Research Topics
Species | Kellie L TamashiroSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Cloned mice have an obese phenotype not transmitted to their offspringKellie L K Tamashiro
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Nat Med 8:262-7. 2002..We also show that the obese phenotype is not transmitted to offspring generated by mating male and female cloned mice...- Phenotype of cloned mice: development, behavior, and physiologyKellie L K Tamashiro
Department of Psychiatry and Neuroscience Program, University of Cincinnati, Cincinnati, Ohio 45267-0559, USA
Exp Biol Med (Maywood) 228:1193-200. 2003..These studies represent the first comprehensive set of data to characterize cloned mice and provide critical information about the long-term effects of somatic cell cloning... - Metabolic and endocrine consequences of social stress in a visible burrow systemKellie L K Tamashiro
Department of Psychiatry, University of Cincinnati Medical Center, 231 Albert Sabin Way, Box 670559, Cincinnati, OH 45267-0559, USA
Physiol Behav 80:683-93. 2004..In summary, the VBS model of chronic social stress is an ethologically relevant animal model and provides a valuable tool for studies of stress-related conditions and pathologies... - Chronic social stress in a changing dietary environmentKellie L K Tamashiro
Department of Psychiatry, North University of Cincinnati 2170 E. Galbraith Road, E-212 Cincinnati, OH 45237, USA
Physiol Behav 89:536-42. 2006.... - Developmental, behavioral, and physiological phenotype of cloned miceKellie L K Tamashiro
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 618, Baltimore, Maryland 21205, USA
Adv Exp Med Biol 591:72-83. 2007..At the moment, the long-term consequences of mammalian cloning remain poorly characterized. Data available thus far suggest that we should use this technology with great caution until numerous questions are addressed and answered... 
Maternal high-fat diet during gestation or suckling differentially affects offspring leptin sensitivity and obesityBo Sun
Department of Physiology and Pathophysiology, Xi an Jiaotong University School of Medicine, Xi an, Shaanxi, People s Republic of China
Diabetes 61:2833-41. 2012..Maternal HF diet during suckling has a greater influence in determining offspring's metabolic phenotype than prenatal HF diet exposure and could provide insight regarding optimal perinatal nutrition for mothers and children...- Prenatal stress or high-fat diet increases susceptibility to diet-induced obesity in rat offspringKellie L K Tamashiro
Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Diabetes 58:1116-25. 2009..In this study, we used an animal model to determine the metabolic consequences of maternal prenatal stress and high-fat feeding on the developing offspring... - Perinatal environment and its influences on metabolic programming of offspringKellie L K Tamashiro
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 618, Baltimore, MD 21205, United States
Physiol Behav 100:560-6. 2010..The paper represents an invited review by a symposium, award winner or keynote speaker at the Society for the Study of Ingestive Behavior [SSIB] Annual Meeting in Portland, July 2009... 
Chronic stress, metabolism, and metabolic syndromeK L Tamashiro
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Stress 14:468-74. 2011..Here, we review data from leading investigators discussing the interrelationship between chronic stress and development of metabolic disorders...- Metabolic syndrome: links to social stress and socioeconomic statusKellie L K Tamashiro
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ann N Y Acad Sci 1231:46-55. 2011.... - Introduction to the special issue. Proceedings from the 2007 Meeting of the Society for the Study of Ingestive BehaviorKellie L K Tamashiro
Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine, Ross 618 720 Rutland Avenue, Baltimore, MD 21205, USA
Physiol Behav 94:635-6. 2008 - Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balanceLiang Yang
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Neurosci 29:179-90. 2009..Together, these results indicate that DMH NPY plays an important role in modulating food intake and energy balance and its dysregulation causes disordered energy balance leading to obesity... - Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5Xiaoju Yang
Department of Medicine, Division of Endocrinology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Biochem Biophys Res Commun 420:570-5. 2012..Taken together, we provide evidence that these glucocorticoid-induced epigenetic alterations have a broader validity in non-neuronal cells and that they may involve the DNA methylation machinery... - Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathologyBagrat Abazyan
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, USA
Biol Psychiatry 68:1172-81. 2010..We evaluated interaction between mutant human disrupted-in-schizophrenia 1 (mhDISC1) and maternal immune activation implicated in schizophrenia and mood disorders... - Nrf2 mediates cancer protection but not prolongevity induced by caloric restrictionKevin J Pearson
Laboratories of Experimental Gerontology, Clinical Investigation, and Immunology and Research Resources Branch, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
Proc Natl Acad Sci U S A 105:2325-30. 2008..However, CR extended lifespan and increased insulin sensitivity similarly in KO and WT mice. These findings identify a molecular pathway that dissociates the prolongevity and anticarcinogenic effects of CR... - Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intakeSu Gao
Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 104:17358-63. 2007..Together, these findings highlight site-specific impacts of hypothalamic ACC activation in leptin's anorectic signaling cascade... - Curt Richter: spontaneous activity and food intakeTimothy H Moran
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Ross 618, Baltimore, MD 21205, USA
Appetite 49:368-75. 2007.... - Cloning and assisted reproductive techniques: influence on early development and adult phenotypeRandall R Sakai
Department of Psychiatry, University of Cincinnati Medical Center, 2170 E Galbraith Road E 212, Cincinnati, OH 45237, USA
Birth Defects Res C Embryo Today 75:151-62. 2005..In this article, we review studies examining the phenotype of animals generated by cloning and various ART, and discuss clinical implications of these findings... - Androgenic influences on behavior, body weight, and body composition in a model of chronic social stressMary M N Nguyen
Neuroscience Graduate Program and Department of Psychiatry, University of Cincinnati, 2170 East Galbraith Road, Cincinnati, OH 45237 0506, USA
Endocrinology 148:6145-56. 2007..Overall, these data suggest that constant androgen concentrations in SUB animals do not prevent weight loss and changes in body composition during stress but do so during recovery...
Research Grants
- Social stress-induced changes in energy homeostasisKELLIE TAMASHIRO; Fiscal Year: 2005..abstract_text> ..
- Influences of the prenatal environment on metabolic programmingKELLIE TAMASHIRO; Fiscal Year: 2007....