Ellen K Silbergeld

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. pmc Antimicrobial-resistant Bacteria: An Unrecognized Work-related Risk in Food Animal Production
    Ricardo Castillo Neyra
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Saf Health Work 3:85-91. 2012
  2. pmc Mercury induces an unopposed inflammatory response in human peripheral blood mononuclear cells in vitro
    Renee M Gardner
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Environ Health Perspect 117:1932-8. 2009
  3. ncbi request reprint Evidence-based toxicology: strait is the gate, but the road is worth taking
    Ellen Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    ALTEX 30:67-73. 2013
  4. pmc Low level methylmercury exposure affects neuropsychological function in adults
    Edna M Yokoo
    Institute of Social Medicine Universidade Estaduel do Rio de Janeiro, Brazil
    Environ Health 2:8. 2003
  5. ncbi request reprint Mercury and autoimmunity: implications for occupational and environmental health
    Ellen K Silbergeld
    Department of Environmental Health Sciences, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Toxicol Appl Pharmacol 207:282-92. 2005
  6. ncbi request reprint Facilitative mechanisms of lead as a carcinogen
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Mutat Res 533:121-33. 2003
  7. ncbi request reprint Environmental exposures, toxicologic mechanisms, and adverse pregnancy outcomes
    Ellen K Silbergeld
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Obstet Gynecol 192:S11-21. 2005
  8. ncbi request reprint Organizational and activational effects of estrogenic endocrine disrupting chemicals
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Cad Saude Publica 18:495-504. 2002
  9. doi request reprint The environmental and public health risks associated with arsenical use in animal feeds
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1140:346-57. 2008
  10. ncbi request reprint Mercury exposure and malaria prevalence among gold miners in Pará, Brazil
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
    Rev Soc Bras Med Trop 35:421-9. 2002

Detail Information

Publications79

  1. pmc Antimicrobial-resistant Bacteria: An Unrecognized Work-related Risk in Food Animal Production
    Ricardo Castillo Neyra
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Saf Health Work 3:85-91. 2012
    ..These risks are not yet recognized by any work-related health and safety agency in the world...
  2. pmc Mercury induces an unopposed inflammatory response in human peripheral blood mononuclear cells in vitro
    Renee M Gardner
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Environ Health Perspect 117:1932-8. 2009
    ..Dysregulation of cytokine signaling appears to play an important role in the etiology of Hg-induced autoimmunity in animal models...
  3. ncbi request reprint Evidence-based toxicology: strait is the gate, but the road is worth taking
    Ellen Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    ALTEX 30:67-73. 2013
    ..An evidence-based approach does not obviate the role of judgment and values in decision making; its goal is to ensure provision of all available information in a transparent and unbiased manner...
  4. pmc Low level methylmercury exposure affects neuropsychological function in adults
    Edna M Yokoo
    Institute of Social Medicine Universidade Estaduel do Rio de Janeiro, Brazil
    Environ Health 2:8. 2003
    ..The present study reports on the results of neuropsychological testing and hair mercury concentrations in adults (>17 yrs) living in fishing communities of Baixada Cuiabana (Mato Grosso) in the Pantanal region of Brazil...
  5. ncbi request reprint Mercury and autoimmunity: implications for occupational and environmental health
    Ellen K Silbergeld
    Department of Environmental Health Sciences, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Toxicol Appl Pharmacol 207:282-92. 2005
    ..These results suggest a new model for Hg immunotoxicity, as a co-factor in autoimmune disease, increasing the risks and severity of clinical disease in the presence of other triggering events, either genetic or acquired...
  6. ncbi request reprint Facilitative mechanisms of lead as a carcinogen
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Mutat Res 533:121-33. 2003
    ..Some of these events may also be relevant to understanding mechanisms of lead-induced reproductive toxicity...
  7. ncbi request reprint Environmental exposures, toxicologic mechanisms, and adverse pregnancy outcomes
    Ellen K Silbergeld
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Obstet Gynecol 192:S11-21. 2005
    ....
  8. ncbi request reprint Organizational and activational effects of estrogenic endocrine disrupting chemicals
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Cad Saude Publica 18:495-504. 2002
    ....
  9. doi request reprint The environmental and public health risks associated with arsenical use in animal feeds
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1140:346-57. 2008
    ..This continued expansion of arsenical drug use may likely increase the burden of global human arsenic exposure and risk...
  10. ncbi request reprint Mercury exposure and malaria prevalence among gold miners in Pará, Brazil
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
    Rev Soc Bras Med Trop 35:421-9. 2002
    ....
  11. ncbi request reprint Environmental exposures and women's health
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Clin Obstet Gynecol 45:1119-28. 2002
  12. doi request reprint Industrial food animal production, antimicrobial resistance, and human health
    Ellen K Silbergeld
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Annu Rev Public Health 29:151-69. 2008
    ....
  13. ncbi request reprint One reservoir: redefining the community origins of antimicrobial-resistant infections
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, E6644, Baltimore, MD 21205, USA
    Med Clin North Am 92:1391-407, xi. 2008
    ....
  14. ncbi request reprint Commentary: the role of toxicology in prevention and precaution
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21210, USA
    Int J Occup Med Environ Health 17:91-102. 2004
    ..Thus, rather than a "new science", advocates for change should focus upon ensuring that current scientific methods are appropriate and that interpretations of scientific data are accurate...
  15. ncbi request reprint Effect modification by delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase gene polymorphisms on associations between patella lead and renal function in lead workers
    Virginia M Weaver
    Division of Occupational and Environmental Health, Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Environ Res 102:61-9. 2006
    ..In conclusion, VDR and/or ALAD genotypes modified associations between all the lead biomarkers, except patella lead, and the renal outcomes...
  16. ncbi request reprint Associations of patella lead with polymorphisms in the vitamin D receptor, delta-aminolevulinic acid dehydratase and endothelial nitric oxide synthase genes
    Keson Theppeang
    Departments of Environmental Health Sciences, Johns Hopkins School of Medicine and Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Occup Environ Med 46:528-37. 2004
    ..6 microg Pb/g bone mineral) than lead workers with the VDR bb genotype. There was evidence that the relation between age and patella lead was modified by both the VDR and eNOS genotypes...
  17. pmc Associations of uric acid with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers
    Virginia M Weaver
    Division of Occupational and Environmental Health, Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 113:1509-15. 2005
    ..We conclude that genetic polymorphisms may modify uric acid mediation of lead-related adverse renal effects...
  18. ncbi request reprint The G(894)-T(894) polymorphism in the gene for endothelial nitric oxide synthase and blood pressure in lead-exposed workers from Korea
    Mark E Lustberg
    Department of Epidemiology and Preventive Medicine, University of Maryland Baltimore, Baltimore, Maryland 21205, USA
    J Occup Environ Med 46:584-90. 2004
    ..These data provide no evidence that the T allele is associated with higher blood pressure or modifies the association of lead dose with blood pressure...
  19. pmc Mercury exposure, serum antinuclear/antinucleolar antibodies, and serum cytokine levels in mining populations in Amazonian Brazil: a cross-sectional study
    Renee M Gardner
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Baltimore, MD 21205, USA
    Environ Res 110:345-54. 2010
    ..This study provides further evidence that mercury exposure may lead to autoimmune dysfunction and systemic inflammation in affected populations...
  20. pmc Cadmium exposure and incident cardiovascular disease
    Maria Tellez-Plaza
    Department of Epidemiology and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Epidemiology 24:421-9. 2013
    ..We evaluated the association of urine cadmium concentration with cardiovascular disease incidence and mortality in a large population-based cohort...
  21. pmc SLCO1B1 variants and urine arsenic metabolites in the Strong Heart Family Study
    Matthew O Gribble
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205
    Toxicol Sci 136:19-25. 2013
    ..Replication of this finding in other populations and analyses with respect to disease outcomes are needed to determine whether this novel candidate gene is important for arsenic-associated disease risks. ..
  22. pmc Arsenic exposure, diabetes prevalence, and diabetes control in the Strong Heart Study
    Matthew O Gribble
    Departments of Environmental Health Sciences and Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Room W7513D, Baltimore, MD 21205, USA
    Am J Epidemiol 176:865-74. 2012
    ..Prospective studies that evaluate the direction of the relation between poor diabetes control and arsenic exposure are needed...
  23. ncbi request reprint Industrial food animal production and global health risks: exploring the ecosystems and economics of avian influenza
    Jessica H Leibler
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Ecohealth 6:58-70. 2009
    ..In order to more effectively reduce zoonotic disease risk from industrial food animal production, private incentives for the implementation of biosecurity must align with public health interests...
  24. ncbi request reprint Arsenic exposure and prevalence of type 2 diabetes in US adults
    Ana Navas-Acien
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room W7033B, Baltimore, MD 21205, USA
    JAMA 300:814-22. 2008
    ..In contrast, arsenobetaine, an organic arsenic compound derived from seafood intake, is considered nontoxic...
  25. doi request reprint Antibiotic resistant enterococci and staphylococci isolated from flies collected near confined poultry feeding operations
    Jay P Graham
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Division of Environmental Health Engineering, Baltimore, MD 21205, USA
    Sci Total Environ 407:2701-10. 2009
    ..We report that flies collected near broiler poultry operations may be involved in the spread of drug resistant bacteria from these operations and may increase the potential for human exposure to drug resistant bacteria...
  26. ncbi request reprint Confounding of the relation between homocysteine and peripheral arterial disease by lead, cadmium, and renal function
    Eliseo Guallar
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Am J Epidemiol 163:700-8. 2006
    ..The association of lead and cadmium with PAD risk deserves further investigation...
  27. pmc Household risk factors for colonization with multidrug-resistant Staphylococcus aureus isolates
    Meghan F Davis
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    PLoS ONE 8:e54733. 2013
    ..Understanding drivers of antimicrobial resistance in MRSA isolates is important to hospital infection control efforts, relevant to patient outcomes and to indicators of the economic burden of antimicrobial resistance...
  28. doi request reprint Food animal transport: a potential source of community exposures to health hazards from industrial farming (CAFOs)
    Ana M Rule
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Division of Environmental Health Engineering, Baltimore, MD 21205 USA
    J Infect Public Health 1:33-9. 2008
    ..These findings support the need for further exposure characterization, and attention to improving methods of food animal transport, especially in highly trafficked regions of high density farming such as the Delmarva Peninsula...
  29. doi request reprint Bone lead levels and blood pressure endpoints: a meta-analysis
    Ana Navas-Acien
    Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Epidemiology 19:496-504. 2008
    ..We performed a meta-analysis of the association of bone lead levels with systolic blood pressure, diastolic blood pressure, and hypertension using published data...
  30. ncbi request reprint Arsenic exposure and cardiovascular disease: a systematic review of the epidemiologic evidence
    Ana Navas-Acien
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2223, USA
    Am J Epidemiol 162:1037-49. 2005
    ..In other populations or in occupational settings, the evidence was inconclusive. Because of the high prevalence of arsenic exposure, carefully performed studies of arsenic and cardiovascular outcomes should be a research priority...
  31. pmc Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in Amazon populations in Brazil: a cross-sectional study
    Ines A Silva
    The Johns Hopkins University Bloomberg School of Public Health, 615 N, Wolfe Street, Room E6642, Baltimore, Maryland 21201, USA
    Environ Health 3:11. 2004
    ..A few studies have examined relationships between mercury exposures and adverse immunological reactions in humans, but there is little evidence of mercury-associated autoimmunity in humans...
  32. pmc Cadmium levels in urine and mortality among U.S. adults
    Andy Menke
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 117:190-6. 2009
    ..However, studies investigating this association have included participants with considerably higher levels of cadmium than those found in the general population...
  33. pmc Seafood intake and urine concentrations of total arsenic, dimethylarsinate and arsenobetaine in the US population
    Ana Navas-Acien
    Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Environ Res 111:110-8. 2011
    ..Seafood is the main source of organic arsenic exposure (arsenobetaine, arsenosugars and arsenolipids) in the population. Arsenosugars and arsenolipids are metabolized to several species including dimethylarsinate (DMA)...
  34. pmc The animal-human interface and infectious disease in industrial food animal production: rethinking biosecurity and biocontainment
    Jay P Graham
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Division of Environmental Health Engineering, Baltimore, MD 21205, USA
    Public Health Rep 123:282-99. 2008
    ..These data suggest that successful strategies to prevent or mitigate the emergence of pandemic avian influenza must consider risk factors specific to modern industrialized food animal production...
  35. ncbi request reprint Fate of antimicrobial-resistant enterococci and staphylococci and resistance determinants in stored poultry litter
    Jay P Graham
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Environ Res 109:682-9. 2009
    ..This study indicates that typical storage practices of poultry litter are insufficient for eliminating drug-resistant enterococci and staphylococci, which may then be released into the environment through land disposal...
  36. ncbi request reprint Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adults
    Andy Menke
    Department of Epidemiology, Tulane University SPHTM, 1430 Tulane Ave, New Orleans, LA 70112, USA
    Circulation 114:1388-94. 2006
    ..The objective of the present study was to determine the association between blood lead levels below 0.48 micromol/L and mortality in the general US population...
  37. pmc Heritability and preliminary genome-wide linkage analysis of arsenic metabolites in urine
    Maria Tellez-Plaza
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 121:345-51. 2013
    ..Arsenic (III) methyltransferase (AS3MT) has been related to urine arsenic metabolites in association studies. Other genes might also play roles in arsenic metabolism and excretion...
  38. pmc Urine arsenic and prevalent albuminuria: evidence from a population-based study
    Laura Y Zheng
    Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Kidney Dis 61:385-94. 2013
    ..Our objective was to evaluate the cross-sectional association between inorganic arsenic exposure and albuminuria in American Indian adults from rural areas of Arizona, Oklahoma, and North and South Dakota...
  39. pmc Lead exposure and cardiovascular disease--a systematic review
    Ana Navas-Acien
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 115:472-82. 2007
    ..This systematic review evaluates the evidence on the association between lead exposure and cardiovascular end points in human populations...
  40. doi request reprint An ecological perspective on U.S. industrial poultry production: the role of anthropogenic ecosystems on the emergence of drug-resistant bacteria from agricultural environments
    Meghan F Davis
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States
    Curr Opin Microbiol 14:244-50. 2011
    ....
  41. pmc Urine arsenic concentrations and species excretion patterns in American Indian communities over a 10-year period: the Strong Heart Study
    Ana Navas-Acien
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Environ Health Perspect 117:1428-33. 2009
    ..Arsenic exposure in drinking water disproportionately affects small communities in some U.S. regions, including American Indian communities. In U.S. adults with no seafood intake, median total urine arsenic is 3.4 microg/L...
  42. doi request reprint Correlation between animal nasal carriage and environmental methicillin-resistant Staphylococcus aureus isolates at U.S. horse and cattle farms
    Amy E Peterson
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Vet Microbiol 160:539-43. 2012
    ..The methods presented here may aid in surveillance efforts for equine and other animal MRSA. This study successfully applies existing MRSA surveillance methods for indoor, high animal density settings to outdoor and low-density farms...
  43. pmc Fetal and maternal immune responses to methylmercury exposure: a cross-sectional study
    Jennifer F Nyland
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615N Wolfe Street, Baltimore, MD 21205, USA
    Environ Res 111:584-9. 2011
    ..However, unlike previous data from adult males and non-pregnant females, we found no evidence that antinuclear and antinucleolar autoantibody titer is a reliable biomarker of mercury immunotoxicity in this population...
  44. doi request reprint Differential immunotoxic effects of inorganic and organic mercury species in vitro
    Renee M Gardner
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N Wolfe St, Baltimore, MD 21205, United States
    Toxicol Lett 198:182-90. 2010
    ..These results indicate that both organic and inorganic species of Hg can affect the human immune system, but that they may exert different effects on immune function...
  45. pmc Impact of urine concentration adjustment method on associations between urine metals and estimated glomerular filtration rates (eGFR) in adolescents
    Virginia M Weaver
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA Johns Hopkins University School of Medicine, Baltimore, MD, USA Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA Electronic address
    Environ Res 132:226-32. 2014
    ..Additional research using non-creatinine-based methods of adjustment for urine concentration is necessary...
  46. pmc Differential methylation of the arsenic (III) methyltransferase promoter according to arsenic exposure
    Matthew O Gribble
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Arch Toxicol 88:275-82. 2014
    ..These findings may suggest that arsenic exposure influences the epigenetic regulation of a major arsenic metabolism gene. ..
  47. pmc Livestock density as risk factor for livestock-associated methicillin-resistant Staphylococcus aureus, the Netherlands
    Beth J Feingold
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA
    Emerg Infect Dis 18:1841-9. 2012
    ..Controlling the spread of LA-MRSA thus requires giving attention to community members in animal-dense regions who are unaffiliated with livestock farming...
  48. pmc Molecular and phenotypic characteristics of healthcare- and community-associated methicillin-resistant Staphylococcus aureus at a rural hospital
    Amy E Peterson
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
    PLoS ONE 7:e38354. 2012
    ..While methicillin-resistant Staphylococcus aureus (MRSA) originally was associated with healthcare, distinct strains later emerged in patients with no prior hospital contact. The epidemiology of MRSA continues to evolve...
  49. doi request reprint Prevalence of potentially neuropathic Campylobacter jejuni strains on commercial broiler chicken products
    Christopher G Hardy
    Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Int J Food Microbiol 145:395-9. 2011
    ..In terms of cstII polymorphisms, there were also similarities between isolates from poultry and those from patients with GBS and MFS...
  50. pmc Low-level lead exposure and elevations in blood pressure during pregnancy
    Ellen M Wells
    Department of Environmental Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    Environ Health Perspect 119:664-9. 2011
    ..Lead exposure is associated with elevated blood pressure during pregnancy; however, the magnitude of this relationship at low exposure levels is unclear...
  51. pmc Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiological evidence
    Ana Navas-Acien
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205 2223, USA
    Environ Health Perspect 114:641-8. 2006
    ....
  52. pmc Metals in urine and peripheral arterial disease
    Ana Navas-Acien
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 113:164-9. 2005
    ..Other metals in urine were not associated with PAD at the levels found in the general population...
  53. pmc Contribution of company affiliation and social contacts to risk estimates of between-farm transmission of avian influenza
    Jessica H Leibler
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
    PLoS ONE 5:e9888. 2010
    ..The contribution of company affiliation to risk of between-farm disease transmission has not been previously studied...
  54. pmc A niche for infectious disease in environmental health: rethinking the toxicological paradigm
    Beth J Feingold
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 118:1165-72. 2010
    ..We provide evidence that environmental health research would be strengthened through finding common ground with the tools and approaches of infectious disease research...
  55. ncbi request reprint Fetal ADH2*3, maternal alcohol consumption, and fetal growth
    Darryl P Arfsten
    Toxicology Program, University of Maryland, Baltimore, Maryland, USA
    Int J Toxicol 23:47-54. 2004
    ..However, this study has limitations in that it is a "nested study of convenience" and involves a relatively small number of infants born to mothers reporting moderate to heavy alcohol use during pregnancy...
  56. pmc Arsenic: a roadblock to potential animal waste management solutions
    Keeve E Nachman
    Department of Health Policy and Management, Johns Hopkins University, Baltimore, MD 21205, USA
    Environ Health Perspect 113:1123-4. 2005
    ..The removal of arsenic from animal feed is a critical step toward safe poultry waste management...
  57. pmc In vitro interactions between splenocytes and dansylamide dye-embedded nanoparticles detected by flow cytometry
    Jennifer F Nyland
    Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
    Nanomedicine 5:298-304. 2009
    ..These results indicate that NPs may affect cell function at concentrations below those inducing cytotoxicity or apoptosis and demonstrate a novel method to image both localization of NPs and cell-level effects...
  58. pmc Risk of handling as a route of exposure to infectious waterborne Cryptosporidium parvum oocysts via Atlantic blue crabs (Callinectes sapidus)
    Thaddeus K Graczyk
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Appl Environ Microbiol 73:4069-70. 2007
    ..The study demonstrated that blue crabs can transfer C. parvum oocysts to persons involved in handling or preparing crabs and that they may contaminate other surfaces or products during storage...
  59. pmc t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials
    Ellen K Silbergeld
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    ALTEX 28:236-41. 2011
    ..Finally, the group recommended that a reliable, open, curated database be developed that interfaces with existing databases to enable sharing of information...
  60. doi request reprint Predictive models for nanotoxicology: current challenges and future opportunities
    Katherine A Clark
    Dept of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, USA Institute for Work and Health, Universities of Lausanne and Geneva, Switzerland
    Regul Toxicol Pharmacol 59:361-3. 2011
    ..Strategies for directing research towards predictive models and the ancillary benefits of such research are presented here...
  61. ncbi request reprint Household transmission of meticillin-resistant Staphylococcus aureus and other staphylococci
    Meghan F Davis
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet Infect Dis 12:703-16. 2012
    ..Household-based interventions should be developed to control recurrent S aureus infections in the community, and coordination between medical and veterinary providers could be beneficial...
  62. pmc Associations of renal function with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers
    Virginia M Weaver
    Division of Occupational and Environmental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
    Environ Health Perspect 111:1613-9. 2003
    ..08). No significant differences were seen in renal outcomes by VDR genotype, nor was consistent effect modification observed. The ALAD findings could be explained by lead-induced hyperfiltration...
  63. ncbi request reprint Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity
    Sylvia Frisancho-Kiss
    Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA
    J Immunol 176:6411-5. 2006
    ..These results indicate that regulation of inflammation in the heart begins during innate immunity and that Tim-3 signaling on cells of the innate immune system critically influences regulation of the adaptive immune response...
  64. ncbi request reprint Blood lead, blood pressure, and hypertension in perimenopausal and postmenopausal women
    Denis Nash
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    JAMA 289:1523-32. 2003
    ..In perimenopausal women, skeletal lead stores are an important source of endogenous lead exposure due to increased bone demineralization...
  65. pmc Arsenic resistance in Campylobacter spp. isolated from retail poultry products
    Amy R Sapkota
    Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room E6620, Baltimore, MD 21205 2103, USA
    Appl Environ Microbiol 72:3069-71. 2006
    ..Isolates from conventional poultry products had significantly higher roxarsone MICs (z = 8.22; P < 0.0001)...
  66. ncbi request reprint Variability in human metabolism of arsenic
    Christopher A Loffredo
    Program in Human Health and the Environment, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Environ Res 92:85-91. 2003
    ..This analysis highlights the need for continuing research on the health effects of As in humans using molecular epidemiologic methods...
  67. ncbi request reprint Mechanisms of male mediated developmental toxicity induced by lead
    Ellen K Silbergeld
    University of Maryland Baltimore, Department of Epidemiology and Preventive Medicine, 10 South Pine Street, MSTF 9 34, Baltimore, MD 21201, USA
    Adv Exp Med Biol 518:37-48. 2003
  68. pmc Low-dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupus
    Charles S Via
    Research Service, Department of Veteran Affairs Medical Center, Baltimore, Maryland, USA
    Environ Health Perspect 111:1273-7. 2003
    ..These results are consistent with the hypothesis that low-level, nontoxic iHg preexposure may interact with other risk factors, genetic or acquired, to promote subsequent autoimmune disease development...
  69. pmc Risks of recreational exposure to waterborne pathogens among persons with HIV/AIDS in Baltimore, Maryland
    Cynthia C McOliver
    Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Public Health 99:1116-22. 2009
    ..We assessed the prevalence of recreational activities in the waterways of Baltimore, MD, and the risk of exposure to Cryptosporidium among persons with HIV/AIDS...
  70. pmc Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria
    David L Smith
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 99:6434-9. 2002
    ..Our model indicates that the greatest impact occurs very early in the emergence of resistance, when AR bacteria are rare, possibly below the detection limits of current surveillance methods...
  71. pmc Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshop
    John M Balbus
    Environmental Defense, Washington, DC 20009, USA
    Environ Health Perspect 115:1654-9. 2007
    ..Finally, the group identified general policy and strategic opportunities to accelerate the development and implementation of testing protocols and ensure that the information generated is translated effectively for all stakeholders...
  72. ncbi request reprint A probabilistic risk assessment of Cryptosporidium exposure among Baltimore urban anglers
    Jennifer D Roberts
    ChemRisk, San Francisco, CA 94105, USA
    J Toxicol Environ Health A 70:1568-76. 2007
    ..This pilot study provided data for possible modifications and improvements to be made to policy and risk communication regarding the potential health risks due to Cryptosporidium exposure from fishing...
  73. pmc Exposure to metals: are we protecting the workers?
    Ellen K Silbergeld
    Occup Environ Med 64:141-2. 2007
  74. ncbi request reprint Bone density-related predictors of blood lead level among peri- and postmenopausal women in the United States: The Third National Health and Nutrition Examination Survey, 1988-1994
    Denis Nash
    Center for Urban Epidemiologic Studies, New York Academy of Medicine, New York, NY 10029, USA
    Am J Epidemiol 160:901-11. 2004
    ..Lead stored in bone may significantly increase blood lead levels in perimenopausal women because of postmenopausal bone mineral resorption. Attention to factors that prevent bone loss may lessen or prevent this endogenous lead exposure...
  75. pmc Arsenic in food
    Ellen K Silbergeld
    Environ Health Perspect 112:A338-9. 2004
  76. pmc An approach to assessment of endocrine disruption in the National Children's Study
    Matthew P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1691-7. 2003
    ..Nonetheless, if properly designed, the NCS could serve as an excellent resource for investigating future hypotheses regarding endocrine disruption...
  77. ncbi request reprint The International Commission on Occupational Health (ICOH) and its influence on international organizations
    Nicholas A Ashford
    Massachusetts Institute of Technology, USA
    Int J Occup Environ Health 8:156-62. 2002
    ..Official recognition of the ICOH compromises the credibility of the WHO and the ILO. It is inappropriate for the ICOH to continue to receive WHO and ILO recognition unless the ICOH is recognized as an industry organization...
  78. ncbi request reprint Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles
    Lorraine L Marnell
    Department of Molecular and Cellular Biology, Center for Toxicology, University of Arizona, Tucson Arizona 85721 0106, USA
    Chem Res Toxicol 16:1507-13. 2003
    ..The findings suggest the need for further studies to identify unambiguously specific polymorphisms that may account for interindividual variability in the human response to chronic inorganic arsenic exposure...

Research Grants2

  1. Role of Genomic Imprinting in Developmental Neurotoxici*
    Ellen Silbergeld; Fiscal Year: 2003
    ..2. To utilize high throughput methods to examine patterns of DNA methylation in candidate genes in sperm and zygote in order to detect the presence of male-mediated effects on imprinted genes involved in early development. ..
  2. Genetic Susceptibility to Mercury-Induced Immune Dysfunction in Autism & ASD
    Ellen Silbergeld; Fiscal Year: 2007
    ..Accomplishing the goals of this project will be the first stage in developing a broader study of gene-environment interactions in autism, as well as a targeted search for candidate genes related to mercury susceptibility in humans. ..