Research Topics
| R J StoltzfusSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Publications
Measuring performance: a strategy to improve programsRebecca J Stoltzfus
Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 132:845S-8S. 2002..To be useful, evaluation findings must be disseminated, usually to multiple audiences. This requires allocation of time and resources and attention to the needs of various stakeholders...- Effects of the Zanzibar school-based deworming program on iron status of childrenR J Stoltzfus
Center for Human Nutrition, Department of International Health, The Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
Am J Clin Nutr 68:179-86. 1998..Where hookworm is heavily endemic, deworming programs can improve iron status and prevent moderate and severe anemia, but deworming may be needed at least twice yearly... - Epidemiology of iron deficiency anemia in Zanzibari schoolchildren: the importance of hookwormsR J Stoltzfus
Center for Human Nutrition, Department of International Health, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
Am J Clin Nutr 65:153-9. 1997..We conclude that anthelminthic therapy is an essential component of anemia control in schoolchildren in whom hookworms are endemic, and should be complemented with school-based iron supplementation... 
Effects of iron supplementation and anthelmintic treatment on motor and language development of preschool children in Zanzibar: double blind, placebo controlled studyR J Stoltzfus
Department of I nternational Health, Johns Hopkins University, Baltimore, MD 21205-2179, USA
BMJ 323:1389-93. 2001..Mebendazole had a positive effect on motor and language development, but this was not statistically significant...- Clinical pallor is useful to detect severe anemia in populations where anemia is prevalent and severeR J Stoltzfus
Department of International Health, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
J Nutr 129:1675-81. 1999..Usually, the majority of persons with severe anemia will be detected at practically no cost. Many people who are not severely anemic will also receive treatment, but the costs of this error are low compared to the benefits... - Epidemiology of anemia among 4- to 17-month-old children living in south central NepalE H Siegel
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Eur J Clin Nutr 60:228-35. 2006..To describe the distribution of hemoglobin and prevalence of anemia in Nepali children living in the Terai region by potential risk factors for deficiency... - Growth indices, anemia, and diet independently predict motor milestone acquisition of infants in south central NepalEmily H Siegel
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
J Nutr 135:2840-4. 2005..We conclude that growth, anemia, and diet are independently associated with delays in the onset of bipedal locomotion among young Nepali children... - Helicobacter pylori infection is associated with severe anemia of pregnancy on Pemba Island, ZanzibarTamer H Farag
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Am J Trop Med Hyg 76:541-8. 2007..Further research is needed to establish causality because high worldwide prevalence means that even a small associated risk would be of public health significance... - Unexpectedly low prevalence of Helicobacter pylori infection among pregnant women on Pemba Island, ZanzibarTamer H Farag
Department of International Health, Bloomberg School of Public Health, Johns Hopkins, University, Baltimore, MD, USA
Trans R Soc Trop Med Hyg 101:915-22. 2007..The reason for very low prevalence should be investigated further because the discovery of bacterial or dietary factors that limit infection in this population could have useful public health applications... - Vitamin A and the nursing mother-infant dyad: evidence for interventionRebecca J Stoltzfus
Center for Human Nutrition, Department of International Health, The Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
Adv Exp Med Biol 503:39-47. 2002..In sum, the probable benefits of improving the vitamin A status of the breastfeeding mother and her baby are substantial, but to achieve these benefits, more aggressive interventions will be needed... - Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trialJames M Tielsch
Center for Human Nutrition and the Sight and Life Institute, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
Lancet 367:144-52. 2006..Supplementation with iron and folic acid alleviates severe anaemia and enhances neurodevelopment in deficient populations, but little is known about the risks of mortality and morbidity associated with supplementation... - Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trialSunil Sazawal
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
Lancet 367:133-43. 2006..However, supplementation of those who are not iron deficient might be harmful. As such, current guidelines for universal supplementation with iron and folic acid should be revised... 
Beneficial effects of zinc supplementation on head circumference of Nepalese infants and toddlers: a randomized controlled trialP J Surkan
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Eur J Clin Nutr 66:836-42. 2012..To assess the effects of micronutrient supplementation on head circumference of rural Nepali infants and children...- Hyporetinolemia, illness symptoms, and acute phase protein response in pregnant women with and without night blindnessP Christian
Center for Human Nutrition, Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Clin Nutr 67:1237-43. 1998..AGP and CRP may provide useful information about the effect of reported illness on hyporetinolemia in pregnancy. Infection-related hyporetinolemia may predispose women to night blindness during pregnancy in Nepal... - Iron-deficiency anemia: reexamining the nature and magnitude of the public health problem. Summary: implications for research and programsR J Stoltzfus
Center for Human Nutrition, Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 131:697S-700S; discussion 700S-701S. 2001..The simple model depicting severe anemia and tissue iron deficiency as distinct but overlapping entities with distinct functional outcomes is presented and may be useful in designing and evaluating programs... - Total body iron in HIV-positive and HIV-negative Zimbabwean newborns strongly predicts anemia throughout infancy and is predicted by maternal hemoglobin concentrationMelissa F Miller
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
J Nutr 133:3461-8. 2003..Babies born with low birthweight or to mothers with low hemoglobin are born with less TBI, which confers a substantially greater risk of anemia from 3 to 12 mo of age... - Effect of daily zinc supplementation on child mortality in southern Nepal: a community-based, cluster randomised, placebo-controlled trialJames M Tielsch
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2013, USA
Lancet 370:1230-9. 2007..However, whether routine supplementation would decrease morbidity and mortality in populations with zinc deficiency is unclear. We assessed the effect of daily zinc supplementation on children in southern Nepal... - Low-dose daily iron supplementation for 12 months does not increase the prevalence of malarial infection or density of parasites in young Zanzibari childrenTsedal Mebrahtu
Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Nutr 134:3037-41. 2004..We conclude that in this environment of high malaria transmission, daily oral low-dose supplementation of iron for 12 mo did not affect the prevalence of malaria infection or parasite density... - Measurement of blood loss at childbirth and postpartumJ A Kavle
Johns Hopkins University Bloomberg School of Public Health, Department of International Health, Center for Human Nutrition, Baltimore, USA
Int J Gynaecol Obstet 95:24-8. 2006..CONCLUSION: This study may prompt further investigation, as no comparable data exist for developing countries where maternal mortality is high and severe anemia prevalent... - Implications of the Institute of Medicine weight gain recommendations for preventing adverse pregnancy outcomes in black and white womenL E Caulfield
Center for Human Nutrition, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205, USA
Am J Public Health 88:1168-74. 1998.... - A comparison of methods for detecting the eggs of Ascaris, Trichuris, and hookworm in infant stool, and the epidemiology of infection in Zanzibari infantsDavid Goodman
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Am J Trop Med Hyg 76:725-31. 2007..4%, while at 10 and 11 months of age the mean prevalence was 43.4%. Village prevalence varied from 3.6% to 43.8%. Infant geohelminth infection can occur at a high prevalence, and what method is best depends on research specifics... - Association between anaemia during pregnancy and blood loss at and after delivery among women with vaginal births in Pemba Island, Zanzibar, TanzaniaJustine A Kavle
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Health Popul Nutr 26:232-40. 2008.... - Daily supplementation with iron plus folic acid, zinc, and their combination is not associated with younger age at first walking unassisted in malnourished preschool children from a deficient population in rural NepalJoanne Katz
Department of International Health and 6Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 140:1317-21. 2010..5 cm [60.6 d, (95% CI: 28.5, 92.6)]. Risks and benefits of universal iron+folic acid supplementation of infants beyond improved hematologic status deserve further consideration... - Effect of zinc supplementation on mortality in children aged 1-48 months: a community-based randomised placebo-controlled trialSunil Sazawal
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Lancet 369:927-34. 2007..Our aim was to assess the effects of zinc supplementation on overall mortality in children in Pemba, Zanzibar... - Interactive effects of iron and zinc on biochemical and functional outcomes in supplementation trialsChrista Fischer Walker
Bloomberg School of Public Health, Department of International Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Clin Nutr 82:5-12. 2005..Further research is needed before health policies on joint supplementation programs can be established... - Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool childrenSarah E Cusick
Center for Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Am J Clin Nutr 82:406-12. 2005..Impaired erythropoietin production is one possible mechanism. Plasmodium falciparum malaria has been found to blunt erythropoietin production, whereas vitamin A stimulates erythropoietin production in vitro... - Breastmilk erythropoietin and mother-to-child HIV transmission through breastmilkMelissa Miller
Center for Human Nutrition, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Lancet 360:1246-8. 2002..If our hypothesis is correct, EPO treatment for mother or baby, or both might help prevent transmission of HIV... - Breast-milk vitamin A as an indicator of the vitamin A status of women and infantsR J Stoltzfus
Department of International Health, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Bull World Health Organ 73:703-11. 1995..Breast-milk vitamin A appears to be an especially good indicator for measuring the impact of vitamin A interventions on women and infants, and for this purpose, it is more responsive than other indicators... - Is the exclusion of children under 24 months from anthelmintic treatment justifiable?Antonio Montresor
Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Trans R Soc Trop Med Hyg 96:197-9. 2002..In light of the potential nutritional benefit achieved by regular deworming in this young age-group, the policy that excludes children aged < 24 months from treatment should be re-considered... - Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool childrenRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY UNICEF, Zanzibar, Tanzania
J Nutr 134:348-56. 2004..We hypothesize that incident helminth infections may stimulate inflammatory immune responses in young children, with deleterious effects on protein metabolism and erythropoiesis... - Young Zanzibari children with iron deficiency, iron deficiency anemia, stunting, or malaria have lower motor activity scores and spend less time in locomotionDeanna K Olney
Program in International and Community Nutrition, University of California, Davis, CA 95616, USA
J Nutr 137:2756-62. 2007.... - Iron supplementation of young children: learning from the new evidenceRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Food Nutr Bull 28:S572-84. 2007..Operations research is needed to test this. We conclude with three options for maximizing the benefits and minimizing the risks of iron supplements... - Maternal reports of sleep in 6-18 month-old infants from Nepal and Zanzibar: association with iron deficiency anemia and stuntingKatarzyna Kordas
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, United States
Early Hum Dev 84:389-98. 2008..They may also be fatigued more often, suggesting their sleep may be affected. It is unclear whether fatigue in these infants is due to poor nighttime sleep or if it is compensated for with frequent naps or longer sleep... - The association between lead and micronutrient status, and children's sleep, classroom behavior, and activityKatarzyna Kordas
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
Arch Environ Occup Health 62:105-12. 2007..Anemia was linked to more off-task behaviors, lower physical activity, earlier bedtime, and shorter sleep onset. Researchers should investigate these relationships further, using more sensitive measures... - Iron deficiency: global prevalence and consequencesRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA
Food Nutr Bull 24:S99-103. 2003..4% of the global burden. There is an urgent need to develop effective and sustainable interventions to control iron-deficiency anemia. This will likely not be achieved without substantial involvement of the private sector... - Combined iron and folic acid supplementation with or without zinc reduces time to walking unassisted among Zanzibari infants 5- to 11-mo oldDeanna K Olney
U.S. Department of Agriculture, ARS-Western Human Nutrition Research Center, Davis, CA, USA
J Nutr 136:2427-34. 2006..There were no significant treatment effects on changes in HAZ or WAZ. The effects of treatment on time to walking may have been mediated by improvements in iron status or hemoglobin, but were not mediated through improvements in growth... - Iron deficiency and physical growth predict attainment of walking but not crawling in poorly nourished Zanzibari infantsPatricia K Kariger
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
J Nutr 135:814-9. 2005..In this sample of poorly nourished infants, growth and anemia-iron status are significant predictors of walking, but not crawling... - Effect of maternal and neonatal vitamin A supplementation and other postnatal factors on anemia in Zimbabwean infants: a prospective, randomized studyMelissa F Miller
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
Am J Clin Nutr 84:212-22. 2006..Anemia is prevalent in infants in developing countries. Its etiology is multifactorial and includes vitamin A deficiency... - Iron and zinc supplementation does not improve parent or teacher ratings of behavior in first grade Mexican children exposed to leadKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Pediatr 147:632-9. 2005..To determine the efficacy of iron and zinc supplementation on behavior ratings of lead-exposed children... - Hemoglobin and ferritin are currently the most efficient indicators of population response to iron interventions: an analysis of nine randomized controlled trialsZuguo Mei
Division of Nutrition and Physical Activity, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Nutr 135:1974-80. 2005..It is possible that the optimal indicator(s) may differ with age, sex, and pregnancy. There were too few trials in each age and sex group to allow us to explore this question... - Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal studyMelissa F Miller
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
BMC Infect Dis 6:1. 2006..Anemia is common in HIV infection and independently associated with disease progression and mortality. The pathophysiology of HIV-related anemia is not well understood especially in infancy... - New evidence of iron and zinc interplay at the enterocyte and neural tissuesKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
J Nutr 134:1295-8. 2004..We present an overview of iron and zinc absorption and function in neural tissue as one example of possible interactions... - Performance of the Haemoglobin Colour Scale in diagnosing severe and very severe anaemiaAntonio Montresor
World Health Organization, Geneva, Switzerland
Trop Med Int Health 8:619-24. 2003.... - Acceptability and safety of novel infant porridges containing lyophilized meat powder and iron-fortified wheat flourHelena Pachon
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
Food Nutr Bull 28:35-46. 2007..Lyophilized meat powder with iron-fortified wheat flour can be used to produce an infant porridge with bioavailable iron, but its acceptability and safety are unknown... - Iron and ascorbic Acid: proposed fortification levels and recommended iron compoundsSean R Lynch
Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23501, USA
J Nutr 133:2978S-84S. 2003..There is a need to develop alternative strategies for improving iron bioavailability in complementary foods because it may not be possible to preserve ascorbic acid activity in many of them... - Geophagia is not associated with Trichuris or hookworm transmission in Zanzibar, TanzaniaSera L Young
Cornell University, Division of Nutritional Sciences, International Nutrition, Savage Hall, Ithaca, NY 14853, USA
Trans R Soc Trop Med Hyg 101:766-72. 2007.... - New evidence that iron supplementation during pregnancy improves birth weight: new scientific questionsKathleen M Rasmussen
Am J Clin Nutr 78:673-4. 2003 - Iron and/or zinc supplementation did not reduce blood lead concentrations in children in a randomized, placebo-controlled trialJorge L Rosado
Department of Psychology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
J Nutr 136:2378-83. 2006..Zinc supplementation did not reduce PbBs independently of zinc nutritional status. Neither iron nor zinc can be recommended as the sole treatment for lead-exposed school children... - Blood lead, anemia, and short stature are independently associated with cognitive performance in Mexican school childrenKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Nutr 134:363-71. 2004.... - Deficits in cognitive function and achievement in Mexican first-graders with low blood lead concentrationsKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Environ Res 100:371-86. 2006..Together with other recent findings, these results add to the empirical base of support available for evaluating the adequacy of current screening guidelines and for motivating efforts at primary prevention of childhood lead exposure...