George K Siberry

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Antibody response to hepatitis A immunization among human immunodeficiency virus-infected children and adolescents
    George K Siberry
    Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Infect Dis J 27:465-8. 2008
  2. pmc Aggregate risk of cardiovascular disease among adolescents perinatally infected with the human immunodeficiency virus
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, MA K P, G R S Center for Biostatistics in AIDS Research, Boston, MA K P, J W, D L J, G R S, P L W Department of Pediatrics, Wayne State University School of Medicine, Children s Hospital of Michigan, Detroit S E L Division of Pediatric Clinical Research and Division of Pediatric Infectious Disease and Immunology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL D C L, G B S, J D W, T L M Saban Research Institute of Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA M E G Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis L A D M Department of Pediatrics, Tulane University Health Sciences Center, New Orleans, LA R B V D Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD G K S Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston W T S Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, IL L Y Division of Cardiology, University of Maryland School of Medicine, Brazil
    Circulation 129:1204-12. 2014
  3. ncbi request reprint Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy
    Deborah Persaud
    Department of Pediatrics and Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    AIDS Res Hum Retroviruses 23:381-90. 2007
  4. pmc Predictors of highly active antiretroviral therapy utilization for behaviorally HIV-1-infected youth: impact of adult versus pediatric clinical care site
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Adolesc Health 50:471-7. 2012
  5. pmc CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruption
    George K Siberry
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 57:223-9. 2011
  6. ncbi request reprint No decrease in clindamycin susceptibility despite increased use of clindamycin for pediatric community-associated methicillin-resistant Staphylococcus aureus skin infections
    Jillian M Szczesiul
    Department of Pharmacy, The Johns Hopkins Hospital, The Johns Hopkins University, Baltimore, MD, USA
    Pediatr Infect Dis J 26:852-4. 2007
  7. pmc Disparities in antiretroviral treatment: a comparison of behaviorally HIV-infected youth and adults in the HIV Research Network
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 58:100-7. 2011
  8. pmc Bone mineral density in children and adolescents with perinatal HIV infection
    Linda A DiMeglio
    Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
    AIDS 27:211-20. 2013
  9. doi request reprint Correlates of sexual activity and sexually transmitted infections among human immunodeficiency virus-infected youth in the LEGACY cohort, United States, 2006
    Rosanna W Setse
    Department of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 30:967-73. 2011
  10. pmc Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Clin Immunol 142:201-8. 2012

Detail Information

Publications39

  1. ncbi request reprint Antibody response to hepatitis A immunization among human immunodeficiency virus-infected children and adolescents
    George K Siberry
    Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Infect Dis J 27:465-8. 2008
    ..In multivariate analysis, CD4 >or=25% and young age were independent predictors of HAV seropositivity. Of 7 children given a third HAV vaccine dose because of negative HAV antibody after 2 doses, 2 (29%) became seropositive...
  2. pmc Aggregate risk of cardiovascular disease among adolescents perinatally infected with the human immunodeficiency virus
    Kunjal Patel
    Department of Epidemiology, Harvard School of Public Health, Boston, MA K P, G R S Center for Biostatistics in AIDS Research, Boston, MA K P, J W, D L J, G R S, P L W Department of Pediatrics, Wayne State University School of Medicine, Children s Hospital of Michigan, Detroit S E L Division of Pediatric Clinical Research and Division of Pediatric Infectious Disease and Immunology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL D C L, G B S, J D W, T L M Saban Research Institute of Children s Hospital Los Angeles, Keck School of Medicine of USC, Los Angeles, CA M E G Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis L A D M Department of Pediatrics, Tulane University Health Sciences Center, New Orleans, LA R B V D Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD G K S Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston W T S Department of Pediatrics, Northwestern University Feinberg School of Medicine, Children s Memorial Hospital, Chicago, IL L Y Division of Cardiology, University of Maryland School of Medicine, Brazil
    Circulation 129:1204-12. 2014
    ....
  3. ncbi request reprint Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy
    Deborah Persaud
    Department of Pediatrics and Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    AIDS Res Hum Retroviruses 23:381-90. 2007
    ..The effect of early therapy on HIV-1 evolution may have implications for long-term pharmacologic control of HIV-1...
  4. pmc Predictors of highly active antiretroviral therapy utilization for behaviorally HIV-1-infected youth: impact of adult versus pediatric clinical care site
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Adolesc Health 50:471-7. 2012
    ..We assessed the impact of receiving care at an adult or pediatric HIV clinical site on initiation and discontinuation of the first HAART regimen in behaviorally infected youth (BIY)...
  5. pmc CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruption
    George K Siberry
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 57:223-9. 2011
    ..To assess the characteristics and outcomes of antiretroviral treatment (ART) interruption (TI) in perinatally HIV-infected children...
  6. ncbi request reprint No decrease in clindamycin susceptibility despite increased use of clindamycin for pediatric community-associated methicillin-resistant Staphylococcus aureus skin infections
    Jillian M Szczesiul
    Department of Pharmacy, The Johns Hopkins Hospital, The Johns Hopkins University, Baltimore, MD, USA
    Pediatr Infect Dis J 26:852-4. 2007
    ..Despite a significant increase in empiric clindamycin use, 97% of community-associated-MRSA isolates retained susceptibility to clindamycin...
  7. pmc Disparities in antiretroviral treatment: a comparison of behaviorally HIV-infected youth and adults in the HIV Research Network
    Allison L Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 58:100-7. 2011
    ..We hypothesized that behaviorally HIV-infected youth (BIY) ages 18 to 24 years are less likely than adults (25 years or older) to receive HAART and, once initiated, more likely to discontinue their first HAART regimen...
  8. pmc Bone mineral density in children and adolescents with perinatal HIV infection
    Linda A DiMeglio
    Section of Pediatric Endocrinology and Diabetology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
    AIDS 27:211-20. 2013
    ..To estimate prevalence of low bone mineral density (BMD) in perinatally HIV-infected (HIV+) and HIV-exposed but uninfected (HEU) children, and to determine predictors of BMD in HIV+...
  9. doi request reprint Correlates of sexual activity and sexually transmitted infections among human immunodeficiency virus-infected youth in the LEGACY cohort, United States, 2006
    Rosanna W Setse
    Department of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 30:967-73. 2011
    ..To determine the prevalence and correlates of sexual activity and sexually transmitted infections (STIs) among human immunodeficiency virus (HIV)-infected youth...
  10. pmc Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Clin Immunol 142:201-8. 2012
    ..29%, p = 0.010). HIV-infected children and adolescents in this study had an increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide...
  11. ncbi request reprint Thinking about HIV infection
    Evelyn P Simpkins
    Division of General Pediatrics and Adolescent Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Pediatr Rev 30:337-48; quiz 349. 2009
    ..Recommendations for immunizations and chemoprophylaxis vary with the patient's CD4 count. Condoms made from latex, polyurethane, or other synthetic materials have been shown to decrease the transmission of STIs, including HIV infection...
  12. ncbi request reprint Multidisciplinary, inpatient directly observed therapy for HIV-1-infected children and adolescents failing HAART: A retrospective study
    Genevieve N Parsons
    Division of General Pediatrics and Adolescent Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    AIDS Patient Care STDS 20:275-84. 2006
    ....
  13. pmc Antiretroviral treatment of US children with perinatally acquired HIV infection: temporal changes in therapy between 1991 and 2009 and predictors of immunologic and virologic outcomes
    Russell B Van Dyke
    Department of Pediatrics, Tulane University Health Sciences Center, New Orleans, LA, USA
    J Acquir Immune Defic Syndr 57:165-73. 2011
    ..We sought to describe the disease status of a large cohort of such children and identify predictors of their current CD4 count and HIV viral load (VL)...
  14. ncbi request reprint Patient-, provider-, and clinic-level predictors of unrecognized elevated blood pressure in children
    Tammy M Brady
    MHS, Johns Hopkins University, David M Rubenstein Child Health Building, 200 North Wolfe St, Room 3057, Baltimore, MD 21287, USA
    Pediatrics 125:e1286-93. 2010
    ..We hypothesized that being of healthy weight, having a BP of <120/80 mmHg, and being seen by a less experienced provider would result in decreased recognition...
  15. ncbi request reprint Discordance between Staphylococcus aureus nasal colonization and skin infections in children
    Aaron E Chen
    Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Infect Dis J 28:244-6. 2009
    ..aureus, but significant discordance between nasal and wound isolates. Recurrent skin and soft tissue infections were common but unrelated to baseline methicillin-resistant S. aureus nasal colonization status...
  16. ncbi request reprint Continuity-structured clinical observations: assessing the multiple-observer evaluation in a pediatric resident continuity clinic
    Karen P Zimmer
    Johns Hopkins University, Department of Pediatrics, 200 North Wolfe St, Baltimore, MD 21287, USA
    Pediatrics 121:e1633-45. 2008
    ..The objectives were to assess pediatric resident performance in a continuity clinic by using direct observation and to compare evaluations among preceptors, residents, and parents...
  17. pmc Randomized controlled trial of cephalexin versus clindamycin for uncomplicated pediatric skin infections
    Aaron E Chen
    Johns Hopkins University, Department of Pediatrics, Division of Pediatric Emergency Medicine, CMSC 144, 600 N Wolfe St, Baltimore, MD 21287, USA
    Pediatrics 127:e573-80. 2011
    ..We hypothesized that clindamycin would be superior to cephalexin (an antibiotic without MRSA activity) for treatment of these infections...
  18. ncbi request reprint Antimicrobial-resistant Shigella sonnei: limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility
    Sanjay K Jain
    Division of Pediatric Infectious Diseases, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Pediatr Infect Dis J 24:494-7. 2005
    ..Antimicrobial-resistant Shigella sonnei is a growing problem in the United States and poses treatment challenges particularly among children. Azithromycin is recommended as an alternative oral agent for shigellosis...
  19. ncbi request reprint Cerebrospinal fluid penetration and bacteriostatic activity of linezolid against Enterococcus faecalis in a child with a ventriculoperitoneal shunt infection
    Aaron M Milstone
    Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Pediatr Neurosurg 43:406-9. 2007
    ..faecalis. Linezolid may be a good alternative for treatment of ventriculoperitoneal shunt infections in cases of vancomycin-resistant organisms or apparent treatment failures...
  20. ncbi request reprint Failure of clindamycin treatment of methicillin-resistant Staphylococcus aureus expressing inducible clindamycin resistance in vitro
    George K Siberry
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Clin Infect Dis 37:1257-60. 2003
    ..aureus isolates from pediatric patients. Our clinical laboratory currently tests all S. aureus isolates for iMLS before reporting clindamycin susceptibility...
  21. ncbi request reprint Evolving epidemiology of pediatric Staphylococcus aureus cutaneous infections in a Baltimore hospital
    Aaron E Chen
    Department of Pediatrics, The Johns Hopkins University, Baltimore, MD, USA
    Pediatr Emerg Care 22:717-23. 2006
    ....
  22. ncbi request reprint Low prevalence of pertussis among children admitted with respiratory symptoms during respiratory syncytial virus season
    George K Siberry
    Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Infect Control Hosp Epidemiol 27:95-7. 2006
    ..6%) of 166 children admitted to the hospital during RSV season were Bordetella pertussis PCR positive during a nonepidemic period. These data show that screening may not be useful when pertussis prevalence is low...
  23. pmc Perinatally HIV-infected youth presenting with acute stroke: progression/evolution of ischemic disease on neuroimaging
    Izlem Izbudak
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Neuroradiol 40:172-80. 2013
    ..Increased risk of acute stroke has been reported in PHIV children. Our goal was to evaluate evolution/progression of neuroimaging findings in PHIV youth initially presenting with acute stroke...
  24. pmc Cardiac biomarkers in HIV-exposed uninfected children
    James D Wilkinson
    Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida 33101, USA
    AIDS 27:1099-108. 2013
    ..To evaluate associations of cardiac biomarkers with in-utero antiretroviral drug exposures and cardiac function/structure measured by echocardiograms in HIV-exposed but uninfected (HEU) children...
  25. pmc Cervical pap screening cytological abnormalities among HIV-infected adolescents in the LEGACY cohort
    Rosanna Setse
    Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Pediatr Adolesc Gynecol 25:27-34. 2012
    ..To determine the prevalence of cervical Pap screening (CPAP-S), identify factors associated with CPAP-S, and explore risk factors for abnormal cervical cytology in female adolescents with perinatally and behaviorally acquired HIV infection...
  26. pmc Incidence of and risk factors for community acquired pneumonia in US HIV-infected children, 2000-2005
    Andrew P Steenhoff
    Department of Pediatrics, Children s Hospital Philadelphia, Pennsylvania, USA
    AIDS 25:717-20. 2011
    ..98; confidence interval 1.05-15.13) was associated with CAP. Herd immunity through pneumococcal immunization may have diluted the effect of individual immunization in this cohort...
  27. pmc Safety and immunogenicity of quadrivalent meningococcal conjugate vaccine in 2- to 10-year-old human immunodeficiency virus-infected children
    George K Siberry
    Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
    Pediatr Infect Dis J 31:47-52. 2012
    ....
  28. ncbi request reprint Nontypeable Haemophilus influenzae meningitis complicated by hearing loss in a 9-year-old HIV-infected boy
    Allison George Agwu
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    AIDS Patient Care STDS 20:531-5. 2006
    ..Placement of cochlear implant improved hearing thresholds. Nontypeable H. influenzae meningitis and use of cochlear implants have not previously been in HIV-infected children...
  29. ncbi request reprint Ritonavir-fluticasone interaction causing Cushing syndrome in HIV-infected children and adolescents
    Renata Arrington-Sanders
    Division of General Pediatrics and Adolescent Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD 20724, USA
    Pediatr Infect Dis J 25:1044-8. 2006
    ..Three patients, all receiving ritonavir-fluticasone, developed weight gain and altered fat distribution concerning for either lipodystrophy or CS...
  30. pmc Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads
    Deborah Persaud
    Department of Pediatrics, Johns Hopkins University School of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21205, USA
    J Virol 78:968-79. 2004
    ..Thus, in most children on HAART with clinically undetectable viremia, there is continued virus production without evolution of resistance in the protease gene...
  31. ncbi request reprint Immune reconstitution syndrome precipitated by bacille Calmette Guerin after initiation of antiretroviral therapy
    George K Siberry
    Division of Pediatric Infectious Diseases and General Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Infect Dis J 25:648-9. 2006
    ..We report the earliest onset of BCG-related immune reconstitution syndrome developing 1 week after initiation of ART...
  32. pmc A mechanistic role for type III IFN-λ1 in asthma exacerbations mediated by human rhinoviruses
    E Kathryn Miller
    Department of Pediatrics, Vanderbilt University, Nashville, TN 37232, USA
    Am J Respir Crit Care Med 185:508-16. 2012
    ..Moreover, although several hypotheses have been advanced to explain virus-induced exacerbations, their mechanism remains unclear...
  33. ncbi request reprint Increase in tuberculin skin test converters among health care workers after a change from Tubersol to Aplisol
    Kari A Gillenwater
    Department of Pediatrics, Johns Hopkins Medical Institutions, 200 N Wolfe Street, Baltimore, MD 21287, USA
    Am J Infect Control 34:651-4. 2006
    ....
  34. ncbi request reprint Comparison of temple temperatures with rectal temperatures in children under two years of age
    George K Siberry
    Department of Pediatrics, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA
    Clin Pediatr (Phila) 41:405-14. 2002
    ..The findings do not support use of temple temperatures to screen young infants for rectal fever > or =38.0 degrees C. Temperatures obtained by parents were comparable to those obtained by nurses...
  35. ncbi request reprint Immunologic function and virologic suppression among children with perinatally acquired HIV Infection on highly active antiretroviral therapy
    Richard M Rutstein
    Division of General Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Med Care 43:III15-22. 2005
    ..Limited data are available on the level of virologic suppression and immune function of pediatric patients followed in clinical settings in the HAART era...
  36. ncbi request reprint Hospital and outpatient health services utilization among HIV-infected children in care 2000-2001
    Richard M Rutstein
    Division of General Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Med Care 43:III31-9. 2005
    ..The aging of the pediatric HIV cohort and advances in antiretroviral therapy for children may have resulted in recent changes in patterns of healthcare utilization...
  37. ncbi request reprint Management of infants born to HIV infected mothers
    George K Siberry
    Hopkins HIV Rep 15:7-9, 12. 2003
  38. doi request reprint Growing up with perinatal HIV infection: time for a HAART to heart
    George K Siberry
    J Pediatr 153:456-7. 2008
  39. ncbi request reprint Corticosteroids for bacterial meningitis
    George K Siberry
    N Engl J Med 358:1400; author reply 1400-1. 2008