James Tielsch

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. ncbi Neonatal hypothermia and associated risk factors among newborns of southern Nepal
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N, Wolfe Street, Baltimore, MD 21205, USA
    BMC Med 8:43. 2010
  2. ncbi Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trial
    James M Tielsch
    Center for Human Nutrition and the Sight and Life Institute, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Lancet 367:144-52. 2006
  3. ncbi Exposure to indoor biomass fuel and tobacco smoke and risk of adverse reproductive outcomes, mortality, respiratory morbidity and growth among newborn infants in south India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Int J Epidemiol 38:1351-63. 2009
  4. ncbi Maternal night blindness during pregnancy is associated with low birthweight, morbidity, and poor growth in South India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 138:787-92. 2008
  5. ncbi Newborn vitamin A dosing reduces the case fatality but not incidence of common childhood morbidities in South India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 137:2470-4. 2007
  6. ncbi Impact of newborn skin-cleansing with chlorhexidine on neonatal mortality in southern Nepal: a community-based, cluster-randomized trial
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Pediatrics 119:e330-40. 2007
  7. ncbi Impact of ivermectin on illness and disability associated with onchocerciasis
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Trop Med Int Health 9:A45-56. 2004
  8. ncbi Maternal and birth attendant hand washing and neonatal mortality in southern Nepal
    Victor Rhee
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205 2103, USA
    Arch Pediatr Adolesc Med 162:603-8. 2008
  9. ncbi Iron supplementation in early childhood: health benefits and risks
    Lora L Iannotti
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Clin Nutr 84:1261-76. 2006
  10. ncbi Low-dose daily iron supplementation for 12 months does not increase the prevalence of malarial infection or density of parasites in young Zanzibari children
    Tsedal Mebrahtu
    Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Nutr 134:3037-41. 2004

Research Grants

Detail Information

Publications86

  1. ncbi Neonatal hypothermia and associated risk factors among newborns of southern Nepal
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N, Wolfe Street, Baltimore, MD 21205, USA
    BMC Med 8:43. 2010
    ..Estimates of association between neonatal hypothermia in the community and risk factors are needed to guide the design of interventions to reduce exposure...
  2. ncbi Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trial
    James M Tielsch
    Center for Human Nutrition and the Sight and Life Institute, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Lancet 367:144-52. 2006
    ..Supplementation with iron and folic acid alleviates severe anaemia and enhances neurodevelopment in deficient populations, but little is known about the risks of mortality and morbidity associated with supplementation...
  3. ncbi Exposure to indoor biomass fuel and tobacco smoke and risk of adverse reproductive outcomes, mortality, respiratory morbidity and growth among newborn infants in south India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Int J Epidemiol 38:1351-63. 2009
    ..We assessed the association between exposure to biomass fuel sources and second-hand tobacco smoke (SHTS) in the home and adverse health outcomes in early infancy in a population in rural south India...
  4. ncbi Maternal night blindness during pregnancy is associated with low birthweight, morbidity, and poor growth in South India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 138:787-92. 2008
    ..05, 1.34). Maternal night blindness was not associated with 6-mo infant mortality or wasting at 6 mo. This study demonstrates that there are important consequences to the infant of maternal vitamin A deficiency during pregnancy...
  5. ncbi Newborn vitamin A dosing reduces the case fatality but not incidence of common childhood morbidities in South India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 137:2470-4. 2007
    ..This trial demonstrated that the reduction in overall mortality due to newborn vitamin A dosing was driven primarily by a reduction in case fatality among infants...
  6. ncbi Impact of newborn skin-cleansing with chlorhexidine on neonatal mortality in southern Nepal: a community-based, cluster-randomized trial
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Pediatrics 119:e330-40. 2007
    ..Our objective was to assess the efficacy of a 1-time skin-cleansing of newborn infants with 0.25% chlorhexidine on neonatal mortality...
  7. ncbi Impact of ivermectin on illness and disability associated with onchocerciasis
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Trop Med Int Health 9:A45-56. 2004
    ..While there are significant barriers to continued program success, focussed attention on expanding and improving community-directed ivermectin distribution is likely to lead to further progress against this resilient infection...
  8. ncbi Maternal and birth attendant hand washing and neonatal mortality in southern Nepal
    Victor Rhee
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205 2103, USA
    Arch Pediatr Adolesc Med 162:603-8. 2008
    ..More than 95% of neonatal deaths occur in developing countries, approximately 50% at home. Few data are available on the impact of hand-washing practices by birth attendants or caretakers on neonatal mortality...
  9. ncbi Iron supplementation in early childhood: health benefits and risks
    Lora L Iannotti
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Clin Nutr 84:1261-76. 2006
    ..More research is needed in populations affected by HIV and tuberculosis. Iron supplementation in preventive programs may need to be targeted through identification of iron-deficient children...
  10. ncbi Low-dose daily iron supplementation for 12 months does not increase the prevalence of malarial infection or density of parasites in young Zanzibari children
    Tsedal Mebrahtu
    Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Nutr 134:3037-41. 2004
    ..We conclude that in this environment of high malaria transmission, daily oral low-dose supplementation of iron for 12 mo did not affect the prevalence of malaria infection or parasite density...
  11. ncbi Zinc modifies the association between nasopharyngeal Streptococcus pneumoniae carriage and risk of acute lower respiratory infection among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 138:2462-7. 2008
    ..09; P = 0.006) than in the zinc group (AMOR = 2.77; P = 0.288). These findings suggest that zinc prophylaxis may protect children against ALRI associated with carriage of Spn and that the effect may differ by infectious etiology...
  12. ncbi Potential role of traditional birth attendants in neonatal healthcare in rural southern Nepal
    Tina Y Falle
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, E8646, Baltimore, MD 21205, USA
    J Health Popul Nutr 27:53-61. 2009
    ..Continuing efforts to define the role of TBAs may benefit from an emphasis on their potential as active promoters of essential newborn care...
  13. ncbi Exploring the effects of an "everyday" activity program on executive function and memory in older adults: Experience Corps
    Michelle C Carlson
    Department of Mental Health, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
    Gerontologist 48:793-801. 2008
    ..This study sought to demonstrate in a short-term pilot randomized trial that such an activity program improves components of cognition critical to independent function among sedentary older adults at greatest risk...
  14. ncbi Unexpectedly low prevalence of Helicobacter pylori infection among pregnant women on Pemba Island, Zanzibar
    Tamer H Farag
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins, University, Baltimore, MD, USA
    Trans R Soc Trop Med Hyg 101:915-22. 2007
    ..The reason for very low prevalence should be investigated further because the discovery of bacterial or dietary factors that limit infection in this population could have useful public health applications...
  15. ncbi Helicobacter pylori infection is associated with severe anemia of pregnancy on Pemba Island, Zanzibar
    Tamer H Farag
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Am J Trop Med Hyg 76:541-8. 2007
    ..Further research is needed to establish causality because high worldwide prevalence means that even a small associated risk would be of public health significance...
  16. ncbi Risk of mortality associated with neonatal hypothermia in southern Nepal
    Luke C Mullany
    Department of International Health, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Arch Pediatr Adolesc Med 164:650-6. 2010
    ..To quantify the neonatal mortality/hypothermia relationship and develop evidence-based cutoffs for global definitions of neonatal hypothermia...
  17. ncbi Pregnancy-related mortality in southern Nepal between 2001 and 2006: independent estimates from a prospective, population-based cohort and a direct sisterhood survey
    David W Wee
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Am J Epidemiol 172:855-60. 2010
    ..Access to life-saving maternal health interventions remains low in rural Nepal, and continued efforts are necessary to ensure equitable and country-wide progress toward Millennium Development Goal 5...
  18. ncbi Impact of umbilical cord cleansing with 4.0% chlorhexidine on time to cord separation among newborns in southern Nepal: a cluster-randomized, community-based trial
    Luke C Mullany
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, W5009, Baltimore, MD 21211, USA
    Pediatrics 118:1864-71. 2006
    ..0% chlorhexidine on omphalitis and mortality risk, we aimed to describe the distribution of times to separation and the impact of topical chlorhexidine treatment on cord-separation times...
  19. ncbi Risk factors for umbilical cord infection among newborns of southern Nepal
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
    Am J Epidemiol 165:203-11. 2007
    ..In addition to topical antiseptics, simple, low-cost interventions such as hand washing, skin-to-skin contact, and avoiding unclean cord applications should be promoted by community-based health workers...
  20. ncbi Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countries
    Luke C Mullany
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21211, USA
    Pediatr Infect Dis J 25:665-75. 2006
    ..Efficacy trials for all chlorhexidine interventions are needed in low-resource settings in Africa, and the benefit of maternal vaginal cleansing beyond that provided by newborn skin cleansing needs to be determined...
  21. ncbi Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: a community-based, cluster-randomised trial
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
    Lancet 367:910-8. 2006
    ..Omphalitis contributes to neonatal morbidity and mortality in developing countries. Umbilical cord cleansing with antiseptics might reduce infection and mortality risk, but has not been rigorously investigated...
  22. ncbi Daily supplementation with iron plus folic acid, zinc, and their combination is not associated with younger age at first walking unassisted in malnourished preschool children from a deficient population in rural Nepal
    Joanne Katz
    Department of International Health and 6Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 140:1317-21. 2010
    ..5 cm [60.6 d, (95% CI: 28.5, 92.6)]. Risks and benefits of universal iron+folic acid supplementation of infants beyond improved hematologic status deserve further consideration...
  23. ncbi Breast-feeding patterns, time to initiation, and mortality risk among newborns in southern Nepal
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Nutr 138:599-603. 2008
    ..Community-based breast-feeding promotion programs should remain a priority, with renewed emphasis on early initiation in addition to exclusiveness and duration of breast-feeding...
  24. ncbi Maternal vitamin A supplementation and lung function in offspring
    William Checkley
    Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    N Engl J Med 362:1784-94. 2010
    ....
  25. ncbi Risk of mortality subsequent to umbilical cord infection among newborns of southern Nepal: cord infection and mortality
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    Pediatr Infect Dis J 28:17-20. 2009
    ..We compared the risk of mortality between infants with and without signs of umbilical cord infection during a community-based trial of chlorhexidine interventions in southern Nepal...
  26. ncbi Risk factors for maternal night blindness in rural South India
    Joanne Katz
    Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205 2103, USA
    Ophthalmic Epidemiol 16:193-7. 2009
    ..This study aimed to identify risk factors associated with maternal night blindness in rural South India...
  27. ncbi Incidence and risk factors for newborn umbilical cord infections on Pemba Island, Zanzibar, Tanzania
    Luke C Mullany
    Department of International Health, John Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Pediatr Infect Dis J 28:503-9. 2009
    ..We developed simple sign-based definitions of omphalitis and estimated incidence and risk factors for infection over a range of severity among neonates in Pemba, Zanzibar, Tanzania...
  28. ncbi Nasopharyngeal carriage of S. pneumoniae among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Trop Med Int Health 14:1025-33. 2009
    ..To provide epidemiologic data on Streptococcus pneumoniae (Spn) carriage in Nepal...
  29. ncbi Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal
    Parul Christian
    Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room W2041, Baltimore, MD 21205, USA
    JAMA 304:2716-23. 2010
    ..Few studies have examined whether iron and zinc supplementation during gestation, a critical period of central nervous system development, affects children's later functioning...
  30. ncbi Incidence and seasonality of hypothermia among newborns in southern Nepal
    Luke C Mullany
    International Center for Advancing Neonatal Health, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Ste E8646, Baltimore, MD 21205, USA
    Arch Pediatr Adolesc Med 164:71-7. 2010
    ..To quantify incidence, age distribution, and seasonality of neonatal hypothermia among a large population cohort...
  31. ncbi Verbal autopsy methods to ascertain birth asphyxia deaths in a community-based setting in southern Nepal
    Anne C C Lee
    International Center for Advancing Neonatal Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Baltimore, MD 21205, USA
    Pediatrics 121:e1372-80. 2008
    ....
  32. ncbi A randomized controlled trial of the impact of chlorhexidine skin cleansing on bacterial colonization of hospital-born infants in Nepal
    Luke C Mullany
    International Center for Advancing Neonatal Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 27:505-11. 2008
    ..Few data exist on the impact of chlorhexidine cleansing on skin colonization of infants during the first day of life or on the absorption potential of chlorhexidine during newborn skin cleansing...
  33. ncbi Young maternal age and the risk of neonatal mortality in rural Nepal
    Vandana Sharma
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205 2103, USA
    Arch Pediatr Adolesc Med 162:828-35. 2008
    ..To investigate the relationship between adolescent pregnancy and neonatal mortality in a nutritionally deprived population in rural Nepal, and to determine mechanisms through which low maternal age may affect neonatal mortality...
  34. ncbi Role of antimicrobial applications to the umbilical cord in neonates to prevent bacterial colonization and infection: a review of the evidence
    Luke C Mullany
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Room W5009, Baltimore, MD 21205 2103, USA
    Pediatr Infect Dis J 22:996-1002. 2003
    ..quot; The paucity of published reports from developing countries indicates the need to investigate the impact of antimicrobial applications on cord and systemic infections in a community-based, prospective manner...
  35. ncbi Risks and benefits of anticoagulant and antiplatelet medication use before cataract surgery
    Joanne Katz
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205 2103, USA
    Ophthalmology 110:1784-8. 2003
    ..To estimate the risks and benefits associated with continuation of anticoagulants or antiplatelet medication use before cataract surgery...
  36. ncbi Growth indices, anemia, and diet independently predict motor milestone acquisition of infants in south central Nepal
    Emily H Siegel
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    J Nutr 135:2840-4. 2005
    ..We conclude that growth, anemia, and diet are independently associated with delays in the onset of bipedal locomotion among young Nepali children...
  37. ncbi Evaluation of non-specific effects of infant immunizations on early infant mortality in a southern Indian population
    Lawrence H Moulton
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Trop Med Int Health 10:947-55. 2005
    ..The aim of this study was to assess the relationship between receipt of routine childhood immunizations and infant mortality before 6 months of age...
  38. ncbi Experience Corps: design of an intergenerational program to boost social capital and promote the health of an aging society
    Thomas A Glass
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    J Urban Health 81:94-105. 2004
    ..This article explores how the linkage of concepts at multiple levels motivates a potentially cost-effective, feasible, and high-impact program...
  39. ncbi Traditional massage of newborns in Nepal: implications for trials of improved practice
    Luke C Mullany
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Trop Pediatr 51:82-6. 2005
    ....
  40. ncbi Ten-year change in vision-related quality of life in type 1 diabetes: Wisconsin epidemiologic study of diabetic retinopathy
    Flavio E Hirai
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Ophthalmology 118:353-8. 2011
    ..To investigate changes of vision-related quality of life during a 10-year period in a population with type 1 diabetes...
  41. ncbi The utilization of eye care services by persons with glaucoma in rural south India
    Alan L Robin
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Trans Am Ophthalmol Soc 102:47-54; discussion 54-5. 2004
    ..Strategies to improve the uptake of services are required to reduce the burden of blindness due to glaucoma in southern India...
  42. ncbi Effect of daily zinc supplementation on child mortality in southern Nepal: a community-based, cluster randomised, placebo-controlled trial
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2013, USA
    Lancet 370:1230-9. 2007
    ..However, whether routine supplementation would decrease morbidity and mortality in populations with zinc deficiency is unclear. We assessed the effect of daily zinc supplementation on children in southern Nepal...
  43. ncbi Prevalence of decreased visual acuity among preschool-aged children in an American urban population: the Baltimore Pediatric Eye Disease Study, methods, and results
    David S Friedman
    Dana Center for Prevention Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21210, USA
    Ophthalmology 115:1786-95, 1795.e1-4. 2008
    ..To determine the age- and ethnicity-specific prevalence of decreased visual acuity (VA) in white and black preschool-aged children...
  44. ncbi Risk factors for neonatal mortality due to birth asphyxia in southern Nepal: a prospective, community-based cohort study
    Anne C C Lee
    Department of International Health, International Center for Advancing Neonatal Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Baltimore, MD 21205, USA
    Pediatrics 121:e1381-90. 2008
    ..Our goal was to identify antepartum, intrapartum, and infant risk factors for birth asphyxia mortality in a rural, low-resource, population-based cohort in southern Nepal...
  45. ncbi Is there an association between cataract surgery and age-related macular degeneration? Data from three population-based studies
    Ellen E Freeman
    Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 9019, USA
    Am J Ophthalmol 135:849-56. 2003
    ..To determine whether cataract surgery is associated with an increased prevalence of age-related macular degeneration (AMD) in three independent population-based data sets...
  46. ncbi Association between anaemia during pregnancy and blood loss at and after delivery among women with vaginal births in Pemba Island, Zanzibar, Tanzania
    Justine A Kavle
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Health Popul Nutr 26:232-40. 2008
    ....
  47. ncbi The incidence of endophthalmitis after cataract surgery among the U.S. Medicare population increased between 1994 and 2001
    Emily S West
    Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ophthalmology 112:1388-94. 2005
    ..S. population...
  48. ncbi Commentary: Could biomass fuel smoke cause anaemia and stunting in early childhood?
    Jonathan M Samet
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Int J Epidemiol 36:130-1. 2007
  49. ncbi Effect of periodic vitamin A supplementation on mortality and morbidity of human immunodeficiency virus-infected children in Uganda: A controlled clinical trial
    Richard D Semba
    Department of Ophthalmology Johns Hopkins School of Medicine, Baltimore, MD, USA
    Nutrition 21:25-31. 2005
    ..We investigated whether vitamin A supplementation would decrease mortality and morbidity rates in children infected with the human immunodeficiency virus (HIV)...
  50. ncbi A comparison of methods for detecting the eggs of Ascaris, Trichuris, and hookworm in infant stool, and the epidemiology of infection in Zanzibari infants
    David Goodman
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Am J Trop Med Hyg 76:725-31. 2007
    ..4%, while at 10 and 11 months of age the mean prevalence was 43.4%. Village prevalence varied from 3.6% to 43.8%. Infant geohelminth infection can occur at a high prevalence, and what method is best depends on research specifics...
  51. ncbi Effect of instrument precision on estimation of low birth weight prevalence
    Luke C Mullany
    Department of International Health, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Perinatol 25:11-3. 2005
    ..Conclusions concerning programmatic or research intervention impact, or comparisons of rates across populations should consider the effect of instrument precision on estimates of LBW...
  52. ncbi Is the exclusion of children under 24 months from anthelmintic treatment justifiable?
    Antonio Montresor
    Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Trans R Soc Trop Med Hyg 96:197-9. 2002
    ..In light of the potential nutritional benefit achieved by regular deworming in this young age-group, the policy that excludes children aged < 24 months from treatment should be re-considered...
  53. ncbi Prevalence of amblyopia and strabismus in white and African American children aged 6 through 71 months the Baltimore Pediatric Eye Disease Study
    David S Friedman
    Dana Center for Prevention Ophthalmology, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21210, USA
    Ophthalmology 116:2128-34.e1-2. 2009
    ..To determine the age-specific prevalence of strabismus in white and African American children aged 6 through 71 months and of amblyopia in white and African American children aged 30 through 71 months...
  54. ncbi Prevalence of refractive error among preschool children in an urban population: the Baltimore Pediatric Eye Disease Study
    Lydia Giordano
    Dana Center for Prevention Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21210, USA
    Ophthalmology 116:739-46, 746.e1-4. 2009
    ..To determine the age-specific prevalence of refractive errors in white and African-American preschool children...
  55. ncbi Simplified age-weight mortality risk classification for very low birth weight infants in low-resource settings
    Rebecca E Rosenberg
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Pediatr 153:519-24. 2008
    ..To identify a valid neonatal mortality risk prediction score feasible for use in developing countries...
  56. ncbi The prevalence of refractive errors among adults in the United States, Western Europe, and Australia
    John H Kempen
    Johns Hopkins University School of Medicine, 550 N. Broadway, Suite 700, Baltimore, MD 21205, USA
    Arch Ophthalmol 122:495-505. 2004
    ..Projected prevalence rates in 2020 were similar. CONCLUSIONS: Refractive errors affect approximately one third of persons 40 years or older in the United States and Western Europe, and one fifth of Australians in this age group...
  57. ncbi Malaria incidence and prevalence on Pemba island before the onset of the successful control intervention on the Zanzibar archipelago
    Thomas Jaenisch
    Department of Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA
    Malar J 9:32. 2010
    ....
  58. ncbi Age and sex variation in angle findings among normal Chinese subjects: a comparison of UBM, Scheimpflug, and gonioscopic assessment of the anterior chamber angle
    David S Friedman
    Wilmer Eye Institute, Dana Center for Preventive Ophthalmology, Johns Hopkins Medical Institute, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Glaucoma 17:5-10. 2008
    ..Limited data are published on the ultrasound biomicroscope (UBM) findings of the anterior chamber angle. This work provides a population-based assessment of angle findings and compares 3 modalities for assessing angle dimensions...
  59. ncbi A social model for health promotion for an aging population: initial evidence on the Experience Corps model
    Linda P Fried
    Medicine, Epidemiology and Health Policy, Division of Geriatric Medicine and Gerontology, Johns Hopkins Medical Institutions, JHU School of Medicine, 2024 East Monument Street, Baltimore, MD 21205, USA
    J Urban Health 81:64-78. 2004
    ..In this pilot trial, physical, cognitive, and social activity increased, suggesting the potential for the Experience Corps to improve health for an aging population and simultaneously improve educational outcomes for children...
  60. ncbi The incidence of microbial keratitis among wearers of a 30-day silicone hydrogel extended-wear contact lens
    Oliver D Schein
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ophthalmology 112:2172-9. 2005
    ..Duluth, GA), recently approved for up to 30 days of continuous wear...
  61. ncbi Safety of neonatal skin cleansing in rural Nepal
    Luke C Mullany
    Department of International Health and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Indian Pediatr 43:117-24. 2006
    ..This procedure is safe and appropriate precautions can be taken to deliver safe skin antisepsis with chlorhexidine to infants in the community...
  62. ncbi Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool children
    Sarah E Cusick
    Center for Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Clin Nutr 82:406-12. 2005
    ..Impaired erythropoietin production is one possible mechanism. Plasmodium falciparum malaria has been found to blunt erythropoietin production, whereas vitamin A stimulates erythropoietin production in vitro...
  63. ncbi Lack of concordance between fixation preference and HOTV optotype visual acuity in preschool children: the Baltimore Pediatric Eye Disease Study
    David S Friedman
    Dana Center for Prevention Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21210, USA
    Ophthalmology 115:1796-9. 2008
    ..To compare the results of fixation preference testing and standardized visual acuity testing in white and black children aged 30 through 71 months...
  64. ncbi Estimating the rate of progressive visual field damage in those with open-angle glaucoma, from cross-sectional data
    Aimee Teo Broman
    Dana Center for Preventive Ophthalmology and the Glaucoma Service, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Invest Ophthalmol Vis Sci 49:66-76. 2008
    ..To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies...
  65. ncbi Lens opacities in a rural population of southern India: the Aravind Comprehensive Eye Study
    Praveen K Nirmalan
    Aravind Medical Research Foundation, Aravind Eye Care System, Madurai, Tamilnadu, India
    Invest Ophthalmol Vis Sci 44:4639-43. 2003
    ....
  66. ncbi Pseudoexfoliation in a rural population of southern India: the Aravind Comprehensive Eye Survey
    R Krishnadas
    Aravind Eye Care System and Lions-Aravind Institute for Community Ophthalmology, Madurai, Tamilnadu, India
    Am J Ophthalmol 135:830-7. 2003
    ....
  67. ncbi Performance of the Haemoglobin Colour Scale in diagnosing severe and very severe anaemia
    Antonio Montresor
    World Health Organization, Geneva, Switzerland
    Trop Med Int Health 8:619-24. 2003
    ....
  68. ncbi Glaucoma in a rural population of southern India: the Aravind comprehensive eye survey
    R Ramakrishnan
    Aravind Eye Care System, Madurai, Tamil Nadu, India
    Ophthalmology 110:1484-90. 2003
    ..One fifth of those with POAG had blindness in one or both eyes from glaucoma. Early detection of glaucoma in this population will reduce the burden of blindness in India...
  69. ncbi Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool children
    Rebecca J Stoltzfus
    Division of Nutritional Sciences, Cornell University, Ithaca, NY UNICEF, Zanzibar, Tanzania
    J Nutr 134:348-56. 2004
    ..We hypothesize that incident helminth infections may stimulate inflammatory immune responses in young children, with deleterious effects on protein metabolism and erythropoiesis...
  70. ncbi Prevalence and causes of low vision and blindness in an urban malay population: the Singapore Malay Eye Study
    Tien Yin Wong
    Centre for Eye Research Australia, The University of Melbourne, 32 Gisborne St, Melbourne 3002, Victoria, Australia
    Arch Ophthalmol 126:1091-9. 2008
    ..To describe the prevalence and causes of low vision and blindness in a Malay population...
  71. ncbi Blindness and vision impairment in a rural south Indian population: the Aravind Comprehensive Eye Survey
    R D Thulasiraj
    Aravind Eye Care System and Lions-Aravind Institute for Community Ophthalmology, Madurai, Tamil Nadu, India
    Ophthalmology 110:1491-8. 2003
    ..Cataracts and refractive errors remain the major reversible causes for the burden of vision impairment in this rural population...
  72. ncbi Combined iron and folic acid supplementation with or without zinc reduces time to walking unassisted among Zanzibari infants 5- to 11-mo old
    Deanna K Olney
    U.S. Department of Agriculture, ARS-Western Human Nutrition Research Center, Davis, CA, USA
    J Nutr 136:2427-34. 2006
    ..There were no significant treatment effects on changes in HAZ or WAZ. The effects of treatment on time to walking may have been mediated by improvements in iron status or hemoglobin, but were not mediated through improvements in growth...
  73. ncbi Iron deficiency and physical growth predict attainment of walking but not crawling in poorly nourished Zanzibari infants
    Patricia K Kariger
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    J Nutr 135:814-9. 2005
    ..In this sample of poorly nourished infants, growth and anemia-iron status are significant predictors of walking, but not crawling...
  74. ncbi Maternal reports of sleep in 6-18 month-old infants from Nepal and Zanzibar: association with iron deficiency anemia and stunting
    Katarzyna Kordas
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, United States
    Early Hum Dev 84:389-98. 2008
    ..They may also be fatigued more often, suggesting their sleep may be affected. It is unclear whether fatigue in these infants is due to poor nighttime sleep or if it is compensated for with frequent naps or longer sleep...
  75. ncbi Young Zanzibari children with iron deficiency, iron deficiency anemia, stunting, or malaria have lower motor activity scores and spend less time in locomotion
    Deanna K Olney
    Program in International and Community Nutrition, University of California, Davis, CA 95616, USA
    J Nutr 137:2756-62. 2007
    ....
  76. ncbi Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India
    Lakshmi Rahmathullah
    Aravind Centre for Women, Children and Community Health, Madurai, Tamil Nadu, India
    BMJ 327:254. 2003
    ..CONCLUSION: Supplementing newborn infants with vitamin A can significantly reduce early infant mortality...
  77. ncbi Vitamin A supplements in newborns and child survival
    James M Tielsch
    BMJ 336:1385-6. 2008
  78. ncbi Ocular trauma in a rural south Indian population: the Aravind Comprehensive Eye Survey
    Praveen K Nirmalan
    Aravind Medical Research Foundation, Aravind Eye Care System, Madurai, India
    Ophthalmology 111:1778-81. 2004
    ..Simple measures such as education regarding the use of protective eyewear could possibly significantly decrease this preventable cause of visual disability...
  79. ncbi Prevalence of vitreoretinal disorders in a rural population of southern India: the Aravind Comprehensive Eye Study
    Praveen K Nirmalan
    Aravind Medical Research Foundation, Aravind Eye Care System, Madurai, India
    Arch Ophthalmol 122:581-6. 2004
    ..4%-0.8%), respectively. CONCLUSIONS: Vitreoretinal diseases appear to be a major public health problem in India. Emphasis on diabetic screening, diabetic therapy, and appropriate laser therapy of diabetic retinopathy must be explored...
  80. ncbi Female reproductive factors and eye disease in a rural South Indian population: the Aravind Comprehensive Eye Survey
    Praveen K Nirmalan
    Aravind Medical Research Foundation, Aravind Eye Care System, Madurai, India
    Invest Ophthalmol Vis Sci 45:4273-6. 2004
    ..CONCLUSIONS: Female reproductive factors do not appear to influence age-related cataract, open-angle glaucoma, macular degeneration or myopia significantly in rural south India...
  81. ncbi Factors influencing career choices among graduating ophthalmology residents
    Steven J Gedde
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, USA
    Ophthalmology 112:1247-54. 2005
    ..To identify factors influencing graduating ophthalmology residents to pursue subspecialty training or a career in comprehensive ophthalmology...
  82. ncbi A self-administered health questionnaire for the preoperative risk stratification of patients undergoing cataract surgery
    Sherman W Reeves
    Duke University Eye Center, Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA
    Am J Ophthalmol 135:599-606. 2003
    ..CONCLUSIONS: The self-administered questionnaire showed a high degree of specificity for 12 common comorbid conditions in cataract patients. A questionnaire such as this may be useful in preoperative risk stratification...
  83. ncbi Geophagia is not associated with Trichuris or hookworm transmission in Zanzibar, Tanzania
    Sera L Young
    Cornell University, Division of Nutritional Sciences, International Nutrition, Savage Hall, Ithaca, NY 14853, USA
    Trans R Soc Trop Med Hyg 101:766-72. 2007
    ....
  84. ncbi Risk factors for corneal infiltrates with continuous wear of contact lenses
    Robin L Chalmers
    Optom Vis Sci 84:573-9. 2007
    ..To describe the factors associated with symptomatic corneal infiltrates in a postmarket surveillance study of continuous wear contact lenses...
  85. ncbi Relationship between vision impairment and eye disease to vision-specific quality of life and function in rural India: the Aravind Comprehensive Eye Survey
    Praveen K Nirmalan
    Aravind Medical Research Foundation, Aravind Eye Care System, Madurai, India
    Invest Ophthalmol Vis Sci 46:2308-12. 2005
    ..Subjects with glaucoma and age-related cataract had an associated decrease in quality of life and vision function, independent of presenting visual acuity in the better eye...
  86. ncbi Blindness and visual impairment: a public health issue for the future as well as today
    Frederick L Ferris
    Arch Ophthalmol 122:451-2. 2004

Research Grants16

  1. Cookstove Replacement for Prevention of ARI and Low Birthweight in Nepal
    James M Tielsch; Fiscal Year: 2010
    ..If the replacement of these stoves works to reduce respiratory infections and low birthweight, significant number of children's lives can be saved at very low cost. ..
  2. BALTIMORE PEDIATRIC EYE SURVEY
    James Tielsch; Fiscal Year: 2007
    ..The analysis will focus on estimating the age and race-specific prevalence of ocular disorders in this group and on assessing the association of selected risk factors with the prevalence of these disorders. ..
  3. BALTIMORE PEDIATRIC EYE SURVEY
    James Tielsch; Fiscal Year: 2007
    ..The analysis will focus on estimating the age and race-specific prevalence of ocular disorders in this group and on assessing the association of selected risk factors with the prevalence of these disorders. ..
  4. Newborn Antiseptic Washing and Neonatal Mortality-Nepal
    James Tielsch; Fiscal Year: 2005
    ..The umbilical cord infection trial will require only one year of recruitment to obtain adequate numbers to detect a 20% in infection rates in the treatment groups. ..
  5. ZINC SUPPLEMENTATION IMPACT ON CHILD MORTALITY--NEPAL
    James Tielsch; Fiscal Year: 2003
    ..The analysis will focus on comparison of rates of mortality and morbidity between treatment groups with additional analyses of subgroups to look for interaction by age, gender or baseline nutritional status. ..
  6. Cookstove Replacement for Prevention of ARI and Low Birthweight in Nepal
    James Tielsch; Fiscal Year: 2009
    ..If the replacement of these stoves works to reduce respiratory infections and low birthweight, significant number of children's lives can be saved at very low cost. ..