Research Topics
| Cornelia L TrimbleSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotypeCornelia L Trimble
Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Clin Cancer Res 11:4717-23. 2005..We carried out a prospective observational cohort study evaluating known, quantifiable prognostic variables of clinical behavior in women with high-grade cervical lesions...
Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3Cornelia L Trimble
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Cancer Immunol Immunother 59:799-803. 2010..This finding suggests that, in the setting of natural infection, immune responses which are involved in elimination of cervical dysplastic epithelium are not represented to any great extent in the systemic circulation...
Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epitheliumCornelia L Trimble
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Immunol 185:7107-14. 2010..These findings suggest that dysregulated expression of vascular adhesion molecules plays a role in immune evasion very early in the course of HPV disease...
A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3Cornelia L Trimble
Department of Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Clin Cancer Res 15:361-7. 2009..To evaluate the safety and immunogenicity of a therapeutic human papillomavirus (HPV)16 DNA vaccine administered to women with HPV16+cervical intraepithelial neoplasia (CIN)2/3...
Disparities in human papillomavirus vaccine completion among vaccine initiatorsBetty Chou
Departments of Gynecology and Obstetrics, Oncology, and Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Obstet Gynecol 118:14-20. 2011..To estimate rates of completing the full three-dose prophylactic human papillomavirus (HPV) vaccination regimen in patients who initiated the series and to identify variables associated with not completing vaccination...
Effectiveness of screening for cervical cancer in an inpatient hospital settingCornelia L Trimble
Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD 21287, USA
Obstet Gynecol 103:310-6. 2004..To estimate the effectiveness of an inpatient, hospital-based cervical cancer screening program at a single institution...
The PapSpin: a reasonable alternative to other, more expensive liquid-based Papanicolaou testsDorothy L Rosenthal
Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 6940, USA
Cancer 108:137-43. 2006....
New technologies for cervical cancer screeningAlaina J Brown
Department of Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Best Pract Res Clin Obstet Gynaecol 26:233-42. 2012..These methods show promise in changing the way that current cervical cancer screening is undertaken in low-and high-resource settings...
Development of therapeutic HPV vaccinesCornelia L Trimble
Johns Hopkins University Hospital, Baltimore, MD, USA
Lancet Oncol 10:975-80. 2009..In this Review, we discuss recent progress in this field and priorities for future clinical investigations...
Human papillomavirus vaccination should be offered to young males: CounterpointCornelia L Trimble
The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Cancer Epidemiol Biomarkers Prev 17:809. 2008
Prospects for therapeutic HPV vaccinesCornelia L Trimble
Department of Gynecology and Obstetrics, The Johns Hopkins Hospital, 600 North Wolfe St, Phipps 255, Baltimore, MD 21287, USA
Gynecol Oncol 99:S249-50. 2005
Impact of payer status on treatment of cervical cancer at a tertiary referral centerKimberly L Levinson
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Gynecol Oncol 122:324-7. 2011..The study aims to determine the impact of payer status on the likelihood of receiving definitive treatment for invasive cervical cancer at a tertiary medical center...
Active and passive cigarette smoking and the risk of cervical neoplasiaCornelia L Trimble
Department of Obstetrics and Gynecology, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Obstet Gynecol 105:174-81. 2005..The results of this long-term, prospective cohort study corroborate the association between active cigarette smoking and cervical neoplasia and provide evidence that passive smoking is a risk factor for cervical neoplasia...
Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasionYali Zhai
Department of Pathology, The University of Michigan Medical School, Ann Arbor, MI 48109 2200, USA
Cancer Res 67:10163-72. 2007..Other genes with differential expression in invasive SCC versus HSIL may contribute to tumor progression or may be useful as markers for cancer diagnosis or progression risk...
