Taha Taha

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. pmc Child mortality levels and trends by HIV status in Blantyre, Malawi: 1989-2009
    Taha E Taha
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 61:226-34. 2012
  2. pmc Trends in birth weight and gestational age for infants born to HIV-infected, antiretroviral treatment-naive women in Malawi
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 31:481-6. 2012
  3. pmc Micronutrient malnutrition and wasting in adults with pulmonary tuberculosis with and without HIV co-infection in Malawi
    Monique van Lettow
    Johns Hopkins University School of Medicine, Baltimore, USA
    BMC Infect Dis 4:61. 2004
  4. ncbi request reprint HIV infection and disturbances of vaginal flora during pregnancy
    T E Taha
    School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Acquir Immune Defic Syndr Hum Retrovirol 20:52-9. 1999
  5. doi request reprint Postnatal HIV-1 transmission after cessation of infant extended antiretroviral prophylaxis and effect of maternal highly active antiretroviral therapy
    Taha E Taha
    Dept of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    J Infect Dis 200:1490-7. 2009
  6. ncbi request reprint Short postexposure prophylaxis in newborn babies to reduce mother-to-child transmission of HIV-1: NVAZ randomised clinical trial
    Taha E Taha
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Lancet 362:1171-7. 2003
  7. ncbi request reprint Nevirapine and zidovudine at birth to reduce perinatal transmission of HIV in an African setting: a randomized controlled trial
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    JAMA 292:202-9. 2004
  8. ncbi request reprint Late postnatal transmission of HIV-1 and associated factors
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Infect Dis 196:10-4. 2007
  9. ncbi request reprint Gender differences in perinatal HIV acquisition among African infants
    Taha E Taha
    Infectious Diseases Program, Department of Epidemiology, Bloomberg School of Public Health, MBBS, Room E7138, 615 N Wolfe St, Baltimore, MD 21205, USA
    Pediatrics 115:e167-72. 2005
  10. ncbi request reprint Haematological changes in African children who received short-term prophylaxis with nevirapine and zidovudine at birth
    Taha E Taha
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Ann Trop Paediatr 24:301-9. 2004

Research Grants

  1. The Malawi Clinical Trials Unit
    Taha Taha; Fiscal Year: 2007
  2. HIV PREVENTION TRIALS UNIT - MALAWI
    Taha Taha; Fiscal Year: 2006

Collaborators

Detail Information

Publications65

  1. pmc Child mortality levels and trends by HIV status in Blantyre, Malawi: 1989-2009
    Taha E Taha
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 61:226-34. 2012
    ..We examined mortality levels and trends over a period of ∼20 years among HIV-unexposed and -exposed children in Blantyre, Malawi...
  2. pmc Trends in birth weight and gestational age for infants born to HIV-infected, antiretroviral treatment-naive women in Malawi
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 31:481-6. 2012
    ..We analyzed birth outcomes among infants of treatment-naive, HIV-infected women from a series of mother-to-child transmission of HIV studies in Blantyre, Malawi...
  3. pmc Micronutrient malnutrition and wasting in adults with pulmonary tuberculosis with and without HIV co-infection in Malawi
    Monique van Lettow
    Johns Hopkins University School of Medicine, Baltimore, USA
    BMC Infect Dis 4:61. 2004
    ..We hypothesized that micronutrient malnutrition is associated with wasting and higher plasma human immunodeficiency virus (HIV) load in adults with pulmonary tuberculosis...
  4. ncbi request reprint HIV infection and disturbances of vaginal flora during pregnancy
    T E Taha
    School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Acquir Immune Defic Syndr Hum Retrovirol 20:52-9. 1999
    ..Although these studies were cross-sectional, our data suggest that BV could be associated with increased susceptibility to HIV infection...
  5. doi request reprint Postnatal HIV-1 transmission after cessation of infant extended antiretroviral prophylaxis and effect of maternal highly active antiretroviral therapy
    Taha E Taha
    Dept of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    J Infect Dis 200:1490-7. 2009
    ..The association between postnatal human immunodeficiency virus type 1 (HIV-1) transmission and maternal highly active antiretroviral therapy (HAART) after infant extended antiretroviral prophylaxis was assessed...
  6. ncbi request reprint Short postexposure prophylaxis in newborn babies to reduce mother-to-child transmission of HIV-1: NVAZ randomised clinical trial
    Taha E Taha
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Lancet 362:1171-7. 2003
    ..We aimed to determine whether post-exposure prophylaxis of nevirapine plus zidovudine given to babies only reduced transmission of HIV more than did a regimen of nevirapine alone...
  7. ncbi request reprint Nevirapine and zidovudine at birth to reduce perinatal transmission of HIV in an African setting: a randomized controlled trial
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    JAMA 292:202-9. 2004
    ....
  8. ncbi request reprint Late postnatal transmission of HIV-1 and associated factors
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Infect Dis 196:10-4. 2007
    ..The present study was undertaken to determine the risk and timing of late postnatal transmission (LPT) of human immunodeficiency virus type 1 (HIV-1)...
  9. ncbi request reprint Gender differences in perinatal HIV acquisition among African infants
    Taha E Taha
    Infectious Diseases Program, Department of Epidemiology, Bloomberg School of Public Health, MBBS, Room E7138, 615 N Wolfe St, Baltimore, MD 21205, USA
    Pediatrics 115:e167-72. 2005
    ..We investigated gender-specific risks of mother-to-child transmission (MTCT) at birth and at 6 to 8 weeks among infants born to HIV-infected African women...
  10. ncbi request reprint Haematological changes in African children who received short-term prophylaxis with nevirapine and zidovudine at birth
    Taha E Taha
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Ann Trop Paediatr 24:301-9. 2004
    ..Antiretroviral prophylaxis appeared to protect against anaemia and child death. Short regimens of antiretrovirals to prevent MTCT of HIV are not associated with long-term adverse haematological changes...
  11. ncbi request reprint Safety, acceptability, and potential efficacy of a topical penile microbicide wipe
    Taha E Taha
    Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 39:347-53. 2005
    ..This penile wipe is safe, acceptable, and can decrease the frequency of penile colonization with microorganisms. The clinical relevance remains to be determined in larger clinical trials...
  12. pmc The impact of breastfeeding on the health of HIV-positive mothers and their children in sub-Saharan Africa
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Bull World Health Organ 84:546-54. 2006
    ..We assessed the impact of breastfeeding by women infected with human immunodeficiency virus (HIV)-1 on their morbidity and risk of mortality and on the mortality of their children...
  13. ncbi request reprint A phase III clinical trial of antibiotics to reduce chorioamnionitis-related perinatal HIV-1 transmission
    Taha E Taha
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    AIDS 20:1313-21. 2006
    ..A multisite study was conducted in Africa to assess the efficacy of antibiotics to reduce mother-to-child transmission (MTCT) of HIV-1...
  14. ncbi request reprint The effect of human immunodeficiency virus and breastfeeding on the nutritional status of African children
    Taha Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 29:514-8. 2010
    ..We longitudinally assessed the nutritional status and determined its association with HIV infection and breast-feeding among Malawian children...
  15. doi request reprint Mother-to-child transmission of HIV-1 in sub-Saharan Africa: past, present and future challenges
    Taha E Taha
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States
    Life Sci 88:917-21. 2011
    ..Reviewing past and present achievements assists in focusing future research and development of prevention programs...
  16. ncbi request reprint Mortality after the first year of life among human immunodeficiency virus type 1-infected and uninfected children
    T E Taha
    Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 18:689-94. 1999
    ..HIV-infected and uninfected children who survived their first year of life were prospectively followed in Malawi to assess levels of mortality and related risk factors during the second and third years of life...
  17. ncbi request reprint Association of HIV-1 load and CD4 lymphocyte count with mortality among untreated African children over one year of age
    T E Taha
    Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    AIDS 14:453-9. 2000
    ..To examine the association of viral load and CD4 lymphocyte count with mortality among HIV-infected children over one year of age...
  18. ncbi request reprint Genital tract infections and perinatal transmission of HIV
    T E Taha
    School of Hygiene and Public Health, Johns Hopkins University, 615 N Wolfe Street, Baltimore, Maryland 21205, USA
    Ann N Y Acad Sci 918:84-98. 2000
    ..In addition, antibiotics could reduce infectious causes of morbidity and mortality in infant and mother...
  19. doi request reprint Postexposure prophylaxis of breastfeeding HIV-exposed infants with antiretroviral drugs to age 14 weeks: updated efficacy results of the PEPI-Malawi trial
    Taha E Taha
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 57:319-25. 2011
    ..This analysis updates and extends efficacy estimates of the PEPI-Malawi trial through age 24 months at study completion in September 2009...
  20. pmc Effects of cessation of breastfeeding in HIV-1-exposed, uninfected children in Malawi
    Taha E Taha
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Clin Infect Dis 53:388-95. 2011
    ..We assessed morbidity rates during short intervals that accompanied weaning and cumulative mortality among HIV-exposed, uninfected infants enrolled in the postexposure prophylaxis of infants in Malawi (PEPI-Malawi) trial...
  21. ncbi request reprint Resistance after single-dose nevirapine prophylaxis emerges in a high proportion of Malawian newborns
    Susan H Eshleman
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    AIDS 19:2167-9. 2005
    ..Nevirapine resistance was more frequent in infants with subtype C than with subtypes A and D (87 versus 50%, P = 0.016)...
  22. ncbi request reprint Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP
    Susan H Eshleman
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Infect Dis 192:30-6. 2005
    ..Here, we evaluate the rate of NVP resistance mutations in women with subtype C...
  23. ncbi request reprint HIV incidence among women of reproductive age in Malawi and Zimbabwe
    Newton Kumwenda
    Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Sex Transm Dis 33:646-51. 2006
    ..The objective of this study was to determine the incidence of HIV-1...
  24. ncbi request reprint Iron status and indicators of human immunodeficiency virus disease severity among pregnant women in Malawi
    R D Semba
    Department of Ophthalmology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, MD 21205, USA
    Clin Infect Dis 32:1496-9. 2001
    ..In contrast to previous studies, these data suggest that iron status is not related to markers of HIV disease severity in pregnant women in Africa...
  25. ncbi request reprint Morbidity among human immunodeficiency virus-1-infected and -uninfected African children
    T E Taha
    Infectious Diseases Program, Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland
    Pediatrics 106:E77. 2000
    ..To assess patterns of morbidity and associated factors in late infancy and early childhood among human immunodeficiency virus (HIV)-infected and -uninfected African children...
  26. ncbi request reprint The role of men in women's acceptance of an intravaginal gel in a randomized clinical trial in Blantyre, Malawi: a qualitative and quantitative analysis
    M L Salter
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    AIDS Care 20:853-62. 2008
    ..These results indicate that female perceptions of male partner acceptability and actual male partner acceptability need to be considered when addressing female-controlled product acceptability and use...
  27. ncbi request reprint Epidemiology and microbiology of subclinical mastitis among HIV-infected women in Malawi
    V Nussenblatt
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Int J STD AIDS 16:227-32. 2005
    ..02). Subclinical mastitis is prevalent among breastfeeding mothers and further studies are needed to characterize the differences between infectious and non-infectious subclinical mastitis...
  28. ncbi request reprint HIV transmission through breastfeeding: a study in Malawi
    P G Miotti
    Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD, USA
    JAMA 282:744-9. 1999
    ..Understanding the risk of human immunodeficiency virus (HIV) transmission through breastfeeding is essential for advising HIV-infected mothers and formulating public health policy recommendations...
  29. ncbi request reprint Assessment of iron status using plasma transferrin receptor in pregnant women with and without human immunodeficiency virus infection in Malawi
    R D Semba
    Departments of Ophthalmology and Epidemiology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, Maryland, USA
    Eur J Clin Nutr 54:872-7. 2000
    ..Although anemia is highly prevalent during pregnancy and is common during human immunodeficiency virus (HIV) infection, anemia and iron status have not been well characterized in HIV-infected pregnant women...
  30. ncbi request reprint Human immunodeficiency virus load in breast milk, mastitis, and mother-to-child transmission of human immunodeficiency virus type 1
    R D Semba
    Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    J Infect Dis 180:93-8. 1999
    ..0001). Mastitis and breast milk HIV-1 load may increase the risk of vertical transmission of HIV-1 through breast-feeding...
  31. ncbi request reprint Pharmacokinetics and safety of tenofovir in HIV-infected women during labor and their infants during the first week of life
    Mark Mirochnick
    Department of Pediatrics, Boston University School of Medicine, Boston, MA Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD HIV AIDS Research Department, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Rio Grande do Sul, Brazil Department of Pediatrics, David Geffen UCLA School of Medicine, Los Angeles, CA Malawi College of Medicine, Blantyre, Malawi Infectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janiero, Brazil Department of Pediatrics, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Serviço de Infectologia, Hospital Nossa Senhora da Conceicao, Porto Alegre, Rio Grande do Sul, Brazil Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD Gilead Sciences, Foster City, CA Statistical Center for HIV AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD Family Health International, Durham, NC Makerere University Johns Hopkins University Research Collaboration, Kampala, Brazil
    J Acquir Immune Defic Syndr 65:33-41. 2014
    ..Data describing the pharmacokinetics and safety of tenofovir in neonates are lacking...
  32. ncbi request reprint Effect of antibiotic treatment of subclinical mastitis on human immunodeficiency virus type 1 RNA in human milk
    V Nussenblatt
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Trop Pediatr 52:311-5. 2006
    ..These findings have important implications regarding how mothers should be counselled on safety of resuming breastfeeding after resolution of subclinical mastitis...
  33. ncbi request reprint Malnutrition and the severity of lung disease in adults with pulmonary tuberculosis in Malawi
    M Van Lettow
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Int J Tuberc Lung Dis 8:211-7. 2004
    ..Zomba Central Hospital, Zomba, Malawi...
  34. ncbi request reprint HIV-1 incidence among male workers at a sugar estate in rural Malawi
    N I Kumwenda
    Infectious Diseases Program, Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, 615 N. Wolfe Street, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 27:202-8. 2001
    ..In addition to conventional educational messages to reduce risky sexual behavior, treatment of other sexually transmitted diseases should be considered...
  35. pmc Mastitis and immunological factors in breast milk of lactating women in Malawi
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 6:671-4. 1999
    ..0001); and RANTES, 82 versus 3 ng/liter (P < 0.0001). Elevated sodium concentrations in breast milk are associated with an increase in levels of some immunological and inflammatory factors in breast milk...
  36. ncbi request reprint Impact of vitamin A supplementation on anaemia and plasma erythropoietin concentrations in pregnant women: a controlled clinical trial
    R D Semba
    Department of Ophthalmology, and Center for Human Nutrition, The Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, Maryland, USA
    Eur J Haematol 66:389-95. 2001
    ..Although studies suggest that vitamin A or its metabolites influence the synthesis of erythropoietin in vitro and in animal models, it is unclear whether vitamin A supplementation increases plasma erythropoietin concentrations in humans...
  37. pmc Risk factors for late postnatal transmission of human immunodeficiency virus type 1 in sub-Saharan Africa
    Charles Chasela
    University of North Carolina Project, Kamuzu Central Hospital, Lilongwe, Malawi
    Pediatr Infect Dis J 27:251-6. 2008
    ..We conducted secondary data analyses of a clinical trial (HIVNET 024) to assess risk factors for late postnatal transmission (LPT) of human immunodeficiency virus type 1 (HIV-1) through breast-feeding...
  38. doi request reprint Comparison of LigAmp and an ASPCR assay for detection and quantification of K103N-containing HIV variants
    Jessica D Church
    Johns Hopkins University, Baltimore, Maryland 21205, USA
    AIDS Res Hum Retroviruses 24:595-605. 2008
    ..Further studies are needed to compare performance of assays for detection and quantification of HIV drug resistance mutations in clinical samples...
  39. ncbi request reprint Natural history and risk factors associated with early and established HIV type 1 infection among reproductive-age women in Malawi
    Johnstone J Kumwenda
    College of Medicine, University of Malawi, Chichiri
    Clin Infect Dis 46:1913-20. 2008
    ..We also assessed the association of injectable hormonal contraceptive use with HIV-1 infection...
  40. doi request reprint HIV-1 incidence among women of reproductive age in Malawi
    N I Kumwenda
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Int J STD AIDS 19:339-41. 2008
    ..Young age, using hormonal injectable contraceptives and bacterial vaginosis were the main predictors of HIV acquisition. The incidence of HIV continues to be high among women in Malawi, and young women appear to be at higher risk...
  41. doi request reprint Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission
    Newton I Kumwenda
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    N Engl J Med 359:119-29. 2008
    ..Effective strategies are urgently needed to reduce mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) through breast-feeding in resource-limited settings...
  42. pmc Nutritional indicators of adverse pregnancy outcomes and mother-to-child transmission of HIV among HIV-infected women
    Saurabh Mehta
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 87:1639-49. 2008
    ..Poor nutrition may be associated with mother-to-child transmission (MTCT) of HIV and other adverse pregnancy outcomes...
  43. ncbi request reprint The HPTN 024 Study: the efficacy of antibiotics to prevent chorioamnionitis and preterm birth
    Robert L Goldenberg
    Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
    Am J Obstet Gynecol 194:650-61. 2006
    ..The use of antibiotics to prevent preterm birth has achieved mixed results. Our goal in this study was to determine if antibiotics given prenatally and during labor reduce the incidence of preterm birth and histologic chorioamnionitis...
  44. pmc Morbidity and mortality among a cohort of human immunodeficiency virus type 1-infected and uninfected pregnant women and their infants from Malawi, Zambia, and Tanzania
    David Chilongozi
    University of North Carolina Project, Lilongwe, Malawi
    Pediatr Infect Dis J 27:808-14. 2008
    ..Morbidity and mortality patterns among pregnant women and their infants (before antiretroviral therapy was widely available) determines HIV-1 diagnostic, monitoring, and care interventions...
  45. ncbi request reprint Antenatal vitamin A supplementation increases birth weight and decreases anemia among infants born to human immunodeficiency virus-infected women in Malawi
    Newton Kumwenda
    Department of Epidemiology and Ophthalmology, Johns Hopkins University School of Hygiene and Public Health and School of Medicine, Baltimore, MD, USA
    Clin Infect Dis 35:618-24. 2002
    ..6% and 27.8% (P=.76) and 27.7% and 32.8% (P=.21). Receipt of vitamin A improved birth weight and neonatal growth and reduced anemia, but it did not affect perinatal HIV transmission...
  46. ncbi request reprint Three surveys of HIV-1 prevalence and risk factors among men working at a sugar estate in Malawi
    Newton I Kumwenda
    Infectious Diseases Program, Department of Epidemiology, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    Sex Transm Dis 29:366-71. 2002
    ..HIV-1 surveys in defined populations identify underlying risks and trends useful to mount interventions...
  47. ncbi request reprint Effect of HIV-1 antiretroviral prophylaxis on hepatic and hematological parameters of African infants
    Taha E Taha
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    AIDS 16:851-8. 2002
    ..To measure hepatic and hematological parameters among neonates randomized to receive ultra-short antiretroviral regimens...
  48. ncbi request reprint Nonoxynol-9 100 mg gel: multi-site safety study from sub-Saharan Africa
    Irving F Hoffman
    Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC 27599, USA
    AIDS 18:2191-5. 2004
    ..To evaluate the safety of 100 mg nonoxynol-9 (N-9) gel, a vaginal microbicide, on the genital mucosa of women from Malawi and Zimbabwe in preparation for a phase III efficacy study...
  49. ncbi request reprint Predictors of stillbirth in sub-saharan Africa
    Benjamin H Chi
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Obstet Gynecol 110:989-97. 2007
    ..To describe the incidence and predictors of stillbirth in a predominantly human immunodeficiency virus (HIV)-infected African cohort...
  50. ncbi request reprint Status of carotenoids, vitamin A, and vitamin E in the mother-infant dyad and anthropometric status of infants in Malawi
    Barbara Dancheck
    Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Health Popul Nutr 23:343-50. 2005
    ....
  51. ncbi request reprint Higher in utero and perinatal HIV infection risk in girls than boys
    Robert J Biggar
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Division of Health and Human Services, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 41:509-13. 2006
    ..This study analyzed mother-to-child HIV transmission rates by sex and exposure time for babies born to HIV-infected, untreated African women...
  52. ncbi request reprint Association between the replication capacity and mother-to-child transmission of HIV-1, in antiretroviral drug-naive Malawian women
    Susan H Eshleman
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Infect Dis 193:1512-5. 2006
    ..45 for each 10% increase in replication capacity [95% confidence interval, 1.11-1.90]; P = .0063), after adjustment for maternal HIV-1 load and other factors...
  53. ncbi request reprint Quantitative analysis of HIV-1 variants with the K103N resistance mutation after single-dose nevirapine in women with HIV-1 subtypes A, C, and D
    Tamara S Flys
    Department of Pathology, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 42:610-3. 2006
    ..We used a sensitive point mutation assay, LigAmp, to detect and quantify K103N-containing variants in African women who received single-dose nevirapine (NVP) to prevent mother-to-child HIV-1 transmission...
  54. ncbi request reprint Development of nevirapine resistance in infants is reduced by use of infant-only single-dose nevirapine plus zidovudine postexposure prophylaxis for the prevention of mother-to-child transmission of HIV-1
    Susan H Eshleman
    Johns Hopkins University, Baltimore, MD 21205, USA
    J Infect Dis 193:479-81. 2006
    ..20/23 [87%]; P < .001). The risk of MTCT of HIV-1 was comparable with these regimens. Infant-only prophylaxis also eliminates the development of NVP resistance in mothers...
  55. ncbi request reprint Comparison of HIV-1 mother-to-child transmission after single-dose nevirapine prophylaxis among African women with subtypes A, C, and D
    Susan H Eshleman
    J Acquir Immune Defic Syndr 42:518-21. 2006
  56. ncbi request reprint Timing of maternal and neonatal dosing of nevirapine and the risk of mother-to-child transmission of HIV-1: HIVNET 024
    Benjamin H Chi
    University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Birmingham, Alabama, USA
    AIDS 19:1857-64. 2005
    ..We analyzed data from a multicenter clinical trial to determine whether timing of maternal or infant NVP was associated with MTCT between delivery and 6 weeks of age (intrapartum/early postnatal transmission; I/EP)...
  57. ncbi request reprint HPTN 024 study: histologic chorioamnionitis, antibiotics and adverse infant outcomes in a predominantly HIV-1-infected African population
    Robert L Goldenberg
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35233 1602, USA
    Am J Obstet Gynecol 195:1065-74. 2006
    ..Histologic chorioamnionitis has been associated with preterm birth and low birthweight. Our goal was to evaluate the relationship between polymorphonuclear cell and mononuclear cell placental infiltrations and adverse infant outcomes...
  58. pmc Affordable, abbreviated roche monitor assay for quantification of human immunodeficiency virus type 1 RNA in plasma
    Susan A Fiscus
    Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Clin Microbiol 43:4200-2. 2005
    ..To make this approach feasible, Roche would have to provide additional lysis buffer and master mix...
  59. pmc Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D
    Jessica D Church
    Department of Pathology, The Johns Hopkins Medical Institutions, Ross Bldg 646, 720 Rutland Ave, Baltimore, MD 21205, USA
    J Mol Diagn 8:430-2; quiz 527. 2006
    ..Further studies are needed to compare the sensitivity of different assays for detection of HIV-1 drug resistance mutations and to determine the clinical relevance of HIV-1 minority variants...
  60. ncbi request reprint Fetal fibronectin and adverse infant outcomes in a predominantly human immunodeficiency virus-infected African population: a randomized controlled trial
    Robert L Goldenberg
    Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 1500 6th Avenue South, Birmingham, AL 35233, USA
    Obstet Gynecol 109:392-401. 2007
    ..To evaluate the relationship between fetal fibronectin and preterm birth and maternal-to-child transmission of human immunodeficiency virus (HIV) in an African population of predominantly HIV-infected women...
  61. ncbi request reprint Breast milk retinol concentrations are not associated with systemic inflammation among breast-feeding women in Malawi
    Barbara Dancheck
    Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Nutr 135:223-6. 2005
    ..22 and P = 0.86, respectively). These findings suggest that breast milk retinol concentrations are not affected by systemic inflammation...
  62. ncbi request reprint HIV type 1 variants with nevirapine resistance mutations are rarely detected in antiretroviral drug-naive African women with subtypes A, C, and D
    Jessica D Church
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    AIDS Res Hum Retroviruses 23:764-8. 2007
    ....
  63. ncbi request reprint HIV seroreversion time in HIV-1-uninfected children born to HIV-1-infected mothers in Malawi
    Jyoti Gulia
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 46:332-7. 2007
    ..To study temporal changes in HIV-1 seroreversion (change in reactivity of HIV serology from positive to negative) in uninfected infants born to HIV-1-infected mothers...
  64. ncbi request reprint HIV-1 prevalence and herpes simplex virus 2, hepatitis C virus, and hepatitis B virus infections among male workers at a sugar estate in Malawi
    Siobhan Sutcliffe
    Infectious Diseases Program, Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Acquir Immune Defic Syndr 31:90-7. 2002
    ..4% among control subjects (p =.46). HSV-2 infection is significantly associated with prevalent HIV-1 infection in this population. Therefore, preventive measures for HSV-2 and HIV infection should be emphasized...
  65. ncbi request reprint Human papillomavirus seroprevalence among young male and female drug users
    Sabrina S Plitt
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Sex Transm Dis 34:676-80. 2007
    ..To determine seroprevalence and correlates of exposure to HPV 16, 18, and 53 among 15- to 30-year-old drug users in Baltimore, MD...

Research Grants3

  1. The Malawi Clinical Trials Unit
    Taha Taha; Fiscal Year: 2007
    ..administrative component: ..
  2. HIV PREVENTION TRIALS UNIT - MALAWI
    Taha Taha; Fiscal Year: 2006
    ..We intend to continue these studies and to expand to additional sites. ..