Gwenn Smith

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Increased cerebral metabolism after 1 year of deep brain stimulation in Alzheimer disease
    Gwenn S Smith
    Division of Geriatric Psychiatry and Neuropsychiatry, The Johns Hopkins University School of Medicine, The Johns Hopkins Bayview Medical Center, 5300 Alpha Commons Dr, 4th Floor, Baltimore, MD 21224, USA
    Arch Neurol 69:1141-8. 2012
  2. ncbi Serotonin transporter occupancy and the functional neuroanatomic effects of citalopram in geriatric depression
    Gwenn S Smith
    Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Am J Geriatr Psychiatry 19:1016-25. 2011
  3. ncbi The relationship between the acute cerebral metabolic response to citalopram and chronic citalopram treatment outcome
    Gwenn S Smith
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Am J Geriatr Psychiatry 19:53-63. 2011
  4. ncbi Serotonin modulation of cerebral glucose metabolism in depressed older adults
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Biol Psychiatry 66:259-66. 2009
  5. ncbi The functional neuroanatomy of geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Int J Geriatr Psychiatry 24:798-808. 2009
  6. ncbi Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Brain 132:392-401. 2009
  7. ncbi Effects of serotonin transporter promoter polymorphisms on serotonin function
    Gwenn S Smith
    Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 29:2226-34. 2004
  8. ncbi Serotonin modulation of cerebral glucose metabolism in normal aging
    Sara Goldberg
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, 75-59 263rd Street, Glen Oaks, NY 11004, USA
    Neurobiol Aging 25:167-74. 2004
  9. ncbi Serotonin modulation of cerebral glucose metabolism measured with positron emission tomography (PET) in human subjects
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital, Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 45:105-12. 2002
  10. ncbi Cerebral glucose metabolic response to combined total sleep deprivation and antidepressant treatment in geriatric depression: a randomized, placebo-controlled study
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Psychiatry Res 171:1-9. 2009

Research Grants

  1. Serotonin Modulation in Geriatric Depression
    Gwenn Smith; Fiscal Year: 2006
  2. Geriatric Depression: PET Studies of Pathophysiology and Treatment Response
    Gwenn S Smith; Fiscal Year: 2010

Detail Information

Publications15

  1. ncbi Increased cerebral metabolism after 1 year of deep brain stimulation in Alzheimer disease
    Gwenn S Smith
    Division of Geriatric Psychiatry and Neuropsychiatry, The Johns Hopkins University School of Medicine, The Johns Hopkins Bayview Medical Center, 5300 Alpha Commons Dr, 4th Floor, Baltimore, MD 21224, USA
    Arch Neurol 69:1141-8. 2012
    ....
  2. ncbi Serotonin transporter occupancy and the functional neuroanatomic effects of citalopram in geriatric depression
    Gwenn S Smith
    Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Am J Geriatr Psychiatry 19:1016-25. 2011
    ..The functional neuroanatomic changes associated with selective serotonin reuptake inhibitor (SSRI) treatment have been the focus of positron emission tomography (PET) studies of cerebral glucose metabolism in geriatric depression...
  3. ncbi The relationship between the acute cerebral metabolic response to citalopram and chronic citalopram treatment outcome
    Gwenn S Smith
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Am J Geriatr Psychiatry 19:53-63. 2011
    ....
  4. ncbi Serotonin modulation of cerebral glucose metabolism in depressed older adults
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Biol Psychiatry 66:259-66. 2009
    ..The hypothesis was tested that smaller decreases in metabolism would be observed in cortical and limbic regions in depressed older adults relative to control subjects...
  5. ncbi The functional neuroanatomy of geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Int J Geriatr Psychiatry 24:798-808. 2009
    ....
  6. ncbi Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Brain 132:392-401. 2009
    ..The combined cerebral metabolic effects of galantamine and citalopram suggest, consistent with preclinical data, a synergistic interaction of cholinergic and serotonergic systems...
  7. ncbi Effects of serotonin transporter promoter polymorphisms on serotonin function
    Gwenn S Smith
    Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 29:2226-34. 2004
    ....
  8. ncbi Serotonin modulation of cerebral glucose metabolism in normal aging
    Sara Goldberg
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, 75-59 263rd Street, Glen Oaks, NY 11004, USA
    Neurobiol Aging 25:167-74. 2004
    ..These results suggest different compensatory processes in anterior compared to posterior brain regions secondary to the age-related loss of serotonin innervation...
  9. ncbi Serotonin modulation of cerebral glucose metabolism measured with positron emission tomography (PET) in human subjects
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital, Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 45:105-12. 2002
    ..Future studies will evaluate how the acute metabolic response to citalopram relates to the metabolic response after chronic treatment in patients with geriatric depression...
  10. ncbi Cerebral glucose metabolic response to combined total sleep deprivation and antidepressant treatment in geriatric depression: a randomized, placebo-controlled study
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Psychiatry Res 171:1-9. 2009
    ....
  11. ncbi Cerebral glucose metabolism and D2/D3 receptor availability in young adults with cannabis dependence measured with positron emission tomography
    Serge Sevy
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, NY 11004, USA
    Psychopharmacology (Berl) 197:549-56. 2008
    ....
  12. ncbi Acute and chronic effects of citalopram on cerebral glucose metabolism in geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital and the Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Geriatr Psychiatry 10:715-23. 2002
    ....
  13. ncbi Selective serotonin reuptake inhibitor (SSRI) modulation of striatal dopamine measured with [11C]-raclopride and positron emission tomography
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 63:1-6. 2009
    ....
  14. ncbi Applications of neuroreceptor imaging to psychiatry research
    Gwenn S Smith
    Department of Psychiatry Research, Zucker Hillside Hospital of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychopharmacol Bull 37:26-65. 2003
    ..These data will provide important insights into the neurochemical substrates of treatment response variability in psychiatric disorders that will have important implications for the refinement of pharmacotherapy...
  15. ncbi Glucose metabolic response to total sleep deprivation, recovery sleep, and acute antidepressant treatment as functional neuroanatomic correlates of treatment outcome in geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital of the North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Am J Geriatr Psychiatry 10:561-7. 2002
    ....

Research Grants7

  1. Serotonin Modulation in Geriatric Depression
    Gwenn Smith; Fiscal Year: 2006
    ..abstract_text> ..
  2. Geriatric Depression: PET Studies of Pathophysiology and Treatment Response
    Gwenn S Smith; Fiscal Year: 2010
    ..We will test the hypotheses that patients who do not respond as well to treatment have less serotonin in their brains and greater beta-amyloid protein. ..