Lisa A Spacek

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria
    David Meya
    Infectious Diseases Institute, Makerere University, Kampala, Uganda
    J Int AIDS Soc 12:3. 2009
  2. pmc Diagnostic accuracy of ultrasensitive heat-denatured HIV-1 p24 antigen in non-B subtypes in Kampala, Uganda
    L A Spacek
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Int J STD AIDS 22:310-4. 2011
  3. ncbi request reprint Clinical illness as a marker for initiation of HIV antiretroviral therapy in a rural setting, Rakai, Uganda
    Lisa A Spacek
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Int J STD AIDS 17:116-20. 2006
  4. ncbi request reprint Response to antiretroviral therapy in HIV-infected patients attending a public, urban clinic in Kampala, Uganda
    Lisa A Spacek
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Clin Infect Dis 42:252-9. 2006
  5. ncbi request reprint Shiga toxin-producing Escherichia coli as a possible etiological agent of chronic diarrhea
    Lisa A Spacek
    Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Clin Infect Dis 39:e46-8. 2004
  6. ncbi request reprint Total lymphocyte count and hemoglobin combined in an algorithm to initiate the use of highly active antiretroviral therapy in resource-limited settings
    Lisa A Spacek
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    AIDS 17:1311-7. 2003
  7. ncbi request reprint Evaluation of a low-cost method, the Guava EasyCD4 assay, to enumerate CD4-positive lymphocyte counts in HIV-infected patients in the United States and Uganda
    Lisa A Spacek
    School of Medicine, Johns Hopkins Medical Institutions, Rm 456, 1830 East Monument Street, Baltimore, MD 21287, USA
    J Acquir Immune Defic Syndr 41:607-10. 2006
  8. pmc Total lymphocyte count of 1200 is not a sensitive predictor of CD4 lymphocyte count among patients with HIV disease in Kampala, Uganda
    Moses R Kamya
    Makerere University Medical School, Kampala, Uganda
    Afr Health Sci 4:94-101. 2004
  9. ncbi request reprint Predictors of long-term viral failure among ugandan children and adults treated with antiretroviral therapy
    Moses R Kamya
    Department of Medicine, Makerere University, Kampala, Uganda
    J Acquir Immune Defic Syndr 46:187-93. 2007
  10. pmc Evaluation of Dynabeads and Cytospheres compared with flow cytometry to enumerate CD4+ T cells in HIV-infected Ugandans on antiretroviral therapy
    Fred Lutwama
    Academic Alliance for AIDS Care and Prevention and the Infectious Diseases Institute, Kampala, Uganda
    J Acquir Immune Defic Syndr 48:297-303. 2008

Research Grants

Collaborators

Detail Information

Publications11

  1. pmc Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria
    David Meya
    Infectious Diseases Institute, Makerere University, Kampala, Uganda
    J Int AIDS Soc 12:3. 2009
    ..abstract:..
  2. pmc Diagnostic accuracy of ultrasensitive heat-denatured HIV-1 p24 antigen in non-B subtypes in Kampala, Uganda
    L A Spacek
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Int J STD AIDS 22:310-4. 2011
    ..Moreover, the Up24 was positive in 33% of samples deemed undetectable by RT-PCR, which may limit the use of the Up24 to detect viral suppression...
  3. ncbi request reprint Clinical illness as a marker for initiation of HIV antiretroviral therapy in a rural setting, Rakai, Uganda
    Lisa A Spacek
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Int J STD AIDS 17:116-20. 2006
    ..6%; P = 0.001).HIV-related illness and WHO stage predicted disease progression. The specificity of clinical illness to predict viral load >55,000 copies/mL was high and could be used to rule in HIV disease requiring ART...
  4. ncbi request reprint Response to antiretroviral therapy in HIV-infected patients attending a public, urban clinic in Kampala, Uganda
    Lisa A Spacek
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Clin Infect Dis 42:252-9. 2006
    ..We evaluated clinical, behavioral, and demographic risk factors associated with virologic suppression in a public, urban clinic in Kampala, Uganda...
  5. ncbi request reprint Shiga toxin-producing Escherichia coli as a possible etiological agent of chronic diarrhea
    Lisa A Spacek
    Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Clin Infect Dis 39:e46-8. 2004
    ..Both were treated with antibiotics, and neither developed systemic complications of the infection. These cases suggest that STEC infection should be considered in the differential diagnosis of chronic diarrhea...
  6. ncbi request reprint Total lymphocyte count and hemoglobin combined in an algorithm to initiate the use of highly active antiretroviral therapy in resource-limited settings
    Lisa A Spacek
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    AIDS 17:1311-7. 2003
    ..To develop clinical algorithms that improve the sensitivity of surrogate markers to initiate the use of highly active antiretroviral therapy (HAART) in resource-limited settings...
  7. ncbi request reprint Evaluation of a low-cost method, the Guava EasyCD4 assay, to enumerate CD4-positive lymphocyte counts in HIV-infected patients in the United States and Uganda
    Lisa A Spacek
    School of Medicine, Johns Hopkins Medical Institutions, Rm 456, 1830 East Monument Street, Baltimore, MD 21287, USA
    J Acquir Immune Defic Syndr 41:607-10. 2006
    ..To evaluate the EasyCD4 assay, a less expensive method to enumerate CD4+ lymphocytes, in resource-limited settings...
  8. pmc Total lymphocyte count of 1200 is not a sensitive predictor of CD4 lymphocyte count among patients with HIV disease in Kampala, Uganda
    Moses R Kamya
    Makerere University Medical School, Kampala, Uganda
    Afr Health Sci 4:94-101. 2004
    ..Access to HAART is expanding in Kampala, Uganda, yet there are no published data evaluating the utility of TLC as inexpensive surrogate marker of CD4 cell count to help guide therapeutic decisions...
  9. ncbi request reprint Predictors of long-term viral failure among ugandan children and adults treated with antiretroviral therapy
    Moses R Kamya
    Department of Medicine, Makerere University, Kampala, Uganda
    J Acquir Immune Defic Syndr 46:187-93. 2007
    ..We identified predictors of viral failure and documented genotypic mutations in a subset of patients with viral failure after 12 months on antiretroviral therapy (ART)...
  10. pmc Evaluation of Dynabeads and Cytospheres compared with flow cytometry to enumerate CD4+ T cells in HIV-infected Ugandans on antiretroviral therapy
    Fred Lutwama
    Academic Alliance for AIDS Care and Prevention and the Infectious Diseases Institute, Kampala, Uganda
    J Acquir Immune Defic Syndr 48:297-303. 2008
    ..The World Health Organization 2006 guidelines support the use of CD4 lymphocyte count (CD4) to define treatment failure in resource-limited settings...
  11. ncbi request reprint WHO draft guidelines for antiretroviral therapy in resource limited settings
    Lisa A Spacek
    Hopkins HIV Rep 14:1, 3-4. 2002

Research Grants2

  1. Clinical Algorithms to Monitor HIV Treatment in Uganda
    Lisa Spacek; Fiscal Year: 2007
    ..Richard Moore and HIV laboratory science with Dr. Thomas Quinn. My long-term goal is to become an independent investigator of HIV clinical epidemiology in resource-limited settings. ..