Robert D Stevens

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint Prognosis in severe brain injury
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 41:1104-23. 2013
  2. pmc Hormonal status in protracted critical illness and in-hospital mortality
    Tarek Sharshar
    Department of Intensive Care Medicine, AP HP, Raymond Poincare Hospital, University Versailles Saint Quentin en Yvelines, 104 Bd Raymond Poincaré, Garches F 92380, France
    Crit Care 15:R47. 2011
  3. pmc Hyperglycaemia and apoptosis of microglial cells in human septic shock
    Andrea Polito
    General Intensive Care Medicine, Raymond Poincare Hospital, University of Versailles Saint Quentin en Yvelines, 104 Boulevard R Poincaré, Garches, France
    Crit Care 15:R131. 2011
  4. doi request reprint Neurologic critical care. Preface
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurol Clin 26:xiii-xv. 2008
  5. ncbi request reprint Coma, delirium, and cognitive dysfunction in critical illness
    Robert D Stevens
    Department of Anesthesiology, Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Crit Care Clin 22:787-804; abstract x. 2006
  6. doi request reprint Brain imaging in intensive care medicine
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Semin Neurol 28:631-44. 2008
  7. ncbi request reprint The role of mechanical ventilation in acute brain injury
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Neurol Clin 26:543-63, x. 2008
  8. ncbi request reprint The systemic implications of aneurysmal subarachnoid hemorrhage
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurol Sci 261:143-56. 2007
  9. ncbi request reprint Neuromuscular dysfunction acquired in critical illness: a systematic review
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 8 140, Baltimore, MD 21287, USA
    Intensive Care Med 33:1876-91. 2007
  10. ncbi request reprint Types of brain dysfunction in critical illness
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurol Clin 26:469-86, ix. 2008

Collaborators

Detail Information

Publications44

  1. doi request reprint Prognosis in severe brain injury
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 41:1104-23. 2013
    ..The prediction of neurologic outcome is a fundamental concern in the resuscitation of patients with severe brain injury...
  2. pmc Hormonal status in protracted critical illness and in-hospital mortality
    Tarek Sharshar
    Department of Intensive Care Medicine, AP HP, Raymond Poincare Hospital, University Versailles Saint Quentin en Yvelines, 104 Bd Raymond Poincaré, Garches F 92380, France
    Crit Care 15:R47. 2011
    ..The aim of this study was to determine the relationship between hormonal status and mortality in patients with protracted critical illness...
  3. pmc Hyperglycaemia and apoptosis of microglial cells in human septic shock
    Andrea Polito
    General Intensive Care Medicine, Raymond Poincare Hospital, University of Versailles Saint Quentin en Yvelines, 104 Boulevard R Poincaré, Garches, France
    Crit Care 15:R131. 2011
    ..The effect of hyperglycaemia on the brain cells of septic shock patients is unknown. The objective of this study was to evaluate the relationship between hyperglycaemia and apoptosis in the brains of septic shock patients...
  4. doi request reprint Neurologic critical care. Preface
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurol Clin 26:xiii-xv. 2008
  5. ncbi request reprint Coma, delirium, and cognitive dysfunction in critical illness
    Robert D Stevens
    Department of Anesthesiology, Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Crit Care Clin 22:787-804; abstract x. 2006
    ....
  6. doi request reprint Brain imaging in intensive care medicine
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Semin Neurol 28:631-44. 2008
    ..We review some of the established and emerging structural and physiological imaging methods, and discuss their applications in patients with critical injuries including trauma and encephalopathy due to anoxia, liver failure, and sepsis...
  7. ncbi request reprint The role of mechanical ventilation in acute brain injury
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Neurol Clin 26:543-63, x. 2008
    ..Recent research has begun to clarify key questions regarding the pathophysiology and management of MV in critically ill neurological patients...
  8. ncbi request reprint The systemic implications of aneurysmal subarachnoid hemorrhage
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurol Sci 261:143-56. 2007
    ..Interventions to avert or reverse these and other perturbations need to be tested in clinical trials as they represent opportunities to improve survival and neurological recovery in patients with SAH...
  9. ncbi request reprint Neuromuscular dysfunction acquired in critical illness: a systematic review
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 8 140, Baltimore, MD 21287, USA
    Intensive Care Med 33:1876-91. 2007
    ..To determine the prevalence, risk factors, and outcomes of critical illness neuromuscular abnormalities (CINMA)...
  10. ncbi request reprint Types of brain dysfunction in critical illness
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurol Clin 26:469-86, ix. 2008
    ..Although progress has been made in characterizing the epidemiology of cerebral dysfunction in the ICU, more research is needed to elucidate underlying mechanisms that might represent targets for therapeutic intervention...
  11. doi request reprint Intensive care of aneurysmal subarachnoid hemorrhage: an international survey
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Intensive Care Med 35:1556-66. 2009
    ..Patients with aneurysmal subarachnoid hemorrhage (SAH) are routinely admitted to the intensive care unit for the management of neurological and systemic complications...
  12. pmc Weakness in the ICU: a call to action
    Robert D Stevens
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Crit Care 13:1002. 2009
    ..Although preliminary, these results, together with other recent studies, indicate a paradigm shift to a proactive approach in managing neuromuscular complications in the ICU...
  13. doi request reprint A framework for diagnosing and classifying intensive care unit-acquired weakness
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 37:S299-308. 2009
    ..We propose a simple framework for diagnosing and classifying neuromuscular disorders acquired in critical illness...
  14. pmc Delirium in the ICU: time to probe the hard questions
    Robert D Stevens
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N, Wolfe Street, Baltimore, MD 21287, USA
    Crit Care 15:118. 2011
    ..While such epidemiological accounts represent an important cornerstone for research, scientific efforts are needed to elucidate the causes of delirium and the mechanisms underlying its association with poor outcomes...
  15. ncbi request reprint Strategies in the high-risk cardiac patient undergoing non-cardiac surgery
    Robert D Stevens
    Department of Anesthesia and Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St Meter 8 140, Baltimore, MD 21287, USA
    Best Pract Res Clin Anaesthesiol 18:549-63. 2004
    ....
  16. ncbi request reprint Critical care and perioperative management in traumatic spinal cord injury
    Robert D Stevens
    Neurosciences Critical Care Division, Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurosurg Anesthesiol 15:215-29. 2003
    ..Clinical trials of pharmacologic neuroprotection have yielded disappointing results, but the ongoing elucidation of spinal cord repair and regenerative mechanisms suggests new therapeutic prospects...
  17. ncbi request reprint Acute lung injury in critical neurological illness
    Robert E Hoesch
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 40:587-93. 2012
    ..Our aim was to identify risk factors for acute lung injury/acute respiratory distress syndrome in this population...
  18. ncbi request reprint Significance of triphasic waves in patients with acute encephalopathy: a nine-year cohort study
    Raoul Sutter
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin Neurophysiol 124:1952-8. 2013
    ..The aim of this study was to determine the clinical and EEG characteristics in encephalopathic patients with TWs. We hypothesized that specific EEG characteristics are predictive of outcome...
  19. doi request reprint Continuous electroencephalographic monitoring in critically ill patients: indications, limitations, and strategies
    Raoul Sutter
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 41:1124-32. 2013
    ..This review compiles the indications, limitations, and strategies for continuous electroencephalography in the ICU...
  20. pmc Management of brain injury after resuscitation from cardiac arrest
    Romergryko G Geocadin
    Neurosciences Critical Care Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Neurol Clin 26:487-506, ix. 2008
    ....
  21. doi request reprint Clinical and imaging correlates of EEG patterns in hospitalized patients with encephalopathy
    Raoul Sutter
    Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine and Bayview Medical Center, 301 Mason Lord Drive, Suite 2100, Baltimore, MD 21224, USA
    J Neurol 260:1087-98. 2013
    ....
  22. ncbi request reprint Controversies in the management of aneurysmal subarachnoid hemorrhage
    Neeraj S Naval
    Division of Neurosciences Critical Care, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 34:511-24. 2006
    ..Although it is believed that these advances have contributed to improved outcomes, considerable uncertainty persists regarding key areas of management...
  23. ncbi request reprint The spectrum of encephalopathy in critical illness
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Semin Neurol 26:440-51. 2006
    ..The pathogenesis and natural history of encephalopathy, still poorly understood, need further clarification to spur the development of effective preventive and therapeutic interventions...
  24. pmc Functional recovery after moderate/severe traumatic brain injury: a role for cognitive reserve?
    Eric B Schneider
    From the Center for Surgical Trials and Outcomes Research, Department of Surgery E B S, D T E, X H, S Selvarajah, H L H, Division of Neurosciences Critical Care, Departments of Anesthesiology and Critical Care Medicine R G K, R D S, and Departments of Neurology R D S and Neurosurgery R D S, Johns Hopkins School of Medicine, Baltimore, MD Tulane Center for Aging S Sur, Tulane University School of Medicine, New Orleans, LA Department of Radiology V R, J D, R D S, Johns Hopkins University, Baltimore, MD and Centre for Mental Health V R, Department of Medicine, Imperial College London, UK
    Neurology 82:1636-42. 2014
    ..To evaluate the hypothesis that educational attainment, a marker of cognitive reserve, is a predictor of disability-free recovery (DFR) after moderate to severe traumatic brain injury (TBI)...
  25. doi request reprint Mechanisms of neurologic failure in critical illness
    Aliaksei Pustavoitau
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Crit Care Clin 24:1-24, vii. 2008
    ..This article provides an overview of research evaluating the relationship between critical illness and neurologic function, with a special emphasis on underlying mechanisms...
  26. ncbi request reprint Approach to the comatose patient
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, Neurology and Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 34:31-41. 2006
    ..Coma is a medical emergency and may constitute a diagnostic and therapeutic challenge for the intensivist...
  27. ncbi request reprint B-type natriuretic peptide as a marker for heart failure in patients with acute stroke
    Matthew A Koenig
    Johns Hopkins Hospital, Division of Neurosciences Critical Care, 600 N Wolfe Street, Meyer 8 140, Baltimore, MD 21287, USA
    Intensive Care Med 33:1587-93. 2007
    ..To determine whether serum N-terminal pro-B-type natriuretic peptide (N-BNP), a biomarker of myocardial wall stress, is specific to acute heart failure (HF) in patients hospitalized with stroke...
  28. ncbi request reprint Prospective evaluation of pain and analgesic use following major elective intracranial surgery
    Allan Gottschalk
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 4965, USA
    J Neurosurg 106:210-6. 2007
    ..The authors conducted a prospective study to evaluate the incidence, severity, and treatment of postoperative pain in patients who underwent major intracranial surgery...
  29. ncbi request reprint Efficacy of intravenous patient-controlled analgesia after supratentorial intracranial surgery: a prospective randomized controlled trial. Clinical article
    Athir H Morad
    Department of Anesthesiology and Critical Care Medicine, Meyer 8 134, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, Maryland 21287 4965, USA
    J Neurosurg 111:343-50. 2009
    ..The authors hypothesized that intravenous patient-controlled analgesia (PCA) would safely and more effectively treat postoperative supratentorial craniotomy pain than conventional as needed (PRN) therapy...
  30. doi request reprint Neurologic injury and mechanical ventilation
    Paul Nyquist
    Division of Neurosciences Critical Care, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurocrit Care 9:400-8. 2008
    ..We will examine the consequences of ventilator management as they relate to parameters that affect ICP and brain oxygenation in patients who have neurologic injury...
  31. ncbi request reprint Intensive care for brain injury after cardiac arrest: therapeutic hypothermia and related neuroprotective strategies
    Romergryko G Geocadin
    Department of Neurology, Johns Hopkins School of Medicine, Meyer 8 140, Baltimore, MD 21287, USA
    Crit Care Clin 22:619-36; abstract viii. 2006
    ..This article discusses these advances and their potential impact on the care provided in the ICU...
  32. doi request reprint Neurological complications in critical illness: a focus on mechanisms. Preface
    Robert D Stevens
    Johns Hopkins University School of Medicine, Division of Neurosciences Critical Care, Baltimore, MD 21287, USA
    Crit Care Clin 24:xv-xvii. 2008
  33. doi request reprint White matter changes in comatose survivors of anoxic ischemic encephalopathy and traumatic brain injury: comparative diffusion-tensor imaging study
    Anke W van der Eerden
    From the Department of Neuroradiology A W v d E, D D, D G, the Neurosurgical ICU P S, L P, and the Medical ICU C E L, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France Departments of Radiology A W v d E and Neurology P E V, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands INSERM, UMRS 678, Universite Pierre et Marie Curie Paris 6, Paris, France V P, H B Department of Radiology, Massachusetts General Hospital, Boston, Mass O K, J D, R G Division of Neuroscience Critical Care, Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Md R D S Department of Neuroradiology, Guy de Chauliac Hospital, Montpellier, France N M d C Department of Neuroradiology, Roger Salengro Hospital, Lille, France C D Department of Neuroradiology, Centre Hospitalier Universitaire, Rouen, France E T and Cyclotron Research Center, University of Liege
    Radiology 270:506-16. 2014
    ..To analyze white matter pathologic abnormalities by using diffusion-tensor (DT) imaging in a multicenter prospective cohort of comatose patients following cardiac arrest or traumatic brain injury (TBI)...
  34. doi request reprint Imaging brain trauma
    Josh L Duckworth
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Curr Opin Crit Care 16:92-7. 2010
    ..We review recent advances in neuroimaging and discuss how they are helping to address these fundamental gaps...
  35. ncbi request reprint Coma emergence and recovery: The new and the old
    Robert D Stevens
    Departments of Anesthesiology, and Critical Care Medicine, Department of Neurology, Department of Neurosurgery, Department of Radiology, University School of Medicine, Baltimore, MD Departments of Anesthesiology, and Critical Care Medicine, Department of Neurology, Department of Neurosurgery, Johns Hopkins University School, of Medicine, Baltimore, MD
    Crit Care Med 40:1352-3. 2012
  36. ncbi request reprint Emergency neurological life support: intracranial hypertension and herniation
    Robert D Stevens
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neurocrit Care 17:S60-5. 2012
    ..Because there are multiple etiologies and many treatments that can potentially reverse cerebral herniation, intracranial hypertension and herniation was chosen as an Emergency Neurological Life Support (ENLS) protocol...
  37. ncbi request reprint Glucocorticoid therapy in neurologic critical care
    Joao A Gomes
    Neurosciences Critical Care Division, Department of Anesthesia and Critical Care Medicine, Neurology, and Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 33:1214-24. 2005
    ..The pivotal role of inflammation and edema across the spectrum of central nervous system injury has driven extensive investigation into the therapeutic potential of glucocorticoids...
  38. ncbi request reprint Spurious hypoxemia
    Abhijit V Lele
    Neurosciences Critical Care Division, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 33:1854-6. 2005
    ..To discuss the pathophysiology and clinical implications of spurious hypoxemia in the setting of hyperleukocytosis...
  39. ncbi request reprint Pharmacologic myocardial protection in patients undergoing noncardiac surgery: a quantitative systematic review
    Robert D Stevens
    Division of Anesthesiology, Department APSIC, Geneva University Hospitals, Switzerland
    Anesth Analg 97:623-33. 2003
    ..The most common adverse effect was bradycardia, which occurred in 24.5% of patients receiving a beta adrenergic blocker versus 9.1% of controls (OR 3.76 [95% CI, 2.45-5.77], NNH 6)...
  40. ncbi request reprint Evolving paradigms in the management of severe traumatic brain injury
    Robert D Stevens
    Crit Care Med 33:2415-7. 2005
  41. ncbi request reprint Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics
    Christine E Marx
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27705, USA
    Neuropsychopharmacology 31:1249-63. 2006
    ..Neuroactive steroids may therefore be candidate modulators of the pathophysiology of schizophrenia and bipolar disorder, and relevant to the treatment of these disorders...
  42. ncbi request reprint Analysis of a glucose tetrasaccharide elevated in Pompe disease by stable isotope dilution-electrospray ionization tandem mass spectrometry
    Sarah P Young
    Biochemical Genetics Laboratory, Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, P O Box 14991, 99 TW Alexander Drive, Research Triangle Park, NC 27709, USA
    Anal Biochem 316:175-80. 2003
    ..Accurate determination from dried urine spot samples was also demonstrated. This method is amenable to high-throughput analysis, a necessary prerequisite for mass screening for GSD II...
  43. ncbi request reprint The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease
    Christine E Marx
    Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Durham, North Carolina 27705, USA
    Biol Psychiatry 60:1287-94. 2006
    ..We therefore investigated prefrontal cortex (PFC) NS levels in AD...
  44. doi request reprint Eryrthropoietin and the promise of ischemic multiorgan protection
    Robert D Stevens
    Crit Care Med 36:2446-7. 2008