Research Topics
| Harikrishna TandriSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Normal reference values for the adult right ventricle by magnetic resonance imagingHarikrishna Tandri
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Cardiol 98:1660-4. 2006..These values will be useful to differentiate RV health from diseases that result in abnormal RV structure and function...
Prolonged RV endocardial activation duration: a novel marker of arrhythmogenic right ventricular dysplasia/cardiomyopathyHarikrishna Tandri
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Heart Rhythm 6:769-75. 2009..Parietal block, defined as intra right ventricular (RV) conduction slowing, is a major diagnostic criterion for arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)...
Determinants of gradient field-induced current in a pacemaker lead system in a magnetic resonance imaging environmentHarikrishna Tandri
Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Heart Rhythm 5:462-8. 2008..The determinants of low-frequency-induced current by magnetic resonance imaging (MRI) gradient fields in a pacemaker lead system are largely unknown...- Unusual presentation of cardiac sarcoidosisHarikrishna Tandri
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Congest Heart Fail 13:116-8. 2007..This case illustrates the importance of complete testing, including invasive studies such as endomyocardial biopsy, in patients presenting with life-threatening ventricular arrhythmias to establish a correct diagnosis... - Regional differences in systolic and diastolic function in arrhythmogenic right ventricular dysplasia/cardiomyopathy using magnetic resonance imagingChandra Bomma
Division of Cardiology (Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Am J Cardiol 95:1507-11. 2005..In this study, we report results of quantitative evaluation of biventricular global and regional function using peak ejection rate and peak filling rate as measures of systolic and diastolic function, respectively (volumetric method)... - Comparison of novel echocardiographic parameters of right ventricular function with ejection fraction by cardiac magnetic resonanceJianwen Wang
Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
J Am Soc Echocardiogr 20:1058-64. 2007..We sought to determine which echocardiographic variable or variables best correlated with RV ejection fraction (RVEF) by cardiac magnetic resonance... - Prevalence of left ventricular regional dysfunction in arrhythmogenic right ventricular dysplasia: a tagged MRI studyAditya Jain
Department of Radiology, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Circ Cardiovasc Imaging 3:290-7. 2010..Regional left ventricular (LV) function has not been systematically studied in ARVD... - Reader- and instrument-dependent variability in the electrocardiographic assessment of arrhythmogenic right ventricular dysplasia/cardiomyopathyRahul Jain
Department of Medicine Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
J Cardiovasc Electrophysiol 22:561-8. 2011..This study was aimed at examining the variability in the ECG interpretation resulting from the same reader, different readers, and using different ECG-resolutions... - Magnetic resonance imaging of arrhythmogenic right ventricular dysplasia: sensitivity, specificity, and observer variability of fat detection versus functional analysis of the right ventricleHarikrishna Tandri
Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
J Am Coll Cardiol 48:2277-84. 2006..Among the qualitative parameters, fat infiltration is less reproducible and lacks specificity compared with RV kinetic abnormalities... - Feasibility and variability of three dimensional echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathyKalpana R Prakasa
Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
Am J Cardiol 97:703-9. 2006..In conclusion, 3DE measurements of RV volumes and ejection fractions closely correlate with CMR values and may be useful in the follow-up of patients with ARVD/C... - Arrhythmogenic right ventricular dysplasia: a United States experienceDarshan Dalal
Division of Cardiology, The Johns Hopins University School of Medicine, Baltimore, MD, USA
Circulation 112:3823-32. 2005..Diagnosis is often delayed. Once diagnosed and treated with an ICD, mortality is low. There is a wide variation in presentation and course of ARVD patients, which can likely be explained by the genetic heterogeneity of the disease... - Changes of pulmonary vein orifice size and location throughout the cardiac cycle: dynamic analysis using magnetic resonance cine imagingLars Lickfett
Division of Cardiology, The John Hopkins University, Baltimore, Maryland, USA
J Cardiovasc Electrophysiol 16:582-8. 2005..The aim of the current study was therefore to analyze changes of PV orifice size and location throughout the cardiac cycle using cine magnetic resonance imaging (MRI)... - Outcomes of catheter ablation of ventricular tachycardia in arrhythmogenic right ventricular dysplasia/cardiomyopathyBinu Philips
Division of Cardiology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Circ Arrhythm Electrophysiol 5:499-505. 2012..The overall objective of the present study was to assess the efficacy of radiofrequency catheter ablation (RFA) of VT in ARVD/C, with particular focus on newer ablation strategies, including epicardial catheter ablation... - Findings on magnetic resonance imaging of idiopathic right ventricular outflow tachycardiaHarikrishna Tandri
Division of Cardiology, Department of Radiology, The Johns Hopkins University, Baltimore, Maryland, USA
Am J Cardiol 94:1441-5. 2004..There were no differences in incidence of qualitative MRI findings in patients compared with controls. These findings do not favor an association between anatomic abnormalities and arrhythmia in these patients... - Misdiagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathyChandra Bomma
Department of Cardiology Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Cardiovasc Electrophysiol 15:300-6. 2004..Diagnosis of ARVD/C cannot rely solely upon qualitative features on MRI... - Filtered QRS duration on signal-averaged electrocardiography predicts inducibility of ventricular tachycardia in arrhythmogenic right ventricle dysplasiaKhurram Nasir
Department of Cardiology, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Pacing Clin Electrophysiol 26:1955-60. 2003..Filtered QRS duration on SAECG is predictive of electrophysiological study outcome in ARVD. Further studies will be needed to determine if SAECG results can predict the development of ventricular arrhythmias during follow-up... - Evolving role of multidetector computed tomography in evaluation of arrhythmogenic right ventricular dysplasia/cardiomyopathyChandra Bomma
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Cardiol 100:99-105. 2007..Limitations include implantable cardioverter-defibrillators and motion artifacts, along with well-known radiation and contrast-induced reaction... - Morphologic variants of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy a genetics-magnetic resonance imaging correlation studyDarshan Dalal
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Am Coll Cardiol 53:1289-99. 2009.... - Implantable cardioverter-defibrillators in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathyAriel Roguin
Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA
J Am Coll Cardiol 43:1843-52. 2004..23 to 101.24, p = 0.031). CONCLUSIONS: Patients with ARVD/C have a high arrhythmia rate requiring appropriate ICD interventions. The ICD therapy appears to be well tolerated and important in the management of patients with ARVD/C... - Noninvasive detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy using delayed-enhancement magnetic resonance imagingHarikrishna Tandri
Division of Cardiology, The Johns Hopkins University, Baltimore, MD 21287, USA
J Am Coll Cardiol 45:98-103. 2005.... - Evaluation and course of an unusual case of arrhythmogenic right ventricular dysplasiaJan Fritz
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Int J Cardiovasc Imaging 22:269-73. 2006..In this report, we describe accurate evaluation by MR imaging confirmed by histopathologic findings as well as imaging progression of this unusual case of arrhythmogenic right ventricular dysplasia... - Electrocardiographic findings over time in arrhythmogenic right ventricular dysplasia/cardiomyopathyJonathan P Piccini
Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Am J Cardiol 96:122-6. 2005..Over a median of 43 months, 89% of the patients had evidence of progression, with S-wave prolongation being the most prevalent marker of ECG progression... - Arrhythmogenic right ventricular dysplasia: ex vivo and in vivo fat detection with black-blood MR imagingErnesto Castillo
Russell H. Morgan Dept of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, MRI-143 Nelson Basement, Baltimore, MD 21287, USA
Radiology 232:38-48. 2004..When fast SE imaging is applied in vivo, however, breath-holding constraints limit the spatial resolution for RV fat detection... - Long-term efficacy of catheter ablation of ventricular tachycardia in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathyDarshan Dalal
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Am Coll Cardiol 50:432-40. 2007..Particular focus was placed on defining the single-procedure efficacy over long-term follow-up... - Utility of tissue Doppler and strain echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathyKalpana R Prakasa
Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
Am J Cardiol 100:507-12. 2007..Peak RV systolic velocity <7.5 cm/s and peak RV strain <18% best identify patients with ARVD... - Prevalence and pathophysiologic attributes of ventricular dyssynchrony in arrhythmogenic right ventricular dysplasia/cardiomyopathyLaurens F Tops
Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Am Coll Cardiol 54:445-51. 2009..This study sought to investigate the prevalence and mechanisms underlying right ventricular (RV) dyssynchrony in arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) using tissue Doppler echocardiography (TDE)... - Axial black blood turbo spin echo imaging of the right ventricleSeth J Berkowitz
The Johns Hopkins University School of Medicine, Department of Radiology and Radiological Sciences, Baltimore, Maryland 21287, USA
Magn Reson Med 61:307-14. 2009..Black blood TSE imaging of the RV free wall is highly sensitive to cardiac motion. Image quality can be improved by choosing TIs concordant with the rest period of the patient's RV that may occur at mid-diastole or end-systole... - Right ventricle shape and contraction patterns and relation to magnetic resonance imaging findingsJan Fritz
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Comput Assist Tomogr 29:725-33. 2005..CONCLUSIONS: With increasing subtended angles, variation of the normal RV appearance is substantially higher on axial views compared with HLA views... - Electrocardiographic features of arrhythmogenic right ventricular dysplasia/cardiomyopathy according to disease severity: a need to broaden diagnostic criteriaKhurram Nasir
Department of Medicine, The Johns Hopkins University, Baltimore, MD, USA
Circulation 110:1527-34. 2004..This feature also best distinguished ARVD/C (diffuse and localized) from RVOT. CONCLUSIONS: A prolonged S-wave upstroke in V1 through V3 is the most frequent ECG finding in ARVD/C and should be considered as a diagnostic ECG marker... - Magnetic resonance imaging findings in patients meeting task force criteria for arrhythmogenic right ventricular dysplasiaHarikrishna Tandri
Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
J Cardiovasc Electrophysiol 14:476-82. 2003..Trabecular disarray is seen more frequently than wall thinning and aneurysms. RV dimensions and volumes differ significantly in ARVD compared to controls, indicating a role for quantitative evaluation in the diagnosis of ARVD... - Utility of a combined signal-averaged electrocardiogram and QT dispersion algorithm in identifying arrhythmogenic right ventricular dysplasia in patients with tachycardia of right ventricular originKhurram Nasir
Department of Cardiology, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Am J Cardiol 92:105-9. 2003 - Role of magnetic resonance imaging in arrhythmogenic right ventricular dysplasia: insights from the North American arrhythmogenic right ventricular dysplasia (ARVD/C) studyHarikrishna Tandri
Department of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am Heart J 155:147-53. 2008..The aim of our study was to define the prevalence, sensitivity, and specificity of quantitative MR imaging findings in the probands of multidisciplinary study of right ventricular dysplasia... - Shared desmosome gene findings in early and late onset arrhythmogenic right ventricular dysplasia/cardiomyopathyBoon Yew Tan
Department of Medicine Cardiology, Johns Hopkins University School of Medicine, Rutland Avenue, Baltimore, MD 21205, USA
J Cardiovasc Transl Res 3:663-73. 2010..027). The presence of these variants did not associate with the age of onset of ARVD/C or ventricular tachycardia. These findings highlight the complex interplay of environmental and genetic factors contributing to this condition... - Utility of SAECG in arrhythmogenic right ventricle dysplasiaKhurram Nasir
Department of Cardiology, The Johns Hopkins University, Baltimore, MD 21087, USA
Ann Noninvasive Electrocardiol 8:112-20. 2003..The ongoing multidisciplinary study of right ventricular dysplasia will hopefully answer some of these questions... - Predictors of high defibrillation threshold in the modern eraEdward F Lin
Johns Hopkins University, Baltimore, Maryland, USA
Pacing Clin Electrophysiol 36:231-7. 2013..Identification of the predictors of elevated DFT may allow selective application of DFT testing. However, the clinical characteristics of patients with high DFT in the modern era have not been well-defined... - High prevalence of catecholamine-facilitated focal ventricular tachycardia in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathyBinu Philips
Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Circ Arrhythm Electrophysiol 6:160-6. 2013..We hypothesized that VT in arrhythmogenic right ventricular dysplasia/cardiomyopathy shows a high degree of association with the PVC at baseline... - Obesity and right ventricular structure and function: the MESA-Right Ventricle StudyHarjit Chahal
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Chest 141:388-95. 2012..The relationship between obesity and right ventricular (RV) morphology is not well studied. We aimed to determine the association between obesity and RV structure and function in a large multiethnic population-based cohort... - Relation of cardiovascular risk factors to right ventricular structure and function as determined by magnetic resonance imaging (results from the multi-ethnic study of atherosclerosis)Harjit Chahal
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Cardiol 106:110-6. 2010..Cardiovascular risk factors, especially blood pressure and high-density lipoprotein cholesterol, are associated with subclinical changes in the RV mass and volume... - Physical activity and right ventricular structure and function. The MESA-Right Ventricle StudyCarrie P Aaron
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Respir Crit Care Med 183:396-404. 2011..However, the effect of physical activity on the RV in an older community-based population is unknown. Objectives: We studied the association between levels of physical activity in adults and RV mass and volumes... - Myocardial structural associations with local electrograms: a study of postinfarct ventricular tachycardia pathophysiology and magnetic resonance-based noninvasive mappingTakeshi Sasaki
Department of Medicine Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Circ Arrhythm Electrophysiol 5:1081-90. 2012..We aimed to quantify these associations to gain insights regarding LGE-CMR image characteristics of tissues and critical sites that support postinfarct ventricular tachycardia (VT)... - The apparent inversion time for optimal delayed enhancement magnetic resonance imaging differs between the right and left ventriclesMilind Y Desai
Division of Cardiology, Johns Hopkins University, Baltimore, Maryland 21287, USA
J Cardiovasc Magn Reson 7:475-9. 2005..Alternatively, increased blood pool signal (within Thebesian veins or arterioluminal communications) in RV compared to LV leads to altered TI times due to similar partial volume effects... - Incidence and predictors of implantable cardioverter-defibrillator therapy in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy undergoing implantable cardioverter-defibrillator implantation for primary preventionAditya Bhonsale
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Am Coll Cardiol 58:1485-96. 2011.... - Continuation of warfarin during pacemaker or implantable cardioverter-defibrillator implantation: a randomized clinical trialAlan Cheng
Section of Cardiac Electrophysiology, Division of Cardiology, Johns Hopkins Medical Institutes, Baltimore, Maryland, USA
Heart Rhythm 8:536-40. 2011..Prior studies demonstrate that continuation of warfarin may be safer when compared with strategies requiring interruption and/or heparin bridging. Limited data from randomized trials exist... - Clinical course and long-term follow-up of patients receiving implantable cardioverter-defibrillatorsHarikrishna Tandri
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Heart Rhythm 3:762-8. 2006..A measurable arrhythmic risk even after prolonged shock-free intervals indicates the need for continued ICD therapy in all patients with appropriate ICD indications... - Effects of surgical and endoscopic electrocautery on modern-day permanent pacemaker and implantable cardioverter-defibrillator systemsAlan Cheng
Section for Cardiac Electrophysiology, Division of Cardiovascular Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Pacing Clin Electrophysiol 31:344-50. 2008..The ability of newer devices to withstand system malfunction or failure during surgery/endoscopy remains unknown... - Magnetic resonance and computed tomography imaging of arrhythmogenic right ventricular dysplasiaHarikrishna Tandri
Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland 21287, USA
J Magn Reson Imaging 19:848-58. 2004..This article discusses the current status and role of MRI and CT imaging in the diagnosis of ARVD... - Diagnostic and prognostic utility of electrocardiography for left ventricular hypertrophy defined by magnetic resonance imaging in relationship to ethnicity: the Multi-Ethnic Study of Atherosclerosis (MESA)Aditya Jain
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am Heart J 159:652-8. 2010..Ethnicity is believed to affect electrocardiographic (ECG) performance. We evaluated the diagnostic and prognostic performance of ECG for left ventricular hypertrophy (LVH) as defined by MRI in relationship to ethnicity... - Role of cardiovascular magnetic resonance imaging in arrhythmogenic right ventricular dysplasiaAditya Jain
Russell H, Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, USA
J Cardiovasc Magn Reson 10:32. 2008..This article reviews the genetics of ARVD, current status and role of CMR in the diagnosis of ARVD and LV involvement in ARVD... - Characterization of a new pulmonary vein variant using magnetic resonance angiography: incidence, imaging, and interventional implications of the "right top pulmonary vein"Lars Lickfett
Division of Cardiology, The Johns Hopkins Hospital, Baltimore, Maryland 21287-0409, USA
J Cardiovasc Electrophysiol 15:538-43. 2004..quot; It is important to be aware of this anatomic pattern to avoid inadvertent catheter intubation, which can result in misleading mapping results and PV stenosis... - Reversible cardiac conduction block and defibrillation with high-frequency electric fieldHarikrishna Tandri
Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Sci Transl Med 3:102ra96. 2011..HFAC may be an effective and potentially safer alternative to direct current application, currently used to treat ventricular fibrillation... - MRI of arrhythmogenic right ventricular cardiomyopathy/dysplasiaHarikrishna Tandri
Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
J Cardiovasc Magn Reson 6:557-63. 2004..It has the unique ability to provide tissue characterization in addition to providing functional information. This article presents the basic techniques for the evaluation of right ventricular cardiomyopathy... - Magnetic resonance imaging of arrhythmogenic right ventricular dysplasiaHarikrishna Tandri
Department of Cardiology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Cardiovasc Electrophysiol 13:1180. 2002 - Controversial role of magnetic resonance imaging in the diagnosis of arrhythmogenic right ventricular dysplasiaHarikrishna Tandri
Am J Cardiol 92:649. 2003