Research Topics
| Ellen K SilbergeldSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Publications
Evidence-based toxicology: strait is the gate, but the road is worth takingEllen Silbergeld
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
ALTEX 30:67-73. 2013..An evidence-based approach does not obviate the role of judgment and values in decision making; its goal is to ensure provision of all available information in a transparent and unbiased manner...
Low level methylmercury exposure affects neuropsychological function in adultsEdna M Yokoo
Institute of Social Medicine Universidade Estaduel do Rio de Janeiro, Brazil
Environ Health 2:8. 2003..The present study reports on the results of neuropsychological testing and hair mercury concentrations in adults (>17 yrs) living in fishing communities of Baixada Cuiabana (Mato Grosso) in the Pantanal region of Brazil...
Organizational and activational effects of estrogenic endocrine disrupting chemicalsEllen K Silbergeld
Department of Environmental Health Sciences, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cad Saude Publica 18:495-504. 2002....
One reservoir: redefining the community origins of antimicrobial-resistant infectionsEllen K Silbergeld
Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, E6644, Baltimore, MD 21205, USA
Med Clin North Am 92:1391-407, xi. 2008....
The environmental and public health risks associated with arsenical use in animal feedsEllen K Silbergeld
Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland, USA
Ann N Y Acad Sci 1140:346-57. 2008..This continued expansion of arsenical drug use may likely increase the burden of global human arsenic exposure and risk...
Commentary: the role of toxicology in prevention and precautionEllen K Silbergeld
Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21210, USA
Int J Occup Med Environ Health 17:91-102. 2004..Thus, rather than a "new science", advocates for change should focus upon ensuring that current scientific methods are appropriate and that interpretations of scientific data are accurate...
Industrial food animal production, antimicrobial resistance, and human healthEllen K Silbergeld
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Annu Rev Public Health 29:151-69. 2008....
Environmental exposures, toxicologic mechanisms, and adverse pregnancy outcomesEllen K Silbergeld
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Obstet Gynecol 192:S11-21. 2005....
Mercury exposure and malaria prevalence among gold miners in Pará, BrazilEllen K Silbergeld
Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA
Rev Soc Bras Med Trop 35:421-9. 2002....
Environmental exposures and women's healthEllen K Silbergeld
Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland 21205, USA
Clin Obstet Gynecol 45:1119-28. 2002
Mercury and autoimmunity: implications for occupational and environmental healthEllen K Silbergeld
Department of Environmental Health Sciences, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Toxicol Appl Pharmacol 207:282-92. 2005..These results suggest a new model for Hg immunotoxicity, as a co-factor in autoimmune disease, increasing the risks and severity of clinical disease in the presence of other triggering events, either genetic or acquired...
Facilitative mechanisms of lead as a carcinogenEllen K Silbergeld
Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Mutat Res 533:121-33. 2003..Some of these events may also be relevant to understanding mechanisms of lead-induced reproductive toxicity...
Effect modification by delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase gene polymorphisms on associations between patella lead and renal function in lead workersVirginia M Weaver
Division of Occupational and Environmental Health, Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Environ Res 102:61-9. 2006..In conclusion, VDR and/or ALAD genotypes modified associations between all the lead biomarkers, except patella lead, and the renal outcomes...
Associations of patella lead with polymorphisms in the vitamin D receptor, delta-aminolevulinic acid dehydratase and endothelial nitric oxide synthase genesKeson Theppeang
Departments of Environmental Health Sciences, Johns Hopkins School of Medicine and Bloomberg School of Public Health, Baltimore, Maryland, USA
J Occup Environ Med 46:528-37. 2004..6 microg Pb/g bone mineral) than lead workers with the VDR bb genotype. There was evidence that the relation between age and patella lead was modified by both the VDR and eNOS genotypes...
Associations of uric acid with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workersVirginia M Weaver
Division of Occupational and Environmental Health, Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 113:1509-15. 2005..We conclude that genetic polymorphisms may modify uric acid mediation of lead-related adverse renal effects...
The G(894)-T(894) polymorphism in the gene for endothelial nitric oxide synthase and blood pressure in lead-exposed workers from KoreaMark E Lustberg
Department of Epidemiology and Preventive Medicine, University of Maryland Baltimore, Baltimore, Maryland 21205, USA
J Occup Environ Med 46:584-90. 2004..These data provide no evidence that the T allele is associated with higher blood pressure or modifies the association of lead dose with blood pressure...
Mercury exposure, serum antinuclear/antinucleolar antibodies, and serum cytokine levels in mining populations in Amazonian Brazil: a cross-sectional studyRenee M Gardner
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Baltimore, MD 21205, USA
Environ Res 110:345-54. 2010..This study provides further evidence that mercury exposure may lead to autoimmune dysfunction and systemic inflammation in affected populations...
Arsenic exposure, diabetes prevalence, and diabetes control in the Strong Heart StudyMatthew O Gribble
Departments of Environmental Health Sciences and Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Room W7513D, Baltimore, MD 21205, USA
Am J Epidemiol 176:865-74. 2012..Prospective studies that evaluate the direction of the relation between poor diabetes control and arsenic exposure are needed...
Industrial food animal production and global health risks: exploring the ecosystems and economics of avian influenzaJessica H Leibler
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Ecohealth 6:58-70. 2009..In order to more effectively reduce zoonotic disease risk from industrial food animal production, private incentives for the implementation of biosecurity must align with public health interests...
Confounding of the relation between homocysteine and peripheral arterial disease by lead, cadmium, and renal functionEliseo Guallar
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Am J Epidemiol 163:700-8. 2006..The association of lead and cadmium with PAD risk deserves further investigation...
Arsenic exposure and prevalence of type 2 diabetes in US adultsAna Navas-Acien
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room W7033B, Baltimore, MD 21205, USA
JAMA 300:814-22. 2008..In contrast, arsenobetaine, an organic arsenic compound derived from seafood intake, is considered nontoxic...
Antibiotic resistant enterococci and staphylococci isolated from flies collected near confined poultry feeding operationsJay P Graham
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Division of Environmental Health Engineering, Baltimore, MD 21205, USA
Sci Total Environ 407:2701-10. 2009..We report that flies collected near broiler poultry operations may be involved in the spread of drug resistant bacteria from these operations and may increase the potential for human exposure to drug resistant bacteria...
Arsenic exposure and cardiovascular disease: a systematic review of the epidemiologic evidenceAna Navas-Acien
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2223, USA
Am J Epidemiol 162:1037-49. 2005..In other populations or in occupational settings, the evidence was inconclusive. Because of the high prevalence of arsenic exposure, carefully performed studies of arsenic and cardiovascular outcomes should be a research priority...
Food animal transport: a potential source of community exposures to health hazards from industrial farming (CAFOs)Ana M Rule
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Division of Environmental Health Engineering, Baltimore, MD 21205 USA
J Infect Public Health 1:33-9. 2008..These findings support the need for further exposure characterization, and attention to improving methods of food animal transport, especially in highly trafficked regions of high density farming such as the Delmarva Peninsula...
Bone lead levels and blood pressure endpoints: a meta-analysisAna Navas-Acien
Department of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Epidemiology 19:496-504. 2008..We performed a meta-analysis of the association of bone lead levels with systolic blood pressure, diastolic blood pressure, and hypertension using published data...
Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in Amazon populations in Brazil: a cross-sectional studyInes A Silva
The Johns Hopkins University Bloomberg School of Public Health, 615 N, Wolfe Street, Room E6642, Baltimore, Maryland 21201, USA
Environ Health 3:11. 2004..A few studies have examined relationships between mercury exposures and adverse immunological reactions in humans, but there is little evidence of mercury-associated autoimmunity in humans...
Seafood intake and urine concentrations of total arsenic, dimethylarsinate and arsenobetaine in the US populationAna Navas-Acien
Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Environ Res 111:110-8. 2011..Seafood is the main source of organic arsenic exposure (arsenobetaine, arsenosugars and arsenolipids) in the population. Arsenosugars and arsenolipids are metabolized to several species including dimethylarsinate (DMA)...
The animal-human interface and infectious disease in industrial food animal production: rethinking biosecurity and biocontainmentJay P Graham
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Division of Environmental Health Engineering, Baltimore, MD 21205, USA
Public Health Rep 123:282-99. 2008..These data suggest that successful strategies to prevent or mitigate the emergence of pandemic avian influenza must consider risk factors specific to modern industrialized food animal production...
Cadmium exposure and incident cardiovascular diseaseMaria Tellez-Plaza
Department of Epidemiology and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Epidemiology 24:421-9. 2013..We evaluated the association of urine cadmium concentration with cardiovascular disease incidence and mortality in a large population-based cohort...
Urine arsenic and prevalent albuminuria: evidence from a population-based studyLaura Y Zheng
Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Kidney Dis 61:385-94. 2013..Our objective was to evaluate the cross-sectional association between inorganic arsenic exposure and albuminuria in American Indian adults from rural areas of Arizona, Oklahoma, and North and South Dakota...
Lead exposure and cardiovascular disease--a systematic reviewAna Navas Acien
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 115:472-82. 2007..This systematic review evaluates the evidence on the association between lead exposure and cardiovascular end points in human populations...
Heritability and preliminary genome-wide linkage analysis of arsenic metabolites in urineMaria Tellez-Plaza
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 121:345-51. 2013..Arsenic (III) methyltransferase (AS3MT) has been related to urine arsenic metabolites in association studies. Other genes might also play roles in arsenic metabolism and excretion...
Household Risk Factors for Colonization with Multidrug-Resistant Staphylococcus aureus IsolatesMeghan F Davis
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS ONE 8:e54733. 2013..Understanding drivers of antimicrobial resistance in MRSA isolates is important to hospital infection control efforts, relevant to patient outcomes and to indicators of the economic burden of antimicrobial resistance...
Differential immunotoxic effects of inorganic and organic mercury species in vitroRenee M Gardner
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N Wolfe St, Baltimore, MD 21205, United States
Toxicol Lett 198:182-90. 2010..These results indicate that both organic and inorganic species of Hg can affect the human immune system, but that they may exert different effects on immune function...
Fate of antimicrobial-resistant enterococci and staphylococci and resistance determinants in stored poultry litterJay P Graham
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Environ Res 109:682-9. 2009..This study indicates that typical storage practices of poultry litter are insufficient for eliminating drug-resistant enterococci and staphylococci, which may then be released into the environment through land disposal...
Fetal and maternal immune responses to methylmercury exposure: a cross-sectional studyJennifer F Nyland
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615N Wolfe Street, Baltimore, MD 21205, USA
Environ Res 111:584-9. 2011..However, unlike previous data from adult males and non-pregnant females, we found no evidence that antinuclear and antinucleolar autoantibody titer is a reliable biomarker of mercury immunotoxicity in this population...
Molecular and phenotypic characteristics of healthcare- and community-associated methicillin-resistant Staphylococcus aureus at a rural hospitalAmy E Peterson
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS ONE 7:e38354. 2012..While methicillin-resistant Staphylococcus aureus (MRSA) originally was associated with healthcare, distinct strains later emerged in patients with no prior hospital contact. The epidemiology of MRSA continues to evolve...
Prevalence of potentially neuropathic Campylobacter jejuni strains on commercial broiler chicken productsChristopher G Hardy
Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Int J Food Microbiol 145:395-9. 2011..In terms of cstII polymorphisms, there were also similarities between isolates from poultry and those from patients with GBS and MFS...
Cadmium levels in urine and mortality among U.S. adultsAndy Menke
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 117:190-6. 2009..However, studies investigating this association have included participants with considerably higher levels of cadmium than those found in the general population...
An ecological perspective on U.S. industrial poultry production: the role of anthropogenic ecosystems on the emergence of drug-resistant bacteria from agricultural environmentsMeghan F Davis
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States
Curr Opin Microbiol 14:244-50. 2011....
Low-level lead exposure and elevations in blood pressure during pregnancyEllen M Wells
Department of Environmental Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Environ Health Perspect 119:664-9. 2011..Lead exposure is associated with elevated blood pressure during pregnancy; however, the magnitude of this relationship at low exposure levels is unclear...
Contribution of company affiliation and social contacts to risk estimates of between-farm transmission of avian influenzaJessica H Leibler
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS ONE 5:e9888. 2010..The contribution of company affiliation to risk of between-farm disease transmission has not been previously studied...
Metals in urine and peripheral arterial diseaseAna Navas-Acien
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 113:164-9. 2005..Other metals in urine were not associated with PAD at the levels found in the general population...
Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiological evidenceAna Navas-Acien
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205 2223, USA
Environ Health Perspect 114:641-8. 2006....
Livestock density as risk factor for livestock-associated methicillin-resistant Staphylococcus aureus, the NetherlandsBeth J Feingold
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA
Emerg Infect Dis 18:1841-9. 2012..Controlling the spread of LA-MRSA thus requires giving attention to community members in animal-dense regions who are unaffiliated with livestock farming...
Fetal ADH2*3, maternal alcohol consumption, and fetal growthDarryl P Arfsten
Toxicology Program, University of Maryland, Baltimore, Maryland, USA
Int J Toxicol 23:47-54. 2004..However, this study has limitations in that it is a "nested study of convenience" and involves a relatively small number of infants born to mothers reporting moderate to heavy alcohol use during pregnancy...
Mercury induces an unopposed inflammatory response in human peripheral blood mononuclear cells in vitroRenee M Gardner
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Environ Health Perspect 117:1932-8. 2009..Dysregulation of cytokine signaling appears to play an important role in the etiology of Hg-induced autoimmunity in animal models...
Urine arsenic concentrations and species excretion patterns in American Indian communities over a 10-year period: the Strong Heart StudyAna Navas-Acien
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Environ Health Perspect 117:1428-33. 2009..Arsenic exposure in drinking water disproportionately affects small communities in some U.S. regions, including American Indian communities. In U.S. adults with no seafood intake, median total urine arsenic is 3.4 microg/L...
In vitro interactions between splenocytes and dansylamide dye-embedded nanoparticles detected by flow cytometryJennifer F Nyland
Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
Nanomedicine 5:298-304. 2009..NPs also induced a range of biological signals consistent with activation and costimulation...
Arsenic: a roadblock to potential animal waste management solutionsKeeve E Nachman
Department of Health Policy and Management, Johns Hopkins University, Baltimore, MD 21205, USA
Environ Health Perspect 113:1123-4. 2005..The removal of arsenic from animal feed is a critical step toward safe poultry waste management...
Risk of handling as a route of exposure to infectious waterborne Cryptosporidium parvum oocysts via Atlantic blue crabs (Callinectes sapidus)Thaddeus K Graczyk
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N Wolfe Street, Baltimore, MD 21205, USA
Appl Environ Microbiol 73:4069-70. 2007..The study demonstrated that blue crabs can transfer C. parvum oocysts to persons involved in handling or preparing crabs and that they may contaminate other surfaces or products during storage...
Correlation between animal nasal carriage and environmental methicillin-resistant Staphylococcus aureus isolates at U.S. horse and cattle farmsAmy E Peterson
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, United States Electronic address
Vet Microbiol 160:539-43. 2012..The methods presented here may aid in surveillance efforts for equine and other animal MRSA. This study successfully applies existing MRSA surveillance methods for indoor, high animal density settings to outdoor and low-density farms...
Household transmission of meticillin-resistant Staphylococcus aureus and other staphylococciMeghan F Davis
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet Infect Dis 12:703-16. 2012..Household-based interventions should be developed to control recurrent S aureus infections in the community, and coordination between medical and veterinary providers could be beneficial...
Arsenic resistance in Campylobacter spp. isolated from retail poultry productsAmy R Sapkota
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room E6620, Baltimore, MD 21205 2103, USA
Appl Environ Microbiol 72:3069-71. 2006..Isolates from conventional poultry products had significantly higher roxarsone MICs (z = 8.22; P < 0.0001)...
A niche for infectious disease in environmental health: rethinking the toxicological paradigmBeth J Feingold
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 118:1165-72. 2010..We provide evidence that environmental health research would be strengthened through finding common ground with the tools and approaches of infectious disease research...
Blood lead, blood pressure, and hypertension in perimenopausal and postmenopausal womenDenis Nash
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
JAMA 289:1523-32. 2003..In perimenopausal women, skeletal lead stores are an important source of endogenous lead exposure due to increased bone demineralization...
Associations of renal function with polymorphisms in the delta-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workersVirginia M Weaver
Division of Occupational and Environmental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 111:1613-9. 2003..08). No significant differences were seen in renal outcomes by VDR genotype, nor was consistent effect modification observed. The ALAD findings could be explained by lead-induced hyperfiltration...
Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunitySylvia Frisancho-Kiss
Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA
J Immunol 176:6411-5. 2006..These results indicate that regulation of inflammation in the heart begins during innate immunity and that Tim-3 signaling on cells of the innate immune system critically influences regulation of the adaptive immune response...
Antimicrobial-resistant Bacteria: An Unrecognized Work-related Risk in Food Animal ProductionRicardo Castillo Neyra
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Saf Health Work 3:85-91. 2012..These risks are not yet recognized by any work-related health and safety agency in the world...
t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterialsEllen K Silbergeld
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
ALTEX 28:236-41. 2011..Finally, the group recommended that a reliable, open, curated database be developed that interfaces with existing databases to enable sharing of information...
Low-dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupusCharles S Via
Research Service, Department of Veteran Affairs Medical Center, Baltimore, Maryland, USA
Environ Health Perspect 111:1273-7. 2003..These results are consistent with the hypothesis that low-level, nontoxic iHg preexposure may interact with other risk factors, genetic or acquired, to promote subsequent autoimmune disease development...
Variability in human metabolism of arsenicChristopher A Loffredo
Program in Human Health and the Environment, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Environ Res 92:85-91. 2003..This analysis highlights the need for continuing research on the health effects of As in humans using molecular epidemiologic methods...
Mechanisms of male mediated developmental toxicity induced by leadEllen K Silbergeld
University of Maryland Baltimore, Department of Epidemiology and Preventive Medicine, 10 South Pine Street, MSTF 9-34, Baltimore, MD 21201, USA
Adv Exp Med Biol 518:37-48. 2003
Predictive models for nanotoxicology: current challenges and future opportunitiesKatherine A Clark
Dept of Environmental Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, USA Institute for Work and Health, Universities of Lausanne and Geneva, Switzerland
Regul Toxicol Pharmacol 59:361-3. 2011..Strategies for directing research towards predictive models and the ancillary benefits of such research are presented here...
Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteriaDavid L Smith
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Proc Natl Acad Sci U S A 99:6434-9. 2002..Our model indicates that the greatest impact occurs very early in the emergence of resistance, when AR bacteria are rare, possibly below the detection limits of current surveillance methods...
Risks of recreational exposure to waterborne pathogens among persons with HIV/AIDS in Baltimore, MarylandCynthia C McOliver
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Public Health 99:1116-22. 2009..We assessed the prevalence of recreational activities in the waterways of Baltimore, MD, and the risk of exposure to Cryptosporidium among persons with HIV/AIDS...
Arsenic in foodEllen K Silbergeld
Environ Health Perspect 112:A338-9. 2004
Bone density-related predictors of blood lead level among peri- and postmenopausal women in the United States: The Third National Health and Nutrition Examination Survey, 1988-1994Denis Nash
Center for Urban Epidemiologic Studies, New York Academy of Medicine, New York, NY 10029, USA
Am J Epidemiol 160:901-11. 2004..Lead stored in bone may significantly increase blood lead levels in perimenopausal women because of postmenopausal bone mineral resorption. Attention to factors that prevent bone loss may lessen or prevent this endogenous lead exposure...
A probabilistic risk assessment of Cryptosporidium exposure among Baltimore urban anglersJennifer D Roberts
ChemRisk, San Francisco, CA 94105, USA
J Toxicol Environ Health A 70:1568-76. 2007..This pilot study provided data for possible modifications and improvements to be made to policy and risk communication regarding the potential health risks due to Cryptosporidium exposure from fishing...
Exposure to metals: are we protecting the workers?Ellen K Silbergeld
Occup Environ Med 64:141-2. 2007
Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adultsAndy Menke
Department of Epidemiology, Tulane University SPHTM, 1430 Tulane Ave, New Orleans, LA 70112, USA
Circulation 114:1388-94. 2006..Despite the marked decrease in blood lead levels over the past 3 decades, environmental lead exposures remain a significant determinant of cardiovascular mortality in the general population, constituting a major public health problem...
Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshopJohn M Balbus
Environmental Defense, Washington, DC 20009, USA
Environ Health Perspect 115:1654-9. 2007..Finally, the group identified general policy and strategic opportunities to accelerate the development and implementation of testing protocols and ensure that the information generated is translated effectively for all stakeholders...
Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profilesLorraine L Marnell
Department of Molecular and Cellular Biology, Center for Toxicology, University of Arizona, Tucson Arizona 85721-0106, USA
Chem Res Toxicol 16:1507-13. 2003..The findings suggest the need for further studies to identify unambiguously specific polymorphisms that may account for interindividual variability in the human response to chronic inorganic arsenic exposure...
An approach to assessment of endocrine disruption in the National Children's StudyMatthew P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:1691-7. 2003..Nonetheless, if properly designed, the NCS could serve as an excellent resource for investigating future hypotheses regarding endocrine disruption...
The International Commission on Occupational Health (ICOH) and its influence on international organizationsNicholas A Ashford
Massachusetts Institute of Technology, USA
Int J Occup Environ Health 8:156-62. 2002..Official recognition of the ICOH compromises the credibility of the WHO and the ILO. It is inappropriate for the ICOH to continue to receive WHO and ILO recognition unless the ICOH is recognized as an industry organization...
Research Grants
- Role of Genomic Imprinting in Developmental Neurotoxici*Ellen Silbergeld; Fiscal Year: 2003..2. To utilize high throughput methods to examine patterns of DNA methylation in candidate genes in sperm and zygote in order to detect the presence of male-mediated effects on imprinted genes involved in early development. ..
- Genetic Susceptibility to Mercury-Induced Immune Dysfunction in Autism & ASDEllen Silbergeld; Fiscal Year: 2007..Accomplishing the goals of this project will be the first stage in developing a broader study of gene-environment interactions in autism, as well as a targeted search for candidate genes related to mercury susceptibility in humans. ..
