Sonal Singh

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Drug safety assessment in clinical trials: methodological challenges and opportunities
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Trials 13:138. 2012
  2. ncbi Chapter 7: grading a body of evidence on diagnostic tests
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, 624 N Broadway, Baltimore, MD 21205, USA
    J Gen Intern Med 27:S47-55. 2012
  3. ncbi Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    CMAJ 183:1359-66. 2011
  4. ncbi Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD 21287, USA
    BMJ 342:d3215. 2011
  5. ncbi Long-term use of thiazolidinediones and the associated risk of pneumonia or lower respiratory tract infection: systematic review and meta-analysis
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, 1830 E Monument St, Suite 8063, Baltimore, MD 21287, USA
    Thorax 66:383-8. 2011
  6. ncbi An overview of the benefits and drawbacks of inhaled corticosteroids in chronic obstructive pulmonary disease
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Int J Chron Obstruct Pulmon Dis 5:189-95. 2010
  7. ncbi Risk of pneumonia associated with long-term use of inhaled corticosteroids in chronic obstructive pulmonary disease: a critical review and update
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Curr Opin Pulm Med 16:118-22. 2010
  8. ncbi Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
    Sonal Singh
    Department of Medicine, One Medical Center Blvd, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 300:1439-50. 2008
  9. ncbi Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease: a meta-analysis
    Sonal Singh
    Department of Medicine, Wake Forest University School of Medicine, One Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Intern Med 169:219-29. 2009
  10. ncbi Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 1901, USA
    Thorax 68:114-6. 2013

Detail Information

Publications16

  1. ncbi Drug safety assessment in clinical trials: methodological challenges and opportunities
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Trials 13:138. 2012
    ..Regulatory and academic partnerships should be fostered to provide an independent and transparent evaluation of drug safety...
  2. ncbi Chapter 7: grading a body of evidence on diagnostic tests
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, 624 N Broadway, Baltimore, MD 21205, USA
    J Gen Intern Med 27:S47-55. 2012
    ..However if reviewers choose to combine domains into a single grade of evidence, they should explain their rationale for a particular summary grade and the relevant domains that were weighed in assigning the summary grade...
  3. ncbi Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    CMAJ 183:1359-66. 2011
    ..We conducted a systematic review and meta-analysis of randomized controlled trials to ascertain the serious adverse cardiovascular effects of varenicline compared with placebo among tobacco users...
  4. ncbi Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD 21287, USA
    BMJ 342:d3215. 2011
    ..To systematically review the risk of mortality associated with long term use of tiotropium delivered using a mist inhaler for symptomatic improvement in chronic obstructive pulmonary disease...
  5. ncbi Long-term use of thiazolidinediones and the associated risk of pneumonia or lower respiratory tract infection: systematic review and meta-analysis
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, 1830 E Monument St, Suite 8063, Baltimore, MD 21287, USA
    Thorax 66:383-8. 2011
    ..The authors aimed to systematically determine the risk of pneumonia or lower respiratory tract infections associated with thiazolidinediones...
  6. ncbi An overview of the benefits and drawbacks of inhaled corticosteroids in chronic obstructive pulmonary disease
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Int J Chron Obstruct Pulmon Dis 5:189-95. 2010
    ..The benefit harm profile of inhaled corticosteroids, and their effect on patient oriented outcomes and comorbid pneumonia, osteoporosis and cardiovascular disease in patients with chronic obstructive pulmonary disease remain uncertain...
  7. ncbi Risk of pneumonia associated with long-term use of inhaled corticosteroids in chronic obstructive pulmonary disease: a critical review and update
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Curr Opin Pulm Med 16:118-22. 2010
    ....
  8. ncbi Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
    Sonal Singh
    Department of Medicine, One Medical Center Blvd, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 300:1439-50. 2008
    ..Inhaled anticholinergics (ipratropium bromide or tiotropium bromide) are widely used in patients with chronic obstructive pulmonary disease (COPD) but their effect on the risk of cardiovascular outcomes is unknown...
  9. ncbi Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease: a meta-analysis
    Sonal Singh
    Department of Medicine, Wake Forest University School of Medicine, One Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Intern Med 169:219-29. 2009
    ..We aimed to ascertain the risk of pneumonia with long-term inhaled corticosteroid use among patients with chronic obstructive pulmonary disease (COPD)...
  10. ncbi Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications
    Sonal Singh
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 1901, USA
    Thorax 68:114-6. 2013
    ..The authors urge caution in prescribing inhaled anticholinergics for patients with pre-existing arrhythmias or cardiac disorders...
  11. ncbi The safety of rosiglitazone in the treatment of type 2 diabetes
    Sonal Singh
    Wake Forest University School of Medicine, Department of Medicine, Winston Salem, NC 27103, USA
    Expert Opin Drug Saf 7:579-85. 2008
    ..The thiazolidinediones including rosiglitazone are approved for the treatment of Type 2 diabetes on the basis of their ability to lower blood sugar and surrogate markers of cardiovascular disease...
  12. ncbi Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis
    Sonal Singh
    Department of Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    JAMA 298:1189-95. 2007
    ..Recent reports of serious adverse events with rosiglitazone use have raised questions about whether the evidence of harm justifies its use for treatment of type 2 diabetes...
  13. ncbi Thromboprophylaxis in cancer patients with central venous catheters. A systematic review and meta-analysis
    Pooja Chaukiyal
    Department of Medicine, Unity Health System, 1555 Long Pond Road, Rochester, NY 14626, USA
    Thromb Haemost 99:38-43. 2008
    ..The use of primary thromboprophylaxis in cancer patients with central venous catheters while not causing any harm provides no benefit...
  14. ncbi Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations
    Wendy L Bennett
    The Johns Hopkins University School of Medicine and The Johns Hopkins Bloomberg School of Public Health, 2024 East Monument Street, Baltimore, MD 21205, USA
    Ann Intern Med 154:602-13. 2011
    ..Given the increase in medications for type 2 diabetes mellitus, clinicians and patients need information about their effectiveness and safety to make informed choices...
  15. ncbi A framework for organizing and selecting quantitative approaches for benefit-harm assessment
    Milo A Puhan
    Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Room E6153, Baltimore, MD 21205, USA
    BMC Med Res Methodol 12:173. 2012
    ..Our aim was to review existing quantitative approaches for benefit-harm assessment and to develop an organizing framework that clarifies differences and aids selection of quantitative approaches for a particular benefit-harm assessment...
  16. ncbi Network meta-analysis-highly attractive but more methodological research is needed
    Tianjing Li
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21212, USA
    BMC Med 9:79. 2011
    ..Since this commentary reflects the discussion at that meeting, it is not intended to provide an overview of the field...