Bruce J Trock

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Detection of life-threatening prostate cancer with prostate-specific antigen velocity during a window of curability
    H Ballentine Carter
    Department of Urology, Marburg 403, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Natl Cancer Inst 98:1521-7. 2006
  2. pmc Evaluation of GSTP1 and APC methylation as indicators for repeat biopsy in a high-risk cohort of men with negative initial prostate biopsies
    Bruce J Trock
    Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    BJU Int 110:56-62. 2012
  3. pmc Cancer/Testis Antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy
    Takumi Shiraishi
    James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Transl Med 9:153. 2011
  4. ncbi request reprint Meta-analysis of soy intake and breast cancer risk
    Bruce J Trock
    Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    J Natl Cancer Inst 98:459-71. 2006
  5. pmc Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomy
    Bruce J Trock
    Brady Urological Institute, Johns Hopkins School of Medicine, 600 N Wolfe St, 546 Phipps Bldg, Baltimore, MD 21287, USA
    JAMA 299:2760-9. 2008
  6. ncbi request reprint Importance of tumor location in patients with high preoperative prostate specific antigen levels (greater than 20 ng/ml) treated with radical prostatectomy
    Ahmed Magheli
    Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Urol 178:1311-5. 2007
  7. pmc Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005
    Danil V Makarov
    Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
    Urology 69:1095-101. 2007
  8. pmc An updated prostate cancer staging nomogram (Partin tables) based on cases from 2006 to 2011
    John B Eifler
    James Buchanan Brady Urological Institute and the Department of Urology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    BJU Int 111:22-9. 2013
  9. doi request reprint Effect of treatment with 5-α reductase inhibitors on progression in monitored men with favourable-risk prostate cancer
    Ashley E Ross
    James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins Medicinal Institutions, Baltimore, MD, USA
    BJU Int 110:651-7. 2012
  10. pmc Natural history of pathologically organ-confined (pT2), Gleason score 6 or less, prostate cancer after radical prostatectomy
    David J Hernandez
    Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Urology 72:172-6. 2008

Detail Information

Publications71

  1. pmc Detection of life-threatening prostate cancer with prostate-specific antigen velocity during a window of curability
    H Ballentine Carter
    Department of Urology, Marburg 403, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Natl Cancer Inst 98:1521-7. 2006
    ..The rate at which serum PSA levels change (PSA velocity) may be an important indicator of the presence of life-threatening disease...
  2. pmc Evaluation of GSTP1 and APC methylation as indicators for repeat biopsy in a high-risk cohort of men with negative initial prostate biopsies
    Bruce J Trock
    Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    BJU Int 110:56-62. 2012
    ..When measured in histologically benign prostate biopsy tissue, APC gene hypermethylation was found to have high negative predictive value and high sensitivity. GSTP1 hypermethylation was found to have lower performance than APC...
  3. pmc Cancer/Testis Antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy
    Takumi Shiraishi
    James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Transl Med 9:153. 2011
    ..The aim of this study was to identify promising CTAs that are associated with prostate cancer (PCa) recurrence following radical prostatectomy (RP)...
  4. ncbi request reprint Meta-analysis of soy intake and breast cancer risk
    Bruce J Trock
    Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    J Natl Cancer Inst 98:459-71. 2006
    ..Thus, rigorous evaluation of available epidemiologic data is necessary before appropriate recommendations can be made, especially for women at high risk of breast cancer or those who have survived the disease...
  5. pmc Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomy
    Bruce J Trock
    Brady Urological Institute, Johns Hopkins School of Medicine, 600 N Wolfe St, 546 Phipps Bldg, Baltimore, MD 21287, USA
    JAMA 299:2760-9. 2008
    ....
  6. ncbi request reprint Importance of tumor location in patients with high preoperative prostate specific antigen levels (greater than 20 ng/ml) treated with radical prostatectomy
    Ahmed Magheli
    Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Urol 178:1311-5. 2007
    ....
  7. pmc Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005
    Danil V Makarov
    Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
    Urology 69:1095-101. 2007
    ..To update the 2001 "Partin tables" with a contemporary patient cohort and revised variable categorization, correcting for the effects of stage migration...
  8. pmc An updated prostate cancer staging nomogram (Partin tables) based on cases from 2006 to 2011
    John B Eifler
    James Buchanan Brady Urological Institute and the Department of Urology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    BJU Int 111:22-9. 2013
    ..To update the 2007 Partin tables in a contemporary patient population...
  9. doi request reprint Effect of treatment with 5-α reductase inhibitors on progression in monitored men with favourable-risk prostate cancer
    Ashley E Ross
    James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins Medicinal Institutions, Baltimore, MD, USA
    BJU Int 110:651-7. 2012
    ....
  10. pmc Natural history of pathologically organ-confined (pT2), Gleason score 6 or less, prostate cancer after radical prostatectomy
    David J Hernandez
    Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Urology 72:172-6. 2008
    ..We determined the incidence of biochemical recurrence (BR), local recurrence (LR), distant metastasis (DM), and prostate cancer-specific mortality (PCSM) among this low-risk cohort...
  11. ncbi request reprint Impact of patient age on biochemical recurrence rates following radical prostatectomy
    Ahmed Magheli
    Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Urol 178:1933-7; discussion 1937-8. 2007
    ..Stage migration, prostate specific antigen and prostate biopsy pathology are variables that may confound the interpretation of age as an independent prognosticator of outcomes following radical prostatectomy...
  12. doi request reprint Is pelvic osteotomy associated with lower risk of pelvic organ prolapse in postpubertal females with classic bladder exstrophy?
    Ifeanyi Anusionwu
    James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 188:2343-6. 2012
    ..We investigated whether osteotomy is associated with a decreased risk of pelvic organ prolapse in females with classic bladder exstrophy...
  13. pmc The natural history of metastatic progression in men with prostate-specific antigen recurrence after radical prostatectomy: long-term follow-up
    Emmanuel S Antonarakis
    Prostate Cancer Research Program, Sidney Kimmel Comprehensive Cancer Center, Brady Urological Institute, Johns Hopkins University, Baltimore, MD 21231, USA
    BJU Int 109:32-9. 2012
    ..To describe metastasis-free survival (MFS) in men with prostate-specific antigen (PSA) recurrence following radical prostatectomy, and to define clinical prognostic factors modifying metastatic risk...
  14. pmc Impact of body mass index on biochemical recurrence rates after radical prostatectomy: an analysis utilizing propensity score matching
    Ahmed Magheli
    Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Urology 72:1246-51. 2008
    ..To investigate the significance of body mass index (BMI) as an independent predictor of biochemical recurrence in men treated with surgery for clinically localized adenocarcinoma of the prostate...
  15. ncbi request reprint The natural history of men treated with deferred androgen deprivation therapy in whom metastatic prostate cancer developed following radical prostatectomy
    Danil V Makarov
    James Buchanan Brady Urological Institute and the Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Urol 179:156-61; discussion 161-2. 2008
    ....
  16. pmc Prostate specific antigen versus prostate specific antigen density as a prognosticator of pathological characteristics and biochemical recurrence following radical prostatectomy
    Ahmed Magheli
    Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 179:1780-4; discussion 1784. 2008
    ..We investigated whether prostate specific antigen density yielded an advantage over total prostate specific antigen for predicting adverse pathological characteristics and disease recurrence following radical prostatectomy...
  17. doi request reprint Medical comorbidities associated with pediatric kidney stone disease
    Anthony J Schaeffer
    James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Urology 77:195-9. 2011
    ..In adults, kidney stone disease has been associated with medical comorbidities such as HTN, DM, and obesity. Similar analyses have never been performed for the pediatric population...
  18. pmc Laparoscopic and robotic radical prostatectomy outcomes in obese and extremely obese men
    Debasish Sundi
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Urology 82:600-5. 2013
    ..To evaluate the operative and pathologic outcomes of laparoscopic radical prostatectomy and robot-assisted radical prostatectomy in men with progressive changes in body mass index (BMI) category...
  19. doi request reprint Pathological outcomes in men with low risk and very low risk prostate cancer: implications on the practice of active surveillance
    Jeffrey J Tosoian
    Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, Maryland
    J Urol 190:1218-22. 2013
    ..We assessed oncologic outcomes at surgery in men with low risk and very low risk prostate cancer who were candidates for active surveillance...
  20. ncbi request reprint Relationship between primary Gleason pattern on needle biopsy and clinicopathologic outcomes among men with Gleason score 7 adenocarcinoma of the prostate
    Mark L Gonzalgo
    Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Urology 67:115-9. 2006
    ..To examine the relationship among needle biopsy primary grade, prostatectomy grade, and postprostatectomy biochemical recurrence among men with Gleason score 7 disease...
  21. doi request reprint Active surveillance program for prostate cancer: an update of the Johns Hopkins experience
    Jeffrey J Tosoian
    The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, and Johns Hopkins Hospital, Baltimore, MD 21287 2101, USA
    J Clin Oncol 29:2185-90. 2011
    ..We assessed outcomes of men with prostate cancer enrolled in active surveillance...
  22. pmc Prostate specific antigen testing among the elderly--when to stop?
    Edward M Schaeffer
    Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Urol 181:1606-14; discussion 1613-4. 2009
    ..We evaluated the relationship between prostate specific antigen and the risk of aggressive prostate cancer developing in men of various ages...
  23. doi request reprint Treatment decision-making for localized prostate cancer: what younger men choose and why
    Abhinav Sidana
    Department of Urology, The Johns Hopkins Hospital, Baltimore, Maryland 21231, USA
    Prostate 72:58-64. 2012
    ..This study provides insight into information sources consulted and factors dictating treatment decision-making in young prostate cancer patients...
  24. doi request reprint Nightly vs on-demand sildenafil for penile rehabilitation after minimally invasive nerve-sparing radical prostatectomy: results of a randomized double-blind trial with placebo
    Christian P Pavlovich
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    BJU Int 112:844-51. 2013
    ..To clarify the role of phosphodiesterase type 5 (PDE5) inhibitors in post-prostatectomy penile rehabilitation (PPPR). To compare nightly and on-demand use of PDE5 inhibitors after nerve-sparing minimally invasive radical prostatectomy (RP)...
  25. doi request reprint 3-year actuarial biochemical recurrence-free survival following laparoscopic radical prostatectomy: experience from a tertiary referral center in the United States
    Christian P Pavlovich
    The Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21224, USA
    J Urol 179:917-21; discussion 921-2. 2008
    ..We performed a prospective analysis of pathological and oncological outcomes following laparoscopic radical prostatectomy at a medical center in the United States...
  26. ncbi request reprint Prostate specific antigen progression in men with lymph node metastases following radical prostatectomy: results of long-term followup
    Ganesh S Palapattu
    Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1201, USA
    J Urol 172:1860-4. 2004
    ..We examined the clinical outcome of patients with lymph node metastases found at prostatectomy with the goal to identify factors that predict freedom from prostate specific antigen (PSA) progression...
  27. doi request reprint Incidence and risk factors for inguinal and incisional hernia after laparoscopic radical prostatectomy
    Brian M Lin
    Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
    Urology 77:957-62. 2011
    ..It is less clear to what extent minimally invasive radical prostatectomy techniques affect the incidence of hernia development...
  28. pmc Risk stratification of men choosing surveillance for low risk prostate cancer
    Kenneth S Tseng
    Department of Urology, The Johns Hopkins University School of Medicine and The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Urol 183:1779-85. 2010
    ..We sought to predict biopsy progression in men on prostate cancer surveillance...
  29. pmc Impact of surgical margin status on prostate-cancer-specific mortality
    Heather J Chalfin
    James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    BJU Int 110:1684-9. 2012
    ..In this cohort, men routinely did not receive adjuvant therapy, affording the unique opportunity to study the long-term implications of a PSM...
  30. doi request reprint The impact of anatomical radical retropubic prostatectomy on cancer control: the 30-year anniversary
    Jeffrey K Mullins
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 188:2219-24. 2012
    ..We report oncological outcomes of the longest running series of nerve sparing radical retropubic prostatectomy on the 30th anniversary of the inaugural operation...
  31. doi request reprint Should intervening benign tissue be included in the measurement of discontinuous foci of cancer on prostate needle biopsy? Correlation with radical prostatectomy findings
    Sarah Karram
    Department of Pathology, The Johns Hopkins Hospital, 401 N Broadway Street, Baltimore, MD 21231, USA
    Am J Surg Pathol 35:1351-5. 2011
    ....
  32. pmc Delayed versus immediate surgical intervention and prostate cancer outcome
    Christopher Warlick
    Department of Urology, Johns Hopkins University School of Medicine, James Buchanan Brady Urological Institute, Baltimore, MD 21287, USA
    J Natl Cancer Inst 98:355-7. 2006
    ..030, .013, and .008, respectively; two-sided chi-square test). Thus, delayed prostate cancer surgery for patients with small, lower-grade prostate cancers does not appear to compromise curability...
  33. pmc Interpretation of the prostate-specific antigen history in assessing life-threatening prostate cancer
    Anna E Kettermann
    Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA
    BJU Int 106:1284-90; discussion 1290-2. 2010
    ..e. PSA velocity (PSAV). This longitudinal approach might also be extendible to other biomarkers...
  34. pmc What are the outcomes of radical prostatectomy for high-risk prostate cancer?
    Stacy Loeb
    Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
    Urology 76:710-4. 2010
    ..These patients are often treated with combined radiation and androgen deprivation therapy, and less is known about the long-term survival in this population after radical prostatectomy (RP)...
  35. doi request reprint Tertiary Gleason patterns and biochemical recurrence after prostatectomy: proposal for a modified Gleason scoring system
    Bruce J Trock
    Department of Urology, The Johns Hopkins Hospital, Baltimore, Maryland 21231, USA
    J Urol 182:1364-70. 2009
    ..We investigated the relationship between the tertiary Gleason component in radical prostatectomy specimens and biochemical recurrence in what is to our knowledge the largest single institution cohort to date...
  36. doi request reprint Multiphasic enhancement patterns of small renal masses (≤4 cm) on preoperative computed tomography: utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma
    Phillip M Pierorazio
    James Buchanan Brady Urological Institute, Johns Hopkins Medicine, Baltimore, MD, USA
    Urology 81:1265-71. 2013
    ..To analyze the enhancement patterns of small renal masses (SRMs) during 4-phase computed tomography (CT) imaging to predict histology...
  37. doi request reprint Causes of death after radical prostatectomy at a large tertiary center
    John Bernard Eifler
    James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Urol 188:798-801. 2012
    ..We evaluated the cause of death in a large series of patients who underwent radical prostatectomy and compared the rate of death to that of the general American population...
  38. ncbi request reprint Radical retropubic prostatectomy. How often do experienced surgeons have positive surgical margins when there is extraprostatic extension in the region of the neurovascular bundle?
    David J Hernandez
    James Buchanan Brady Urological Institute and The Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 173:446-9. 2005
    ..We determined the frequency of positive surgical margins (PSMs) in patients with extraprostatic extension (EPE) in the region of the neurovascular bundle (NVB) who underwent open radical retropubic prostatectomy by 2 experienced surgeons...
  39. doi request reprint Upgrading and downgrading of prostate cancer from biopsy to radical prostatectomy: incidence and predictive factors using the modified Gleason grading system and factoring in tertiary grades
    Jonathan I Epstein
    Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, USA
    Eur Urol 61:1019-24. 2012
    ..Prior studies assessing the correlation of Gleason score (GS) at needle biopsy and corresponding radical prostatectomy (RP) predated the use of the modified Gleason scoring system and did not factor in tertiary grade patterns...
  40. doi request reprint Can we stop prostate specific antigen testing 10 years after radical prostatectomy?
    Stacy Loeb
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Urol 186:500-5. 2011
    ..We examined predictors of late biochemical recurrence, and the relationship between timing of biochemical recurrence and long-term survival outcomes...
  41. ncbi request reprint Comparison of open and laparoscopic radical prostatectomy outcomes from a surgeon's early experience
    Andrew A Wagner
    Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA
    Urology 70:667-71. 2007
    ..The comparative safety and efficacy of radical retropubic prostatectomy (RRP) and laparoscopic radical prostatectomy (LRP) performed by a newly trained surgeon have not been well documented...
  42. ncbi request reprint Recurrence-free survival after radical cystectomy of patients downstaged by transurethral resection
    Matthew E Nielsen
    James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, Maryland 21287 2101, USA
    Urology 70:1091-5. 2007
    ....
  43. pmc The impact of preoperative erectile dysfunction on survival after radical prostatectomy
    Misop Han
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    BJU Int 106:1612-7. 2010
    ..The underlying pathology for preoperative ED may adversely affect survival following radical prostatectomy (RP). We examined the association between preoperative ED and survival following RP...
  44. ncbi request reprint A critical analysis of the interpretation of biochemical failure in surgically treated patients using the American Society for Therapeutic Radiation and Oncology criteria
    Matthew B Gretzer
    The James Buchanan Brady Urological Institute, The Johns Hopkins University Medical Institutions, Baltimore, Maryland, USA
    J Urol 168:1419-22. 2002
    ..We evaluate how the American Society for Therapeutic Radiation and Oncology (ASTRO) criteria affect the interpretation of failure when applied to radical prostatectomy...
  45. doi request reprint Effect of failed initial closure on bladder growth in children with bladder exstrophy
    Nima Baradaran
    Division of Pediatric Urology, Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 186:1450-4. 2011
    ..By measuring successive bladder capacities within the first 5 years of life, we compared the rate of bladder growth in children with failed vs successful initial closure...
  46. ncbi request reprint Laparoscopic adult donor nephrectomy for pediatric renal transplantation
    Thomas H S Hsu
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
    Urology 61:320-2. 2003
    ..No mortality occurred in the pediatric recipients. Laparoscopic donor nephrectomy is well tolerated by the adult donors and appears to provide acceptable recipient and allograft outcomes in the pediatric population...
  47. ncbi request reprint Classification and trends of perioperative morbidities following laparoscopic radical prostatectomy
    Mark L Gonzalgo
    Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA
    J Urol 174:135-9; discussion 139. 2005
    ..We classified and assessed trends in the incidence, severity and management of perioperative morbidity following laparoscopic radical prostatectomy (LRP)...
  48. doi request reprint Epidemiologic insights into pediatric kidney stone disease
    Brian R Matlaga
    James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Park 2, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Urol Res 38:453-7. 2010
    ..Taken all together, these findings suggest that urolithiasis in the young child is a complex systemic disease process...
  49. doi request reprint Complications of renal cryoablation: a single center experience
    Abhinav Sidana
    The James Buchanan Brady Urological Institute and Department of Radiology CSG, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Urol 184:42-7. 2010
    ..We describe perioperative complications associated with renal cryoablation and identify potential risk factors for certain complications...
  50. doi request reprint Validity of administrative coding in identifying patients with upper urinary tract calculi
    Michelle J Semins
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 184:190-2. 2010
    ..Administrative databases are increasingly used for epidemiological investigations. We performed a study to assess the validity of ICD-9 codes for upper urinary tract stone disease in an administrative database...
  51. ncbi request reprint Laparoscopic partial nephrectomy: effect of warm ischemia on serum creatinine
    Sam B Bhayani
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
    J Urol 172:1264-6. 2004
    ..However, limited data are available regarding the effect of warm ischemic time on postoperative renal function. We assessed the effect of variable durations of warm ischemia on long-term renal function in patients undergoing LPN...
  52. ncbi request reprint Anatomical extent of lymph node dissection: impact on men with clinically localized prostate cancer
    Mohamad E Allaf
    Department of Urology, The Johns Hopkins University School of Medicine, The James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 172:1840-4. 2004
    ..This study evaluates the influence of the anatomical extent of pelvic lymph node dissection performed at radical prostatectomy on lymph node yield, staging accuracy and time to prostate specific antigen progression...
  53. pmc Laparoscopic live donor nephrectomy: trends in donor and recipient morbidity following 381 consecutive cases
    Li Ming Su
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
    Ann Surg 240:358-63. 2004
    ..To review a single-institution 6-year experience with laparoscopic live donor nephrectomy detailing the technical modifications, clinical results, as well as the trends in donor and recipient morbidity...
  54. doi request reprint The safety of ureteroscopy during pregnancy: a systematic review and meta-analysis
    Michelle J Semins
    James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Urol 181:139-43. 2009
    ..We performed a literature review and analysis to compare the safety of ureteroscopic stone removal during pregnancy with findings from a set of contemporary studies of that procedure in nonpregnant patients...
  55. doi request reprint The effect of ureteral stent placement on post-ureteroscopy complications: a meta-analysis
    Danil V Makarov
    James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21209, USA
    Urology 71:796-800. 2008
    ..To determine, by systematic review and meta-analysis of all randomized controlled trials examining ureteral stent placement after ureteroscopy, whether the presence or absence of a stent was associated with postoperative complications...
  56. ncbi request reprint EPCA-2: a highly specific serum marker for prostate cancer
    Eddy S Leman
    Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Urology 69:714-20. 2007
    ..To describe the initial assessment of early prostate cancer antigen (EPCA)-2 as a serum marker for the detection of prostate cancer and to examine its sensitivity and specificity...
  57. ncbi request reprint Impact of renal artery multiplicity on outcomes of renal donors and recipients in laparoscopic donor nephrectomy
    Thomas H S Hsu
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21224, USA
    Urology 61:323-7. 2003
    ..To review our laparoscopic donor nephrectomy experience to determine the impact of multiple renal arteries on renal donor and recipient outcomes. Multiple renal arteries can present a challenge during live laparoscopic donor nephrectomy...
  58. pmc Application of metabolomics to prostate cancer
    Bruce J Trock
    Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Urol Oncol 29:572-81. 2011
    ..This review will examine applications of metabolomics to prostate cancer and highlight clinical associations and potential challenges...
  59. doi request reprint Sex prevalence of pediatric kidney stone disease in the United States: an epidemiologic investigation
    Thomas E Novak
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Urology 74:104-7. 2009
    ..To define the sex prevalence of inpatient hospital discharges for pediatric patients diagnosed with upper urinary tract stone disease...
  60. ncbi request reprint Prognostic significance of preoperative molecular serum analysis in renal cancer
    Mark L Gonzalgo
    The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, 150 Marburg Building, 600 North Wolfe Street, Baltimore, MD 21287 2101, USA
    Clin Cancer Res 8:1878-81. 2002
    ....
  61. ncbi request reprint Long-term pooled analysis of multicenter studies of cooled thermotherapy for benign prostatic hyperplasia results at three months through four years
    Bruce J Trock
    Division of Epidemiology, Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Urology 63:716-21. 2004
    ..To determine the long-term efficacy of cooled thermotherapy in the treatment of lower urinary tract symptoms of clinical benign prostatic hyperplasia...
  62. ncbi request reprint In vitro fertilization and the cloacal-bladder exstrophy-epispadias complex: is there an association?
    Hadley M Wood
    Division of Epidemiology, Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Urol 169:1512-5. 2003
    ..We sought to determine whether the exstrophy-epispadias complex is overrepresented among children conceived by in vitro fertilization (IVF)...
  63. ncbi request reprint Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP
    David Duggan
    Division of Genetic Basis of Human Disease, Translational Genomics Research Institute, Phoenix, AZ, USA
    J Natl Cancer Inst 99:1836-44. 2007
    ..The consistent finding of a genetic susceptibility to prostate cancer suggests that there are germline sequence variants predisposing individuals to this disease. These variants could be useful in screening and treatment...
  64. pmc Cumulative effect of five genetic variants on prostate cancer risk in multiple study populations
    Jielin Sun
    Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Prostate 68:1257-62. 2008
    ..We carried out this study to confirm the finding in two U.S. study populations and perform a combined analysis to obtain a more stable estimate of the odds ratio (OR) for prostate cancer...
  65. ncbi request reprint Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans
    S Lilly Zheng
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Natl Cancer Inst 99:1525-33. 2007
    ..We examined whether multiple independent risk variants exist in this region and whether the strength of observed associations differs as a function of disease aggressiveness...
  66. pmc Differential effects of leptin on the invasive potential of androgen-dependent and -independent prostate carcinoma cells
    Dayanand D Deo
    Department of Biochemistry, Louisiana State University Health Science Center, New Orleans, LA 70112, USA
    J Biomed Biotechnol 2008:163902. 2008
    ..Taken together, these results suggest that leptin mediates the invasive potential of prostate carcinoma cells, and that this effect is dependent on their androgen sensitivity...
  67. doi request reprint Elective laparoscopic partial nephrectomy in patients with tumors >4 cm
    Soroush Rais-Bahrami
    Arthur Smith Institute for Urology, North Shore Long Island Jewish Health System, Long Island, New York 11030, USA
    Urology 72:580-3. 2008
    ..To assess the perioperative outcomes of elective laparoscopic partial nephrectomy to treat renal tumors in patients with tumor burdens > 4 cm compared with those with tumor burdens of < or = 4 cm...
  68. ncbi request reprint Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy
    Emanuel F Petricoin
    US Food and Drug Administration National Cancer Institute Clinical Proteomics Program, Office of Cellular and Gene Therapy, Center for Biologics Evaluation and Research, FDA, Bethesda, MD, USA
    J Clin Oncol 23:3614-21. 2005
    ..We provide a vision for individualized combinatorial therapy based on proteomic mapping of phosphorylation end points in clinical tissue material...
  69. pmc Association of prostate cancer risk variants with clinicopathologic characteristics of the disease
    Jianfeng Xu
    Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Clin Cancer Res 14:5819-24. 2008
    ..Fifteen independent genetic variants have been implicated in prostate cancer risk by recent genome-wide association studies. However, their association with clinicopathologic features of prostate cancer is uncertain...
  70. pmc Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12
    Jielin Sun
    Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Nat Genet 40:1153-5. 2008
    ..7 x 10(-9) for an allelic test of the seven studies combined. The association at each SNP remained significant after adjustment for the other SNP...
  71. ncbi request reprint Acceptability of diagnostic tests for breast cancer
    Wenchi Liang
    Department of Oncology, Georgetown University Medical Center, Georgetown University, Washington, DC 20007, USA
    Breast Cancer Res Treat 79:199-206. 2003
    ..To assess the acceptability of new non-invasive breast cancer diagnostic tests intended to triage women in need of biopsy...