Janis M Taube

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
    Janis M Taube
    Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Sci Transl Med 4:127ra37. 2012
  2. ncbi request reprint Langerhans cell density and high-grade vulvar intraepithelial neoplasia in women with human immunodeficiency virus infection
    Janis M Taube
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Cutan Pathol 34:565-70. 2007
  3. doi request reprint Human papillomavirus prevalence and cytopathology correlation in young Ugandan women using a low-cost liquid-based Pap preparation
    Janis M Taube
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Diagn Cytopathol 38:555-63. 2010
  4. doi request reprint Differentiated (simplex) vulvar intraepithelial neoplasia: a case report and review of the literature
    Janis M Taube
    Departments of Dermatology and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Dermatopathol 33:e27-30. 2011
  5. pmc Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody
    Evan J Lipson
    Department of Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA
    Clin Cancer Res 19:462-8. 2013
  6. pmc Detection of transcriptionally active high-risk HPV in patients with head and neck squamous cell carcinoma as visualized by a novel E6/E7 mRNA in situ hybridization method
    Justin A Bishop
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 36:1874-82. 2012
  7. pmc Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    Suzanne L Topalian
    Department of Surgery, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA
    N Engl J Med 366:2443-54. 2012
  8. pmc Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
    Sofia Lyford-Pike
    Department of Otolaryngology Head and Neck Surgery, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
    Cancer Res 73:1733-41. 2013
  9. doi request reprint Benign nodal nevi frequently harbor the activating V600E BRAF mutation
    Janis M Taube
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Surg Pathol 33:568-71. 2009
  10. doi request reprint Inverse relationship between human papillomavirus-16 infection and disruptive p53 gene mutations in squamous cell carcinoma of the head and neck
    William H Westra
    Department of Pathology and Otolaryngology, Head and Neck Surgery Division of Head and Neck Cancer Research, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Clin Cancer Res 14:366-9. 2008

Collaborators

Detail Information

Publications21

  1. pmc Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
    Janis M Taube
    Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Sci Transl Med 4:127ra37. 2012
    ..These observations suggest that therapies that block this pathway may benefit patients with B7-H1(+) tumors...
  2. ncbi request reprint Langerhans cell density and high-grade vulvar intraepithelial neoplasia in women with human immunodeficiency virus infection
    Janis M Taube
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Cutan Pathol 34:565-70. 2007
    ..The objective of this study was to compare the S100+ LC density in high-grade vulvar intraepithelial neoplasia (VIN) in HIV-positive and HIV-negative women...
  3. doi request reprint Human papillomavirus prevalence and cytopathology correlation in young Ugandan women using a low-cost liquid-based Pap preparation
    Janis M Taube
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Diagn Cytopathol 38:555-63. 2010
    ..Notably, the manual low-cost liquid-based Pap preparation is practical in this setting and offers an alternate method for local studies of HPV vaccine efficacy...
  4. doi request reprint Differentiated (simplex) vulvar intraepithelial neoplasia: a case report and review of the literature
    Janis M Taube
    Departments of Dermatology and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Dermatopathol 33:e27-30. 2011
    ....
  5. pmc Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody
    Evan J Lipson
    Department of Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA
    Clin Cancer Res 19:462-8. 2013
    ..Here, we provide long-term follow-up on three patients from that trial who sustained objective tumor regressions off therapy, and test the hypothesis that reinduction therapy for late tumor recurrence can be effective...
  6. pmc Detection of transcriptionally active high-risk HPV in patients with head and neck squamous cell carcinoma as visualized by a novel E6/E7 mRNA in situ hybridization method
    Justin A Bishop
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 36:1874-82. 2012
    ....
  7. pmc Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    Suzanne L Topalian
    Department of Surgery, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA
    N Engl J Med 366:2443-54. 2012
    ..Blockade of programmed death 1 (PD-1), an inhibitory receptor expressed by T cells, can overcome immune resistance. We assessed the antitumor activity and safety of BMS-936558, an antibody that specifically blocks PD-1...
  8. pmc Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
    Sofia Lyford-Pike
    Department of Otolaryngology Head and Neck Surgery, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
    Cancer Res 73:1733-41. 2013
    ....
  9. doi request reprint Benign nodal nevi frequently harbor the activating V600E BRAF mutation
    Janis M Taube
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Surg Pathol 33:568-71. 2009
    ..Indeed, these nodal nevi, like melanoma, frequently harbor activating mutations of the BRAF oncogene underscoring the potentially confounding impact of these inclusions on melanoma detection...
  10. doi request reprint Inverse relationship between human papillomavirus-16 infection and disruptive p53 gene mutations in squamous cell carcinoma of the head and neck
    William H Westra
    Department of Pathology and Otolaryngology, Head and Neck Surgery Division of Head and Neck Cancer Research, The Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Clin Cancer Res 14:366-9. 2008
    ..The purpose of this study was to discern whether HNSCCs differ in the type of p53 mutations as a function of HPV16 status...
  11. doi request reprint Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 44:959-65. 2013
    ..Sox10 expression in the basal-like, unclassified triple-negative, and metaplastic carcinomas types supports the concept that these neoplasms show myoepithelial differentiation...
  12. doi request reprint Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses
    Jeonghyun Shin
    Department of Dermatology, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Am Acad Dermatol 67:717-26. 2012
    ..Sox10 is a transcription factor associated with neural crest development. Its expression has been reported in melanocytes and peripheral nerve sheath cells and their associated tumors...
  13. doi request reprint Quantitative comparison of MiTF, Melan-A, HMB-45 and Mel-5 in solar lentigines and melanoma in situ
    Jinah Kim
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    J Cutan Pathol 38:775-9. 2011
    ..Therefore, dermatopathologists routinely use immunostains to help differentiate melanocytes from surrounding keratinocytes...
  14. doi request reprint Merkel cell carcinoma: update and review
    Timothy S Wang
    Division of Cutaneous Surgery and Oncology, Department of Dermatology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Semin Cutan Med Surg 30:48-56. 2011
    ..Recent effort has broadened our breadth of knowledge regarding MCC and developed instruments to improve data collection and future study. This article provides an update on current thinking about the Merkel cell and MCC...
  15. doi request reprint Characterization of human mesenchymal stem cell-engineered cartilage: analysis of its ultrastructure, cell density and chondrocyte phenotype compared to native adult and fetal cartilage
    Alexander T Hillel
    Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA
    Cells Tissues Organs 191:12-20. 2010
    ....
  16. ncbi request reprint Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer
    Suhail K Mithani
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 0910, USA
    Clin Cancer Res 13:4331-5. 2007
    ..To determine the timing of mitochondrial mutations in the progression of head and neck squamous cell carcinoma...
  17. pmc Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes
    Christopher M Heaphy
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Am J Pathol 179:1608-15. 2011
    ..These findings may have therapeutic consequences, because ALT-positive cancers are predicted to be resistant to anti-telomerase therapies...
  18. doi request reprint Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates
    Julie R Brahmer
    Johns Hopkins University School of Medicine, and the Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
    J Clin Oncol 28:3167-75. 2010
    ..This phase I study sought to determine the safety and tolerability of anti-PD-1 blockade in patients with treatment-refractory solid tumors and to preliminarily assess antitumor activity, pharmacodynamics, and immunologic correlates...
  19. doi request reprint Photoactivated composite biomaterial for soft tissue restoration in rodents and in humans
    Alexander T Hillel
    Department of Otolaryngology, Johns Hopkins University, Baltimore, MD 21287, USA
    Sci Transl Med 3:93ra67. 2011
    ..Pilot clinical testing in human patients confirmed the feasibility of the transdermal photocrosslinking approach for implantation in abdomen soft tissue, although an inflammatory response was observed surrounding some of the materials...
  20. ncbi request reprint Multifocal ischemic necroses of varying age (MINOVA): A distinctive form of atherosclerotic heart disease
    Janis M Taube
    Department of Pathology, The Johns Hopkins Medical Institutions, Room 400, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Pathol Res Pract 204:113-20. 2008
    ..Review of patient histories showed that the clinical suspicion for the degree of ischemic heart disease did not correlate well with the severity of the pathological findings...
  21. pmc Combined use of PCR-based TCRG and TCRB clonality tests on paraffin-embedded skin tissue in the differential diagnosis of mycosis fungoides and inflammatory dermatoses
    Bing Zhang
    Department of Pathology, L235, Stanford University Medical Center, Stanford, CA 94305, USA
    J Mol Diagn 12:320-7. 2010
    ..Combined use of the two tests in patients with intermediate pretest probabilities as proposed in the algorithm could improve test utility...