymph node metastases following radical prostatectomy: results of long-term followupGanesh S Palapattu
Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1201, USA
J Urol 172:1860-4. 2004..We examined the clinical outcome of patients with lymph node metastases found at prostatectomy with the goal to identify factors that predict freedom from prostate specific antigen (PSA) progression... - Risk stratification of men choosing surveillance for low risk prostate cancerKenneth S Tseng
Department of Urology, The Johns Hopkins University School of Medicine and The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Urol 183:1779-85. 2010..We sought to predict biopsy progression in men on prostate cancer surveillance... - Incidence and risk factors for inguinal and incisional hernia after laparoscopic radical prostatectomyBrian M Lin
Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
Urology 77:957-62. 2011..It is less clear to what extent minimally invasive radical prostatectomy techniques affect the incidence of hernia development... - Impact of surgical margin status on prostate-cancer-specific mortalityHeather J Chalfin
James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
BJU Int 110:1684-9. 2012..In this cohort, men routinely did not receive adjuvant therapy, affording the unique opportunity to study the long-term implications of a PSM... - The impact of anatomical radical retropubic prostatectomy on cancer control: the 30-year anniversaryJeffrey K Mullins
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 188:2219-24. 2012..We report oncological outcomes of the longest running series of nerve sparing radical retropubic prostatectomy on the 30th anniversary of the inaugural operation... - Should intervening benign tissue be included in the measurement of discontinuous foci of cancer on prostate needle biopsy? Correlation with radical prostatectomy findingsSarah Karram
Department of Pathology, The Johns Hopkins Hospital, 401 N Broadway Street, Baltimore, MD 21231, USA
Am J Surg Pathol 35:1351-5. 2011.... - Interpretation of the prostate-specific antigen history in assessing life-threatening prostate cancerAnna E Kettermann
Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA
BJU Int 106:1284-90; discussion 1290-2. 2010..e. PSA velocity (PSAV). This longitudinal approach might also be extendible to other biomarkers... - What are the outcomes of radical prostatectomy for high-risk prostate cancer?Stacy Loeb
Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
Urology 76:710-4. 2010..These patients are often treated with combined radiation and androgen deprivation therapy, and less is known about the long-term survival in this population after radical prostatectomy (RP)... - Tertiary Gleason patterns and biochemical recurrence after prostatectomy: proposal for a modified Gleason scoring systemBruce J Trock
Department of Urology, The Johns Hopkins Hospital, Baltimore, Maryland 21231, USA
J Urol 182:1364-70. 2009..We investigated the relationship between the tertiary Gleason component in radical prostatectomy specimens and biochemical recurrence in what is to our knowledge the largest single institution cohort to date... - Delayed versus immediate surgical intervention and prostate cancer outcomeChristopher Warlick
Department of Urology, Johns Hopkins University School of Medicine, James Buchanan Brady Urological Institute, Baltimore, MD 21287, USA
J Natl Cancer Inst 98:355-7. 2006..030, .013, and .008, respectively; two-sided chi-square test). Thus, delayed prostate cancer surgery for patients with small, lower-grade prostate cancers does not appear to compromise curability... - Causes of death after radical prostatectomy at a large tertiary centerJohn Bernard Eifler
James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Urol 188:798-801. 2012..We evaluated the cause of death in a large series of patients who underwent radical prostatectomy and compared the rate of death to that of the general American population... - Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?David J Hernandez
James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 173:446-9. 2005..We determined the frequency of positive surgical margins (PSMs) in patients with extraprostatic extension (EPE) in the region of the neurovascular bundle (NVB) who underwent open radical retropubic prostatectomy by 2 experienced surgeons... - Upgrading and downgrading of prostate cancer from biopsy to radical prostatectomy: incidence and predictive factors using the modified Gleason grading system and factoring in tertiary gradesJonathan I Epstein
Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, USA
Eur Urol 61:1019-24. 2012..Prior studies assessing the correlation of Gleason score (GS) at needle biopsy and corresponding radical prostatectomy (RP) predated the use of the modified Gleason scoring system and did not factor in tertiary grade patterns... - The impact of preoperative erectile dysfunction on survival after radical prostatectomyMisop Han
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
BJU Int 106:1612-7. 2010..The underlying pathology for preoperative ED may adversely affect survival following radical prostatectomy (RP). We examined the association between preoperative ED and survival following RP... - Can we stop prostate specific antigen testing 10 years after radical prostatectomy?Stacy Loeb
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Urol 186:500-5. 2011..We examined predictors of late biochemical recurrence, and the relationship between timing of biochemical recurrence and long-term survival outcomes... - Comparison of open and laparoscopic radical prostatectomy outcomes from a surgeon's early experienceAndrew A Wagner
Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA
Urology 70:667-71. 2007..The comparative safety and efficacy of radical retropubic prostatectomy (RRP) and laparoscopic radical prostatectomy (LRP) performed by a newly trained surgeon have not been well documented... - Recurrence-free survival after radical cystectomy of patients downstaged by transurethral resectionMatthew E Nielsen
James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, Maryland 21287 2101, USA
Urology 70:1091-5. 2007.... - A critical analysis of the interpretation of biochemical failure in surgically treated patients using the American Society for Therapeutic Radiation and Oncology criteriaMatthew B Gretzer
The James Buchanan Brady Urological Institute, The Johns Hopkins University Medical Institutions, Baltimore, Maryland, USA
J Urol 168:1419-22. 2002..Until prospective trials comparing these different therapies become available, caution should be exercised when interpreting outcomes between series due to the inherent differences in definition of biochemical failure... - Effect of failed initial closure on bladder growth in children with bladder exstrophyNima Baradaran
Division of Pediatric Urology, Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 186:1450-4. 2011..By measuring successive bladder capacities within the first 5 years of life, we compared the rate of bladder growth in children with failed vs successful initial closure... - Laparoscopic adult donor nephrectomy for pediatric renal transplantationThomas H S Hsu
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
Urology 61:320-2. 2003..No mortality occurred in the pediatric recipients.Laparoscopic donor nephrectomy is well tolerated by the adult donors and appears to provide acceptable recipient and allograft outcomes in the pediatric population... - Complications of renal cryoablation: a single center experienceAbhinav Sidana
The James Buchanan Brady Urological Institute and Department of Radiology CSG, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Urol 184:42-7. 2010..We describe perioperative complications associated with renal cryoablation and identify potential risk factors for certain complications... - Validity of administrative coding in identifying patients with upper urinary tract calculiMichelle J Semins
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 184:190-2. 2010..Administrative databases are increasingly used for epidemiological investigations. We performed a study to assess the validity of ICD-9 codes for upper urinary tract stone disease in an administrative database... - Classification and trends of perioperative morbidities following laparoscopic radical prostatectomyMark L Gonzalgo
Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA
J Urol 174:135-9; discussion 139. 2005..Uniform reporting and grading of surgical complications via a standardized classification system may permit more meaningful comparisons among different centers and surgical techniques... - Anatomical extent of lymph node dissection: impact on men with clinically localized prostate cancerMohamad E Allaf
Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 172:1840-4. 2004..This study evaluates the influence of the anatomical extent of pelvic lymph node dissection performed at radical prostatectomy on lymph node yield, staging accuracy and time to prostate specific antigen progression... - Epidemiologic insights into pediatric kidney stone diseaseBrian R Matlaga
James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Park 2, 600 North Wolfe Street, Baltimore, MD 21287, USA
Urol Res 38:453-7. 2010..Taken all together, these findings suggest that urolithiasis in the young child is a complex systemic disease process... - Laparoscopic partial nephrectomy: effect of warm ischemia on serum creatinineSam B Bhayani
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-2101, USA
J Urol 172:1264-6. 2004..Thus, during LPN efforts to minimize warm ischemia are important but they should not jeopardize cancer control, hemostasis or collecting system closure... - Laparoscopic live donor nephrectomy: trends in donor and recipient morbidity following 381 consecutive casesLi Ming Su
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
Ann Surg 240:358-63. 2004..To review a single-institution 6-year experience with laparoscopic live donor nephrectomy detailing the technical modifications, clinical results, as well as the trends in donor and recipient morbidity... - The effect of ureteral stent placement on post-ureteroscopy complications: a meta-analysisDanil V Makarov
James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21209, USA
Urology 71:796-800. 2008..To determine, by systematic review and meta-analysis of all randomized controlled trials examining ureteral stent placement after ureteroscopy, whether the presence or absence of a stent was associated with postoperative complications... - EPCA-2: a highly specific serum marker for prostate cancerEddy S Leman
Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Urology 69:714-20. 2007..To describe the initial assessment of early prostate cancer antigen (EPCA)-2 as a serum marker for the detection of prostate cancer and to examine its sensitivity and specificity... - The safety of ureteroscopy during pregnancy: a systematic review and meta-analysisMichelle J Semins
James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Urol 181:139-43. 2009..We performed a literature review and analysis to compare the safety of ureteroscopic stone removal during pregnancy with findings from a set of contemporary studies of that procedure in nonpregnant patients... - Impact of renal artery multiplicity on outcomes of renal donors and recipients in laparoscopic donor nephrectomyThomas H S Hsu
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21224, USA
Urology 61:323-7. 2003.... - Application of metabolomics to prostate cancerBruce J Trock
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Urol Oncol 29:572-81. 2011..This review will examine applications of metabolomics to prostate cancer and highlight clinical associations and potential challenges... - Sex prevalence of pediatric kidney stone disease in the United States: an epidemiologic investigationThomas E Novak
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Urology 74:104-7. 2009..To define the sex prevalence of inpatient hospital discharges for pediatric patients diagnosed with upper urinary tract stone disease... - Prognostic significance of preoperative molecular serum analysis in renal cancerMark L Gonzalgo
The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, 150 Marburg Building, 600 North Wolfe Street, Baltimore, MD 21287-2101, USA
Clin Cancer Res 8:1878-81. 2002..Larger prospective randomized trials are needed to validate the clinical utility of this observation... - Long-term pooled analysis of multicenter studies of cooled thermotherapy for benign prostatic hyperplasia results at three months through four yearsBruce J Trock
Division of Epidemiology, Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Urology 63:716-21. 2004..The level of improvement for all three measures remained high at 48 months, indicating that the response is durable... - In vitro fertilization and the cloacal-bladder exstrophy-epispadias complex: is there an association?Hadley M Wood
Division of Epidemiology, Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 169:1512-5. 2003..We sought to determine whether the exstrophy-epispadias complex is overrepresented among children conceived by in vitro fertilization (IVF)... - Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IPDavid Duggan
Division of Genetic Basis of Human Disease, Translational Genomics Research Institute, Phoenix, AZ, USA
J Natl Cancer Inst 99:1836-44. 2007..The consistent finding of a genetic susceptibility to prostate cancer suggests that there are germline sequence variants predisposing individuals to this disease. These variants could be useful in screening and treatment... - Association between two unlinked loci at 8q24 and prostate cancer risk among European AmericansS Lilly Zheng
Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
J Natl Cancer Inst 99:1525-33. 2007..We examined whether multiple independent risk variants exist in this region and whether the strength of observed associations differs as a function of disease aggressiveness... - Cumulative effect of five genetic variants on prostate cancer risk in multiple study populationsJielin Sun
Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Prostate 68:1257-62. 2008..We carried out this study to confirm the finding in two U.S. study populations and perform a combined analysis to obtain a more stable estimate of the odds ratio (OR) for prostate cancer... - Differential effects of leptin on the invasive potential of androgen-dependent and -independent prostate carcinoma cellsDayanand D Deo
Department of Biochemistry, Louisiana State University Health Science Center, New Orleans, LA 70112, USA
J Biomed Biotechnol 2008:163902. 2008..Taken together, these results suggest that leptin mediates the invasive potential of prostate carcinoma cells, and that this effect is dependent on their androgen sensitivity... - Elective laparoscopic partial nephrectomy in patients with tumors >4 cmSoroush Rais-Bahrami
Arthur Smith Institute for Urology, North Shore Long Island Jewish Health System, Long Island, New York 11030, USA
Urology 72:580-3. 2008..To assess the perioperative outcomes of elective laparoscopic partial nephrectomy to treat renal tumors in patients with tumor burdens > 4 cm compared with those with tumor burdens of < or = 4 cm... - Mapping molecular networks using proteomics: a vision for patient-tailored combination therapyEmanuel F Petricoin
US Food and Drug Administration National Cancer Institute Clinical Proteomics Program, Office of Cellular and Gene Therapy, Center for Biologics Evaluation and Research, FDA, Bethesda, MD, USA
J Clin Oncol 23:3614-21. 2005..We provide a vision for individualized combinatorial therapy based on proteomic mapping of phosphorylation end points in clinical tissue material... - Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12Jielin Sun
Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Nat Genet 40:1153-5. 2008..7 x 10(-9) for an allelic test of the seven studies combined. The association at each SNP remained significant after adjustment for the other SNP... - Acceptability of diagnostic tests for breast cancerWenchi Liang
Department of Oncology, Georgetown University Medical Center, Georgetown University, Washington, DC 20007, USA
Breast Cancer Res Treat 79:199-206. 2003..To assess the acceptability of new non-invasive breast cancer diagnostic tests intended to triage women in need of biopsy... - Association of prostate cancer risk variants with clinicopathologic characteristics of the diseaseJianfeng Xu
Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Clin Cancer Res 14:5819-24. 2008..Fifteen independent genetic variants have been implicated in prostate cancer risk by recent genome-wide association studies. However, their association with clinicopathologic features of prostate cancer is uncertain...