Research Topics
| Lisa A SpacekSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteriaDavid Meya
Infectious Diseases Institute, Makerere University, Kampala, Uganda
J Int AIDS Soc 12:3. 2009..abstract:..- Diagnostic accuracy of ultrasensitive heat-denatured HIV-1 p24 antigen in non-B subtypes in Kampala, UgandaL A Spacek
Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Int J STD AIDS 22:310-4. 2011..Moreover, the Up24 was positive in 33% of samples deemed undetectable by RT-PCR, which may limit the use of the Up24 to detect viral suppression... - Clinical illness as a marker for initiation of HIV antiretroviral therapy in a rural setting, Rakai, UgandaLisa A Spacek
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Int J STD AIDS 17:116-20. 2006..6%; P = 0.001).HIV-related illness and WHO stage predicted disease progression. The specificity of clinical illness to predict viral load >55,000 copies/mL was high and could be used to rule in HIV disease requiring ART... - Response to antiretroviral therapy in HIV-infected patients attending a public, urban clinic in Kampala, UgandaLisa A Spacek
Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Clin Infect Dis 42:252-9. 2006..We evaluated clinical, behavioral, and demographic risk factors associated with virologic suppression in a public, urban clinic in Kampala, Uganda... - Shiga toxin-producing Escherichia coli as a possible etiological agent of chronic diarrheaLisa A Spacek
Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
Clin Infect Dis 39:e46-8. 2004..Both were treated with antibiotics, and neither developed systemic complications of the infection. These cases suggest that STEC infection should be considered in the differential diagnosis of chronic diarrhea... - Total lymphocyte count and hemoglobin combined in an algorithm to initiate the use of highly active antiretroviral therapy in resource-limited settingsLisa A Spacek
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
AIDS 17:1311-7. 2003..To develop clinical algorithms that improve the sensitivity of surrogate markers to initiate the use of highly active antiretroviral therapy (HAART) in resource-limited settings... - Evaluation of a low-cost method, the Guava EasyCD4 assay, to enumerate CD4-positive lymphocyte counts in HIV-infected patients in the United States and UgandaLisa A Spacek
School of Medicine, Johns Hopkins Medical Institutions, Rm 456, 1830 East Monument Street, Baltimore, MD 21287, USA
J Acquir Immune Defic Syndr 41:607-10. 2006..To evaluate the EasyCD4 assay, a less expensive method to enumerate CD4+ lymphocytes, in resource-limited settings... - Total lymphocyte count of 1200 is not a sensitive predictor of CD4 lymphocyte count among patients with HIV disease in Kampala, UgandaMoses R Kamya
Makerere University Medical School, Kampala, Uganda
Afr Health Sci 4:94-101. 2004..Access to HAART is expanding in Kampala, Uganda, yet there are no published data evaluating the utility of TLC as inexpensive surrogate marker of CD4 cell count to help guide therapeutic decisions... - Predictors of long-term viral failure among ugandan children and adults treated with antiretroviral therapyMoses R Kamya
Department of Medicine, Makerere University, Kampala, Uganda
J Acquir Immune Defic Syndr 46:187-93. 2007..We identified predictors of viral failure and documented genotypic mutations in a subset of patients with viral failure after 12 months on antiretroviral therapy (ART)... - Evaluation of Dynabeads and Cytospheres compared with flow cytometry to enumerate CD4+ T cells in HIV-infected Ugandans on antiretroviral therapyFred Lutwama
Academic Alliance for AIDS Care and Prevention and the Infectious Diseases Institute, Kampala, Uganda
J Acquir Immune Defic Syndr 48:297-303. 2008..The World Health Organization 2006 guidelines support the use of CD4 lymphocyte count (CD4) to define treatment failure in resource-limited settings... - WHO draft guidelines for antiretroviral therapy in resource limited settingsLisa A Spacek
Hopkins HIV Rep 14:1, 3-4. 2002
Research Grants
- Clinical Algorithms to Monitor HIV Treatment in UgandaLisa Spacek; Fiscal Year: 2007..Richard Moore and HIV laboratory science with Dr. Thomas Quinn. My long-term goal is to become an independent investigator of HIV clinical epidemiology in resource-limited settings. ..